Target Volume Delineation and Treatment Planning for Particle Therapy: A Practical Guide (Practical Guides in Radiation Oncology) 1st ed. 2018 Edition

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This handbook is designed to enable radiation oncologists to treat patients appropriately and confidently by means of particle therapy. The orientation and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular.  Disease-specific chapters provide guidelines and concise knowledge on CTV selection and delineation and identify aspects that require the exercise of caution during treatment planning. The treatment planning techniques unique to proton therapy for each disease site are clearly described, covering beam orientation, matching/patching field techniques, robustness planning, robustness plan evaluation, etc. The published data on the use of particle therapy for a given disease site are also concisely reported. In addition to fully meeting the needs of radiation oncologists, this “know why” and “know how” guide to particle therapy will be valuable for medical physicists, dosimetrists,  and radiation therapists.

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The Structure of Healthy Life Determinants: Lessons from the Japanese Aging Cohort Studies (International Perspectives on Aging)

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About the Author

Medical Writing: A Guide for Clinicians, Educators, and Researchers 3rd ed. 2018 Edition

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This book is a clear and comprehensive guide that assists readers in translating observations, ideas, and research into articles, reports, or book chapters ready for publication. For both researchers and practicing physicians, skills in medical writing are essential. Dr. Robert B. Taylor, a distinguished leader in academic medicine, uses a clear, conversational style throughout this book to emphasize the professional and personal enrichment that writing can bring. The text includes in depth instructions for writing and publishing: review articles, case reports, editorials and letters to the editor, book reviews, book chapters, reference books, research protocols, grant proposals, and research reports. This third edition is additionally fully updated to include the intricacies of medical writing and publishing today, with new coverage of: open access, pay to publish and predatory journals, peer review fraud, publication bias, parachute studies, public domain images, and phantom authors. Loaded with practical information, tips to help achieve publication, and real world examples, Medical Writing can improve skills for clinicians, educators, and researchers, whether they are new to writing or seasoned authors.

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Experimental Investigations into Sarcomas: Therapy Using Ferromagnetically Induced Cytostatics 1st ed. 2018 Edition

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Manfred Georg Krukemeyer first describes magnetic drug targeting, by which is meant the focused application of drugs, e.g. the introduction of a cytostatic, and which is aimed at optimising its locally therapeutic effect. The author thus achieves a high concentration of cytostatic at the site of the tumour. The particles have to be large enough to be attracted by a magnetic field and so find their way into the tumour, where they release their active ingredient. The aim of the hypothesis formed by one of the author’s study groups was to show in a scientific experiment that in this case cytostatics coupled with iron particles [Fe3O4] can be introduced into a tumour. The focused introduction of drugs – magnetic drug targeting – results in faster arrival of the active ingredient at the target site together with a reduced quantity of active substances. For this reason magnetic drug targeting is also interesting from an economic point of view.

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The Epidemiology of Aging

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The average age of the world’s population is increasing at an unprecedented rate and this increase is changing the world. This “Silver tsunami” emphasizes the need to provide advanced training in epidemiology and increase the cadre of experts in the study of aging. This book is designed to summarize unique methodological issues relevant to the study of aging, biomarkers of aging and the biology/physiology of aging and in-depth discussions of the etiology and epidemiology of common geriatric syndromes and diseases. Contributing authors in the book represent many disciplines, not only epidemiology and clinical geriatrics, but also demography, health services, research, cardiovascular disease, diabetes, psychiatry, neurology, social services, musculoskeletal diseases and cancer. The aim of the book is to provide a broad multidisciplinary background for any student/researcher interested in aging. The material in the book is organized and comprehensive. It represents the most up-to-date information on the scientific issues in aging research written by academics who specialize in research and training in the broad field of aging. The structure and organization of the book reflects our course series in the Epidemiology of Aging starting with the broad issues of demography and methodology, and then addressing specific health conditions and geriatric conditions common to older persons.

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Stem Cell Aging: Mechanisms, Consequences, Rejuvenation 1st ed

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From the Back Cover

Recent Advances on the Modular Organization of the Cortex

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From the Back Cover

Advances in the Canine Cranial Cruciate Ligament (AVS Advances in Veterinary Surgery) 2nd Edition

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Advances in the Canine Cranial Cruciate Ligament, Second Edition presents in-depth, focused, and updated coverage of current knowledge on cruciate ligament rupture, using a multidisciplinary, evidence-based approach.

  • Presents a state-of-the-art summary of the most recent knowledge on this important cause of lameness in dogs
  • Led by a highly respected surgeon and researcher, with chapters written by leading experts in the field
  • Provides an update to the groundbreaking first edition, with six new chapters

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Advances in Personalized Nanotherapeutics 1st ed. 2017 Edition

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From the Back Cover

Health agencies have declared personalized nanomedicine as an important area to investigate novel therapies to combat against targeted diseases with no-side effects. The disease profile varies from patient-to-patient and standard therapies sometime are unsuitable for complete cure. This raises the demand of nanomedicine development. The tunable therapeutic salient features of nanomedicine including site-specific delivery and controlled release of a specific drug according to patient requirement make nanomedicine very special. Such of human compatible personalization is very useful in diseases management required to optimize a therapy for health care. Knowing the potentials of the nanomedicines, significant efforts are being to design and develop nano-enabled therapeutic strategies to cure and monitor diseases contributing to personalized health care. As per state-of-the-art, various approaches have been optimized resulting in development of pharmacologically relevant personalized nanomedicine to combat against diseases with improved efficacy and no adverse effects.

In this book, we described the fundamentals nanomedicine, nanotechnology for nanomedicine development, approach of personalized nanomedicine, potential novel nano-carriers for site-specific drug delivery, role of nano-bio-technology for efficient therapeutics, nano-pharmacology, targeted CNS drug delivery, stimuli- responsive drug release, aspects of bioinformatics for diseases management, miniaturized bio-sensing systems for diseases detection with monitoring, and nano-bio-technology for diseases management. The challenges in personalized nano-therapeutics development, possible vision to overcome challenges, and future prospects to promote therapies for clinical application are also discussed in this book. We believe that present book would serve as a platform for new scholars of academia and industries to understand state-of-the-art of nano-bio-technology for therapeutics to plan future research to develop effective personalized nanomedicine against targeted diseases.

Our book is a call for experts to explore multidisciplinary research towards developing novel personalized nanomedicines to combat against targeted diseases to personalized health care.

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Biomedical Engineering: Bridging Medicine and Technology (Cambridge Texts in Biomedical Engineering) 2nd Edition

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The second edition of this popular introductory undergraduate textbook uses examples, applications, and profiles of biomedical engineers to show students the relevance of the theory and how it can be used to solve real problems in human medicine. The essential molecular biology, cellular biology, and human physiology background is included for students to understand the context in which biomedical engineers work. Updates throughout highlight important advances made over recent years, including iPS cells, microRNA, nanomedicine, imaging technology, biosensors, and drug delivery systems, giving students a modern description of the various subfields of biomedical engineering. Over two hundred quantitative and qualitative exercises, many new to this edition, help consolidate learning, whilst a solutions manual, password-protected for instructors, is available online. Finally, students can enjoy an expanded set of leader profiles in biomedical engineering within the book, showcasing the broad range of career paths open to students who make biomedical engineering their calling.

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