Category: Oncology

Oxford American Handbook of Oncology (Oxford American Handbooks of Medicine) 2nd Edition

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The Oxford American Handbook of Oncology is the essential reference for medical students, residents, and clinical oncologists seeking a current, portable resource on the delivery of sophisticated cancer care. Chapters focus on the immediate information needs in clinical decision making including treatment choices. Algorithms, best practice guidelines, highlighted tables, and targeted lists of landmark references enhance the concise text. For the second edition biologic therapies and therapeutic regimens and options and clinical trial information have been rigorously updated throughout.

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Breast Cancer: Molecular Genetics, Pathogenesis, and Therapeutics (Contemporary Cancer Research)

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“Extensive information about a multitude of topics associated with breast cancer genetics and possible causative factors in breast cancer progression is provided. This book also includes both a generalized overview of breast cancer therapeutics as well as the most current thoughts on experimental treatment ideas. The chapter, “Hereditary Breast Cancer Genes,” is extremely well covered…the chapter on psychological issues surrounding genetic testing is particularly strong because of its use of case examples. The discussion of surgical and chemotherapeutic approaches is thorough and cohesive…this is an excellent resource for researchers in the field…This book stands out in that it provides a comprehensive approach to the relevant advances in breast cancer research as they apply to therapeutics, an approach that has been missing in the recent literature.” -Doody’s Health Sciences Book Review Journal

“. . .successfully steers between the impossibility of a comprehensive book on all aspects of breast cancer and the undesirability of a quasi-random selection of isolated topics. The chapters are clearly written, succinct, and eminently readable for the physician as well as the molecular biologist. The book is well referenced and summarizes a wealth of data in a straight-forward and digestible manner. . .For the research scientists, epidemiologists, and clinician, this book will serve as an interesting and useful guide to the coming era.”-The New England Journal of Medicine

“The book has 25 chapters divided into 3 sections dealing with etiology and cancer genes, diagnosis, therapeutics and drug resistance, and environmental risk factors. Each chapter is densely packed with data. . .Lerman and Peshkin have written a very important chapter about the psychosocial aspects of genetic testing. Several case reports help make in the information relevant. . .The book will be extremely helpful to the graduate student and laboratory investigator who wants to have a single source with good references.”-Oncology

“It represents a state-of-the-art review of current and future research directions in breast cancer treatment,…The references are extensive…the translational provides relevant clinical correlations whenever possible. Another strength is that most chapters conclude with a summary of the salient points….provides important information for pathologists who are heavily involved with breast cancer.”-Modern Pathology

“…an exhaustively encyclopedic text on the topic, focusing on the research of its development, causes and treatments. It is well written and concise, and extensively covers all issues that research scientists and medical consultants might encounter in the study of breast cancer.” -The Journal of Family Practice

“…an excellent state-of-the-art summary of breast cancer research and treatment.”-Anticancer Research

“…The editor has brought together an impressive collection of specialists to provide a broad range of subjects. The book is extensively referenced and individual chapters are thorough and detailed in the coverage of the topics. In this respect, the book meets its aims admirably….this is a good reference book and does have have something for clinicians as well as basic scientists, It will be a useful source of information for those involved in breast cancer research and treatment.”- Human Genetics

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From the Back Cover

Breast, Endocrine and Surgical Oncology (Surgery: Complications, Risks and Consequences)

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From the Back Cover

Radiation Therapy for Extranodal Lymphomas 1st ed. 2017 Edition

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This book is devoted to sharing the knowledge and experience of expert radiation therapy (RT) for extranodal lymphomas. For that purpose, the authors provide clinical-pathological information, precise RT techniques, and treatment results, i.e., disease control and survival, of all extranodal lymphomas.

Over the past 10 years, specific techniques have been updated, from 3-dimensional conformal RT to intensity modulated RT / volumetric-modulated arc therapy. Precise targeting such as image-guided RT and active breathing control are now capable of treating lymphoma lesions that shift with respiration or peristalsis.

This book, serving as a guide, provides the necessary knowledge for radiation oncology, practice, and planning involving the RT techniques of treating extranodal lymphomas. In addition, it equips oncologists, hematologists, and medical oncologists to refer patients with extranodal lymphomas to radiation oncologists for appropriate treatment in a timely manner. Therefore this volume will greatly benefit all oncologists, including radiation and medical oncologists, as well as hematologists.

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Innovation of Diagnosis and Treatment for Pancreatic Cancer 1st ed. 2017 Edition

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This collection of chapters describes in detail the latest insights into the evaluation of resectability and neoadjuvant therapy to pancreaticoduodenectomy and distal pancreatectomy for pancreatic cancer. Shedding light on immunotherapy and gene therapy, this volume comprehensively covers treatments and procedures for the disease, allowing surgeons and trainees to gain an overview and explore innovative treatments. It also provides information on various cases using tools such as endoscopic ultrasound, MDCT, PET for diagnosis and laparoscopy and robotic resection methods.
Edited and authored by pioneering professionals, Diagnosis and Treatment for Pancreatic Cancer is a valuable resource for gastroenterologists, medical oncologists, surgical oncologist and general surgeons interested in treatment of pancreatic cancer care.

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Cancer and Chemoprevention: An Overview 1st ed. 2017 Edition

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This book focuses on the most recent, relevant, comprehensive and significant advances in cancer and chemo prevention. It broadly discusses cancer, its hallmarks and classification, molecular mechanisms of outbreak, contributing factors, role of oxidative stress, inflammatory mediators and evading apoptosis, which leads to the progression of disease.

Though modern medicine has left us with no option to treat this deadly disease due to drawbacks associated with conventional treatment – like its non-targeted nature, drug resistance, varied organ toxicities and unaffordability – chemoprevention offers a viable therapeutic window.

Given chemoprevention’s importance in the present scenario, the book highlights various chemo preventive strategies currently used in the management of cancer; a selection of novel chemo preventive agents used at clinics and in the pre-clinical stage; hurdles to effective chemoprevention; future prospects and the road ahead. It offers a valuable guide for all graduate students and researchers seeking information on cancer and chemoprevention in general, irrespective of the specific type/pathways involved in its onset.

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Dendritic Cells in Cancer 2009th Edition

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It covers all aspects of DC generation, function, survival and antitumor activity in the tumor environment both in vivo and in experimental in vitro systems. The goal in focusing on a spectrum of issues related to DC in cancer is to provide an extensive and expansive review rather than a collection of independent analyses from different authors.

Specific topics to be covered include analysis of DC behavior in the tumor microenvironment, including endogenous and exogenous DC, multiple DC populations, molecular pathways responsible for DC dysfunction, tumor-derived factors altering DC polarization and activation, mechanisms of DC alterations, and the role of DC in tumor escape from immune recognition and elimination. Furthermore, additional chapters provide extensive analysis of the consequences of cancer therapy on the DC system and how aging impacts DC function in the tumor microenvironment. Finally, chapters are included examining strengths and pitfalls of current methodologies for generating DC from cancer patients for therapeutic purposes and on the role of tumor-mediated modulation of the DC system in cancer immunotherapy.

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Ovarian Cancer: Second Edition (Cancer Treatment and Research) 2nd ed. 2010 Edition

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Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumor-specific therapeutics.

Ovarian carcinogenesis, invasion, and metastatic dissemination require a complex cascade of interrelated genetic, molecular, and biochemical events that regulate the neoplastic transition of normal ovarian surface epithelium.

This updated second edition includes exciting new advances in ovarian cancer detection and treatment and provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A more detailed understanding of these processes may ultimately translate into the development of novel approaches for the detection and control of ovarian cancer.

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Cancer Cytogenetics: Chromosomal and Molecular Genetic Abberations of Tumor Cells 3rd Edition

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The preeminent book on cancer cytogenetics—now in a valuable new edition

Like its successful predecessors, Cancer Cytogenetics, Third Edition continues to offer authoritative coverage of neoplastic processes at the chromosomal level of genomic organization. Now updated and expanded, this new edition includes detailed information on the most recent advances in the field, incorporating a vast amount of new cytogenetic as well as molecular genetic data from the latest basic and clinical investigations.

Edited by two leading authorities, who are now aided by a panel of internationalexperts, this new edition has been updated to include:

  • Greatly expanded coverage of solid tumors
  • Enhanced coverage of acute and chronic myeloproliferative disorders
  • The latest findings on acute and chronic lymphoproliferative disorders

Cancer Cytogenetics, Third Edition is a valuable resource for researchers in a wide range of fields, including cytogenetics, medical and molecular genetics, cellular and molecular biology, oncology, and hematology. With its complete coverage of thecytogenetic mechanisms underlying neoplasia, and always with a keen eye on the clinical consequences of the various acquired genetic aberrations, this text will alsobe an indispensable reference for all clinicians involved in the diagnosis and treatment of cancer patients.

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Cancer Biology and the Nuclear Envelope: Recent Advances May Elucidate Past Paradoxes (Advances in Experimental Medicine and Biology)

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“Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE  is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer.”

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