Pediatric and Adolescent Oncofertility: Best Practices and Emerging Technologies 1st ed

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Reflecting the increasing interest in fertility management for pediatric and adolescent patients and fulfilling an urgent need to have a comprehensive guide to the management of these individuals, this is the first book of its kind to present a comprehensive discussion of pediatric and adolescent oncofertility. It carefully examines the impact of pediatric cancer and cancer therapy on fertility and presents both current and emerging fertility preservation techniques for both males and females, such as cryopreservation. Fertility concerns beyond cancer are also discussed, including disorders of sexual differentiation, gender dysphoria and thalassemia. Practical chapters on pediatric oncofertility in the clinic round out the book, covering setting up a practice, counseling and consent, disclosure and insurance considerations. Concluding chapters document fertility preservation techniques and outcomes internationally, with contributions from Portuguese, Brazilian and Japanese authors. Timely and wide-ranging, Pediatric and Adolescent Oncofertility is an ideal resource for reproductive medicine specialists, pediatric oncologists, and primary care physicians treating pediatric and adolescent cancer patients looking to protect fertility options.

Pediatric Digestive Surgery 1st ed

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This book presents and explains the latest developments in surgery for congenital digestive tract malformations, tumors, abdominal trauma, and the most important acquired digestive disorders. Particular attention is paid to minimally invasive and innovative techniques. In addition to clear descriptions of the surgical procedures that highlight useful tips and tricks, for each condition the clinical presentation is well illustrated and information is provided on pathogenesis. The book also includes general chapters that address the anatomy of the abdomen in children, diagnostic issues, the problem of clinical nutrition, and other aspects of management in pediatric patients with gastrointestinal pathologies. Pediatric Digestive Surgery will serve as a comprehensive and up-to-date reference for all pediatric surgeons. It will provide the trainee with easily understood, concise guidance while offering the more experienced surgeon valuable updates on the latest thinking and practice in the field.

Imaging and Diagnosis in Pediatric Brain Tumor Studies 1st ed

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This book describes the features in structural imaging of the most important pediatric brain tumors with the aim of enabling radiologists to make the correct differential diagnosis and to provide the pediatric oncologist with all the imaging information relevant to further management. The opening chapter is devoted to the complex subject of pediatric trials at the national and international levels and the importance of staging for stratification, differential treatment, and outcome. A general imaging protocol for children with brain tumors is presented, and individual chapters then identify key points for the differential diagnosis and staging of posterior fossa tumors, low- and high-grade gliomas, germ cell tumors, and craniopharyngiomas. The relevance of aspects such as tumor site and age to diagnosis is explained, and pitfalls associated with meningeal dissemination and treatment-related complications mimicking recurrence are highlighted. The importance of ensuring comparability of follow-up by use of standard MR (or CT) imaging is emphasized. In drawing on the lessons gained both from pediatric trials and from the author’s own experience, this book will be invaluable for all radiologists.

Immunotherapy for Pediatric Malignancies 1st ed

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This book provides a comprehensive overview of current immunotherapy strategies, and how these may be applicable to childhood cancers. The first part of the book reviews how the immune system recognizes cancer, and the various escape mechanisms allowing tumour growth. The importance of the tumor microenvironment and the challenges this may present to achieving effective immunotherapy are discussed. Monoclonal antibodies, cellular, cytokine and vaccine therapies are all comprehensively reviewed, with particular focus on their potential application to pediatric cancers. Practical aspects of delivering such therapies to children, likely toxicities and potential biomarkers are considered. Finally, consideration is given to how, in the longer term, such therapies may be combined with conventional therapies such as chemotherapy and radiotherapy.

Edited by two distinguished pediatric oncologists with a collection of chapters from the most authoritative experts in cancer immunotherapy, this is an indispensable volume for pediatric oncologists and physicians working in childhood cancer care.

The Pediatric Anterior Cruciate Ligament: Evaluation and Management Strategies 1st ed

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This unique book fills the void in the existing literature related to the diagnosis and evaluation of pediatric ACL injuries and presents both current and emerging surgical techniques for pediatric ACL reconstruction. Once considered rare, these injuries are on the rise as children are increasingly active and engaged in high-impact sports. Historically, these injuries have been treated with benign neglect, but there is increasing evidence that non-operative treatment approaches can lead to recurrent instability, further injury to the meniscus or cartilage, and eventually joint degeneration.

Opening with discussion of epidemiology, developmental anatomy, and assessment and radiography, this one-stop resource then presents conservative and surgical management strategies and algorithms, including ACL reconstruction without bone tunnels, use of epiphyseal tunnels, trans-physeal tunnels, or hybrid techniques. Special attention is given to the young female athlete, complications, prevention strategies, rehabilitation and return to play considerations.

Bringing together the latest clinical evidence with the preferred techniques of experts in the field, The Pediatric Anterior Cruciate Ligament is a comprehensive and detailed analysis of the inherent problems in treating ACL injuries in the pediatric patient, useful for pediatric orthopedic surgeons, orthopedic sports medicine surgeons, primary care sports medicine physicians and other professionals working with the young athlete.

Palliative Care in Pediatric Oncology 1st ed

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This textbook is the first to focus on comprehensive interdisciplinary care approaches aimed at enhancing the wellbeing of children with cancer and their families throughout the illness experience. Among the topics addressed are the epidemiology of pediatric cancer distress, including physical, emotional, social, and spiritual dimensions; the role of the interdisciplinary team; communication and advance care planning; symptom prevention and management; care at the end of life; family bereavement care; and approaches to ease clinician distress.  The contributing authors are true experts and provide guidance based on the highest available level of evidence in the field. The book has not only an interdisciplinary but also an international perspective; it will appeal globally to all clinicians caring for children with cancer, including physicians, nurses, psychosocial clinicians, and chaplains, among others.

Imaging Non-traumatic Abdominal Emergencies in Pediatric Patients

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This book provides up-to-date, comprehensive, and accurate information on the diagnostic imaging of nontraumatic abdominal emergencies in pediatric patients. All of the most common neonatal and pediatric emergencies are covered, with separate discussion of diseases that occur more commonly in newborns and those typically encountered later in childhood. For each condition, the main signs observed using the various imaging techniques – X-ray, Ultrasonography, Computed Tomography, and Magnetic Resonance – are described and illustrated with the aid of a wealth of images. Attention is drawn to those features of particular relevance to differential diagnosis, and the prognostic value of diagnostic imaging is also explained. The final section addresses topics of special interest, including the acute onset of abdominal neoplasms, the problems associated with radiation protection in the emergency setting, and medicolegal issues and informed content. The book will be of value for all radiologists working in emergency settings in which pediatric patients (newborn and children accessing the emergency department) are regularly examined.

Pediatric Obesity: Etiology, Pathogenesis, and Treatment

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Childhood obesity and its co-morbidities — including type 2 diabetes, hypertension, dyslipidemia, sleep apnea, and fatty liver disease — have seen striking increases in recent years. Despite a wealth of investigation, there is considerable controversy regarding the etiology of childhood obesity and the optimal approaches for prevention and treatment. Pediatric Obesity: Etiology, Pathogenesis, and Treatment addresses the controversy with a range of features that make it a unique resource for those who care for obese children and their families. Written from a perspective that is international in scope, the distinguished authors re-assess the roles of genetic and environmental factors in the pathogenesis of childhood obesity and critically review new studies of the effects of lifestyle, pharmacologic, and surgical interventions. The evidence-based approach of Pediatric Obesity: Etiology, Pathogenesis, and Treatment provides a comprehensive and invaluable guide for all healthcare providers concerned with the evaluation and care of children with nutritional and metabolic disease and with the societal implications of the obesity epidemic.

Pediatric Hypertension 4th ed. 2018 Edition

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From the Back Cover

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