Advanced Genetic Counseling: Theory and Practice 1st Edition

Advanced Genetic Counseling: Theory and Practice 1st Edition

Advanced Genetic Counseling: Theory and Practice

The scope and responsibilities of today’s genetic counselors exceed the reasonable capacity of any one educational resource. While the field’s first-year curriculum may be relatively fixed, the landscape of what comes after that — a dizzying mix of practice, ethics, research design, and professional competencies — is increasingly broad.

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Advanced Genetic Counseling offers an overdue extension of the field’s core curriculum. From navigating ethical dilemmas and potential conflicts of interest to confronting the biases and patterns of thought that can limit counselors’ interactions with clients, it prepares readers to face the profession’s most challenging aspects with confidence.

Drawing on techniques from psychotherapy, social psychology, and health behavior, Advanced Genetic Counseling is an essential resource for trainees and mid-career professionals. It offers a roadmap not just for addressing client needs, but for the future of genetic counseling education.

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Molecular Cloning: A Laboratory Manual,(3 volume set) 3rd Edition

Molecular Cloning: A Laboratory Manual,(3 volume set) 3rd Edition

Molecular Cloning: A Laboratory Manual,(3 volume set) 3rd Edition

The first two editions of this manual have been mainstays of molecular biology for nearly twenty years, with an unrivalled reputation for reliability, accuracy, and clarity. In this new edition, authors Joe Sambrook and David Russell have completely updated the book, revising every protocol and adding a mass of new material, to broaden its scope and maintain its unbeatable value for studies in genetics, molecular cell biology, developmental biology, microbiology, neuroscience, and immunology. Handsomely redesigned and presented in new bindings of proven durability, this three-volume work is essential for everyone using todays biomolecular techniques.

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The opening chapters describe essential techniques, some well-established, some new, that are used every day in the best laboratories for isolating, analyzing and cloning DNA molecules, both large and small. These are followed by chapters on cDNA cloning and exon trapping, amplification of DNA, generation and use of nucleic acid probes, mutagenesis, and DNA sequencing. The concluding chapters deal with methods to screen expression libraries, express cloned genes in both prokaryotes and eukaryotic cells, analyze transcripts and proteins, and detect protein-protein interactions. The Appendix is a compendium of reagents, vectors, media, technical suppliers, kits, electronic resources and other essential information. As in earlier editions, this is the only manual that explains how to achieve success in cloning and provides a wealth of information about why techniques work, how they were first developed, and how they have evolved.

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Endometrial Gene Expression: An Emerging Paradigm for Reproductive Disorders

Endometrial Gene Expression: An Emerging Paradigm for Reproductive Disorders

Endometrial Gene Expression: An Emerging Paradigm for Reproductive Disorders

The endometrium goes through cyclical changes under the influence of hormones, and immune effectors in the endometrium change their populations cyclically as well. Dynamic changes in immune effectors determine endometrial cytokine and chemokine milieus and, consequently, the endometrial immune response. Endometrial immune responses have been shown to be important for trophoblast invasion and early pregnancy. Indeed, dysregulated endometrial inflammatory immune responses are associated with reproductive failures, such as recurrent pregnancy losses, repeated implantation failure, and gynecological diseases with oncogenic potential. Hence, the investigation of endometrial gene expression may predict infertility, gynecological and oncological conditions.
This book presents the state of the art in endometrial gene expression as well as recent developmental findings relating to reproduction and reproductive disorders. It begins with a review of the genetic regulation of urogenital tract formation and molecular mechanism underlying the physiology of menstrual cycle before moving on to the current and emerging technological advances in molecular biology. Endometrial gene expressions of immune inflammatory conditions, viral infection, metabolic and nutritional conditions, and reproductive disorders are then presented in following chapters. Examples of the use and interpretation of gene expression in clinical scenarios including recurrent pregnancy losses,  infertility and multiple implantation failures are presented with currently available endometrial gene analysis.

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Genetics of Rare Autoimmune Diseases

Genetics of Rare Autoimmune Diseases

Genetics of Rare Autoimmune Diseases

The main aim of this volume is to provide an updated overview of the genetic basis of a group of complex disorders that are considered rare individually, but show a relatively high prevalence on the whole in developed countries: the rare autoimmune diseases. These are chronic disorders that involve long and expensive treatments with considerable side effects that may dramatically reduce the quality of life of affected people. Therefore, shedding light into their pathologic mechanisms is a major concern given their growing social and economic awareness and impact.

General sections include different chapters on single entities as systemic lupus and sclerosis, Behçet’s disease, Sjogren’s syndrome and polymiositis, and sections devoted to autoimmune vasculitis, hepatic autoimmune conditions, as well as those affecting the nervous system, and a concluding chapter in which the shared predisposition amongst all diseases is discussed. All the chapters are given a homogeneous scheme in which the authors explain the clinical singularities of every disease and report the recent breakthrough discoveries related to them, giving a critical interpretation and suggesting future perspectives. All contributors are renowned researchers with high expertise in each disease. Due to the exponential increase in our understanding of the genetic causes of these complex diseases, a major advance in biomedical discovery is taking place. However, most of the achievements in this field are very recent and there is a lack of bibliography gathering them together. This book is thus filling a gap and will prove a useful companion to clinicians in the first place (internists, rheumatologists, clinical immunologists, and hematologists) but also to basic and applied researchers.

 

 

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Genetics: Analysis and Principles 6th Edition

Genetics: Analysis and Principles 6th Edition

Genetics: Analysis and Principles is a one-semester, introductory genetics textbook that takes an experimental approach to understanding genetics. By weaving one or two experiments into the narrative of each chapter, students can simultaneously explore the scientific method and understand the genetic principles that have been learned from these experiments.

Rob Brooker, author of market leading texts in Genetics and Intro Biology for majors, brings his clear and accessible writing style to this latest edition.

 

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Unzip Your Genes: 5 Choices to Reveal a Radically Radiant You

This guide will show you how to take your health into your own hands. You will no longer sit on the sidelines – instead you can play an active and empowered role in the state of your own health. This book will help you:

  • Understand how the environment and your genes interact.
  • Learn how to use your own genetic information to your advantage.
  • Create an actionable plan based on your genomics to radically transform your health and improve your vitality.
  • Discover how to improve your health span and lead a productive, happy, and healthy life.

Dr. Jennifer Stagg is an experienced physician and expert in precision medicine – an emerging approach for disease prevention that takes into account an individual’s genes, environment, and lifestyle. In Unzip Your Genes, Dr. Stagg provides insight on how you can take practical steps that can radically transform the state of your health and well-being.

 

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Genetics: A Conceptual Approach Sixth Edition

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Genetics: A Conceptual Approach Sixth Edition

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With Genetics: A Conceptual Approach, Ben Pierce brings a master teacher’s experiences to the introductory genetics textbook, clarifying this complex subject by focusing on the big picture of genetics concepts and how those concepts connect to one another. The new edition continues the Pierce tradition of pedagogical excellence and scientific currency.

Genetic Neuromuscular Disorders: A Case-Based Approach

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Genetic Neuromuscular Disorders: A Case-Based Approach

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This book describes the genetic diagnostic entities of neuromuscular disorders. Each neuromuscular syndrome is presented clinically as a case study, accompanied by text reviewing different molecular defects, DNA research and differential diagnosis.

 

This collection of neuromuscular disorders features the different clinical phenotypes related to each genotype and are representative of the whole spectrum of a genetic muscle disorder, helping the clinician and neuromuscular physician to make a diagnosis. Key points for each genetic disease are identified to suggest treatment, when available, or the main clinical exams useful in follow-up of patients.

 

Genetic Neuromuscular Disorders: A Case-Based Approach is aimed at neuromuscular physicians and neurology residents.

Essential Genetics and Genomics 7th Edition

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Essential Genetics and Genomics 7th Edition

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Dan Hartl once again takes students on the exciting journey of learning about modern genetics in an updated seventh edition of Essential Genetics and Genomics. With carefully chosen topics to help students attain scientific competency, Dr. Hartl expertly covers the fundamentals of genetics from the perspective of genomics, including gene transmission, mutation, expression, and regulation. New and updated Stop & Think problems, Key Concept checks, and Human Connection feature boxes throughout chapters, along with extensive end-of-chapter review and study material that encourages students to analyze and apply new skills, further emphasize the text’s focus on student success. The seamless integration of “molecular genetics” and “classical genetics” coupled with the copious practice and problem-solving opportunities make Essential Genetics and Genomics, Seventh Edition a unique resource for learning and applying genetics to our world.

To ensure students are prepared for introductory genetics, a new online Readiness Assessment is available to complete prior to diving into the material. Students simply answer the online questions to obtain a personalized score with tailored areas to focus their review. Students are then directed to the color-coded Readiness Review section in the back of the text to practice the areas where study is needed. Sections include Math in Genetics, Science Prerequisites, and Thinking Like a Scientist. Never has learning genetics been so straightforward!

Molecular Genetic Pathology 2nd ed

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Molecular Genetic Pathology 2nd ed

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From the Back Cover

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