Melanocytic Lesions: A Case Based Approach
Melanocytic Lesions: A Case Based Approach provides a concise yet comprehensive guideline on how to diagnose common as well as problematic and challenging melanocytic lesions. In the first 11 chapters, each entity is illustrated by an actual case; followed by discussion of how the diagnosis is reached, of the histologic differential diagnoses and of diagnostic pitfalls and ends with bulleted teaching points. Pertinent and up to date references are included at the end of each chapter. The latter chapters cover current microstaging and classification of melanoma, ancillary techniques including immunohistochemistry as well as available molecular assays and molecular targeted therapy. All figures and glass slides of the discussed cases are hosted online for easy viewing and access. Melanocytic Lesions: A Case Based Approach will serves as a useful resource for pathologists, dermatologists and researchers dealing with melanocytic lesions.
Turbulent Heating and Anisotropy in the Solar Wind: A Numerical Study
This book presents two important new findings. First, it demonstrates from first principles that turbulent heating
offers an explanation for the non-adiabatic decay of proton temperature in solar wind. Until now, this was only proved with reduced or phenomenological models. Second, the book demonstrates that the two types of anisotropy of turbulent fluctuations that are observed in solar wind at 1AU originate not only from two distinct classes of conditions near the Sun but also from the imbalance in Alfvén wave populations. These anisotropies do not affect the overall turbulent heating if we take into account the relation observed in solar wind between anisotropy and Alfvén wave imbalance.
In terms of the methods used to obtain these achievements, the author shows the need to find a very delicate balance between turbulent decay and expansion losses, so as to directly solve the magnetohydrodynamic equations, including the wind expansion effects.
Congenital Deformities of the Hand and Upper Limb
This book introduces readers to all clinical aspects of congenital anomalies of the hand and upper limb, and offers extensive information on their surgical management, including plastic surgery, pediatric surgery, hand surgery, orthopedic surgery, and general surgery.
Drawing on extensive research of related cases, articles and relevant books, and over a thousand pictures of hand deformities, the book addresses the morphology, structure, and defects of hand deformities, while also providing methods for hand examination and hand function assessment.
The authors are professors and experts in plastic surgery, hand surgery, and orthopedics from China and the USA, who spent over two years composing and compiling this book.
Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ layers, ethical issues, the teratoma formation of ESCs and oncogenic risk of iPSCs are major obstacles to their clinical application. More recently, perinatal stem cells have been isolated from the umbilical cord, Wharton’s Jelly, placenta, amniotic membrane and amniotic fluid, which are normally discarded as medical waste. This book, after describing perinatal stem cells in detail, introduces readers to the various types of perinatal stem cells, addressing their characterization, banking, quality control and stability. Importantly, it also reviews the clinical applications of perinatal stem cells to therapy of diseases. Accordingly, it offers a valuable resource for clinicians, researchers and graduate students alike.
This book connects experts in the field of child assessment to provide child psychiatrists with knowledge in evaluation and educational programming. The book provides a review of the latest science behind: common learning disabilities, including etiology and guidelines for assessment/diagnosis; neurodevelopmental disorders, like learning disabilities, ADHD; psychiatric disorders in childhood such as mood and anxiety disorders; and impact learning and development protocols. The Massachusetts General Hospital Guide to Learning Disabilities evaluates the interventions that are effective in addressing these learning challenges in the context of multiple factors in a way that no other current text does. Special topics such as special education law and managing the needs of transitional age youth allow psychiatrists to support their patients’ and their families as they navigate the system. By offering a better understanding the learning needs of their patients, this texts gives readers the tools to consult with families and educators regarding how to address the learning needs of their patients at school and in other settings.
This text provides a comprehensive, state-of-the-art review of the application of image analysis focusing on the techniques which can be used in every biology and medical laboratory to automate procedures of cell analysis and to create statistics very useful for a comprehension of cell growth dynamics and the effects of drugs on them. This textbook will serve as a very useful resource for physicians and researchers dealing with, and interested in, cell analysis. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information. Advanced Imaging Techniques in Clinical Pathology will be of great value to clinical pathologists, biologists, biology researchers, and those working in the clinical and biological laboratory arena.
This volume offers an overview of the latest research on perinatal adaptation among women who have faced trauma, loss and/or adversity, both in childhood and/or as an adult, and describes the varied trajectories of adaptive and maladaptive coping that follow. The range of outcomes considered span from health-limiting (e.g. mental illness, substance use, unhealthy life style behaviours) to health-promoting (e.g. resilience and posttraumatic growth). These outcomes are examined both in relation to mothers’ experience of motherhood and parenting, and with regard to their children’s lives.
Interpersonal trauma, experienced in childhood and/or or adulthood, can have a profound effect on how women experience the transition into motherhood – from pregnancy, to childbirth, and postpartum caregiving. Women across the globe are exposed to high rates of interpersonal violence, and face the physical and emotional consequences of such events. The shift into motherhood is an emotionally evocative period in a woman’s life, entailing not only challenges, but also the potential for healing and growth.
Individual chapters will present state-of-the-art research, and will also highlight the voices of women who have personally experienced trauma, illustrating the effects on their experiences as mothers. Throughout the book, the consistent emphasis is on clinical implications and on ways that providers can create a context for healing and growth with the help of current evidence-based and promising treatment methods.
This handbook identifies the various social deficiencies widely associated with children and youth diagnosed with autism spectrum disorder (ASD). It discusses possible causes as well as the lifelong effects if these deficiencies are not addressed. The handbook presents current behavioral and curriculum-based methods for assessing social deficits. Chapters examine the various interventions that have been used to improve social skills and behavior, including video modeling, peer-mediated interventions, and script fading. Chapters also assess various interventions using empirically based procedures, evaluate the research of each of these procedures, provide guidelines for treatment planning, and offer clinical recommendations. The handbook concludes with future directions for the development of both social behavior and clinical social skills interventions.
Topics featured in the Handbook include:
- Impairments in social behavior that may result in negative outcomes such as depression, loneliness, and suicide in individuals with ASD.
- Bullying among youth with ASD.
- Behavioral skills training to promote social behavior of individuals with ASD.
- The Early Start Denver Model approach to helping young children with ASD.
- The implementation of social skills groups for individuals diagnosed with ASD.
The Handbook of Social Skills and Autism Spectrum Disorder is a must-have resource for researchers, clinicians/professionals, and graduate students in clinical child, school, and developmental psychology, behavioral therapy, and social work, as well as such interrelated disciplines as child and adolescent psychiatry, rehabilitation medicine/therapy, pediatrics, and special education/educational psychology.
Post-Intensive Care Syndrome (Lessons from the ICU)
This book, part of the European Society of Intensive Care Medicine textbook series, provides detailed up-to-date information on the physical, cognitive, and psychological impairments that are frequently present following a stay in an intensive care unit and examines in depth the available preventive and therapeutic strategies, including adapted rehabilitation programs. Beyond acquainting readers with the multiple facets of post-intensive care syndrome (PICS), the book aims to promote the effective follow-up of patients, thereby enhancing their ability to work and their functional autonomy, and to identify risk factors for the development of PICS as a stimulus to beneficial organizational changes in intensive care departments.
The background to the book is the realization by healthcare providers that the quality of life of patients who have required a stay in an intensive care unit can be severely impaired or even become unacceptable. All too often, the diverse sequelae are overlooked by specialists of other disciplines. Moreover, families and caregivers are also at high risk of post-traumatic stress disorder and depression.
The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care. This book, written by renowned experts in the field, will facilitate the transmission of key knowledge with significant clinical and financial benefits.