Lung Innate Immunity and Inflammation: Methods and Protocols (Methods in Molecular Biology, 1809) 1st ed. 2018 Edition

This detailed book explores methods to isolate, characterize, and investigate key lung innate immune cells. Beginning with an overview, the volume then continues with methods for creating in vitro and in vivo model systems to study inflammatory lung diseases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Lung Innate Immunity and Inflammation: Methods and Protocols aims to be a guidebook and will be of value and interest to researchers investigating innate immunity and inflammation in the lung as well as other organs and tissues.

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Innate Antiviral Immunity: Methods and Protocols (Methods in Molecular Biology, 1656) 1st ed. 2017 Edition

This book explores methods to study the complex and evolving interplay between a virus and its host that range from model systems to the detection of chemical molecules. The collection starts with the application of humanized mice and zebrafish as model organisms to study virus-host interactions and induction of innate immune responses. Subsequent chapters outline diverse methods to detect small interfering RNAs, microRNAs, and virus-derived dsRNA from a variety of cells, tissues, and organisms, as well as to interrogating the cytosolic RNA and DNA sensing pathways, including using RNA PAMPs as molecular tools, purification of cGAMP from virus particles and infected cells, and mechanisms to visualize the subcellular localization and activation of the adaptor proteins MAVS and STING. Cutting-edge methods, including high-throughput and genome-wide CRISPR/Cas9 screens, chromosome conformation capture, and whole-exome sequencing, are described to identify novel mediators, pathways, and variants underlying host susceptibility. Given the importance of studying these pathways and players under physiologic conditions, methods describing the isolation of primary mouse sensory neurons and group 2 innate lymphoid cells are also provided. Finally, this collection comes full circle back to the whole organism level and concludes with epidemiological methods to investigate virus-host interactions and the induction of innate immunity. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and practical, Innate Antiviral Immunity: Methods and Protocols spans a diverse array of approaches to study and elucidate the intricacies of this vital area of study.
The chapter ‘Morphological Separation ofClustered Nuclei in Histological Images’ is published open access under a CC BY 4.0 license at link.springer.com. 

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Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support 1st Edition

Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health.

Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions.

This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here.

• Conceptualizes the key features in natural products which can boost immune function and immune health
• Explains the intricate mechanistic aspects and balance behind immune health
• Presents the pathophysiology of several diseases associated with immune system disruption

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Boosting Your Immunity For Dummies

Boost your body’s defenses to fight-off disease and live stronger and longer

Every single day our bodies are under attack from nasty little organisms which range from the pesky to the frighteningly serious. So, what’s the best way to fight back? Thankfully nature has provided us with a powerful interior armor-plating―and Boosting Your Immunity For Dummies shows you how to keep that crucial biological gift in tip-top condition.

Brought to you by bestselling author Kellyann Petrucci, MS, ND, a board-certified naturopathic physician, and Wendy Warner, a board certified holistic physician,―Boosting Your Immunity For Dummies sets out the sound ways we can supercharge our immune systems to prevent illnesses and diseases such as arthritis, autoimmune conditions, pneumonia, cancer, and the flu. Using a simple program of diet, exercise, stress-reduction, and nutritional supplements, we can keep our internal defenses humming happily along―and get generally healthier in the process!

• The best nutritional strategies to avoid cold and flu
• 40+ recipes that show healthy eating can also be delish
• Cutting-edge research on immune-boosting health and diet
• Lists and tips for keeping a low-cost, healthy pantry

Through diet, exercise, stress reduction, nutritional supplements, and the role of water, sunlight, and oxygen, you can harness the power of your immune system and drastically improve your immunity to disease.

P.S. If you think this book seems familiar, you’re probably right. The Dummies team updated the cover and design to give the book a fresh feel, but the content is the same as the previous release of Boosting Your Immunity For Dummies (9781118402009 find this on the copyright page). The book you see here shouldn’t be considered a new or updated product. But if you’re in the mood to learn something new, check out some of our other books. We’re always writing about new topics!

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Immunology: An Illustrated Outline 6th Edition

Immunology: An Illustrated Outline is both a guide to the essential principles of immunology and a concise dictionary of immunological terms. The book can be used to consolidate understanding in preparation for course exams and medical licensing exams, or as a refresher when immunology is encountered in related life sciences, such as microbiology, virology, and zoology.

The book is organized into five sections that represent the major topics in basic and clinical immunology. The Sixth Edition has been comprehensively revised to highlight the latest understanding of the field, particularly in the areas of innate immune defenses and antibody-based therapeutics.

• Concise explanations of immunological terms
• Full-color illustrations and micrographs to reinforce the text
• Each topic is set out in single- or double-page spreads
• Tables collate and summarize detailed information

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Clinical Immunology and Serology A Laboratory Perspective Fifth Edition

The perfect balance of theory and practice!
Here’s the practical introduction you need to understand the essential theoretical principles of clinical immunology and the serological and molecular techniques commonly used in the laboratory. You’ll begin with an introduction to the immune system; then explore basic immunologic procedures; examine immune disorders; and study the serological and molecular diagnosis of infectious disease.

An easy-to-read, student-friendly approach emphasizes the direct application of theory to clinical laboratory practice. Each chapter is a complete learning module with learning outcomes, chapter outlines, theoretical principles, illustrations, and definitions of relevant terminology. Review questions and case studies help you assess your mastery of the material. A glossary at the end of the book puts must-know information at your fingertips.

An access code inside new printed texts unlocks Lab Exercises and Branching Case Studies online at FADavis.com that offer more opportunities to apply theory to clinical laboratory practice.

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Cancer Chemotherapy, Immunotherapy and Biotherapy 6th Edition

Selected as a Doody’s Core Title for 2022!

Thoroughly revised and reformatted, the sixth edition of Cancer Chemotherapy, Immunotherapy and Biotherapy reflects recent significant changes in cancer treatment. This newly streamlined edition contains full-color illustrations, more tables for quick reference, and new immunotherapy and molecular targeted therapy content that brings you fully up to date with the state of the art in all current cancer therapies.

• Provides thorough, comprehensive coverage of the scientific and clinical aspects of immunotherapy, biotherapy, and chemotherapy.
• Includes significantly expanded information on immunotherapy and molecular targeted therapy, as well as the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance.
• Features a new, full-color format, a newly streamlined presentation. and more tables and figures throughout for quick access to high-yield information.
• Explains the rationale for use of drugs in specific schedules and combinations and offers guidelines for dose adjustment in specific situations.

Enhance Your eBook Reading Experience

• Read directly on your preferred device(s), such as computer, tablet, or smartphone.
• Easily convert to audiobook, powering your content with natural language text-to-speech.

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Immunological Implications and Molecular Diagnostics of Genitourinary Cancer

Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms.

• Discusses the impact of the immune system on the initiation, progression and treatment of cancer
• Provides insights on the important role of the suppressor genes and oncogenes in genitourinary cancers
• Shows the advantages of combining clinical issues of urologic cancers with immunological techniques, like immunohistochemistry and immunofluorescence
• Demonstrates the implications genitourinary cancer has on the human innate immune system

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