Chemotherapy and Immunotherapy in Urologic Oncology

Chemotherapy and Immunotherapy in Urologic Oncology: A Guide for the Advanced Practice Provider

Chemotherapy and Immunotherapy in Urologic Oncology

This book is designed to familiarize clinical practitioners in systemic therapy options and medical management of urologic malignancies including prostate cancer, bladder and upper tract urothelial carcinoma, and renal cell carcinoma. Organized by organ system, the text highlights new therapies such as novel forms of androgen deprivation, cytotoxic chemotherapy, immune check point and immunomodulatory agents, and targeted therapies. Written by experts in the field, the book also reviews current chemotherapy and immunotherapy regimens for genitourinary malignancies and discusses indications, outcomes, and toxicities, as well as clinical trial concepts. Each of the book’s chapters offers a bulleted box of clinical pearls on the particular role of the APP.
Chemotherapy and Immunotherapy in Urologic Oncology: A Guide for the Advanced Practice Provider is a resource for urologists, uro-radiologists, medical clinicians and family practitioners alike, familiarizing its audiences with systemic therapy regimens for urologic malignancies, as well as their expected outcomes and side effects.

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Precision Medicine in Radiation Oncology

Precision Medicine in Radiation Oncology

Precision Medicine in Radiation Oncology

 

Precision medicine takes into account each patient’s specific characteristics and requirements to arrive at treatment plans that are optimized towards the best possible outcome. As the field of oncology continues to advance, this tailored approach is becoming more and more prevalent, channelling data on genomics, proteomics, metabolomics and other areas into new and innovative methods of practice. Precision Medicine in Oncology draws together the essential research driving the field forward, providing oncology clinicians and trainees alike with an illuminating overview of the technology and thinking behind the breakthroughs currently being made.

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Topics covered include:

  • Biologically-guided radiation therapy
  • Informatics for precision medicine
  • Molecular imaging
  • Biomarkers for treatment assessment
  • Big data
  • Nanoplatforms

Casting a spotlight on this emerging knowledge base and its impact upon the management of tumors, Precision Medicine in Oncology opens up new possibilities and ways of working – not only for oncologists, but also for molecular biologists, radiologists, medical geneticists, and others.

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Oral Cancer: Evaluation, Therapy, and Rehabilitation

Oral Cancer: Evaluation, Therapy, and Rehabilitation

Oral Cancer: Evaluation, Therapy, and Rehabilitation

Oral Cancer: Evaluation, Therapy, and Rehabilitation edited by prominent Johns Hopkins clinicians and educators Carole Fakhry, Karen Pitman, Ana Kiess, and David Eisele provides a comprehensive, state-of-the-art review on the diagnosis and management of oral cancer. This unique resource fills a void in the literature by exploring surgical and reconstructive issues specific to each subsite of the oral cavity. Important pre- and post-treatment evaluations by dental, speech language pathology, and the oncologic care team are reviewed.

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The comprehensive book is divided into 10 sections, each focused on different facets of the patients’ trajectory. The text starts with epidemiology of oral cavity cancer and discussion of patient populations at increased risk of oral cavity cancer. The book details pre-cancers, multidisciplinary diagnostic evaluations, treatment, post-treatment, recurrent and metastatic oral cancer, and palliative care, concluding with future directions such as chemoprevention. A full spectrum of oral neoplasms are covered in depth, including different types of squamous cell cancer, primary malignancies of the mandible, and sublingual and minor salivary gland malignancies.

Key Features

  • All oral cavity subsites are approached from both an ablative and reconstructive standpoint, with dedicated chapters focused on specific oral cancer reconstructive techniques
  • Discussion of oncologic considerations encompassing radiation and medical oncology including definitive radiation therapy, brachytherapy, adjuvant radiation therapy, and adjuvant chemotherapy/novel therapeutics
  • Clinical pearls cover complications of both surgery and radiation therapy, as well as psychological and dental implications of therapy
  • High-quality illustrations, photographs, and videos further elucidate impacted anatomy and techniques

Residents and clinicians in otolaryngology-head and neck surgery, oral and maxillofacial surgery, head and neck reconstructive surgery, medical oncology, and radiation oncology will benefit from reading this excellent resource. Dentists who wish to further their knowledge about oral cancers will also find it an invaluable reference.

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Lung Cancer Screening 1st Edition

Lung Cancer Screening 1st Edition

Lung Cancer Screening 1st Edition

Lung cancer is the leading cause of cancer-related death among men and women in the U.S. and worldwide. For many decades, lung cancer was the sole cancer among the deadly four without an evidence-based screening method for decreasing mortality. This changed in November 2011, when findings from the National Lung Cancer Screening Trial showed low-dose lung CT screening was more efficacious in reducing deaths in high-risk individuals than conventional radiography. As such, an ever-increasing number of health organizations now recommend this screening protocol.

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Lung Cancer Screening by Mark Parker and esteemed VCU Health colleagues, fulfills the dire need for a comprehensive guide explaining the crucial aspects of lung cancer screenings. The first two chapters lay a foundation with discussion of lung cancer epidemiology and risk factors beyond cigarette smoking. Subsequent chapters cover the fundamentals, with clinical pearls on setting up a successful lung cancer screening program, patient eligibility criteria, imaging variances of tumors in the lungs, screening pros and cons, and interpreting/reporting screening results.

  • The evolution and future of lung cancer screenings
  • Detection and management of unexpected incidental pulmonary and non-pulmonary findings
  • Discussion of test cases utilizing the Lung-RADSTM risk-stratifying system for low-dose chest CT screenings
  • Benefits and potential harms associated with mass lung cancer screening programs including false positive, false negative, and over-diagnosis rates

This state-of-the-art guide is essential reading for radiologists, oncologists, pulmonologists, and internists. It is a must-have bookshelf reference for hospital radiology and oncology departments, in particular for those setting up new lung cancer screening programs.

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Textbook of Clinical Trials in Oncology: A Statistical Perspective

Textbook of Clinical Trials in Oncology: A Statistical Perspective

Textbook of Clinical Trials in Oncology: A Statistical Perspective

There is an increasing need for educational resources for statisticians and investigators. Reflecting this, the goal of this book is to provide readers with a sound foundation in the statistical design, conduct, and analysis of clinical trials. Furthermore, it is intended as a guide for statisticians and investigators with minimal clinical trial experience who are interested in pursuing a career in this area.

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The advancement in genetic and molecular technologies have revolutionized drug development. In recent years, clinical trials have become increasingly sophisticated as they incorporate genomic studies, and efficient designs (such as basket and umbrella trials) have permeated the field. This book offers the requisite background and expert guidance for the innovative statistical design and analysis of clinical trials in oncology.

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Imaging in Clinical Oncology 2nd ed

Imaging in Clinical Oncology 2nd ed

Imaging in Clinical Oncology 2nd ed

This is the second edition of a well-received book reflecting the state of the art in oncologic imaging research and promoting mutual understanding and collaboration between radiologists and clinical oncologists. It presents all currently available imaging modalities and covers a broad spectrum of oncologic diseases for most organ systems.
Today, oncologic imaging faces the challenge of improving and refining concepts for precise tumor delineation and biologic/functional tumor characterization, as well as for purposes of creating individual treatment plans. The concept of radiomics has further advanced the conversion of images into mineable data and subsequent analysis of said data for decision-making support.

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Since the release of the book’s first edition, radiomics has been introduced in oncology studies and can be performed with tomographic images from CT, MRI and PET/CT studies. The combination of radiomic data with genomic features is known as radiogenomics, and can potentially offer additional decision-making support.
This book will be of interest to clinical oncologists with regard to the diagnosis, staging, treatment and follow-up on various tumors affecting the CNS, chest, abdomen, urogenital and musculoskeletal systems.

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The Basics of Cancer Immunotherapy

The Basics of Cancer Immunotherapy

The Basics of Cancer Immunotherapy

This book provides patients and their physicians (especially “non-oncologist” health care providers) with a clear and concise introduction to cancer immunotherapy, which, unlike traditional forms of cancer therapy, acts by boosting the patient’s own immune system to fight cancer. The unique features of cancer immunotherapy make its management, monitoring and side-effects different from those of traditional cancer therapy. Especially novel are the side effects of cancer immunotherapy, necessitating greater awareness for both patients and physicians in order to minimize complications of therapy.

The patient-friendly, concise, easy-to-understand, and up-to-date knowledge presented in this book will inform patients about the benefits and risks of cancer immunotherapy, and help them and their care providers to understand how immunotherapy would control their unique disease.   Researchers and academic professionals in the field of cancer immunotherapy will also find clear and useful information to help them communicate with patients or address unresolved problems.  Some key features of the book are:

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Encyclopedia of Cancer 3rd Edition

Encyclopedia of Cancer 3rd Edition

Encyclopedia of Cancer 3rd Edition

Encyclopedia of Cancer, Third Edition provides a comprehensive, up-to-date overview of the multiple facets of the disease, including research, treatment and societal impact. This new edition comprises 180 contributions from renown experts who present the latest in Mechanisms, Hallmarks of Cancer, Causes of Cancer, Prevention and Control, Diagnosis and Therapy, Pathology and the Genetics of specific Cancers. Readers will find a comprehensive overview of the main areas of oncology, including etiology, mechanisms, prevention, and treatments, from basic science to clinical applications and public health, all set alongside the latest advances and hot topics that have emerged since the previous edition.

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Topics of interest in the field, including genomics and epigenomics, our understanding of the causes of cancer and the approaches to preventing it (e.g., HPV vaccination, role of obesity and nutrition, molecular markers of environmental exposures), new screening techniques (e.g., low-dose CT for lung cancer) and improvements in the treatment of many cancers (e.g., breast cancer, lung adenocarcinoma) are comprehensively and authoritatively presented.

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Encyclopedia of Cancer 4th ed

Encyclopedia of Cancer 4th ed

Encyclopedia of Cancer 4th ed

This work comprehensively describes etiological factors in the development , Progression and metastasis of human cancers, both for hematological malignancies and for solid Tumors. Approaches for the diagnosis as well as for therapies are outlined too. The fourth edition of the “Encyclopedia of Cancer” features a vastly extended number of terms as compared to the previous edition. Previously published entries have enjoyed a vigorous updating and adjustment to current status of knowledge, a large number of new timely entries have been added to consider the amazing progress and modern developments both in basic and clinical aspects of cancer.

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Up-to date and authoritative Essays present a comprehensive picture of topics ranging from pathology,  to clinical oncology, and targeted therapy for personalized cancer medicine for major human cancers, in particular breast cancer, colorectal cancer, prostate cancer, renal cancer lung cancer and hematological malignancies , leukemias and lymphomas. Each author is an international authority for the particular topic, and each entry has been adjusted to an easy-to-follow reader-friendly structure that allows to collect very rapidly essential information. At the same time, these essays should be considered a starting point from which the quest for more detailed information can depart. Extensive cross referencing of essays is an instrument by which the acquisition of the complete picture of a particular topic will be facilitated.

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Liver Cancers: From Mechanisms to Management

Liver Cancers: From Mechanisms to Management

Liver Cancers: From Mechanisms to Management

This book explores in detail the primary liver cancers of hepatocellular carcinoma and cholangiocarcinoma examining the pathogenesis of disease along with diagnosis and current management options together with exploration of future treatment strategies and areas of controversy.   Furthermore, the book highlights management of the common secondary malignancies and touches on benign liver tumours and how to best manage these.

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Written in a clear and didactic style, this volume includes summaries of the key learning points and questions so that the reader can gauge their knowledge and understanding.

This book is aimed to broaden the knowledge base of primary care physicians, general physicians along with specialists in hepatology, oncology and hepato-biliary surgery

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