Preeclampsia: Basic, Genomic, and Clinical

Preeclampsia: Basic, Genomic, and Clinical (Comprehensive Gynecology and Obstetrics)

Preeclampsia: Basic, Genomic, and Clinical

This volume is an excellent guide that comprehensively illustrates hypertensive disorders of pregnancy, especially preeclampsia, in both the basic and clinical aspects.

Preeclampsia is a pregnancy-specific multi-organ disorder and a leading cause of maternal and neonatal mortality. The pathophysiology of pregnancy-specific disorders was long unknown, but recently many new findings have been reported from the point of view of pathophysiology. Furthermore, this complication of pregnancy, especially preeclampsia, is a potent risk factor for chronic conditions such as cardiovascular disease, diabetes mellitus, kidney disease, and hypertension.

The book is composed of seven parts including genetic background, pathology,  pathophysiology, and the latest prediction and treatment of preeclampsia. Specific basic topics such as immunological maladaptation, placental adenosine signaling, and new prediction markers are also expounded by experts. Thus it benefits not only obstetricians, pediatricians, nephrologists, diabetologists, and cardiologists, but also immunologists, endocrinologists, geneticists, pathologists, biologists, and molecular biologists who are interested in the treatment of hypertension in pregnancy.

 

 

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Pre-Menopause, Menopause and Beyond: Volume 5: Frontiers in Gynecological Endocrinology

Pre-Menopause, Menopause and Beyond: Volume 5: Frontiers in Gynecological Endocrinology

Pre-Menopause, Menopause and Beyond: Volume 5

This volume represents an up-to-date overview on pre-Menopause and Menopause, with their respective clinical implications and therapies. The aim is to clarify possible doubts and clinical approaches to this particular period in a woman’s life and how to face it, both offering solutions to actual problems and focusing on the potential impact of preventive medicine in improving women’s health and quality of life.

The volume is published within the International Society of Gynecological Endocrinology (ISGE) Series, and is based on the 2017 International School of Gynecological and Reproductive Endocrinology Winter Course.

This book, covering a very wide range of topics with particular focus on fertility in pre- and peri-menopausal women, climacteric and menopausal symptoms, impact of PCOS on post-menopausal health, breast disease, surgical treatments and therapies, will be an invaluable tool for gynecologists, endocrinologists, and experts in women’s health.

 

 

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Radiation Therapy Techniques for Gynecological Cancers: A Comprehensive Practical Guide

Radiation Therapy Techniques for Gynecological Cancers: A Comprehensive Practical Guide

This book is a practical guide to the use of modern radiation therapy techniques in women with gynecological cancers. Step-by-step instruction is provided on simulation, contouring, and treatment planning and delivery for cancers of the cervix, endometrium, vagina, and vulva. Beyond external beam radiation delivery, full details are presented on three-dimensional brachytherapy at all sites for which it is applicable. Moreover, in-depth guidance is offered on the various advanced techniques of radiation delivery, including intensity-modulated radiation therapy, image guidance for external beam and brachytherapy, and stereotactic body radiotherapy.

Radiation therapy is a critical component of the multidisciplinary management of gynecological tumors. With modern technology, both external beam radiation and brachytherapy can be delivered in a highly conformal way. This requires precise contouring and accurate planning techniques. In clearly describing the indications for and the delivery of quality radiation therapy for gynecological tumors, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and radiotherapy residents.

 

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Frontiers in Gynecological Endocrinology: Volume 1: From Symptoms to Therapies

Frontiers in Gynecological Endocrinology: Volume 1: From Symptoms to Therapies 

This volume represents an up-to-date overview on the major areas of gynecological endocrinology, providing the reader with a complete explanation of female endocrine regulation and metabolism and relevant disorders and treatment. It is published within the International Society of Gynecological Endocrinology (ISGE) Series and is based on the 2013 International School of Gynecological and Reproductive Endocrinology Summer Course. The book covers a very wide range of topics – from primary amenorrhea to menopause, from the impact of ovarian surgery on fertility to fertility cryopreservation, from metabolic syndrome and polycystic ovary to premature ovarian failure and from the clinical impact of selective progesterone receptor modulators to the use of progesterone in prevention of premature labor. It will be an important tool for obstetricians and gynecologists, endocrinologists and experts in women’s health as well as interested GPs.

 

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Frontiers in Gynecological Endocrinology: Volume 3: Ovarian Function and Reproduction

Frontiers in Gynecological Endocrinology: Volume 3: Ovarian Function and Reproduction

This volume represents an up-to-date overview on ovarian functions and reproduction, providing the reader with the latest advances in gynecological endocrinology. It is published within the International Society of Gynecological Endocrinology (ISGE) Series, and is based on the 2015 International School of Gynecological and Reproductive Endocrinology Winter Course. The book covers a very wide range of topics with particular focus on ovulation and assisted reproduction, ovarian aging and fertility, and premature ovarian failure.
The volume will be an invaluable tool for gynecologists, endocrinologists, obstetrician, and experts in women’s health.

 

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Frontiers in Gynecological Endocrinology: Volume 4

Frontiers in Gynecological Endocrinology: Volume 4

This volume provides a comprehensive, up-to-date overview on pediatric and adolescent gynecological endocrinology. It covers a very wide range of topics with a particular focus on disorders of sex differentiation, pubertal maturation, growth disorders, primary and secondary amenorrhea, menstrual disorders in adolescents and young adults, sexuality, contraception, and pregnancy. The authors are international well-known experts who document the latest clinical experience in this continuously evolving field and provide practical guidance on the evaluation and treatment of female pubertal problems.

The book is published within the International Society of Gynecological Endocrinology (ISGE) Series and is based on the 2015 International School of Gynecological and Reproductive Endocrinology (ISGRE) Summer Course. It will be an invaluable reference for gynecologists, endocrinologists, pediatricians, and experts in women’s health.

 

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Precision Medicine in Gynecology and Obstetrics

Precision Medicine in Gynecology and Obstetrics

This volume presents the scientific advances and current status of our understanding of precision medicine for common diseases in gynecology and obstetrics. Standard treatments based on clinical guidelines in the field have been established for decades, and those are essential to daily clinical practice. Meanwhile comprehensive genomic and genetic analyses have led to personalized medicine by precise clinical and genomic approaches. This book is organized into two major parts, gynecology and obstetrics, and the chapters in each part give a clear exposition of the current knowledge and the future perspectives for the treatment of various gynecological cancers, maternal disorders, and other diseases that affect female patients. Topics on novel treatment strategy with the application of molecular targeted drugs, immunotherapy, and prevention medicine are also covered.

This collection benefits not only experienced gynecologists and obstetricians, but also young physicians who would like to begin clinical and basic research on diseases in women, researchers in basic medicine, and all medical oncologists who are involved in gynecological cancers.

 

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Surgery for Gynecologic Cancer (Comprehensive Gynecology and Obstetrics)

Surgery for Gynecologic Cancer (Comprehensive Gynecology and Obstetrics)

This comprehensive volume provides exhaustive interpretations of surgery for gynecologic cancer. In these chapters, expert authors expound the history, principles and indications, preoperative evaluations, techniques, morbidity, and the future prospects for each surgical procedure. Also included are comparisons of the training systems of gynecologic surgeons in Japan and the USA.

Recently, minimally invasive surgeries such as laparoscopic and robotic approaches have been introduced into the gynecologic oncology field. Readers will be interested to know the history, advances, and current status of gynecologic surgery in Japan.

This collection methodically broadens understanding of new surgical methods with quality assurance aimed at saving the cancer patient’s life, from the point of view of gynecologic oncologists. Thus the book benefits not only experienced gynecologists, but also young physicians and all medical oncologists who are involved in gynecologic cancers.

 

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Frontiers in Ovarian Cancer Science (Comprehensive Gynecology and Obstetrics)

Frontiers in Ovarian Cancer Science (Comprehensive Gynecology and Obstetrics)

This volume presents the latest advances and the current status of our understanding regarding ovarian cancer, addressing both the basic and clinical aspects of the disease. In terms of basic medicine, the WHO Classification of Tumors of Female Reproductive Organs was revised in 2014, and that version addresses several new concepts and histopathological classifications not previously included. One of the most revolutionary breakthroughs concerns the genesis of epithelial ovarian tumors, shifting the focus from the ovarian surface epithelium to serous tubal intraepithelial carcinomas. Clinically, the mortality rate of epithelial ovarian cancer has gradually increased over the past few decades, making it essential to pursue multidisciplinary treatment and apply novel techniques such as neoadjuvant chemotherapy in daily clinical practice. The primary clinical task is the effective treatment of recurrent ovarian cancer with early palliative medicine. Fertility-sparing surgery may also be pursued depending on histologic subtypes, stage, extent of disease, and preexisting ovarian reserve with the concept of oncofertility.
On the basis of the considerations described above, each expert author elucidates the science of ovarian cancer in detail, thus providing a collection that will benefit young medical oncologists and seasoned gynecologists and obstetricians alike.

 

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Uterine Fibroids and Adenomyosis (Comprehensive Gynecology and Obstetrics)

Uterine Fibroids and Adenomyosis (Comprehensive Gynecology and Obstetrics)

This volume elucidates state-of-the-art findings of uterine fibroids and adenomyosis, incorporating expert basic knowledge.

Uterine fibroids and adenomyosis are common uterine tumors in reproductive-age women. However, the pathogenesis of the tumors is still poorly understood, and both genetic and environmental factors may be involved in their generation or development. Recent research on the genomics and molecular biology of uterine fibroids and adenomyosis has facilitated a better understanding of the pathogenesis and pathophysiology of these benign tumors.

Renowned experts provide detailed discussions of basic research and clinical aspects of uterine fibroids and adenomyosis in this book, from histopathology and molecular pathogenesis to diagnosis and the latest treatment of uterine fibroids, including pregnancy complications of adenomyosis. A great deal of information and a deep understanding of molecular and genetic biology have led to development of more innovative treatments of these tumors. Thus this book benefits not only oncologists, seasoned gynecologists, and obstetricians, but also molecular biologists and other basic researchers who are involved in the treatment of uterine fibroids.

 

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