Cystogenesis (Advances in Experimental Medicine and Biology) 1st ed. 2016 Edition

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This book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experience renal failure and require dialysis or a renal transplantation. There are no specific targeted therapies for ADPKD currently available, making it important to understand the basic cellular mechanisms underlying the onset and progression of ADPKD, in order to identify potential therapeutic targets for the disease.

Several therapeutic approaches that have been attempted to date are reviewed. This work provides a broad overview of ADPKD and highlights the key challenges currently faced by researchers in this field. Furthermore, it provides insight into ADPKD to facilitate the development of novel biomarkers for ADPKD and to direct future research into this challenging pathology.

This book is suitable for clinicians who have encountered patients with ADPKD, for clinicians / researchers working in the field of ADPKD and more generally on the kidney and kidney related disorders and for students of medicine with an interest in internal medicine.

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Child Psychotherapy Homework Planner (PracticePlanners) 5th Edition

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The Child Psychotherapy Homework Planner, Fifth Edition provides you with an array of ready-to-use, between-session assignments designed to fit virtually every therapeutic mode. This easy-to-use sourcebook features:

  • 93 ready-to-copy exercises covering the most common issues encountered by children, such as academic underachievement, low self-esteem, depression, and separation anxiety
  • A quick-reference format—the interactive assignments are grouped by behavioral problems including blended family problems, divorce reaction, ADHD, attachment disorder, social anxiety, language disorders, and unresolved grief and loss
  • Expert guidance on how and when to make the most efficient use of the exercises
  • Assignments cross-referenced to The Child Psychotherapy Treatment Planner, Fifth Edition—so you can quickly identify the right exercises for a given situation or problem
  • A CD-ROM contains all the exercises in a word-processing format—allowing you to customize them to suit your and your clients’ unique styles and needs

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Essential Dental Therapeutics (Essentials (Dentistry)) 1st Edition

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About the Author

Pediatric Colorectal and Pelvic Surgery: Case Studies 1st Edition

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This new handbook teaches and explains the key principles in the management of complex pediatric colorectal diagnoses. By using case-based presentations, radiographic images, operative images with Multiple Choice Questions to test knowledge, this book serves as an invaluable educational tool. ‘Learning Points’ are included and the text includes comprehensive explanatory chapters. The 60 cases included encompass the full range of pediatric conditions, and the additional learning material completes this unique handbook. The interactive e-book further, with additional video content, enhances the learning experience for all clinicians involved in the treatment of children suffering from colorectal disorders.

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Physical Therapy Clinical Handbook For Ptas 2nd Edition

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Physical Therapy Clinical Handbook for PTAs, Second Edition, is a concise and condensed clinical pocket guide designed specifically to help physical therapist assistants and physical therapist assistant students easily obtain helpful evidence-based information. This succinct, summarizing pocket-guide covers the evaluative as well as interventional aspect of physical therapy and offers immediate guidance concerning physical therapy data collection and interventions in various clinical settings including musculoskeletal, neurologic, cardiopulmonary, integumentary, geriatric, pediatric and acute care. With its portable and user-friendly format, this handbook is a valuable resource for physical therapist assistant students during the education training program and throughout clinical practice. The Second Edition features a new and unique look at physical therapy in acute care provided by PTAs. Acute care topics include musculoskeletal and neurological acute care, as well as the significant factors in acute care to consider while applying physical therapy to patients with endocrine, gastrointestinal, genitourinary, and oncological disorders/diseases. The Second Edition contains physical therapy terminology reflecting current physical therapy practice according to the APTA’s “Guide to Physical Therapist Practice” and also includes guidelines from the CDC and JCAHO. Appendices contain helpful balance assessment forms, and cardiac and integumentary patient education forms.

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Innate Antiviral Immunity: Methods and Protocols (Methods in Molecular Biology) 1st ed. 2017 Edition

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This book explores methods to study the complex and evolving interplay between a virus and its host that range from model systems to the detection of chemical molecules. The collection starts with the application of humanized mice and zebrafish as model organisms to study virus-host interactions and induction of innate immune responses. Subsequent chapters outline diverse methods to detect small interfering RNAs, microRNAs, and virus-derived dsRNA from a variety of cells, tissues, and organisms, as well as to interrogating the cytosolic RNA and DNA sensing pathways, including using RNA PAMPs as molecular tools, purification of cGAMP from virus particles and infected cells, and mechanisms to visualize the subcellular localization and activation of the adaptor proteins MAVS and STING. Cutting-edge methods, including high-throughput and genome-wide CRISPR/Cas9 screens, chromosome conformation capture, and whole-exome sequencing, are described to identify novel mediators, pathways, and variants underlying host susceptibility. Given the importance of studying these pathways and players under physiologic conditions, methods describing the isolation of primary mouse sensory neurons and group 2 innate lymphoid cells are also provided. Finally, this collection comes full circle back to the whole organism level and concludes with epidemiological methods to investigate virus-host interactions and the induction of innate immunity. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Innate Antiviral Immunity: Methods and Protocols spans a diverse array of approaches to study and elucidate the intricacies of this vital area of study.

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The Wills Eye Manual: Office and Emergency Room Diagnosis and Treatment of Eye Disease Seventh Edition

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Publisher’s Note:   Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product.

For more than 25 years, The Wills Eye Manual has been a best-selling source of authoritative guidance on treating ocular disorders in an office, emergency room, or hospital setting.  The 7th Edition introduces exciting new changes to bring this pocket-sized reference thoroughly up to date – including extensive multimedia content – while retaining the features that have made it so useful in daily practice.

New to this edition:

  • Recent major clinical trials data
  • Expertly produced videos depicting a wide range of common procedures with step-by-step narration, carefully selected to complement key techniques
  • Changing trends in trauma, oculoplastics, cornea, pediatrics, neuro-ophthalmology, uveitis, and more

Outstanding features you’ve come to expect from the Wills Eye Manual:

  • The most accurate and current information on more than 200 ophthalmic conditions
  • Effective clinical recommendations for evaluation, diagnosis, management, and treatment
  • Concise outline format for portability and quick reference
  • All chapters written and edited by the residents and attending ophthalmologists at one of busiest and largest eye hospitals in the country

It’s everything you wanted to know and nothing more.

Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:

  • Complete content with enhanced navigation
  • Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web
  • Cross-linked pages, references, and more for easy navigation
  • Highlighting tool for easier reference of key content throughout the text
  • Ability to take and share notes with friends and colleagues
  • Quick reference tabbing to save your favorite content for future use

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The Education of a Coroner: Lessons in Investigating Death

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In the vein of Dr. Judy Melinek’s Working Stiff, an account of the hair-raising and heartbreaking cases handled by the coroner of Marin County, California throughout his four decades on the job—from high-profile deaths to serial killers, to Golden Gate Bridge suicides.

Marin County, California is a study in contradictions. Its natural beauty attracts thousands of visitors every year, yet the county also is home to San Quentin Prison, one of the oldest and largest penitentiaries in the country. Marin ranks in the top one percent of counties nationwide in terms of affluence and overall health, yet it is far above the norm in drug overdoses and alcoholism, and comprises a large percentage of suicides from the Golden Gate Bridge.

Ken Holmes worked in the Marin County Coroner’s Office for thirty-six years, starting as a death investigator and ending as the three-term, elected coroner. As he grew into the job—which is different from what is depicted on television—Holmes learned a variety of skills, from finding hidden clues at death scenes, interviewing witnesses effectively, managing bystanders and reporters, preparing testimony for court to notifying families of a death with sensitivity and compassion. He also learned about different kinds of firearms, all types of drugs—prescription and illegal—and about certain unexpected and potentially fatal phenomena such as autoeroticism.

Complete with poignant anecdotes, The Education of a Coroner provides a firsthand and fascinating glimpse into the daily life of a public servant whose work is dark and mysterious yet necessary for society to function.

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Comprehensive Cleft Care: Family Edition Pap/Psc Edition

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For parents, learning that their newest family member may bring some unexpected challenges along with the blessing of his or her arrival can take a bit of adjustment. They have questions and need a trusted source of information to allay their fears. You are that source. However, most of the time, parents receive almost too much information to take in all at once, and questions arise as they digest the information. The parents of your patients may wonder: Did I hear that right? What does that term mean? What should I do next? What is in store for my family?

From diagnosis to treatment options, Comprehensive Cleft Care: A Family Edition provides families with important information to help them fully understand their child’s condition and its treatment. Authored by parents and professionals, this unique work was written with real-life challenges in mind. Two of the book’s editors have raised cleft-affected children. As a result, the information provided is not only informative and helpful, but also personal, readily accessible, and relevant from a parent’s perspective.

This book enables parents and families to play a central role in navigating their child’s care while working alongside the rest of the care team. Written in easy-to-read language, it contains over two dozen short chapters that mirror topics discussed in the corresponding text written for health care professionals, Comprehensive Cleft Care, Second Edition. Topics covered include the fundamentals of care, psychosocial and educational aspects, cleft lip and palate repair, speech and hearing, airway and breathing issues, dental and orthodontic principles, and more.

By providing up-to-date information in a clear and concise format, this book can help to educate parents and to alleviate much of the anxiety they have regarding their child’s condition and its treatment. Published with a complimentary eBook, this guide is an invaluable resource for families seeking to help their cleft-affected child reach his or her full potential.

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ASEP’s Exercise Medicine-Text for Exercise Physiologists

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Watching TV, surfing the Internet, and sitting for long hours have replaced more active pursuits. Millions of Americans are simply not moving enough to meet the minimum threshold for good health and longevity. Exercise physiologists have researched and highlighted this fact for decades. That is why they emphasize the importance of regular exercise in the prevention of chronic diseases associated with physical inactivity and a sedentary lifestyle. Heart disease, obesity, type 2 diabetes, high blood pressure, stroke, peripheral arterial disease, depression, several types of cancers, and osteoporosis can be treated or even prevented with properly prescribed exercise. There is a need for integrating exercise physiology knowledge and rehabilitation programs as a continuous part of the healthcare profession. This opens up the opportunity for new approaches to manage patients suffering from chronic diseases and disabilities. ASEP’s Exercise Medicine Text for Exercise Physiologists is designed to educate exercise physiologists about the significance of professionalism in exercise physiology, exercise medicine, and entrepreneurship opportunities. It combines scientific principles with cardiovascular calculation steps that support its use in the development of safe, well-rounded, and individualized exercise programs to help clients and patients sleep better, reduce stress, maintain a healthy body weight, keep bones strong and joints healthy, decrease the risk for colon cancer, and improve mental function. This textbook demonstrates the importance of exercise medicine, and will familiarize readers with ASEP guidelines. Exercise physiologists in training will, therefore, be prepared for contributing a meaningful role in the healthcare services sector.

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