Category: Oncology

Combinational Therapy in Triple Negative Breast Cancer 1st Edition

Combinational Therapy in Triple Negative Breast Cancer 1st Edition

Combinational Therapy in Triple Negative Breast Cancer discusses TNBC at the molecular level from a holistic approach, focusing on combinational strategies targeting various pathways involved in this specific cancer type. Using a monotherapy for the treatment of cancer, especially high-grade tumors like TNBC, is mostly worthless due to the inherent genetic instability of tumor cells to develop intrinsic and acquired resistance. Combination therapy presents more, or at least the same, effectiveness with lower doses of every single agent and decreases the likelihood of chemoresistance, making it essential to understand for multiple therapy options.

The book is a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of combinational therapies to treat triple negative breast cancer.

Presents up-to-date and cutting-edge knowledge of Triple negative breast cancer (TNBC) biology, clinical aspects and treatment options
Discusses novel targets and pathways involved in TNBC
Provides insights and approaches for future research on TNBC

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Gynecologic Oncology Handbook: An Evidence-Based Clinical Guide 2nd Edition

Gynecologic Oncology Handbook: An Evidence-Based Clinical Guide 2nd Edition

Now in its second edition, Gynecologic Oncology Handbook: An Evidence-Based Clinical Guide has been thoroughly updated to include the latest advances in surgical techniques, chemotherapy protocols, AJCC 8th Edition staging criteria, and much more. This current edition contains illustrations that reinforce key concepts, algorithms for diagnostic techniques, and tables to guide you in optimal disease management.

The handbook covers the spectrum of gynecologic oncology from seminal studies to guide the oncologist, to the essential workup for the Obstetrician/Gynecologist and related clinician. This handbook can be carried by the practitioner on the ward or in the clinic. It includes necessary details on gynecologic cancer screening and treatment regimens for preinvasive disease, to staging and management of all the gynecologic cancers such as cervical cancer, ovarian cancer, uterine cancer, vulvar cancer, vaginal cancer, and gestational trophoblastic disease. It highlights evidence-based best practices for managing these cancers, hereditary cancer syndromes, for surgical care, and for all adjuvant therapies including chemotherapy, radiation therapy, targeted therapies, and immunotherapies. Detailed sections on survivorship care, palliative care, as well as managing reproductive function and other comorbid medical conditions make this a ‘one-stop shop’ for navigating all clinical aspects and effects of gynecologic cancer.

Featuring new and important clinical study references, medical comorbidity algorithms, directed gynecologic cancer workups and treatments, numerous tables and easy-to-reference illustrations, the Gynecologic Oncology Handbook, 2nd Edition is the ultimate quick reference for the clinical management of all gynecologic malignancies and related conditions.

Key Features:

  • Covers all fundamentals of gynecologic oncology including workup, staging, surgical management, chemotherapy and radiation therapy treatment, comorbidity diagnosis and management, and background study data
  • Provides Gynecologic Oncology Referral Parameters, Performance Status Scales, Adverse Event Grading, RECIST evaluation criteria, chemotherapy protocols, statistics, and other useful formulas.
  • Includes clinical study references, medical comorbidity algorithms, directed workups, and treatment guidelines
  • Includes digital access to the eBook

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The Peripheral T-Cell Lymphomas 1st Edition

The Peripheral T-Cell Lymphomas 1st Edition

THE PERIPHERAL T-CELL LYMPHOMASProvides a comprehensive look at Peripheral T-Cell lymphomas, including the group’s unique geographic distribution, underlying genetics, and novel treatments

Peripheral T-Cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represent 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat.

For the first time in a single volume, The Peripheral T-Cell Lymphomas presents a comprehensive survey of this complex and rare group of blood cancers. Featuring contributions from an international team of leading authorities in the various aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource:

  • Covers the biological basis, epidemiology, classification, and treatment of PTCL
  • Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL
  • Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation
  • Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations
  • Features contributions from the Chairs The T-Cell Lymphoma Forum: the world’s largest meeting focused on PTCL

Reflecting the unique epidemiology and genetic diversity of the PTCL, The Peripheral T-Cell Lymphomas is an indispensable source of data, insight, and references for the medical community, particularly oncologists and hematologists in both training and practice.

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The MD Anderson Manual of Medical Oncology, Fourth Edition 4th Edition

The MD Anderson Manual of Medical Oncology, Fourth Edition 4th Edition

Expert, hands-on guidance for the practicing oncologist―from the leader in the field of cancer management―completely updated to reflect the latest advances

A Doody’s Core Title for 2022!

Comprehensive and authoritative, The MD Anderson Manual of Medical Oncology delivers everything you need to accurately diagnose and effectively treat a wide range of cancers―including leukemia, lymphoma, myeloma, lung and breast cancer, genitourinary carcinoma, melanoma, and sarcoma.

This unmatched resource emphasizes practical, actionable steps to cancer treatment, providing “to the point” recommendations, chapter summary boxes, tables, charts, expert opinion and patient education boxes, practice tips, cases, and prescriptive advice. The new format of this updated edition quickly guides you to the topic, the affiliated relevant chapter, new findings affecting clinical practice, and reference/evidence.

This fourth edition features:

NEW Q&A, cases, patient education information, and expert advice
Expanded coverage of immunotherapy treatment―written by the 2018 Nobel Prize-winner for immunology
Access to continually updated online content
A comparative table with guidelines from the European Society of Medical Oncology and the American Society of Clinical Oncology
An emphasis on recent developments in precision medicine and immunotherapies
Plus important NEW chapters on:
Cord blood transplant
Haploidentical cell transplantation
Cellular therapy in allogeneic hematopoietic cell transplantation
Pediatric cancers
Molecular biomarkers and cancer
Immune-oncology
Targeted therapies in cancer
Applied biostatistics
Oncocardiology
Pulmonary complications of cancer associated thrombosis

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Counseling About Cancer: Strategies for Genetic Counseling 4th Edition

Counseling About Cancer: Strategies for Genetic Counseling 4th Edition

Counseling About Cancer
A key resource for all genetic counselors and other healthcare providers, this comprehensive reference has been completely updated and reorganized for its fourth edition

Over 50 hereditary cancer predisposition genes have now been identified. Genetic testing can be a powerful tool in assessing individual cancer risk and creating robust medical plans, but can also be a complex process, with personal and familial factors carrying real emotional weight. As such, genetic counseling for patients and their families during the process of genetic testing is critical.

Counseling about Cancer: Strategies for Genetic Counseling is the only comprehensive resource available for clinicians who want to understand and apply these dimensions of patient care. This updated and reorganized edition provides detailed information designed to be incorporated in a variety of clinical and health-care contexts. Updated with the latest guidance and research, it promises to continue as the indispensable guide to this challenging subject.

Readers of the fourth edition of Counseling about Cancer will also find:

New chapters analyzing pediatric cancer syndromes, genetic testing technology, and more
Increased focus on gynecological cancer syndromes and related genes
Detailed case studies to reinforce themes of each chapter
Counseling about Cancer is a useful reference for genetic counselors and other healthcare providers looking to familiarize themselves with best practices of patient counseling and care.

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Fast Facts: Bladder Cancer

Fast Facts: Bladder Cancer

Fast Facts: Bladder Cancer

Our understanding of the biology of bladder cancer has advanced remarkably since the second edition of ‘Fast Facts: Bladder Cancer’ was published in 2006. Five new immunotherapies targeting the PD-1 axis were approved in 2016 and 2017 for the treatment of advanced bladder cancer, reflecting this transformative explosion in knowledge about the biology of the disease. This new era of targeted treatment offers hope to patients, particularly those with advanced disease. However, for clinicians it means a lot to understand in terms of how these immunotherapies are integrated into the treatment paradigm. Who they are suitable for? When are they best used? What is the optimal sequence of treatments for individual patients

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Oncology Board Review, Third Edition

Oncology Board Review, Third Edition: Blueprint Study Guide and Q&A

Oncology Board Review, Third Edition

Now in its third edition of  this medical book, Oncology Board Review: Blueprint Study Guide and Q&A is designed to help you prepare for the American Board of Internal Medicine (ABIM) Medical Oncology Certification Exam. This comprehensive print + digital resource has been revised to include new treatment regimens, clinical guidelines, and other advancements impacting the field as well as updated board-style Q&A. Dedicated sections cover hematological malignancies and solid tumors with a templated chapter approach highlighting epidemiology, etiology and risk factors, diagnostic criteria, staging, signs and symptoms of the disease, prognostic factors, indications for treatment, and special considerations. Later sections address other topics found on the exam, including cancer genetics and tumor biology, supportive and palliative care, bone marrow transplantation, and biostatistics. With more than 240 practice questions, detailed rationales, and a convenient print + digital package, Oncology Board Review gives you the tools to study your way and the confidence to pass the first time!

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Key Features:

  • Aligns with the latest ABIM Medical Oncology Certification Exam blueprint
  • Provides a comprehensive yet concise review of all hematologic malignancies and solid tumors
  • Covers anticancer therapies, clinical research methodology, survivorship and palliative care, and more areas found on the exam
  • Revised to include new treatment recommendations and FDA approvals
  • Includes end-of-chapter assessment questions with detailed rationales – a total of more than 240 questions throughout
  • Content available digitally via ExamPrepConnect for study on the go

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Textbook of Clinical Trials in Oncology

Textbook of Clinical Trials in Oncology

Textbook of Clinical Trials in Oncology

There is an increasing need for educational resources for statisticians and investigators. Reflecting this, the goal of this book is to provide readers with a sound foundation in the statistical design, conduct, and analysis of clinical trials. Furthermore, it is intended as a guide for statisticians and investigators with minimal clinical trial experience who are interested in pursuing a career in this area.

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The advancement in genetic and molecular technologies have revolutionized drug development. In recent years, clinical trials have become increasingly sophisticated as they incorporate genomic studies, and efficient designs (such as basket and umbrella trials) have permeated the field. This book offers the requisite background and expert guidance for the innovative statistical design and analysis of clinical trials in oncology.

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Fundamentals of Radiation Oncology 3rd Edition

Fundamentals of Radiation Oncology 3rd Edition

Fundamentals of Radiation Oncology: Physical, Biological, and Clinical Aspects, Third Edition continues to provide current, concise, and a readily available source of clinical information for busy practicing radiation oncologists.

The medical book consists of 26 chapters, divided into four parts:

Part I describes the basic science of radiation oncology, with discussions of radiation physics, radiation protection, and radiation biology, as well as molecular biology.

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Part II describes techniques and modalities of radiation oncology including brachytherapy, intensity-modulated radiation therapy (IMRT), stereotactic radiotherapy (SRS), stereotactic body radiation therapy (SBRT), and proton therapy. Significant recent advances made in the areas of immunotherapy and combined modality therapy; as such, these chapters have also been added to this new edition.

Part III describes the clinical science of radiation oncology including risk factors, symptoms/signs, and investigations needed for the cancer diagnosis and up-to-date treatment recommendations in accordance with the new AJCC staging system. In addition, radiation treatment techniques, with an emphasis on IMRT, have been expanded to all the chapters. Also included in this version of the book is a chapter on benign diseases. Updated annotated bibliographies of latest landmark studies providing evidence-based rationale for the recommended treatments are presented at the end of each chapter.

Part IV describes palliative radiation treatments to improve the quality of life for cancer patients and the management of side effects from radiation treatment. This medical book is a must-have for all radiation oncology residents, radiation oncologists and all professionals engaged in the care of cancer patients.

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