Category: Neurology/Neurosurgery

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Translating laboratory discoveries into successful therapeutics can be difficult. Clinical Trials in Neurology aims to improve the efficiency of clinical trials and the development of interventions in order to enhance the development of new treatments for neurologic diseases. It introduces the reader to the key concepts underpinning trials in the neurosciences. This volume tackles the challenges of developing therapies for neurologic disorders from measurement of agents in the nervous system to the progression of clinical signs and symptoms through illustrating specific study designs and their applications to different therapeutic areas. Clinical Trials in Neurology covers key issues in Phase I, II and III clinical trials, as well as post-marketing safety surveillance. Topics addressed include regulatory and implementation issues, outcome measures and common problems in drug development. Written by a multidisciplinary team, this comprehensive guide is essential reading for neurologists, psychiatrists, neurosurgeons, neuroscientists, statisticians and clinical researchers in the pharmaceutical industry.

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The first atlas to present neurovascular information and images based on catheter 3D rotational angiographic studies. The spectacular 3D images are extensively labeled and juxtaposed with conventional 2D angiograms for orientation and comparison. Anatomical color drawings and concise descriptions of the major intracranial vascular territories further enhance understanding of the complex cerebral vasculature. This atlas is an indispensable reference for anyone seeking a fuller appreciation of intracranial and cervical anatomy and pathology, regardless of specialty.

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Neurodegenerative diseases are major contributors to disability and disease, with Alzheimer’s and Parkinson’s diseases the most prevalent. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts in the field internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. The dementias, prion diseases, Parkinson’s disease and atypical parkinsonisms, neurodegenerative ataxias, motor neuron diseases, degenerative diseases with chorea, iron and copper disorders, and mitochondrial diseases, are all methodically presented and discussed, with extensive illustrations. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.

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Endovascular intervention – using medication and devices introduced through catheters or microcatheters placed into the blood vessels through a percutaneous approach – has emerged as a relatively new minimally invasive approach to treat cerebrovascular disease and possibly intracranial neoplasms. This textbook provides a comprehensive review of principles pertinent to endovascular treatment of cerebrovascular diseases and intracranial tumors, with a detailed description of techniques for these procedures and periprocedural management strategies. Particular emphasis is placed on expert interpretation of the quality of evidence provided and implications for practice related to endovascular procedures. This will be essential reading for clinicians working in interventional neurology and cardiology, endovascular neurosurgery, vascular surgery and neuroradiology.

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The maze of neuroanatomy, symptomatology, and neurologic syndromes can be daunting to the primary care practitioner. Patients are often quickly referred to a specialist or subjected to a range of expensive diagnostic tests.

With this clear and practical reference, you will address the challenges of neurologic diagnosis and management at the primary care level—with straightforward illustrated guidance on neuroanatomy, physical examination, the neurologic workup, diagnostic tests, differential diagnosis, and treatment options.

Begin your journey from complexity to clarity.

• In-depth coverage addresses a range of commonly encountered neurologic disorders, showing you what to look for, what tests to order, and how the results affect your treatment choices.
• Abundant, colorful illustrations help you understand critical neuroanatomy and recognize clinically significant anomalies.
• Synopses of etiology, diagnosis, and treatment for each disease give you the information you need to understand and address the patient’s problem.
• Differential diagnosis of neurologic symptoms and signs are addressed, together with the work-up of each symptom and sign—all arranged in alphabetical order for easy reference.
• Case studies bring the diseases to life by highlighting salient features to help hone your physical examination and diagnostic skills.
• Useful appendices outline additional special examination techniques, laboratory workup for neurologic symptoms, and treatment guidelines for each disease.
• Thorough references guide you to resources that address rare disorders and controversial diagnostic procedures not covered in the text.
• Handy glossary provides a fingertip reference to commonly used terms.

Before you evaluate your next patient…be sure this indispensable reference is in your hands. Order your copy today!

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This classic, succinct, well-illustrated textbook simplifies neuroscience content to focus coverage on the essentials and helps students learn important neuroanatomical facts and definitions. Descriptions and illustrations of the regional anatomy of the central nervous system are followed by accounts of the functional pathways. The level of treatment is suited to increasingly shorter neuroanatomy courses for medical and allied health students.

The Ninth Edition features new and improved artwork, updates in current trends and terminology, and additions/updates to the Cranial Nerves chapter and Cells of the Nervous System chapter.

A companion Website offers online text, more than 450 interactive multiple-choice review questions, case studies, glossary, eponyms, abbreviations, an expanded version of selected chapters, and images from the book.

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Blueprints Neurology provides students with a complete review of the key topics and concepts—perfect for clerkship rotations and the USMLE. This edition has been completely updated—including new diagnostic and treatment information throughout—while maintaining its succinct, organized, and concise style. 100 board-format questions and answers with complete correct and incorrect answer explanations appear at the end of the book.

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