This book provides discussions on bronchial asthma from a clinical perspective, focusing on the recent studies on its pathophysiology, diagnosis and treatment. It also explores the lastest findings regarding the phenotypes and endotypes of asthmatic patients, making it of particular interest to those involved with non-eosinophilic asthma and eosinophilic asthma. Further, it discusses the importance of ILC 2 in eosinophilic asthma, and the accumulated results from the forced oscilliation technique and periostin that are actively practiced in Japan. As some aspects of diagnosis and treatment are different in Western and Asian countries, it is important that the data is disseminated around the globe.
The clinical questions addressed by the authors are critical and thought provoking, while the questions raised by the editors are instructive, informative and provide new perspectives on unresolved issues. This book appeals to wide readership from beginning learners to physicians in clinical practice and scholars engaging in basic research.
Sex Steroids’ Effects on Brain, Heart and Vessels Volume 6
This book analyzes the effects of estrogens and progesterone on brain cells, the immune system, neuro inflammation, myelin formation and steroid receptor distribution, as well as their clinical impacts.
It also explores the relationship between sex-steroid withdrawal and the development of brain symptoms such as hot flushes, sleep disorders, mood changes, depression and also cognitive disorders and dementia, as well as the effects of hormone menopause therapy on such symptoms and diseases.
Starting with obstetrical history and cardiovascular risk in later life, the second part of the book examines the effects of estrogens and progestogens on vascular tissues, atherosclerosis and coronary heart diseases, as well as the impact of hormone replacement therapies on cardiovascular risks and mortality.
This volume is a useful, clear and up-to-date tool for gynecologists, endocrinologists, neurologists and cardiologists, and serves as a valuable source of information for all physicians involved in women’s health.
Menstrual Cycle Related Disorders Volume 7
This volume discusses menstrual cycle related disorders, which are a major concern from adolescence to menopause.
Starting from hypothalamic pituitary gonadal axis regulation, it analyzes the characteristics and treatments of hypothalamic amenorrhea and eating disorders, as well as polycystic ovary and adolescent hyperandrogenism. It also examines the importance of body composition and physical performance. The book particularly focuses on the diagnosis of and therapies for hormone-related headaches, the management of trans sexuality in the gynecological outpatient area, dysfunctional uterine bleeding and premature ovarian insufficiency. Further, it analyzes the basic, clinical and therapeutic aspects of endometriosis, as well as the important opportunities that SPRMs (selective progesterone receptor modulators) offer in contraception and fibroid therapy.
This book is a useful tool for gynecologists, endocrinologists and general practitioners, and is a valuable resource for all physicians involved in women’s health.
Stroke Revisited: Diagnosis and Treatment of Ischemic Stroke
This book presents state of the art knowledge on stroke management in a unique organizational style. Ischemic stroke is extensively covered, with inclusion of overviews that dynamically describe all relevant diagnostic and therapeutic processes in a time sequence mirroring real practice. The individual components of management and key issues are fully discussed with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to retrieve fundamental information quickly. In addition, the book considers the various causes of stroke and provides detailed guidance on means of secondary prevention. The recent demonstration of the substantial benefit of intra-arterial thrombectomy using stentrievers in patients with acute ischemic stroke represents a great moment in the history of stroke management. As we embark on a new era, there is an urgent need to review and evaluate current modalities for stroke diagnosis and treatment. In tackling this task, this book will be invaluable for physicians, angiographic interventionists, surgeons, and students seeking to acquire up-to-date knowledge on stroke.
Stroke Revisited: Hemorrhagic Stroke 1st ed
This book presents state of the art knowledge on hemorrhagic stroke in a unique organizational style. All aspects are covered, including risk factors, pathophysiology, diagnostic modalities, treatment, and prevention. Individual procedures and issues are fully discussed with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to retrieve fundamental information quickly. Furthermore, in an accompanying overview diagnostic and therapeutic processes are dynamically described in a time sequence mirroring real practice. The recent striking advances in brain imaging have resulted in a better understanding of the causes and pathophysiology of hemorrhagic stroke, and management has been enhanced by a variety of surgical techniques, intensive monitoring, and administration of novel medical treatment. Against this background, it is timely to summarize current understanding of hemorrhagic stroke and its management from a practical perspective. This textbook will be invaluable for stroke physicians, surgeons, and students seeking to acquire up-to-date knowledge on the subject.
Female Puberty: A Comprehensive Guide for Clinicians
Female Puberty: A Comprehensive Guide for Clinicians is a practical reference, covering the full range of issues related to pubertal development. Developed to answer pointed clinical questions and to provide a thorough review of the literature, the book covers both the basics and the complexities of puberty, encompassing psychosocial development to pubertal nuances in highly specialized populations. Comprehensive in scope, this title offers concepts that are concisely conveyed and chapters that complement each other well. Complex subjects such as details of the hypothalamic-pituitary-ovarian axis are covered in a readily understandable manner and bullet points throughout the text serve as helpful reminders to the reader. An invaluable contribution to the literature, Female Puberty: A Comprehensive Guide for Clinicians will be of great interest to all health providers concerned with female reproductive health – including obstetrician gynecologists, reproductive endocrine specialists, pediatricians, pediatric specialists, family practitioners and allied health professionals.
The first resource dedicated to providing concise summaries of the most clinically relevant inpatient care guideline summaries
CURRENT Practice Guidelines in Inpatient Medicine, 2018-2019 is written to spare busy physicians, nurse practitioners, physician assistants, and medical students from having to wade through full-length practice guidelines in order to provide high-quality care for hospitalized adults. With content drawn from reliable sources such as major professional societies and government agencies, each section of the book outlines the guidelines surrounding initial assessment, acute management, and subsequent care for conditions commonly encountered in the hospital setting.
This book summarizes the imaging characteristics and theory of CNS infections, serving as a clinical guidance and having a practical significance for the understanding, prevention and diagnosis of infectious neurology. It includes extensive CT, MRI images on gross anatomy, pathological tissue, immunohistochemistry, electronic speculum, etc. It is divided into 19 chapters according to infectious types.
On the basis of imaging diagnosis, through the cross research of imaging with autopsy and pathology, the imaging characteristics and evolution was revealed. This book will be a valuable reference on the clinical practice and research of neuroinfections.
Bone Health: A Reflection of the Social Mosaic 1st ed
This multidisciplinary book addresses three lines of evidence (medieval, contemporary, and epigenetic) regarding the effect of human socio-economic status on bone health. It provides an overview of the extent to which human social background affects adult bone quality and quantity, and makes recommendations for future skeletal biology research into lifestyle-related musculoskeletal disorders.
The book is divided into three major parts, the first of which discusses bone and dental health in medieval human skeletal remains from distinct socio-economic status groups. In turn, Part 2 reviews bone health in contemporary human populations with a range of social backgrounds; in addition, a conceptual model proposing a social gradient of osteoporosis and fracture risk related to biological mechanisms and cumulative stressors throughout the human lifecycle is presented. Lastly, Part 3 highlights the role of epigenetics in socially patterned risk factors for skeletal disorders, and discusses how epigenetic mechanisms transduce the psychosocial environment and increase the risk of developing conditions such as osteoporosis.
Overall, the book highlights the importance of considering the social-biological nexus in future skeletal biology research and future treatment of bone disease. Increased awareness of this nexus can potentially improve individual and population-level bone health interventions, reducing the social inequities observed in fracture risk.
Given its scope, the book offers a valuable resource for researchers, academics, and students in the fields of medicine, epidemiology, the health sciences, biological anthropology, human anatomy and adaptation, developmental studies of human societies, human biology, and any field concerning musculoskeletal disorders and health. It will also benefit clinical practitioners evaluating osteoporosis, osteopenia, fracture risk, bone quality and quantity.
Surgery for Parkinson’s Disease 1st ed
Deep brain stimulation for the treatment of patients with Parkinson’s disease was introduced in the 1990s. Initially performed only at academic centers, over the past decade it has become a widespread surgical procedure. A variety of surgical techniques are employed and innovations are introduced frequently. This book is an ideal source of information for the many practicing neurosurgeons who did not learn this surgery during their training but would now like to add it to their practice, as well as an excellent update on exciting new developments in surgery for Parkinson’s disease.
This book is designed to provide practicing neurosurgeons with current knowledge on the practical aspects of surgical treatment of patients with Parkinson’s disease. It explains how to identify surgical candidates and determine the optimal surgery, describes the various surgical techniques that are currently employed, and offers insights into how to optimize deep brain stimulation therapy after implantation. The keys to avoidance of surgical complications are carefully elucidated. In addition, an overview is provided of potential advances on the near-term horizon, including closed-loop deep brain stimulation, gene therapy, and optogenetics. All topics are covered by experienced Parkinson’s disease surgeons, in a concise and digestable format.
The book will be an ideal source of information for the many practicing neurosurgeons who would like to add deep brain stimulation to their practice, as well as an excellent update on new developments in surgery for Parkinson’s disease.