Category: Respiratory Medicine

Pulmonary Manifestations of Rheumatic Disease, An Issue of Clinics in Chest Medicine

This issue brilliantly pairs a rheumatologist with a pulmonologist to explore each of the 14 article topics.  Topics include autoantibody testing, ultility of bronchoalveolar lavage in autoimmune disease, and pulmonary manifestations of such conditions as scleroderma, rheumatoid arthritis, lupus erythematosus, Sjogren’s Syndrome, Inflammatory Myopathies, and Relapsing Polychondritis.  The pulmonary vasculitities are discussed, as is antiphospholipid antibody syndrome, ankylosing spondylitis, and the impact of osteoporosis on pulmonary fuction.  Toxicity and monitoring of immunosuppressive therapy used in systemic autoimmune diseases is reviewed, as is lung transplantation in autoimmune diseases.

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Reproductive Medicine for Clinical Practice: Medical and Surgical Aspects

This first volume of the series of the International Academy of Human Reproduction focuses on new aspects of reproductive medicine, from the professional responsibility model of ethics to the areas of high clinical involvement in human reproduction, such as endometriosis, polycystic ovary, family planning and post-coital contraception. The book discusses fertility and assisted reproductive techniques in the context of genetics and epigenetics as well as psychosomatic and longevity aspects. In addition, it presents new technologies and therapeutic strategies to improve IVF results and prevent ovarian hyperstimulation syndrome, as well the new challenges and the future of imaging in reproduction. Menopause and the effects of estrogens on atero-prevention, mood, and more generally the reproductive hormones impact on dementia and healthy aging are also covered. Further, it includes a section devoted to innovative aspects of gynecological surgery, discussing the treatments of vaginal aplasia, reproductive microsurgery and technological breakthroughs in pelvic organ prolapse surgery. Last, but not least, it examines the syndromic aspects of preterm birth.

This volume is a useful and comprehensive tool for gynecologists, obstetricians, endocrinologists  and all specialists who deal with women’s reproductive health.

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The Mediastinal Mass: A Multidisciplinary Approach

Tumors of the mediastinum are usually diagnosed in young patients, but they can develop at any age and form any tissue that exists in or passes through the chest cavity. The diagnosis and the accurate assessment of the mediastinum masses represents a challenge, given their clinical variability from asymptomatic to producing symptoms of cough, chest pain, and dyspnea. Mediastinal tumors encompass a wide range of various neoplasms. The localization of mediastinal masses is critical in the diagnosis: the anterior mediastinal masses are generally thymomas, teratomas, substernal thyroid/parathyroid tissue, or lymphomas; the middle mediastinum massess are typically pericardial and bronchogenic cysts; the posterior mediastinum  masses are often neurogenic tumors and esophageal cysts. The wide variety of different entities demonstrates a heterogeneous spectrum of clinical and pathologic features, suggesting that a uniform “standard” management of these patients is not appropriate.
In this context, the proposed book will provide a comprehensive review of the mediastinal tumors according to different sites of the diseases, including the masses of anterior, middle and posterior mediastinum. The handling of these tumors requires a multidisciplinary approach due to the complex anatomy of the mediastinum as well as the different clinical, radiographic, and prognostic features. This book has risen from the desire to provide to the specialists in the field an easy, updated and practical guidelines title to facilitate the clinical practice of mediastinic masses. This book will be a comprehensive guide to clinical best practices developed through the opinions of experts in the field.

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Since the cloning of the cystic fibrosis transmembrane conductance re- lator (CFTR) nearly a decade ago, cystic fibrosis (CF) research has witnessed a dramatic expansion into new scientific areas. Basic researchers, clinicians, and patients increasingly rely on fundamental techniques of genetics, molecular biology, electrophysiology, biochemistry, cell biology, microbiology, and immunology to understand the molecular basis of this complex disease. Research into the pathophysiology of CF has established numerous paradigms of ion channel dysfunction that extend from inflammation and infection in the airways of patients to basic mechanisms of protein processing and regulation in intracellular components. With these rapid advances has come an increasing need for research scientists to understand and utilize a growing array of basic laboratory tools. This volume of Methods in Molecular Medicine, Cystic Fibrosis Methods and Protocols satisfies that need by providing detailed protocols for the laboratory techniques used throughout CF research. From electrophysiology and cell biology, to animal models and gene therapy, the comprehensive set of methods covered here provide step-by-step instructions needed for investigators to incorporate new approaches into their research programs. Contributions have been chosen to reflect the rich diversity of techniques and to provide a cohesive framework for understanding challenges that are currently at the forefront of CF research. It is hoped that this volume will serve as a valuable reference that will not only foster interdisciplinary investigations into current problems encountered in CF, but also facilitate the translation of new scientific discoveries into clinical solutions.

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Advances in Pulmonary Medicine: Research and Innovations

This book discusses a wide range of investigations and practice-oriented advances in pulmonary medicine and critical care.

Pulmonary diseases are a major cause of hospitalization and mortality, affecting millions of people worldwide. Addressing a range of topics, including chronic obstructive pulmonary disease, sleep apnea, and lung cancer, the book offers insights into the disease mechanisms and risk factors, along with practical aspects concerning the maintenance of quality of life, adherence to therapy, and palliative treatment and care. Further, it explores diagnostic and treatment approaches to respiratory dysfunction and respiratory failure, highlighting the beneficial effects of good sleep quality in chronic pulmonary conditions and lung transplant patients. The book also presents novel experimental research on the cellular voltage-gated sodium channels in the mechanism of pathological cough, which is particularly relevant for future targeted antitussive therapy. Lastly, it addresses the epidemiological aspects of pulmonary infections.

As such, this book is a valuable resource for medical scholars, clinicians, family physicians, and other professionals seeking to improve the management of respiratory diseases.

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Entry Level Exam Review for Respiratory 2nd Edition

This examination review book provides a personalized study plan for candidates preparing for the National Board for Respiratory Care (NBRC) Entry-Level Examination. It presents an exhaustive review of the test matrix, including over 850 questions and analyses based on the 1998 NBRC Entry-Level Examination Matrix. A chapter on test-taking strategies is designed to build self-confidence, discusses when and how to guess, and explains how to think “the NBRC way.” Each question contains a keyed answer, detailed analysis about the question, and a list of references for further study. Detailed scoring forms are available throughout the book to assist candidates in evaluating strengths and weaknesses, and for assessing progress while working through the book. Each question is also linked to a specific examination matrix item allowing candidates to become familiar with the test matrix. A timetable is also included to help the candidates organize the time and activities.

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HRCT in Interstitial Lung Disease: Instructive Case Studies 1st ed

With the aid of a series of instructive case studies, this book presents the characteristic high-resolution computed tomography (HRCT) findings seen in the group of disorders referred to as interstitial lung disease. The first, introductory part of the book explains the role of the multidisciplinary team in diagnosis and differential diagnosis and discusses basic pulmonary differential diagnosis, radiologic anatomy, and HRCT patterns. The second part is organized according to the four dominant types of HRCT pattern encountered in interstitial lung disease: low attenuation, linear opacities, nodular, and high attenuation. Within this classification, each disorder is introduced using a specific case, with detailed information on patient history, course of the illness, and laboratory and pulmonary function tests. HRCT findings are then presented, together with reflections of the multidisciplinary team, comprising a radiologist, a pulmonologist, and a pathologist. At the end of each case, comments are made on differential diagnosis, highlighting the role of HRCT. The book will be of high value for radiologists and pulmonologists at all levels of experience.

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Interventions in Pulmonary Medicine 2nd ed

This new edition offers comprehensive coverage of all areas of interventional pulmonology, a minimally invasive endoscopic method for diagnosing and treating lung disorders. The text is divided into eight sections on the major areas of interventional pulmonology, including basic endoscopy, lung cancer staging, and interventional bronschoscopy in asthma and emphysema. Chapters then explore specific procedures and techniques, including medical thoracoscopy, flexible and rigid bronchoscopy, endobronchial ultrasound, and electromagnetical navigation with coverage of history, indications and contraindications, and up-to-date evidence-based reviews. In recent years there have been many advances in interventional pulmonology, the most significant relating to lung cancer early diagnosis and late-stage treatment. Two new chapters on lung cancer epidemiologic changes and personalized lung cancer treatment explore new methods for maximizing patient care for an increasingly prevalent disease. This inclusive volume concludes with a look towards the future of interventional pulmonology and experimental techniques currently being tested. Interventions in Pulmonary Medicine, Second Edition, is a must have for pulmonologists, endoscopists, pulmonary oncologists, ENT physicians, thoracic surgeons, anesthesiologists, and intensive care specialists and their teams.

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