Comprehensive Toxicology 3rd Edition

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Comprehensive Toxicology 3rd Edition

Comprehensive Toxicology, Third Edition, discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation.

Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies.

Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology.

  • Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems
  • Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system
  • Features additional coverage throughout and a new volume on toxicology of the hematopoietic system
  • Presents in-depth, comprehensive coverage from an international author base of domain experts

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Oxford Desk Reference: Toxicology (Oxford Desk Reference Series) 1st Edition

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Oxford Desk Reference: Toxicology (Oxford Desk Reference Series) 1st Edition

Overdose and poisoning are one of the most frequent acute medical presentations seen in emergency departments, and high dependency and intensive care facilities. The Oxford Desk Reference: Toxicologyprovides an authoritative guide for the management of patients with poisoning. Each chapter includes key clinical features and potential treatment options to help physicians to assess the potential severity of the poisoned patient and provide the optimum clinical care.

A reader-friendly layout ensures that information is easy to find and assimilate, and topics are self-contained to aid quick diagnosis. Presented in an easy-to-use double-page spread format, highly bulleted and concise, the Oxford Desk Reference: Toxicology is ideal for quick referral when an acute problem arises.

Contributions from the leading figures in toxicology make this book indispensable for all those involved with the management of poisoned patients, especially trainees and consultants working in emergency medicine, acute medicine, and critical care.

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Metal Allergy: From Dermatitis to Implant and Device Failure 1st ed. 2018 Edition

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This volume has been compiled in response to the ongoing revolution in our understanding of metal contact allergy, and the ensuing challenge this has created for clinicians and others to synthesize large amounts of sometimes contradictory data. It opens by providing a comprehensive overview of the use and regulation of metals in our society, metal properties, and available testing methodologies. Common and uncommon metal allergens and sources of exposure are then reviewed in depth, and detailed sections are devoted to hypersensitivity to metal implants (which may be associated with device failure and/or dermatitis), metal allergy in select patient populations, and less frequently encountered manifestations of metal allergy.

The prevalence of metal allergy in the general population is high: up to 17% of people are allergic to nickel, and 1–3% to cobalt and chromium. Environmental sources of metal exposure include jewelry, clothing, electronic devices, coins, leather, diet, and occupational exposure. As metals are ubiquitous, this book will be an indispensable reference text for a wide range of clinicians and investigators, meeting the needs of all who are interested in metal allergy and its diagnosis and management.

Basic and Clinical Toxicology of Organophosphorus Compounds

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This book explains the chemistry of Organophosphorus compounds (OPs), their mechanism of toxicity and the history of OPs from their initial discovery to the development of new compounds such as Novichoks. It details the harmful effects to human health both as a result of acute and chronic OP exposure and the necessary clinical management of affected patients to reduce their toxic side effects. The book also explains the detrimental effect that OPs have had on the environment and the efforts being made to prevent this in the future. Finally, the book looks at the incidents where OPs have been used as chemical warfare agents. Basic and Clinical Toxicology of Organophosphorus Compounds aims to act as a comprehensive guide to all aspects of OPs and is a key resource for clinical toxicologists and related health professionals involved in the prevention, diagnosis and clinical management of OP patients, toxicologists and other scientists involved in research on OPs including regulatory issues and postgraduate students in Toxicology and related fields.

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Toxicology and Risk Assessment: A Comprehensive Introduction 2e 2nd Edition

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Provides a complete understanding of how our bodies respond to toxicants, and the principles used to assess the health risks of specific exposure scenarios

Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition reflects recent advances in science and technology, and provides the scientific background and methodological issues to enable the reader to understand the basic principles in toxicology and to evaluate the health risks of specific exposure scenarios.

Completely updated with the latest information, this book offers a concise introduction to the subject. It is divided into five sections: Principles in Toxicology, Organ Toxicology, Methods in Toxicology, Regulatory Toxicology, and Specific Toxicity. The 2nd Edition adds new chapters that cover recent scientific and technological advances and current topics including the endocrine system, alternatives to animal testing, risk assessment and thresholds for carcinogens, European and international regulation, nanomaterials, fuels, fragrances, and agrochemicals.

  • Concentrates on the basic concepts of toxicology and provides sufficient information for the reader to become familiar with them in order to understand the principles and to evaluate the risks at given exposures
  • 30% new chapters cover recent scientific and technological advances including alternatives to animal testing; genotoxic carcinogens; REACH regulations; nanomaterials; fuels; fragrances; PAHs; and agrochemicals
  • Written by a team of international specialists, and edited by two outstanding scientists in the field

Fully updated and expanded, Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition is an essential text for any student or researcher with an interest in toxicology and related risk assessments.

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Botulinum Toxin Treatment in Clinical Medicine: A Disease-Oriented Approach 1st ed. 2018 Edition

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About the Author

Clarke’s Analysis of Drugs and Poisons, 4th Edition (Book + 1-Year Online Access Package) 4 Revised Edition

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Clarke’s Analysis of Drugs and Poisons, 4th Edition is now being offered solely as a print and online package. It is a full book & digital package, consisting of the two volume reference book in a slip case, plus one year’s individual access to the online version of Clarke’s via MedicinesComplete, with all the attendant benefits, including updating annually.

(A secure code will be included in the package enabling the end-user to access MedicinesComplete and setup their account and their 1-Year subscription)

MedicinesComplete is produced and updated by Pharmaceutical Press.

Clarke’s Analysis of Drugs and Poisons is the definitive source of analytical data for drugs and poisons. Written by over 40 international experts, the resource also boasts an editorial advisory board of over 45 world renowned scientists.

This reference work has been completely revised and updated for the new edition, and comprises two volumes.

The book is essential for all forensic and clinical toxicologists, pathologists, hospital pharmacists, pharmaceutical analysts, clinical pharmacologists, clinical and forensic laboratories, and poison information centers.

From the reviews of the previous edition

‘Some things in life are worth the wait and truly this 3rd edition of Clarke’s Analysis of Drugs and Poisons falls into this category…the quality is superb’ Australian Journal of Forensic Sciences

‘Clarke has gained an international reputation as a reliable source of information for the analyses of drugs, and this new highly-expanded edition is the 21st century’s successor.’ Veterinary and Human Toxicology

‘The content is comprehensive, absorbing and layout is well planned and executed. Without doubt, this volume will be a much well thumbed institution in any serious analytical laboratory and will assist generations of scientists in years to come.’ Pharmacy Education

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Pesticide Toxicology and International Regulation (Current Toxicology) 1st Edition

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This book brings together key features of the toxicology and occupational hazards of pesticides and the way their use is regulated in the main trading regions of the world. There are chapters on each of the main groups of insecticides, namely organochlorines, anticholinesterases and pyrethrins and pyrethroids. The book also covers fungicides and herbicides, as well as more specialised agents such as microbial pesticides. The risks and hazards to humans are considered, both occupational and through the consumption of contaminated foodstuffs.  Additionally, clinical aspects of pesticide poisoning are discussed.

The possibility of harm from pesticide exposure has led to the development of national and international regulations governing the application of pesticides. The book describes the regulatory systems in three major economic areas: the North American Free Trade Area (USA, Canada and Mexico), the European Union and Japan.

This book should be of interest to all individuals working on the development and application of pesticides anywhere in the world. All those involved in the manufacture, regulation and toxicology of pesticides should also benefit from reading this book.

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Alternatives for Dermal Toxicity Testing 1st ed

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About the Author

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