Functional Urologic Surgery in Neurogenic and Oncologic Diseases: Role of Advanced Minimally Invasive Surgery (Urodynamics, Neurourology and Pelvic Floor Dysfunctions)

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This book offers a comprehensive guide to state-of-the-art techniques in functional urologic surgery that minimize functional damage to the urinary tract and are of particular value in patients with oncologic or neurogenic diseases. It describes the main minimally invasive surgical techniques currently available step by step, while also offering guidance on indications and how to select appropriate surgical devices to achieve specific oncological and functional outcomes. Further, the book presents data from relevant case series, documenting the favorable functional and oncologic results achieved with these techniques and devices as well as the low associated morbidity and positive impacts on quality of life. Lastly, it offers advice on preoperative assessment and postoperative care, and presents specific diagnostic algorithms of value in daily clinical practice. The contributing authors represent an international mix of respected experts carefully selected for their knowledge of the topics discussed.

This book offers a comprehensive guide to state-of-the-art techniques in functional urologic surgery that minimize functional damage to the urinary tract and are of particular value in patients with oncologic or neurogenic diseases. It describes the main minimally invasive surgical techniques currently available step by step, while also offering guidance on indications and how to select appropriate surgical devices to achieve specific oncological and functional outcomes. Further, the book presents data from relevant case series, documenting the favorable functional and oncologic results achieved with these techniques and devices as well as the low associated morbidity and positive impacts on quality of life. Lastly, it offers advice on preoperative assessment and postoperative care, and presents specific diagnostic algorithms of value in daily clinical practice. The contributing authors represent an international mix of respected experts carefully selected for their knowledge of the topics discussed.

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Minimally Invasive Surgical Oncology: State-of- the-Art Cancer Management

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Minimally Invasive Surgical Oncology is aimed at the minimal invasive surgeon as well as at the general surgeon and surgical trainee who wish to explore this field. It covers disciplines like gastroenterology, gynecology, urology, thoracic and pediatrics and builds bridges to oncologists and internal medicine. It gives a state-of-the art overview and perspectives for future developments and research as well. The book serves as an operative guide for a new generation of surgeons and offers the extraordinary feature being a text book, an operative atlas and a quick reference guide as well. The reader is provided with a tool in hand which synthesizes the latest knowledge in traditional therapies like chemotherapies and gives a comprehensive overview how to proceed in treating a cancer patient using minimal access techniques.

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Surgical Oncology (Oxford Specialist Handbooks in Surgery) Poc Edition

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How should surgeons deal with cancer patients? The cornerstone of effective treatment is a multidisciplinary collaboration between many specialists in which surgeons are not only concerned about operative accessibility and technique, but rather have a deep understanding of the fundamental biology of the malignancy they are dealing with and appreciate the reach of multi-modal treatment.

This handbook is a practical reference for today’s surgeons who actively manage cancer patients in both the acute and out-patient setting. It covers all the key areas, from initial presentation and diagnosis, investigation and staging, to active discussion in collaborative multidisciplinary cancer network meetings, operative management, post-operative care, and long term surveillance and palliation. Drawing together all the varied guidelines and source materials that form the basis of this complex subject, it is the first surgical oncology text that provides instant access to detailed clinical algorithms and operative techniques covering the wide range of cancers that general surgeons encounter, from GI tract to breast and endocrine cancers. Consistently source from current evidence based guidelines wtih a concise summary of underlying pathology and molecular biology, Surgical Oncology will enable the reader to knowledgeably manage cancer patients from initial assessment to long term surveillance. It is an essential accompaniment for all higher surgical trainees from MRCS to the exit FRCS and EBSQ exams, and will be particularly useful for trainees rotating between surgical subspecialties, as well as having wide appeal to other members of the multidisciplinary team.

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Oxford Guide to CBT for People with Cancer (Oxford Guides to Cognitive Behavioural Therapy) 2nd Edition

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Cognitive Behaviour Therapy (CBT) has established itself as the psychological treatment of choice for many conditions. It offers a brief, convincing, common sense approach to the emotional problems faced by people with cancer, and there is considerable evidence for its effectiveness. Using a cognitive behavioural model to understand reactions to cancer, the authors present cognitive, behavioural, emotional and interpersonal interventions to help people adjust to the threat to their life and their view of themselves. Case examples illustrate how these techniques are used to reduce anxiety and depression, induce a fighting spirit, teach effective coping skills and develop open communication between patients and their partners.

Now part of the Oxford Guide to Cognitive Behavioural Therapy series, this new edition has been updated in light of new clinical and research findings in the fields of psycho-oncology and cognitive behaviour therapy over the last 10 years. Mental health professionals working in oncology and health care professionals interested in psychological management will find this a useful source for psychological techniques that can be applied in a busy clinical setting.

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Implementation of Lung Cancer Screening: Proceedings of a Workshop

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The public health burden from lung cancer is substantial: it is the second most commonly diagnosed cancer and the leading cause of cancer-related deaths in the United States. Given the individual and population health burden of lung cancer, especially when it is diagnosed at later stages, there has been a push to develop and implement screening strategies for early detection. However, many factors need to be considered for broad implementation of lung cancer screening in clinical practice. Effective implementation will entail understanding the balance of potential benefits and harms of lung cancer screening, defining and reaching eligible populations, addressing health disparities, and many more considerations.

In recognition of the substantial challenges to developing effective lung cancer screening programs in clinical practice, the National Academies of Sciences, Engineering, and Medicine held a workshop in June 2016. At the workshop, experts described the current evidence base for lung cancer screening, the current challenges of implementation, and opportunities to overcome them. Workshop participants also explored capacity and access issues; best practices for screening programs; assessment of patient outcomes, quality, and value in lung cancer screening; and research needs that could improve implementation efforts. This publication summarizes the presentations and discussions from the workshop.

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Natural Products and Cancer Drug Discovery (Cancer Drug Discovery and Development)

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From the Back Cover

Osteosarcoma 1st ed

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The Drug Development Paradigm in Oncology: Proceedings of a Workshop

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Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system responds to cancer. This influx of research has led to an increasing number and variety of therapies in the drug development pipeline, including targeted therapies and associated biomarker tests that can select which patients are most likely to respond, and immunotherapies that harness the body’s immune system to destroy cancer cells. Compared with standard chemotherapies, these new cancer therapies may demonstrate evidence of benefit and clearer distinctions between efficacy and toxicity at an earlier stage of development. However, there is a concern that the traditional processes for cancer drug development, evaluation, and regulatory approval could impede or delay the use of these promising cancer treatments in clinical practice. This has led to a number of efforts—by patient advocates, the pharmaceutical industry, and the Food and Drug Administration (FDA)—to accelerate the review of promising new cancer therapies, especially for cancers that currently lack effective treatments. However, generating the necessary data to confirm safety and efficacy during expedited drug development programs can present a unique set of challenges and opportunities.

To explore this new landscape in cancer drug development, the National Academies of Sciences, Engineering, and Medicine developed a workshop held in December 2016. This workshop convened cancer researchers, patient advocates, and representatives from industry, academia, and government to discuss challenges with traditional approaches to drug development, opportunities to improve the efficiency of drug development, and strategies to enhance the information available about a cancer therapy throughout its life cycle in order to improve its use in clinical practice. This publication summarizes the presentations and discussions from the workshop.

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Tumors and Cancers: Central and Peripheral Nervous Systems (Pocket Guides to Biomedical Sciences) 1st Edition

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Tumors and cancers are insidious diseases characterized by an abnormal growth of cells that extend beyond their usual boundaries and disrupt the normal functions of affected organs. Forming the first of the four volumes devoted to tumors and cancers, this volume focuses on the central and peripheral nervous systems. Each chapter presents a state of the art summary of tumor/cancer of a particular type in relation to its definition, biology, epidemiology, disease mechanism/pathogenesis, clinical signs, diagnosis, treatment and prognosis.

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Reflectance Confocal Microscopy of Cutaneous Tumors, Second Edition 2nd Edition

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Reflectance confocal microscopy enables lesions in skin to be examined without excision, but with improved diagnostic accuracy, assessment of dermoscopic-histologic correlation, assessment of surgical margins, as well as speed and convenience for the physician and patient. This extensively enlarged and updated text reviews the current and future state of the art for those involved with the diagnosis and treatment of skin tumors, with a greatly increased amount of material on the expected normal patterns of skin throughout life and on non-melanocytic tumors.

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