Breast Cancer: Recent Advances in Biology, Imaging and Therapeutics

This book considers breast cancer from many novel and exciting perspectives. New insights into the basic biology of breast cancer are discussed together with high throughput approaches to molecular profiling. Innovative strategies for diagnosis and imaging are presented as well as emerging perspectives on breast cancer treatment.

Each of the topics in this volume is addressed by respected experts in their fields and it is hoped that readers will be stimulated and challenged by the contents.

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Breast Cancer: From Biology to Medicine

This volume thoroughly examines breast cancer from basic definitions, to cellular and molecular biology, to diagnosis and treatment. This book also has some additional focus on preclinical and clinical results in diagnosis and treatment of breast cancer.

The book begins with introduction on epidemiology and pathophysiology of breast cancer in Section 1.
In Section 2, the subsequent chapters introduce molecular and cellular biology of breast cancer with some particular signaling pathways, the gene expression, as well as the gene methylation and genomic imprinting, especially the existence of breast cancer stem cells. In Section 3, some new diagnostic methods and updated therapies from surgery, chemotherapy, hormone therapy, immunotherapy, radiotherapy, and some complementary therapies are discussed.
This book provides a succinct yet comprehensive overview of breast cancer for advanced students, graduate students, and researchers as well as those working with breast cancer in a clinical setting.

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EKG’s for Nursing Demystified (Demystified Nursing) 1st Edition

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The quick and easy way to master EKG procedures and use your knowledge in real-world situations

If you’re looking for a fun, fast review that boils EKGs down to the most essential, must-know points your search ends here! EKG for Nursing Demystified is a thorough yet concise overview of this medical test, complete with time-proven techniques, facsimiles of EKG strips, and numerous clinical cases. You will learn how to interpret hypertrophy and enlargement, arrhythmias, conduction blocks, Pre-excitation syndromes, myocardial infarction and more, so you have the knowledge to help your patients as a student and as a nurse once you start your career.

This fast and easy guide offers:

  • Learning objectives at the beginning of each chapter
  • A foundation in EKG topics
  • A final exam at the end of the book
  • A time-saving approach to performing better on an exam or at work

Simple enough for a student, but comprehensive enough for a professional, EKG for Nursing Demystified is your shortcut to mastering this critical topic.

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CrossWards USMLE Step 2 Board Review 1 Csm Edition

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CrossWards USMLE Step 2 Board Review is the first in a new series of crossword-puzzle books that provides an interactive and entertaining form of board review. Covering the critical concepts and questions needed to ace USMLE Steps 1 and 2 and prepare for ward rotations, the puzzles are loaded with clever clues and quick facts. Use this fun-yet-fundamental board review for study breaks on the ward or to refresh your knowledge on the interview trail. Even when puzzles are completed, you can use this handy resource for shelf exam review and board exam preparation.   

  • Challenge yourself with 50 puzzles, averaging 30-35 clues apiece, that provide approximately 1500-1750 questions in all!
  • Review important clinical information in a fun and memorable way as you work through each puzzle.
  • Survive “pimping” by retaining the quick facts you need to answer any difficult question an attending poses.
  • Power your prep by downloading additional puzzles (and annotated solutions) online.

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Cases in Structural Cardiac Intervention 1st ed. 2017 Edition

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Multimodality cardiovascular imaging is essential for interventional cardiac procedures and both fields are evolving rapidly. Multimodality Imaging in Cardiac Interventions captures the current state of clinical utility and provides a unique visual aide for teaching, training, and education. The editors have brought together a variety of leading experts from across the United Kingdom to guide the interested viewer in the indications and practicalities of state-of-the-art techniques.  This book visually demonstrates the indications and methodology involved in several important cardiac  interventions that rely heavily on multimodality cardiovascular imaging for their success. Chapters cover topics such as transcatheter aortic valve implantation (TAVI), device closure of paravalvular leaks in the mitral and aortic positions, and the adjunctive use of computed tomographic angiography in percutaneous coronary intervention. Visual  simplicity in combination with excellent narration from experts in the field results in a unique up-to-date educational tool.  This book will appeal to a wide range of professionals from clinicians to potential patients and the medical press interested in learning about important advances in cardiovascular medicine.

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Endovascular Aortic Repair: Current Techniques with Fenestrated, Branched and Parallel Stent-Grafts 1st ed. 2017 Edition

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This text provides a comprehensive, state-of-the art review of complex endovascular aortic techniques. It will serve as a valuable resource for vascular and cardiovascular surgeons, interventionalists, cardiologists, clinicians, bioengineers and researchers with an interest in complex aortic diseases. The book reviews imaging modalities, diagnostic work up and novel endovascular approaches. Technical aspects are provided by experts in the field, with over 600 illustrations and photographs of key steps for each type of procedure. Results of epidemiologic studies and national databases are summarized, as well as large institutional experiences. An evidence-based approach is used for recommendations regarding best therapies. Other highlights of this unique text include: A new, state-of-the-art review on fenestrated, branched and parallel stent-graft techniques from procedure planning to stent design and implantation. A text dedicated to a topic that has been increasingly recognized by vascular specialists as a priority area in aortic management. An updated overview of current designs and future developments. Special attention to technical details of the procedures with use of illustrations. Technical tips on how to get out of problems during these challenging procedures.

Endovascular Aortic Repair: Current Techniques with Fenestrated, Branched and Parallel Stent-Grafts will serve as a very useful resource for physicians and researchers dealing with and interested in complex aortic diseases. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

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Handbook of Image-Guided Brachytherapy 1st ed. 2017 Edition

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This handbook provides a clinically relevant, succinct, and comprehensive overview of image-guided brachytherapy. Throughout the last decade, the utility of image guidance in brachytherapy has increased to enhance procedural development, treatment planning, and radiation delivery in an effort to optimize safety and clinical outcomes. Organized into two parts, the book discusses physics and radiobiology principles of brachytherapy as well as clinical applications of image-guided brachytherapy for various disease sites (central nervous system, eye, head and neck, breast, lung, gastrointestinal, genitourinary, gynecologic, sarcoma, and skin).  It also describes the incorporation of imaging techniques such as CT, MRI, and ultrasound into brachytherapy procedures and planning. Featuring procedural and anesthesia care, extensive images, contouring examples, treatment planning techniques, and dosimetry for the comprehensive treatment for each disease site, Handbook of Image-Guided Brachytherapy is a valuable resource for practicing radiation oncologists, physicists, dosimetrists,  residents, and medical students.

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Urogenital Pain: A Clinicians Guide to Diagnosis and Interventional Treatments 1st ed. 2017 Edition

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This book provides an up to date, comprehensive, review of the common urogenital painful conditions. It will serve as a valuable resource for clinicians, urologists, surgeons, gynecologists, palliative care physicians, and many other medical providers. The book reviews presenting signs and symptoms, diagnostic workup, differential diagnoses, interventional treatments, and alternative medical therapy for painful conditions that occur in the urogenital region. The text also provides a clear understanding of how pain is transmitted along with what patient populations are at increased risk in suffering these conditions. The risks, benefits, and indications are discussed in detail for the variety of interventional injections that are available to help manage these conditions.

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Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins (Milestones in Drug Therapy) 1st ed. 2017 Edition

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This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities.

The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.

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Platelets in Thrombotic and Non-Thrombotic Disorders: Pathophysiology, Pharmacology and Therapeutics: an Update 1st ed. 2017 Edition

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This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

Review

“The four editors have managed very well in having internationally renowned investigators reviewing their particular fields of interest related to platelet research and the result is a beautiful piece of work! I strongly recommend this book to those involved in medicine in general and vascular medicine and hemostasis and thrombosis research in particular!” H. ten Cate, Pathophysiology of Haemostasis and Thrombosis

“…provides a comprehensive, up-to-date and detailed insight into platelet biology…all the chapters are well written by leaders in their field…this book serves as an invaluable reference source and is a ‘must have’ for postgraduate students, clinicians and researchers, whether relative novices or experts in the field.” Transfusion Medicine

“[A] landmark in hematology…comprehensive coverage of platelet biology and pathology. The editors have assembled the best authors, and the authors have all provided thorough reviews with comprehensive, current citations.” The New England Journal of Medicine

“Such a comprehensive collection of platelet structure, function, and pathology has not been achieved before. This is the complete, comprehensive reference for platelets and it is invaluable to anyone who is involved in the treatment or the study of conditions related to platelets.” Doody’s Review Service

“There has been no comprehensive, timely, and authoritative reference book covering the subject in recent years. Platelets in Thrombotic and Non-thrombotic Disorders fills this gap by providing a book that is both detailed and exhaustive yet easily consulted for the latest developments.” Chest

“Obligatory reading for anyone who wishes to embark on platelet studies.” International Society on Thrombosis and Haemostasis

” Platelets in Thrombiotic and Non-thrombiotic Disorders is an highly informative and extensively referenced textbook that is highly recommended…” Immunohematology

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