Contemporary Liver Transplantation: The Successful Liver Transplant Program (Organ and Tissue Transplantation) 1st ed. 2017 Edition

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Functional Mitral and Tricuspid Regurgitation: Pathophysiology, Assessment and Treatment 1st ed. 2017 Edition

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The AIDS Pandemic: Searching for a Global Response 1st ed. 2018 Edition

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This ambitious book provides a comprehensive history of the World Health Organization (WHO) Global Programme on AIDS (GPA), using it as a unique lens to trace the global response to the AIDS pandemic. The authors describe how WHO came initially to assume leadership of the global response, relate the strategies and approaches WHO employed over the years, and expound on the factors that led to the Programme’s demise and subsequent formation of the Joint United Nations Programme on HIV/AIDS (UNAIDS). The authors examine the global impact of this momentous transition, portray the current status of the global response to AIDS, and explore the precarious situation that WHO finds itself in today as a lead United Nations agency in global health.

Several aspects of the global response – the strategies adopted, the roads taken and not taken, and the lessons learned – can provide helpful guidance to the global health community as it continues tackling the AIDS pandemic and confronts future global pandemics.

Included in the coverage:

·The response before the global response

·Building and coordinating a multi-sectoral response

·Containing the global spread of HIV

·Addressing stigma, discrimination, and human rights

·Rethinking global AIDS governance

·UNAIDS: finding its place in congested waters

The AIDS Pandemic will find an engaged audience among policymakers, students, faculty, journalists, researchers, and other health professionals working and interested in global health, public health, the World Health Organization, HIV/AIDS, global pandemics, the history of medicine, and global health policy. It will also interest those involved in international relations, international development, global affairs and governance, the United Nations, and NGOs.

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Microdomains in the Cardiovascular System (Cardiac and Vascular Biology) 1st ed. 2017 Edition

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Adaptive Sports Medicine: A Clinical Guide 1st ed. 2018 Edition

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Protein Deimination in Human Health and Disease 2nd ed. 2017 Edition

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Published in 2014,  Protein Deimination in Human Health and Disease  was the first book on this novel post-translational modification, in which selected positively-charged arginine amino acids are converted to neutral citrulline amino acids by the peptidyl-arginine deiminase (PAD) family of enzymes. This area of research continues to expand rapidly, necessitating the need for this second edition. Chronicling the latest inflammatory, epigenetic, neurodegenerative, and carcinogenic processes,  Protein Deimination in Human Health and Disease, Second Edition, updates the latest advances in deimination research, including new information on PAD enzyme structure and activity, and how PAD knock-out animals are being used to study known and newly-discovered links to various human diseases.

The first edition outlined what was known about citrullinated proteins in normal tissues such as skin and hair, as well as in maladies such as rheumatoid arthritis (RA), multiple sclerosis (MS), Alzheimer’s disease (AD), glaucoma, peripheral nerve injury, neonatal hypoxic brain damage, and breast cancer. This second edition addresses numerous additional disorders such as diabetes, asthma, traumatic brain injury, inflammatory bowel disease, lupus, bone disease, heart failure, fronto-temporal dementia, and prostate and colon cancer. It also provides updates on the deimination research covering the three seminal diseases first linked to this process (RA, MS and AD), and details how auto-antibodies against citrullinated proteins contribute to disease. In addition, new hypotheses on the possible pathologic mechanisms of citrullinated myelin basic protein and glial fibrillary acidic protein are also proposed. This second edition also outlines the latest developments in therapeutic strategies, including the use of new PAD antagonists and innovative techniques such as micro-vescicles and stem cells as possible mechanisms to treat these conditions.

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Global Perspectives on Women’s Sexual and Reproductive Health Across the Lifecourse 1st ed. 2018 Edition

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This expansive survey spotlights pervasive issues affecting girls’ and women’s sexual and reproductive health across the lifecourse. Research from diverse countries around the world analyzes the complex relationships among biological, psychological, sociocultural, and economic issues―particularly in terms of inequities―as they shape women’s lives. Major challenges and possibilities for intervention are examined in their national context and with their global implications, including child marriage/motherhood, reproductive care and access, fertility, childbearing, contraception, abortion, HIV/STIs, gender-based violence, sexual pleasure, and menopause. In these forceful dispatches, a consistent human rights perspective emphasizes women’s control, autonomy, and agency in all stages of their lives.

A sampling of topics covered:

  • Girl child marriage: a persistent global women’s health and human rights violation
  • Investigating challenges and resilience among women living with obstetric fistula in Kenya
  • A qualitative exploration of mainstream and social media reflections on abortion
  • A continuum of severity of sexual intimate partner violence among black women in the United States
  • Economic empowerment to improve sexual and reproductive health among women and girls

Summarizing an interdisciplinary field on research and practical levels, Global Perspectives on Women’s Sexual and Reproductive Health Across the Lifecourse will be an invaluable text for undergraduate and graduate courses in a wide range of fields, including public health, global health, women’s studies, sociology, anthropology, gender studies, and human rights.

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The History of Technologic Advancements in Urology 1st ed. 2018 Edition

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Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities 2nd ed. 2018 Edition

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Stakeholder Engagement: Clinical Research Cases (Issues in Business Ethics) 1st ed. 2017 Edition

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