The Immune System (Your Body: How It Works)
Examines the workings of a complex structure, the body’s defense against disease and infection.
Category: Immunology
AI for Immunology (AI for Everything) 1st Edition
1st Edition
The bioscience of immunology has given us a better understanding of human health and disease. Artificial intelligence (AI) has elevated that understanding and its applications in immunology to new levels. Together, AI for immunology is an advancing horizon in health care, disease diagnosis, and prevention. From the simple cold to the most advanced autoimmune disorders and now pandemics, AI for immunology is unlocking the causes and cures.
Key features:
- A highly accessible and wide-ranging short introduction to AI for immunology
- Includes a chapter on COVID-19 and pandemics
- Includes scientific and clinical considerations, as well as immune and autoimmune diseases
Type 2 Immunity: Methods and Protocols (Methods in Molecular Biology, 1799) 1st ed. 2018 Edition
This book provides researchers the opportunity to investigate type-2-associated diseases in their laboratories. Beginning with chapters describing various models of type-2 immunity, the volume then continues by detailing cellular protocols designed to identify, characterize, and assess the function of key adaptive and innate immune cells involved in type-2 inflammation; approaches to isolate and evaluate specific cellular subsets at the genetic, epigenetic, and molecular level; protocols to assess type-2 immunity and its relationship to organismal and metabolic systems (ex. Microbiome). This book concludes with a section that explores the use of primary human cells in evaluating relevance to the clinic. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshootingand avoiding known pitfalls.
Vital and authoritative, Type 2 Immunity: Methods and Protocols aims to provide a broad network of methods that can be used to develop a hypothesis and investigate its potential from bench to beside.
The Immune System: A Very Short Introduction (Very Short Introductions) Illustrated Edition
The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.
In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. The immune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called “innate” immune responses, which react very fast to infection, and “adaptive” immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading to serious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the “Immune system v2.o” – how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.
ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Review of Microbiology and Immunology
Review of Microbiology and Immunology
Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring 1st Edition
Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring.
The book is written for pathologists, toxicologists, and transplant surgeons who are involved in the management of transplant patients, offering them in-depth coverage of the management of immunosuppressant therapy in transplant patients with the goal of maximum benefit from drug therapy and minimal risk of drug toxicity.
This book also provides practical guidelines for managing immunosuppressant therapy, including the therapeutic ranges of various immunosuppressants, the pitfalls of methodologies used for determination of these immunosuppressants in whole blood or plasma, appropriate pharmacogenomics testing for organ transplant recipients, and when biomarker monitoring could be helpful.
- Focuses on the personalized management of immunosuppression therapy in individual transplant patients
- Presents information that applies to many areas, including gmass spectrometry, assay design, assay validation, clinical chemistry, and clinical pathology
- Provides practical guidelines for the initial selection and subsequent modifications of immunosuppression therapy in individual transplant patients
- Reviews the latest research in biomarker monitoring in personalizing immunosuppressant therapy, including potential new markers not currently used, but with great potential for future use
- Explains how monitoring graft-derived, circulating, cell free DNA has shown promise in the early detection of transplant injury in liquid biopsy
Nutrition, Immunity, and Infection 1st Edition
1st Edition
Both nutrition deficiency and overnutrition can have a significant effect on the risk of infection. Nutrition, Immunity, and Infection focuses on the influence of diet on the immune system and how altering one’s diet helps prevent and treat infections and chronic diseases. This book reviews basic immunology and discusses changes in immune function throughout the life course. It features comprehensive chapters on obesity and the role of immune cells in adipose tissue; undernutrition and malnutrition; infant immune maturation; pre- and probiotics; mechanisms of immune regulation by various vitamins and minerals; nutrition and the aging immune system; nutrition interactions with environmental stress; and immunity in the global health arena.
Nutrition, Immunity, and Infection describes the various roles of nutrients and other food constituents on immune function, host defense, and resistance to infection. It describes the impact of infection on nutritional status through a translational approach. Chapters bring together molecular, cellular, and experimental studies alongside human trials so that readers can assess both the evidence for the effects of the food component being discussed and the mechanisms underlying those effects. The impact of specific conditions including obesity, anorexia nervosa, and HIV infection is also considered.
Chapter authors are experts in nutrition, immunity, and infection from all around the globe, including Europe, Australia, Brazil, India, and the United States. This book is a valuable resource for nutrition scientists, food scientists, dietitians, health practitioners, and students interested in nutrition and immunity.
Roitt’s Essential Immunology (Essentials) 13th Edition
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Roitt’s Essential Immunology – the textbook of choice for students and instructors of immunology worldwide
Roitt’s Essential Immunology clearly explains the key principles needed by medical and health sciences students, from the basis of immunity to clinical applications. A brand new introduction sets the scene to section 1, Fundamentals of Immunology, introducing the microbial world and the strategies the body employs to defend itself. Each chapter then guides the reader through a different part of the immune system, and explains the role of each cell or molecule individually, and then as a whole. Section 2, Applied Immunology, discusses what happens when things go wrong, and the role the immune system plays alongside the damaging effects of a disease, including cancer, immunodeficiency, allergies and transplantation and the beneficial effects of vaccines.
The 13th edition continues to be a user-friendly and engaging introduction to the workings of the immune system, whilst supporting those who require a slightly more detailed understanding of the key developments in immunology. The content has been fully updated throughout and includes:
- An expansion on key clinical topics, including: innate immunity, autoimmune conditions, asthma, primary immunodeficiency, and HIV/AIDS
- Beautifully presented with improved artwork and new illustrations
- A range of learning features, including introduction re-cap boxes, end of chapter and section summaries to aid revision, as well as further reading suggestions, and a glossary to explain the most important immunology terms.
Roitt’s Essential Immunology is also supported by a companion website at www.roitt.com including:
- An additional online only chapter on immunological methods and applications
- Further interactive multiple choice and single best answer questions for each chapter
- Animations and videos showing key concepts
- Fully downloadable figures and illustrations, further reading and useful links
- Updated extracts from the Encyclopaedia of Life Sciences
- Podcasts to reinforce the key principles explained in the text
Philosophy of Immunology (Elements in the Philosophy of Biology)
Immunology is central to contemporary biology and medicine, but it also provides novel philosophical insights. Its most significant contribution to philosophy concerns the understanding of biological individuality: what a biological individual is, what makes it unique, how its boundaries are established and what ensures its identity through time. Immunology also offers answers to some of the most interesting philosophical questions. What is the definition of life? How are bodily systems delineated? How do the mind and the body interact? In this Element, Thomas Pradeu considers the ways in which immunology can shed light on these and other important philosophical issues. This title is also available as Open Access on Cambridge Core.
Allergy and Clinical Immunology (Mount Sinai Expert Guides) 1st Edition
1st Edition
Mount Sinai Expert Guides: Allergy and Clinical Immunology will provide trainees in allergy and immunology with an extremely clinical and accessible handbook covering the major disorders and symptoms, their diagnosis and clinical management.
Perfect as a point-of-care resource on the hospital wards and also as a refresher for board exam preparation, the focus throughout is on providing rapid reference, essential information on each disorder to allow for quick, easy browsing and assimilation of the must-know information. All chapters follow a consistent template including the following features:
- An opening bottom-line/key points section
- Classification, pathogenesis and prevention of disorder
- Evidence-based diagnosis, including relevant algorithms, laboratory and imaging tests, and potential pitfalls when diagnosing a patient
- Disease management including commonly used medications with dosages, management algorithms and how to prevent complications
- How to manage special populations, ie, in pregnancy, children and the elderly
- The very latest evidence-based results, major society guidelines and key external sources to consult
In addition, the book comes with a companion website housing extra features such as case studies with related questions for self-assessment, key patient advice and ICD codes. Each guide also has its own mobile app available for purchase, allowing you rapid access to the key features wherever you may be.
If you’re specialising in allergy and immunology and require concise, practical and clinical guidance from one of the world’s leading institutions in this field, then this is the perfect book for you.
This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.