Behavior and Immunity (Routledge Revivals) 1st Edition

First publishe din 1992: Find out by reading Behavior and Immunity, a new volume that consists of papers presented at the Scientific Meeting of the Australian Behavioral Immunology Group (ABIG) held in November, 1990, at the University of Newcastle, Australia. The ABIG was established in response to the need to provide a forum for the presentation of data and exchange of ideas regarding the concept of brain, behavior, and immunity. The papers presented in this volume represent the state of the art in a number of areas where these interactions have been studied. Information is presented regarding the biochemistry, neurophysiology, and endocrinology of nervous system/immune system interactions; the role of behavioral conditioning in immunity; the effects of sleep and biological rhythms on immune function; the role of lifestyle, life events, and exercise in immunity; and the impact of psychoimmunology in clinical medicine. Researchers in immunology, psychology, neurology; physicians; and lay people with an interest in the interaction between lifestyle and health will find a wealth of information in this stimulating volume.

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Transplantation Immunology: Methods and Protocols (Methods in Molecular Biology, 333) 2006th Edition

Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today’s optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.

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The Immune System: A Very Short Introduction (Very Short Introductions) Illustrated Edition

The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.

In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. The immune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called “innate” immune responses, which react very fast to infection, and “adaptive” immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading to serious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the “Immune system v2.o” – how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.

ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

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Type 2 Immunity: Methods and Protocols (Methods in Molecular Biology, 1799) 1st ed. 2018 Edition

This book provides researchers the opportunity to investigate type-2-associated diseases in their laboratories. Beginning with chapters describing various models of type-2 immunity, the volume then continues by detailing cellular protocols designed to identify, characterize, and assess the function of key adaptive and innate immune cells involved in type-2 inflammation; approaches to isolate and evaluate specific cellular subsets at the genetic, epigenetic, and molecular level; protocols to assess type-2 immunity and its relationship to organismal and metabolic systems (ex. Microbiome). This book concludes with a section that explores the use of primary human cells in evaluating relevance to the clinic. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshootingand avoiding known pitfalls.

Vital and authoritative, Type 2 Immunity: Methods and Protocols aims to provide a broad network of methods that can be used to develop a hypothesis and investigate its potential from bench to beside.

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The 21-Day Immunity Plan

**THE SUNDAY TIMES BESTSELLER**

‘Brilliant! It’s hard to change your life – but this book gives you all the reasons it’s possible. From the first page to the last, one revelation after another.’
JEREMY VINE

‘Brilliant . . . especially required reading in these COVID-19 days’
LIZ EARLE

‘Metabolism, inflammation, and immunity are three sides of the same coin. Fix one and you fix them all. Dr Aseem Malhotra offers you a way to fix all three at once, and the solution is as easy as your fork.’
PROFESSOR ROBERT LUSTIG, bestselling author of Fat Chance

‘This remarkable book will change your life. Beautifully written, it compiles in one place the health messages we all know make sense.
PROFESSOR KAROL SIKORA, leading cancer specialist and Founding Dean, University of Buckingham Medical School

‘Read this book and follow the plan, it may save your life.’
GURINDER CHADHA, OBE, director of Bend It Like Beckham

‘A crystal-clear roadmap to reverse the roots causes of our poor metabolic and immune health. It is the handbook of health for our time.’
MARK HYMAN, New York Times bestselling author of Food Fix

*******

The simple, evidence-based diet plan to rapidly improve your metabolic health, help with normal immune function and likely reduce the risk of severe effects from Covid-19.

Dr Aseem Malhotra is a leading NHS-trained cardiologist and a pioneer of lifestyle medicine. He has been at the forefront of citing the health conditions which make us vulnerable to the worst effects of Covid-19. Obesity, Type 2 diabetes and heart disease are high among them – and all indicators of poor metabolic health.

The good news is that in just 21 days we can prevent, improve and even potentially reverse many of the underlying risk factors that exacerbate how infections, including Covid-19, affect us and improve our ability to recover from them.

Giving us the evidence-based science behind the plan, Dr Malhotra shares how simple changes to our diet as well as daily exercise and stress relief can have remarkable results in improving our markers for metabolic health, even helping to put Type 2 diabetes into remission, reduce risk factors for heart disease, decrease weight and enhance vitality.

Arguing for the huge benefits to global health of these highly effective lifestyle changes, he shows how just 21 days can help us to start the journey to lead a healthier and longer life.

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AI for Immunology (AI for Everything) 1st Edition

The bioscience of immunology has given us a better understanding of human health and disease. Artificial intelligence (AI) has elevated that understanding and its applications in immunology to new levels. Together, AI for immunology is an advancing horizon in health care, disease diagnosis, and prevention. From the simple cold to the most advanced autoimmune disorders and now pandemics, AI for immunology is unlocking the causes and cures.

 

Key features:

 

 

 

• A highly accessible and wide-ranging short introduction to AI for immunology

 

 

 

• Includes a chapter on COVID-19 and pandemics

 

 

 

• Includes scientific and clinical considerations, as well as immune and autoimmune diseases

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Systems Immunology: An Introduction to Modeling Methods for Scientists (Foundations of Biochemistry and Biophysics) 1st Edition

“Taken together, the body of information contained in this book provides readers with a bird’s-eye view of different aspects of exciting work at the convergence of disciplines that will ultimately lead to a future where we understand how immunity is regulated, and how we can harness this knowledge toward practical ends that reduce human suffering. I commend the editors for putting this volume together.”

–Arup K. Chakraborty, Robert T. Haslam Professor of Chemical Engineering, and Professor of Physics, Chemistry, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, USA

New experimental techniques in immunology have produced large and complex data sets that require quantitative modeling for analysis. This book provides a complete overview of computational immunology, from basic concepts to mathematical modeling at the single molecule, cellular, organism, and population levels. It showcases modern mechanistic models and their use in making predictions, designing experiments, and elucidating underlying biochemical processes. It begins with an introduction to data analysis, approximations, and assumptions used in model building. Core chapters address models and methods for studying immune responses, with fundamental concepts clearly defined.

Readers from immunology, quantitative biology, and applied physics will benefit from the following:

• Fundamental principles of computational immunology and modern quantitative methods for studying immune response at the single molecule, cellular, organism, and population levels.

• An overview of basic concepts in modeling and data analysis.

• Coverage of topics where mechanistic modeling has contributed substantially to current understanding.

• Discussion of genetic diversity of the immune system, cell signaling in the immune system, immune response at the cell population scale, and ecology of host-pathogen interactions.

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Principles of Mucosal Immunology 2nd Edition

This respected graduate-level textbook provides comprehensive and accessible coverage of the basic and clinical aspects of the mucosal immune system, addressing the major components of the mucosal barrier ̶ gastrointestinal, upper and lower respiratory, ocular, and genitourinary mucosal immune systems ̶ in a highly user-friendly style. The editors of and contributors to the book, all internationally-recognized leaders, present the current principles, concepts, and basic processes involved in mucosal immunology, mucosal diseases, and host defense at mucosal surfaces. Topics discussed include the development and structure of the mucosal immune system and its cellular constituents, host-microbe relationships, infection, mucosal diseases, and vaccines. The second edition has been carefully updated throughout to reflect the latest developments from clinical research and key literature has been fully updated.

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