Lung Innate Immunity and Inflammation: Methods and Protocols (Methods in Molecular Biology, 1809) 1st ed. 2018 Edition

Lung Innate Immunity and Inflammation: Methods and Protocols (Methods in Molecular Biology, 1809) 1st ed. 2018 Edition

This detailed book explores methods to isolate, characterize, and investigate key lung innate immune cells. Beginning with an overview, the volume then continues with methods for creating in vitro and in vivo model systems to study inflammatory lung diseases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Lung Innate Immunity and Inflammation: Methods and Protocols aims to be a guidebook and will be of value and interest to researchers investigating innate immunity and inflammation in the lung as well as other organs and tissues.

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Innate Antiviral Immunity: Methods and Protocols (Methods in Molecular Biology, 1656) 1st ed. 2017 Edition

Innate Antiviral Immunity: Methods and Protocols (Methods in Molecular Biology, 1656) 1st ed. 2017 Edition

This book explores methods to study the complex and evolving interplay between a virus and its host that range from model systems to the detection of chemical molecules. The collection starts with the application of humanized mice and zebrafish as model organisms to study virus-host interactions and induction of innate immune responses. Subsequent chapters outline diverse methods to detect small interfering RNAs, microRNAs, and virus-derived dsRNA from a variety of cells, tissues, and organisms, as well as to interrogating the cytosolic RNA and DNA sensing pathways, including using RNA PAMPs as molecular tools, purification of cGAMP from virus particles and infected cells, and mechanisms to visualize the subcellular localization and activation of the adaptor proteins MAVS and STING. Cutting-edge methods, including high-throughput and genome-wide CRISPR/Cas9 screens, chromosome conformation capture, and whole-exome sequencing, are described to identify novel mediators, pathways, and variants underlying host susceptibility. Given the importance of studying these pathways and players under physiologic conditions, methods describing the isolation of primary mouse sensory neurons and group 2 innate lymphoid cells are also provided. Finally, this collection comes full circle back to the whole organism level and concludes with epidemiological methods to investigate virus-host interactions and the induction of innate immunity. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and practical, 
Innate Antiviral Immunity: Methods and Protocols spans a diverse array of approaches to study and elucidate the intricacies of this vital area of study.
The chapter ‘Morphological Separation ofClustered Nuclei in Histological Images’ is published open access under a CC BY 4.0 license at link.springer.com. 

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Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support 1st Edition

Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support 1st Edition

Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health.

Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions.

This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here.

  • Conceptualizes the key features in natural products which can boost immune function and immune health
  • Explains the intricate mechanistic aspects and balance behind immune health
  • Presents the pathophysiology of several diseases associated with immune system disruption

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Boosting Your Immunity For Dummies

Boosting Your Immunity For Dummies

Boost your body’s defenses to fight-off disease and live stronger and longer

Every single day our bodies are under attack from nasty little organisms which range from the pesky to the frighteningly serious. So, what’s the best way to fight back? Thankfully nature has provided us with a powerful interior armor-plating―and Boosting Your Immunity For Dummies shows you how to keep that crucial biological gift in tip-top condition.

Brought to you by bestselling author Kellyann Petrucci, MS, ND, a board-certified naturopathic physician, and Wendy Warner, a board certified holistic physician,―Boosting Your Immunity For Dummies sets out the sound ways we can supercharge our immune systems to prevent illnesses and diseases such as arthritis, autoimmune conditions, pneumonia, cancer, and the flu. Using a simple program of diet, exercise, stress-reduction, and nutritional supplements, we can keep our internal defenses humming happily along―and get generally healthier in the process!

  • The best nutritional strategies to avoid cold and flu
  • 40+ recipes that show healthy eating can also be delish
  • Cutting-edge research on immune-boosting health and diet
  • Lists and tips for keeping a low-cost, healthy pantry

Through diet, exercise, stress reduction, nutritional supplements, and the role of water, sunlight, and oxygen, you can harness the power of your immune system and drastically improve your immunity to disease.

P.S. If you think this book seems familiar, you’re probably right. The Dummies team updated the cover and design to give the book a fresh feel, but the content is the same as the previous release of Boosting Your Immunity For Dummies (9781118402009 find this on the copyright page). The book you see here shouldn’t be considered a new or updated product. But if you’re in the mood to learn something new, check out some of our other books. We’re always writing about new topics!

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Mayo Clinic Internal Medicine Board Review (Mayo Clinic Scientific Press) 12th Edition

Mayo Clinic Internal Medicine Board Review (Mayo Clinic Scientific Press) 12th Edition

The key resource you need to prepare for the American Board of Internal Medicine (ABIM) Certification and Maintenance of Certification examinations.
Now in its twelfth edition, Mayo Clinic Internal Medicine Board Review builds on years of knowledge, refinement, and expertise from Mayo Clinic’s Department of Medicine and the successful certification process, providing the latest information you need. Now including Physician Well-Being and Hospital Internal Medicine, over 80 chapters help you confidently sit for the boards.
Not preparing to certify or recertify? This all-inclusive reader-friendly volume is the perfect companion for anyone seeking to provide state-of-the-art care to patients, to serve as a core textbook for internal medicine residency training, or for students preparing for USMLE Step 3 examinations.

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Immunology: An Illustrated Outline 6th Edition

Immunology: An Illustrated Outline 6th Edition

Immunology: An Illustrated Outline is both a guide to the essential principles of immunology and a concise dictionary of immunological terms. The book can be used to consolidate understanding in preparation for course exams and medical licensing exams, or as a refresher when immunology is encountered in related life sciences, such as microbiology, virology, and zoology.

The book is organized into five sections that represent the major topics in basic and clinical immunology. The Sixth Edition has been comprehensively revised to highlight the latest understanding of the field, particularly in the areas of innate immune defenses and antibody-based therapeutics.

  • Concise explanations of immunological terms
  • Full-color illustrations and micrographs to reinforce the text
  • Each topic is set out in single- or double-page spreads
  • Tables collate and summarize detailed information

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Essential Endocrinology and Diabetes (Essentials) 7th Edition,

Essential Endocrinology and Diabetes (Essentials) 7th Edition

ESSENTIAL ENDOCRINOLOGY AND DIABETES

The Essentials are an international, best-selling series of textbooks, all of which are designed to support lecture series or themes on core topics within the health sciences. See www.wiley.com for further details.

Essential Endocrinology and Diabetes provides the accurate and up-to-date knowledge required for treating all areas of endocrinology and diabetes, covering the latest research, clinical guidelines, investigational methods, and therapies. This classic text explains the vital aspects of endocrine physiology in a succinct and easy-to-use format, with full-colour illustrations, clinical images, and case studies to assist readers in applying theory to practice.

The text covers the principles of endocrinology, clinical endocrinology, and clinical diabetes and obesity, and has been revised throughout to present the most recent developments in the field. The seventh edition includes new and updated material on the latest molecular techniques, approaches to clinical investigation and diagnostics, next generation sequencing technology, and positron emission tomography (PET). The treatment of type 1 diabetes and type 2 diabetes has been updated with clinical algorithms and reflects significant advances such as incretin-based therapies, SGLT2 inhibitors, the development of better insulins, and technologies that support self-management.

  • Provides students and practitioners with comprehensive and authoritative information on all major aspects of endocrine physiology
  • Covers diagnosis, management, and complications of clinical disorders such as endocrine neoplasia, and type 1 diabetes and type 2 diabetes

Explains the core principle of feedback regulation, which is vital for the correct interpretation of many clinical tests

  • Features case histories, learning objectives, ‘recap’ links to chapter content, cross-referencing guides, key information boxes, and chapter summaries

Essential Endocrinology and Diabetes, Seventh Edition is the ideal textbook for medical and biomedical students, junior doctors, and clinicians looking to refresh their knowledge of endocrine science.

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Thoracic Imaging: A Core Review 2nd Edition

Thoracic Imaging: A Core Review 2nd Edition

Prepare for success on the thoracic imaging component of the radiology Core Exam! Thoracic Imaging: A Core Review, 2nd Edition, is an up-to-date, practical review tool written specifically for the Core Exam. This helpful resource contains 300 image-rich, multiple-choice questions with detailed explanations of right and wrong answers, fully revised content, and additional eBook questions to ensure you’re ready for the Core Exam or recertification exam.

  • Features questions in all exam areas, including imaging basics, normal anatomy, ICU radiographs, pulmonary pathology, pleural disease, vascular diseases relevant to thoracic imaging, and trauma.
  • Questions accompanied with 1 or 2 high-quality radiographs, CT, MR, or ultrasound images.
  • Provides concise answers with explanations of each choice followed by relevant, up-to-date references.
  • Follows the structure and content of what you’ll encounter on the test, conveniently organized by topic. 

Enrich Your eBook Reading Experience

  • Read directly on your preferred device(s), such as computer, tablet, or smartphone.
  • Easily convert to audiobook, powering your content with natural language text-to-speech.

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Pathophysiology: The Biologic Basis for Disease in Adults and Children 8th Edition

Pathophysiology: The Biologic Basis for Disease in Adults and Children 8th Edition

Learn the what, how, and why of pathophysiology! With easy-to-readin-depthdescriptions of disease, disease etiology, and disease processes, Pathophysiology: The Biologic Basis for Disease in Adults and Children, 8th Edition helps you understand the most important and most complex pathophysiology concepts. This updated text includes more than 1,300 full-color illustrations and photographs to make it easier to identify normal anatomy and physiology, as well as alterations of function. This edition includes a NEW chapter on obesity and nutritional disorders, along withexpanded coverage of rare diseases and epigenetics. It’s the most comprehensive and authoritative pathophysiology text available!

  • The most comprehensive and authoritative pathophysiology text on the market provides unparalleled coverage of Pathophysiology content.
  • Over 1,300 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes ― more than in any other pathophysiology text.
  • Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment.
  • Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content.
  • Outstanding authors Kathryn McCance and Sue Huether have extensive backgrounds as researchers and instructors, and utilize expert contributors, consultants, and reviewers in developing this edition.
  • Algorithms and flowcharts of diseases and disorders make it easy for you to follow the sequential progression of disease processes.
  • Additional What’s New boxes highlight the most current research and clinical development.
  • Nutrition and Disease boxes explain the link between concepts of health promotion and disease.
  • Chapter summary reviews provide concise synopses of the main points of each chapter.
  • NEW! Chapter on obesity and nutritional disorders thoroughly covers these growing global concerns.
  • NEW! Added coverage of rare diseases and epigenetics further explore genetic disease traits.
  • NEW! Over 50 new or heavily revised illustrations visually highlight pathophysiology concepts.
  • NEW! More than 30 new 3D animations on Evolve bring difficult concepts to life for a new perspective on disease processes.

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Comprehensive Pharmacology 1st Edition

Comprehensive Pharmacology 1st Edition

Comprehensive Pharmacology, Seven Volume Set is organized into twelve sections that explore therapeutic areas, with a total of 320 comprehensive articles and 6,800 pages of important findings. Sections contain highly detailed coverage of information that has been overseen by an editorial board made up of well-respected, field leading experts. The content in this book offers readers an in-depth and easily accessible reference work on every aspect of pharmacological research surrounding the pharmacology of all therapeutic applications of drugs, their mechanism of action and their therapeutic values.

These elements are essential as drugs are almost never tested and developed in the actual therapeutic system, but rather in test systems from which parameters must be determined to predict activity in systems of varying ambient physiology. As different technologies rapidly evolve, there is an ever-increasing level of knowledge about the pharmacology of known drugs, along with increasing capability to utilize pharmacological systems to predict new drug activity, all of which must be communicated to professionals in varying fields.

  • Contains chapters that follow a consistent and templated approach, resulting in well-structured content that enhances user experience and appeal
  • Offers a comprehensive review on a wealth of information on pharmacology and how it utilizes concepts and techniques from a broad array of sciences, ranging from chemistry to physiology to medicine
  • Includes a wider use of color and multimedia content, with interactive features, links, computational modeling and animations to illustrate the effects of toxic substances in various contexts

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