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Mouse Models of Cancer: Methods and Protocols (Methods in Molecular Biology Book 2773)

Mouse Models of Cancer: Methods and Protocols (Methods in Molecular Biology Book 2773) 

This detailed volume presents a variety of mouse models for cancer studies, from leukemia and lymphoma models to different types of subcutaneous and orthotopic models. Models for the healing process and the assessment of the immune response after local ablative therapies are also included, as well as imaging techniques that allow for the visualization of cancer at the cellular and tissue level. The book closes with a detailed description of necropsy, which is essential for obtaining good biomaterial for translational research. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and practical, 
Mouse Models of Cancer: Methods and Protocols serves as an ideal guide to these controlled and reproducible model experimental systems to study different aspects of cancer biology, including prevention, development, progression, and treatment.

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Onco-Nephrology 1st Edition

Onco-Nephrology 1st Edition

Kidney disease and cancer are frequent comorbidities that require specialized knowledge and expertise from both the nephrologist and the oncologist. Written by three pioneers in this growing subspecialty, Onco-Nephrology provides authoritative, definitive coverage of the mechanism and management of these two life-threatening diseases. This unique, single-volume resource covers current protocols and recommends management therapies to arrest kidney failure and allow oncologic treatments to continue and succeed.

  • Addresses acute and chronic kidney diseases that develop from a variety of cancers. This includes direct kidney injury from the malignancy, paraneoplastic effects of the cancer, and various cancer agents used to treat the malignancy.
  • Discusses key issues regarding kidney disease in patients with cancer, including conventional chemotherapeutic regimens and new novel therapies (targeted agents and immunotherapies) or the malignancies themselves that may promote kidney injury; patients with chronic kidney disease who acquire cancer unrelated to renal failure; and kidney transplantation, which has been shown to carry an increased risk of cancer.
  • Contains dedicated chapters for each class of the conventional chemotherapeutic agents, targeted cancer agents, and cancer immunotherapies including the basic science, pathogenic mechanisms of injury, clinical manifestations, and treatment.
  • Includes special chapters devoted to the individual classes of chemotherapies that relate to kidney disease for quick reference. Discusses increasingly complex problems due to more numerous and specialized anti-cancer drugs, as well as increased survival rates for both cancer and renal failure requiring long-term patient care.
  • Covers anti-VEGF (antivascular endothelial growth factor) agents and cancer immunotherapies – treatments that are being recognized for adverse kidney effects.
  • Utilizes a clear, logical format based on the ASN Core Curriculum for Onco-Nephrology, making this reference an excellent tool for board review, as well as a practical resource in daily practice.
  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

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Perloff’s Clinical Recognition of Congenital Heart Disease: Expert Consult – Online and Print 6th Edition

Perloff’s Clinical Recognition of Congenital Heart Disease: Expert Consult – Online and Print 6th Edition

Dr. Joseph Perloff is joined by Dr. Ariane Marelli to bring you a new edition of Clinical Recognition of Congenital Heart Disease. This medical reference book covers the full spectrum of CHD, from infants through adults, allowing you to effectively detect these conditions as early as possible. Be at the forefront of the field with extensive coverage of the latest innovations in clinical diagnostic methods.

  • Recognize the clinical manifestations at all stages of life for malpositioned, malformed, or absent cardiovascular chambers and vessels.

  • Grasp the full scope of the pathophysiology of CHD with well-organized, expert guidance.

  • Quickly search the contents online, download images in JPG or PPT format, and view 70 echocardiogram videos at expertconsult.com.
  • Understand the appropriate diagnostic findings for each stage of life and see rich, varied examples of characteristic findings.

Obtain the most comprehensive core knowledge you need with coverage of commonly used clinically relevant diagnostic

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clinical operative dentistry with illustrated colour atlas: dental restorative procedures: clinical conservative dentistry

clinical operative dentistry with illustrated colour atlas: dental restorative procedures: clinical conservative dentistry

This book is the ideal support at all freshly-graduated dentists. It aims to detail and justify the basic clinical procedures involved in conservative dentistry with the intention of reinforcing, understanding and improving clinical skills. It is also useful for clinicians wishing to update their treatment skills and broaden their understanding operative dentistry. It explains in detail the use of both classic and new restorative materials in various clinical situations. Clearly written and fully illustrated throughout, this practical step-by-step guide will be ideal for freshly-graduated dentists. This book answers many of the questions frequently posed by practitioners, encourages a less interventive philosophy and is an easy-to-use resource for practical dental procedures. It is well-prepared to incorporate the latest scientific developments and current research findings.

It Highlights the following key-features:

  • Richly illustrated, step-by-step descriptions of procedures presented with relevant photographs.
  • Contains an abundance of full colour, clinical illustrations to show the results that can be achieved in real life.
  • Many fresh illustrative color diagrams and tables added.
  • First chapter addresses brief review on general features of dental caries and how to diagnose it in the correct manner and caries risk assessment.
  • Then, there is another chapter addresses the various reactions of dental pulp to various stimuli and describes the various methods to protect it from different insults. Also it discusses direct and indirect pulp capping in very simple manner.
  • Also . this book have important chapter which is field isolation that discusses the different methods used in isolation of oral cavity focusing on rubber dam method. Also it illustrates how to isolate in very difficult clinical situations.
  • There is important chapter on summary of anatomical features of teeth that will enable dentists to restore defected teeth to the normal shape & size.
  • It also discusses adhesive systems used in dentistry. It also discusses the technique for esthetic composite restorations on posterior and anterior teeth.
  • Also not forget dental amalgam that the book illustrates it in very good way.
  • Also there special separate chapters to focus on class V . root caries & amp; fluoride-releasing restorative materials.
  • Furthermore it addresses the diagnosis of tooth sensitivity of non-carious origin, like dentin hypersensitivity, dental erosion and cracked tooth syndrome, together with their treatment options.

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Cancer Consult: Expertise in Clinical Practice, Volume 2: Neoplastic Hematology & Cellular Therapy 2nd Edition

Cancer Consult: Expertise in Clinical Practice, Volume 2: Neoplastic Hematology & Cellular Therapy 2nd Edition

CANCER CONSULT

New edition covering the specialties of hematology, oncology and cellular therapy, now in two volumes

Cancer Consult: Expertise in Clinical Practice, Volume 2: Neoplastic Hematology & Cellular Therapy, Second Edition includes hundreds of answers to practice-based questions covering the new principles of diagnosis, classification, staging, treatment, and outcomes in the rapidly advancing field of cancer. This textbook series also provides expert guidance in the areas of cancer-related uncertainties and controversies, including experience-based discussions. The book’s smaller size allows for easy access during medical rounds. This volume also includes:

  • Up-to-date clinically relevant information on the very latest topics such as molecular techniques, targeted therapies, immunotherapy, BMT, CAR T-cell therapy and translational cancer research
  • Sections on ALL, AML, myeloid neoplasms, CLL, Hodgkin’s and Non-Hodgkin’s lymphomas, amongst other topics
  • Streamlined, engaging content to make finding information easier and less time consuming for the reader
  • Concise and practical expert perspectives that reference key studies
  • References to the latest NCCN, ESMO, ASH, ASTCT, EBMT and other national guidelines

With its powerful focus on pragmatic clinical diagnostic, therapeutic and prognostic approaches, Cancer Consult: Expertise in Clinical Practice, Volume 2: Neoplastic Hematology & Cellular Therapy, Second Edition will help keep hematology, oncology and cellular therapy practitioners up-to-date, bridging the gaps between journal and reference literature, conferences, and their existing knowledge base. It also offers clinicians, trainees, and fellows an excellent opportunity to enhance their preparation for the ABIM, hematology and oncology fellowship and recertification exams.

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Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities 1st Edition

Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities 1st Edition

Alzheimer’s disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition. Due to its multifactorial pathogenesis, current treatments are directed against symptoms and even precise diagnosis remains difficult as the majority of cases are diagnosed symptomatically and usually confirmed only by autopsy. Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities provides a comprehensive overview from aetiology and neurochemistry to diagnosis, evaluation and management of Alzheimer’s disease, and latest therapeutic approaches. Intended to provide an introduction to all aspects of the disease and latest developments, this book is ideal for students, postgraduates and researchers in neurochemistry, neurological drug discovery and Alzheimer’s disease.

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The Biology of Cancer (Third Edition) 3rd Edition

The Biology of Cancer (Third Edition) 3rd Edition

The gold standard text in cancer biology, thoroughly updated with the latest research.


Incorporating the most important advances in the rapidly-evolving field of cancer biology, this book remains the defining course text on its subject. Students, instructors, researchers, and clinicians the world over admire its authoritative content, clear explanations, extensive full-color art program, and pedagogical features that promote a deep conceptual understanding of the science through the lens of fascinating tales of scientific discovery. This purchase offers access to the digital ebook only.

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Chest Radiology: A Resident’s Manual 1st Edition

Chest Radiology: A Resident’s Manual 1st Edition

Learn the essentials of diagnostic chest radiology with this concisely written and visually stunning manual

Chest Radiology: A Resident’s Manual is a comprehensive introduction to reading and analyzing radiologic cardiopulmonary images. Readers are guided through systemic image analysis and can further enhance their learning experience with training cases found at the end of each chapter. Cases describe and discuss frequently asked questions regarding heart failure, bronchitis, pneumonia, bronchial carcinoma, fibrosis, pleural disorders, and more. This user-friendly manual will allow the reader to confidently answer the most important and commonly encountered questions related to plain chest radiographs in daily clinical practice. The easy-to-read layout pairs explanatory text on the left page with related drawings and images on the right, allowing readers to navigate their way through each section with ease.

Features

  • More than 600 high-resolution images and illustrations demonstrate a wealth of pathology
  • Concise descriptions explain how to examine conventional x-ray and CT images
  • Numerous callout boxes in each chapter highlight key takeaway points
  • A scratch-off code provides access to a searchable online database of 250 must-know thoracic imaging cases

This practice-oriented manual is an invaluable resource and reference guide for residents and radiologists-in-training.

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Churchill’s Pocketbook of Differential Diagnosis (Churchill’s Pocketbooks) 4th Edition

Churchill’s Pocketbook of Differential Diagnosis (Churchill’s Pocketbooks) 4th Edition

Making a correct diagnosis is one of the key aspects of every medical student’s and junior doctor’s clinical training, and problem-based learning is now widely used to focus on the causes behind the presentation of a clinical feature. The Fourth Edition of this best-selling book is packed full of information to help the reader move from a presenting problem to an accurate diagnosis.

  • This Fourth Edition covers 127 common presenting problems in both medicine and surgery in a consistent format.

  • Each topic includes a list of all potential causes of the condition, colour coded to indicate common, occasional or rare causes. Important geographical variations are also highlighted.

  • Two sections cover the differential diagnosis of biochemical and haematological disorders which provide a ready check when reviewing abnormal results

  • The text includes a targeted guide to the relevant general and specific follow-up investigations which should be carried out as appropriate.

  • At the end of each topic a box highlights important learning points, or indicates symptom and signs suggestive of significant pathology which require urgent action.
  • Eighty colour photographs of key clinical presentations have been added to assist symptom recognition.

  • Two new chapters on Hypotension and Photophobia.

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Encyclopedia of Infection and Immunity (4 Volume set) 1st Edition

Encyclopedia of Infection and Immunity (4 Volume set) 1st Edition

Encyclopedia of Infection and Immunity, Four Volume Set provides new insights into the interactions between bacteria, fungi, parasites and their hosts. Specific areas of interest include host cellular and immune response to microbes, molecular mechanisms of action of beneficial microbes or host-associated microbial communities, microbial pathogenesis, virulence factors, experimental models of infection, host resistance or susceptibility, and the generation of innate and adaptive immune responses. Comprised of over 200 chapters written and edited by leading experts in the field, this book will serve as a key resource for students, researchers, academics and industry practitioners in the fields of microbiology, immunology, and infectious diseases.

More than 100 years after Robert Koch and Louis Pasteur established the microbial etiology of communicable diseases, the field of microbiology is experiencing a second period of rapid growth and expansion, driven by the realization that changes in host-associated microbial communities might be at the root of a broad spectrum of noncommunicable human diseases. These advances follow on the heels of recent progress in high-throughput sequencing technology, which has provided a wealth of information on the human microbiome and its physiological potential.

  • 2023 PROSE Awards – Winner: Finalist: Reference Works – Biological and Life Sciences: Association of American Publishers
  • Offers a contemporary review of current infection and immunity research, and insights into the future direction of the field
  • Meticulously researched and cross-referenced to allow students, researchers and professionals to find relevant information quickly and easily
  • Includes chapters written by academics and practitioners from various fields and regions, ensuring that the knowledge within is easily understood by, and applicable to, a large audience

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