The Internist’s Guide to Minimally Invasive Gastrointestinal Surgery (Clinical Gastroenterology) 1st ed

The Internist’s Guide to Minimally Invasive Gastrointestinal Surgery (Clinical Gastroenterology) 1st ed

This book provides a concise yet comprehensive overview of minimally invasive gastrointestinal surgery, specifically for the medical internist. Organized by organ system, the text reviews the pathophysiology, workup, treatment, and surgical options for diseases inherent to gastrointestinal surgery. The book also focuses on when and who to refer to for consultation by a minimally invasive surgeon, as well as what to expect in the immediate and long term post-operative period.
Written by experts in the field, The Internist’s Guide to Minimally Invasive Gastrointestinal Surgery is a valuable resource for medical internists on minimally invasive GI surgery and how best to care for these patients in the pre and post-operative setting.

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Fundamentals of Anorectal Surgery 3rd ed

Fundamentals of Anorectal Surgery 3rd ed

This book is a comprehensive and current guide to the diagnosis and treatment of the entire spectrum of anorectal diseases. It focuses mainly on anorectal problems, as anorectal pathology is often more complex and challenging for surgeons than colonic diseases.

The book covers anorectal anatomy, physiology, and embryology as a foundation to a detailed description of preoperative, intraoperative, and post-operative patient management. All surgical procedures are shown in step-by-step detail by leading surgeons and gastroenterologists.

This book will be relevant to general, colon, and rectal surgeons in training and practice, gastroenterologists, and other practitioners with an interest in anorectal diseases.

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Textbook of Gastroenterology, 2 Volume Set 5th Edition

Textbook of Gastroenterology, 2 Volume Set 5th Edition

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Over the past twenty years, thousands of physicians have come to depend on Yamada’s Textbook of Gastroenterology. Its encyclopaedic discussion of the basic science underlying gastrointestinal and liver diseases as well as the many diagnostic and therapeutic modalities available to the patients who suffer from them was—and still is—beyond compare. This new edition provides the latest information on current and projected uses of major technologies in the field and a new section on diseases of the liver. Plus, it comes with a fully searchable CD ROM of the entire content.

Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease: A Focus on Early Phase Clinical Drug Development 2nd

Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease: A Focus on Early Phase Clinical Drug Development 2nd

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This book aims to aid the selection of the most appropriate methods for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, non-alcoholic fatty liver disease (NAFLD) and related cardiometabolic disorders.

Clinical research methods to assess the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycemic clamp technique, have become well-established in proof-of-mechanism studies.  However, selection of the most appropriate techniques is by no means straightforward. Moreover, the application of such methods must conform to the regulatory requirements for new drugs.

This book discusses the need for new pharmacotherapies for diabetes, obesity and NAFLD and the molecular targets of drugs currently in development.  Emerging technologies including functional imaging, circulating biomarkers and omics are considered together with practical and ethical issues pertaining to early phase clinical trials in subjects with cardiometabolic disorders.

Translational Research Methods in Diabetes, Obesity, and Non-Alcoholic Fatty Liver Disease is of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.

Hepatitis B and D Protocols: Volume 2: Immunology, Model Systems, and Clinical Studies

Hepatitis B and D Protocols: Volume 2: Immunology, Model Systems, and Clinical Studies

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Despite the availability of an effective vaccine, there are still 400 million people, worldwide who are chronically infected with hepatitis B virus (HBV). For them, the vaccine, as currently applied, has no value. Given the possible consequences of HBV infection, the number of those chronically infected with HBV presents an enormous public health challenge. For example, the major etiology of hepatocellular carcinoma (HCC) is chronic infection with HBV. Although fifth in cancer incidence, worldwide, HCC/liver cancer is the third leading cause of cancer death. The high mortality as- ciated with HCC arises because the disease is often detected late and is unresponsive to treatment. The number of deaths caused by PHCC is expected to rise over the next 20 years. Those chronically infected with HBV have a life risk of death to HCC of between 10 and 25%. Even the limited efficacy of drugs for the treatment of chronic HBV helps underscore the point that this disease is responsive to therapy. Drugs that target the polymerase (e. g. , hepsera and lamivudine) and interferon alpha represent two distinct strategies and show that both conventional antiviral and immunothe- peutic approaches can be used in management. However, the current inventory of therapeutics is inadequate. Interferon alpha is of limited value, only parenterally ava- able, and fraught with adverse reactions.

Hepatitis B and D Protocols: Volume 1: Detection, Genotypes, and Characterization

Hepatitis B and D Protocols: Volume 1: Detection, Genotypes, and Characterization

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Despite the availability of an effective vaccine, there are still 400 million people, worldwide who are chronically infected with hepatitis B virus (HBV). For them, the vaccine, as currently applied, has no value. Given the possible consequences of HBV infection, the number of those chronically infected with HBV presents an enormous public health challenge. For example, the major etiology of hepatocellular carcinoma (HCC) is chronic infection with HBV. Although fifth in cancer incidence, worldwide, HCC/liver cancer is the third leading cause of cancer death. The high mortality as- ciated with HCC arises because the disease is often detected late and is unresponsive to treatment. The number of deaths caused by PHCC is expected to rise over the next 20 years. Those chronically infected with HBV have a life risk of death to HCC of between 10 and 25%. Even the limited efficacy of drugs for the treatment of chronic HBV helps underscore the point that this disease is responsive to therapy. Drugs that target the polymerase (e. g. , hepsera and lamivudine) and interferon alpha represent two distinct strategies and show that both conventional antiviral and immunothe- peutic approaches can be used in management. However, the current inventory of therapeutics is inadequate. Interferon alpha is of limited value, only parenterally ava- able, and fraught with adverse reactions.

50 Gastrointestinal Cases & Associated Imaging

50 Gastrointestinal Cases & Associated Imaging

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Medical students and junior doctors are an integral part of the healthcare system. On an academic gastroenterology service, they often initially evaluate the patients that are then staffed by the consulting physician. Like all clinical specialties, the acquisition of medical knowledge is required to gain expertise. There are several resources such as textbooks and evidence-based articles that are …

Essential Medical Disorders of the Stomach and Small Intestine: A Clinical Casebook 1st ed

Essential Medical Disorders of the Stomach and Small Intestine: A Clinical Casebook 1st ed

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This casebook provides a concise yet comprehensive state-of-the art review of common stomach and small intestine disorders. The casebook is divided into five parts, each of which focuses on a major disorder, symptom, or clinical scenario related to the stomach and small intestine, including dyspepsia, small bowel disorders, nausea and vomiting, chronic abdominal pain, and post-operative GI surgery challenges. Each part is comprised of cases illustrating different aspects of the subject, with each case containing sections on case presentation, objectives, epidemiology and etiology, diagnostic evaluation and treatment, case follow-up, clinical pearls, and Q&A. Some major topics presented in these cases include nausea and vomiting in the pregnant patient, gas-bloat, functional abdominal pain, post-GI surgery complications, and celiac disease and non-celiac gluten sensitivity.
Written by internationally renowned experts in the field, Essential Medical Disorders of the Stomach and Small Intestine: A Clinical Casebook is a valuable resource for clinicians and practitioners who treat patients afflicted with disorders of the stomach and small intestine.

Evidence-based Gastroenterology and Hepatology (Evidence-Based Medicine) 4th Edition

Evidence-based Gastroenterology and Hepatology (Evidence-Based Medicine) 4th Edition

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The revised fourth edition of Evidence-Based Gastroenterology and Hepatology continues to provide the most current, evidence-based information for determining the appropriate medical and surgical options for screening for, diagnosing, and treating gastrointestinal conditions. With contributions from an international team of leading experts in the field, this edition includes practical recommendations for the care of individual patients based on the latest scientific evidence.

The text offers a unique resource that takes a completely evidence-based approach, and is designed to be an essential tool for gastroenterologists at all levels to consult frequently to improve the management of their time. Chapters review the clinical questions most often encountered by gastroenterologists in their daily practise. The text’s evidence (randomized controlled trials, systematic reviews or lower quality trials) and treatment recommendations are rated for quality using the respected GRADE framework. This newly revised edition:

  • Offers seven new chapters on the latest topics relevant to gastroenterology and hepatology
  • Provides a guide to patient management regimens that are supported by evidence
  • Includes a consistent rating of evidence quality using GRADE framework
  • Contains contributions from an acclaimed, international editorial team
  • Puts the focus on the most patient-important, clinical questions likely to be encountered

Written for gastroenterologists, hepatologists and specialty trainees in gastroenterology/hepatology, the revised edition of Evidence-Based Gastroenterology and Hepatology offers an evidence-based resource that appraises the evidence for the diagnostic tests and treatment regimens for gastrointestinal and hepatic diseases.

Diseases of the Liver and Biliary System in Children

Diseases of the Liver and Biliary System in Children

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An extremely practical text, this new edition of Diseases of the Liver and Biliary System in Children covers the essentials of paediatric hepatology. The range of material is wide and has been revised and updated to include the latest advances. Many helpful algorithms and tables are included and the references at the end of each chapter have been carefully selected so as to provide the most up-to-date information available. A concluding section comprising some 100 carefully annotated plates, completes this text.

Containing the contributions of 23 internationally acclaimed authorities, active both clinically and in research, the book provides an essential guide to the diagnosis and management of paediatric liver diseases, both common and uncommon for all those involved in the care of the child with liver disease. Diseases of the Liver and Biliary System in Children has become THE REFERENCE of choice for the paediatric gastroenterologist, hepatologist and surgeon.

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