Orthopedics ⋆ Page 18 of 27 ⋆ eMEDICAL BOOKS

Bone Toxicology (Molecular and Integrative Toxicology) 1st ed. 2017 Edition

October 10, 2017

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The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments. The book is divided into three parts. The first part describes our current understanding of bone biology and its primary regulatory pathways. Additional chapters address regulatory and study design considerations for incorporating bone end points in toxicology studies, with special consideration being given to juvenile toxicology studies. This is intended to address recent regulatory requirements to evaluate skeletal development for drugs in development for pediatric populations. The second part of the book describes the principal techniques and methods used in bone research; understanding how these end-points are derived is fundamental to their appropriate application. These first two parts of the book provide the background and the means to develop the concepts in part three which describes bone and its interaction with other organ systems. The unique series of chapters in part three, contributed to by key leaders in their respective fields and in bone research, provides a comprehensive collective work. Although constantly evolving, the crosstalk and interaction of the skeleton with several organ systems is now recognized and well documented, such as for the reproductive system, muscle and kidney, while our understanding of the interaction with other organ systems, such as the immune system and CNS, is in its infancy. Recent work highlights the key role of the skeleton in the regulation of energy metabolism and the impact this has on research in metabolic diseases such as obesity and diabetes. The hope is that this book will enlighten many and encourage more to explore the impact of new compounds on the skeleton in the development of effective and safe drugs.

About the Author

Susan Y. Smith is a consultant who specializes in nonclinical muscoloskeletal research. She provides guidance for the conduct of pharmacology, efficacy or safety studies, or help with data interpretation to unravel the mysteries of skeletal evaluations. She received a Master of Science in Pharmacology at McGill University and later joined Charles River Laboratories for almost 18 years and where she became Senior Scientific Director of Musculoskeletal Research. She has over 30 years of experience in preclinical safety assessments and toxicology and over 20 years of expertise in bone research.

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Diagnostic Clusters in Shoulder Conditions 1st ed. 2017 Edition

October 10, 2017

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This book serves as a definitive guide to diagnosing shoulder conditions for trainees, general practitioners, physiotherapists, orthopaedic surgeons and radiologists with an interest in shoulder pathology. It comes at a time when the knowledge regarding shoulder conditions has vastly improved, with the shoulder sub-speciality growing at a rapid pace in terms of practitioner numbers, procedures and evidence base.

It is unclear, in most circumstances, which single clinical test or indeed radiological investigation is the best for diagnosing a particular condition. In fact, the diagnosis of a particular shoulder condition rests on the four sub-components of clinical history, conventional examination, special tests and radiological investigations. It is often the case that all these sub-components are to be used in conjunction with each other as “clusters” rather than in isolation. This forms the basis of the cluster approach, which is the key concept for the title and content of this book. This book presents a practical guide for diagnosis, written by a select group of surgeons and physiotherapists with a special interest in shoulder pathologies, who have painstakingly extracted these relevant clusters for each shoulder conditions from clinical experience and published work.

About the Author

Puneet Monga is a UK-based Consultant Orthopaedic Shoulder Surgeon at the Wrightington Hospital, and a Honorary Senior Lecturer at the University of Salford and Edge Hill University.

Lennard Funk is a UK-based Consultant Orthopaedic Shoulder Surgeon at the Wrightington hospital, and a Honorary Professor at the University of Salford.

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Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases Softcover reprint of hardcover 3rd ed

October 10, 2017

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The third edition of this book has been comprehensively rewritten and rearranged. In addition to the bone and joint diseases described in the two earlier editions, it now encompasses hitherto unpublished novel applications of pinhole scanning to the diagnosis of a broader spectrum of skeletal disorders. The book has been considerably expanded to discuss five new themes and is complemented by the addition of some 90 recently acquired cases.

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Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases: Including Gamma Correction Interpretation 4th ed

October 10, 2017

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In this fourth edition of Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases, the text has been thoroughly amended, updated, and partially rearranged to reflect the latest advances. In addition to discussing the role of pinhole imaging in the range of disorders previously covered, the new edition pays detailed attention to the novel diagnostic use of gamma correction pinhole bone scan in a broad spectrum of skeletal disorders, including physical, traumatic, and sports injuries, infectious and non-infectious bone diseases, benign and malignant bone tumors, and soft tissue diseases. A large number of state of the art pinhole scans and corroborative CT, MRI, and/or ultrasound images are presented side by side. The book has been enlarged to encompass various new topics, including occult fractures; cervical sprain and whiplash trauma; bone marrow edema; microfractures of trabeculae; evident, gaping, and stress fractures; and differential diagnosis. This new edition will be essential reading for practitioners and researchers in not only nuclear medicine but also radiology, orthopedic surgery, and pathology.

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Clavicle Injuries: A Case-Based Guide to Diagnosis and Treatment 1st ed. 2018 Edition

October 5, 2017

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This is the first book of its kind to specifically cover all aspects of clavicle injury management, from anatomy and biomechanics to anesthesia and radiology, with the bulk of the chapters presenting current treatment strategies, both operational and otherwise. The clavicle is the most frequently injured bone in the human body, but despite the frequency of injury, there is a remarkable breadth of treatment options and controversy regarding operative and non-operative treatment, with intramedullary fixation and plating techniques both having avid supporters. Each chapter presents expert opinion and relies on biomechanics, anatomy, radiography, evidence-based medicine and outcome studies to reach their conclusions. Technique chapters include illustrative case material, demonstrating a variety of presentations and outcomes. Pediatric and sports-related clavicular injuries are also highlighted, as are complications, for a well-rounded, comprehensive resource.

Before now, a text focusing solely on injuries to the clavicle may have seemed like an impossibility. However, given recent reinvestigation into outcomes and emerging concepts in management, Clavicle Injuries stands as the go-to resource for currently techniques for diagnosis and management of these common injuries for orthopedic and emergency surgeons as well as sports medicine specialists.

About the Author

Gordon I. Groh, MD, Asheville Orthopedics, Asheville, NC, USA

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Orthopedic Nuclear Medicine 2nd ed. 2017 Edition

September 26, 2017

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This book, now in a revised and updated second edition, offers a comprehensive overview of the state of the art in orthopedic nuclear medicine, including the impressive recent advances in the field and the diagnosis of under-recognized conditions on the basis of their imaging patterns. The opening chapters acquaint the reader briefly with anatomic, physiologic, pathologic, and technical concepts crucial to a sound understanding of orthopedic nuclear medicine and its utilization in clinical practice. The imaging diagnosis of skeletal infections, trauma, vascular disorders, metabolic and neoplastic bone diseases, soft tissue calcifications, and joint disorders is then explained in detail. Two entirely new chapters, on bone marrow imaging and hybrid imaging of bone diseases, have been added to this edition. A separate chapter is devoted to the use of radionuclides for the treatment of bone and joint disorders. The book is richly illustrated and amply documents the effectiveness of nuclear medicine in diagnosing bone disease. It will prove invaluable to all with an interest in diagnostic and therapeutic orthopedics, including orthopedists, radiologists, rheumatologists, pediatricians, podiatrists, other clinicians, and all nuclear and molecular imaging professionals.

“..it is one of the best nuclear medicine textbooks and the most complete presentation of the role of nuclear medicine in orthopedics …This book addresses a difficult topic in nuclear imaging that is often insufficiently covered ba many general textbooks in the field. ..a must have book for all professionals dealing with orthopedic problems….(Michael J. Blend, Radiology, Vol. 239, April 2006).

“This is a fine book that encompasses every aspect of bone physiopathology related to nuclear medicine in orthopaedic surgery. Nicely illustrated and well presented, this book offers comfortable and interesting reading and brings an in-depth insight on the mechanisms of action, the pathology and the pharmacology of the imaging molecules. … This volume should be available to every orthopaedic surgeon and trainee.” (C. Delloye, Acta Orthopaedica Belgica, Vol. 70(6), 2004)

“Despite the emergence of new imaging methods, nuclear medicine and in particular, osseous scintigraphy, preserves a very particular place in osteoarticular exploration. A.H. Elgazzar performs an update of the various applications in this field. … the author has the requisite merit to produce a synthetic work on the entire gamut of nuclear medicine applications in osteoarticular pathology, intended for a large audience from the point of view of specialists as well as those with some experience.” (L. Balabaud, European Journal of Orthopaedic Surgery & Traumatology, Vol. 16, 2006)

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Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases: Including Gamma Correction Interpretation 5th ed. 2017 Edition

September 26, 2017

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In the fifth edition of this highly successful book, the author once again aims to equip the reader with up-to-date information that will facilitate accurate diagnosis of bone and joint diseases by means of combined use of scintigraphy and radiology. Two entirely new chapters have been added, one on the use of 18F-NaF PET/CT and the other on gamma correction scan diagnosis of bone trabecular microfracture and microcontusion as well as bone edema and hemorrhage. Further topics covered for the first time include enthesopathies, myositis, soft tissue diseases, cryptic bones, and differential diagnosis. Individual chapters have been updated and rearranged to reflect the latest advances in imaging diagnosis. As before, a vast number of state of the art gamma correction pinhole bone scans and corroborative conventional radiographs and CT, MRI, and/or ultrasound images are presented side by side. In this new edition, extension of the application of gamma correction to other imaging methods such as MRI and CT and the solution of the halation problem are necessarily addressed. This fifth edition of Combined Scintigraphic and Radiographic Diagnosis of Bone and Joint Diseases will be essential reading for practitioners and researchers in nuclear medicine, radiology, orthopedic surgery, pathology, anatomy, and imaging sciences at large.

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Surgical Atlas of Sports Orthopaedics and Sports Traumatology

September 22, 2017

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“This is probably the best atlas/textbook on sports orthopaedics available. … I recommend this book to traumatologists and orthopedic surgeons, residents, and students. It is also helpful to sports and rehabilitation specialists.” (Joseph J. Grenier, Amazon.com, May, 2015)

“This surgical atlas on sports orthopedics is divided into anatomic areas, detailing the most common operations for each. … The appropriate audience is practicing sports medicine orthopedic surgeons as well as trainees … . The illustrations are consistently top notch, and the book covers a wide range of sports medicine operative problems … .” (Scott A. Magnes, Doody’s Book Reviews, April, 2015)

From the Back Cover

This atlas depicts and describes the newest arthroscopic and open techniques for dealing with sports orthopaedic injuries and problems. More than 75 surgical procedures are presented step by step with the aid of superb illustrations. Arthroscopic views, artist drawings, X-rays, and clinical and operative photographs are all included to demonstrate exactly how each procedure should be performed. Individual sections are devoted to the shoulder, elbow, pelvis/hip, knee, and ankle/foot. By offering complete illustrated guidance on the surgical management of sports-related injuries, the Surgical Atlas of Sports Orthopaedics and Sports Traumatology will prove invaluable to both novice and experienced surgeons.

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Biomarkers in Bone Disease (Biomarkers in Disease: Methods, Discoveries and Applications) 1st ed. 2017 Edition

September 15, 2017

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There are many conditions that affect the skeletal system. On a worldwide basis, osteoarthritis alone affects 10%-15 percent of those over 60 years of age and in some countries more than 30-50% of postmenopausal women will have osteopenia or osteoporosis. With the increasing ageing population, maintaining skeletal health is particularly important. Fractures in the aged, for example, can lead to premature deaths. It is therefore imperative that appropriate use is made of conventional, new and emerging biomarker platforms. Biomarkers in Bone Disease embraces a holistic approach by combining information on different conditions that affect the skeletal system and the use of biomarkers. Biomarkers are described in terms of conventional, new and emerging analytes, techniques, platforms and applications. It covers the latest knowledge, trends and innovations. New platforms are described which combine advances in biomedical sciences, physics, computing and chemistry.

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Orthopedics

Pediatric Femur Fractures: A Practical Guide to Evaluation and Management 1st ed. 2016 Edition

September 10, 2017

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Bringing together the many considerations and complexities surrounding the management pediatric femur fractures, this up-to-date, comprehensive book discusses all aspects of these common but challenging injuries, where the treatment strategies are rapidly changing and which have the potential for complications and less than ideal outcomes. Because there may be multiple acceptable treatment approaches to a given fracture, we sought to review the full spectrum of therapeutic modalities. The entirety of the pediatric femur is considered, including femoral head and neck fractures, diaphyseal, physeal and epiphyseal fractures, and intra-articular fractures of the distal femur. Opening with chapters on development and anatomy as well as radiological evaluation, each fracture type-specific chapter discusses the indications and contra-indications, advantages and disadvantages, technical principles and published outcomes associated with each of the accepted techniques, from casting and traction to external and internal fixation. Concluding chapters discuss pathological fractures and the evaluation and management of complications. By channeling the expertise of a broad and accomplished group of authors with extensive experience in both researching and treating pediatric femur fractures, Pediatric Femur Fractures provides caregivers with the most complete and reliable resource when faced with any of the many types of this challenging injury.

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