Category: Immunology

Handbook of Immunological Properties of Engineered Nanomaterials (Frontiers in Nanobiomedical Research) 1st Edition

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The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.

The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.

Readership: Researchers, academics, undergraduates and graduates in toxicology, immunotoxicology and nanomedicine, and industry (small and mid biotech companies and big pharmaceutical companies), as well as regulatory agencies (EPA, FDA) and physicians.

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Case Studies in Immunology: A Clinical Companion (Geha, Case Studies in Immunology: A Clinical Companion) 6th Edition

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Case Studies in Immunology, Sixth Edition, presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. The case histories illustrate essential points about the mechanisms of immunity and describe immunological problems seen in the clinic. This new edition vividly illustrates the importance of an understanding of immunology in diagnosis and therapy. Case Studies in Immunology highlights major common disorders of immunity, including hypersensitivity types I-IV, immune deficiencies, and autoimmune disorders. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the specific disorders. An end-of-case summary, questions, and discussion points conclude each case.

Case Studies in Immunology can be used as a stand-alone book, or as a clinical companion alongside Janeway’s Immunobiology, Eighth Edition. A marginal icon in Janeway’s Immunobiology provides the reader with a link to the relevant Case Study, where the science is applied in a clinical setting.

The book includes a total of 53 cases. The Sixth Edition is extensively revised and updated and includes ten new cases:

  • DiGeorge Syndrome
  • Hemophagocytic Lymphohistiocytosis
  • Chediak-Higashi Syndrome
  • Hyper IgE Syndrome
  • Ataxia Telangiectasia
  • Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome
  • Severe Congenital Neutropenia
  • Recurrent Herpes Simplex Encephalitis
  • Systemic Onset Juvenile Idiopathic Arthritis
  • Crohn’s Disease

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Crash Course Haematology and Immunology, 4e 4th Edition

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The new series of Crash Course continues to provide readers with complete coverage of the MBBS curriculum in an easy-to-read, user-friendly manner. Building on the success of previous editions, the new Crash Courses retain the popular and unique features that so characterised the earlier volumes. All Crash Courses have been fully updated throughout.

  • More than 90 illustrations present clinical, diagnostic and practical information in an easy-to-follow manner
  • Friendly and accessible approach to the subject makes learning especially easy
  • Written by students for students – authors who understand exam pressures
  • Contains ‘Hints and Tips’ boxes, and other useful aide-mémoires
  • Succinct coverage of the subject enables ‘sharp focus’ and efficient use of time during exam preparation
  • Contains a fully updated self-assessment section – ideal for honing exam skills and self-testing
  • Self-assessment section fully updated to reflect current exam requirements
  • Contains ‘common exam pitfalls’ as advised by faculty
  • Crash Courses also available electronically!
  • Online self-assessment bank also available – content edited by Dan Horton-Szar!

Now celebrating over 10 years of success – Crash Course has been specially devised to help you get through your exams with ease.

Completely revised throughout, the new edition of Crash Course is perfectly tailored to meet your needs by providing everything you need to know in one place. Clearly presented in a tried and trusted, easy-to-use, format, each book in the series gives complete coverage of the subject in a no-nonsense, user-friendly fashion.

Commencing with ‘Learning Objectives’, each chapter guides you succinctly through the topic, giving full coverage of the curriculum whilst avoiding unnecessary and often confusing detail. Each chapter is also supported by a full artwork programme, and features the ever popular ‘Hints and Tips’ boxes as well as other useful aide-mémoires. All volumes contain an up-to-date self-assessment section which allows you to test your knowledge and hone your exam skills.

Authored by students or junior doctors – working under close faculty supervision – each volume has been prepared by someone who has recently been in the exam situation and so relates closely to your needs. So whether you need to get out of a fix or aim for distinction Crash Course is for you!!

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Immunogenetics of Fungal Diseases 1st ed. 2017 Edition

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This book provides up-to-date information on immunogenetics of fungal diseases in the context of primary and acquired immunodeficiencies. Different aspects of this emerging field are covered, including epidemiology of fungal diseases, innate and adaptive antifungal immunity, and the role of immunogenetics in defining susceptibility to fungal diseases in primary (CMC, CGD, etc.) immunodeficiencies and hematologic patients. The available information will also be discussed in the scope of new biomarker discovery and development of immunotherapeutic approaches for personalized diagnostics and therapy. The book addresses Professors, researchers and advanced students of Medicine, Immunology, Microbiology and Genetics.

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Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins (Milestones in Drug Therapy) 1st ed. 2017 Edition

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This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities.

The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.

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Kuby Immunology 7th Edition

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The only textbook written for undergraduates by teachers of the course, this bestseller presents the most current concepts in an experimental context, conveying the excitement of scientific discovery, and highlighting important advances while providing unsurpassed pedagogical support for the first-time learner. The new edition is thoroughly updated, including most notably a new chapter on innate immunity, a capstone chapter on immune responses in time and space, and many new focus boxes drawing attention to exciting clinical, evolutionary, or experimental connections that help bring the material to life.

See what’s in the LaunchPad

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Neuro-Immuno-Gastroenterology 1st ed. 2016 Edition

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This book addresses important issues regarding the interaction between the nervous system, the immune system, and the digestive system. Gut flora has a profound influence on the shaping of the immune response, not only in the gastrointestinal system but also in the nervous system. Fascinatingly, manipulation of intestinal immune responses can be used to modulate neurological disease. Conversely, the nervous system and the psyche have significant effects on the functioning of the gut and liver.

After introductory chapters on the neurology, the immunology and microbiology of the gut, the effects of the gut immune system and gut flora and its manipulation on neurological disease are discussed, followed by molecular mimicry and immune tolerance in neuroimmune diseases. Additionally, several chapters deal with gastrointestinal manifestations of neurological diseases.

Neuro-Immuno-Gastroenterology is aimed at neurologists, gastroenterologists, and immunologists.

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Tumor Immunology: Methods and Protocols (Methods in Molecular Biology) 1st ed. 2016 Edition

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This volume explores the still undiscovered secrets of tumor immunology and cancer immunology by discussing the methods and techniques that world-renowned experts in the field use in their laboratories.  This book provides a better understanding of the rules governing tumor and cancer immunology, and discusses innovations in the technology of the immunological “smart bullets” (monoclonal antibodies, vaccines, tumor-reactive T cells) used to specifically target cancer cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Thorough and cutting-edge, Tumor Immunology: Methods and Protocols contains a wide breadth of subject coverage that any scientist, clinician, or industry professional interested in this field will find valuable.

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Immunology: An Illustrated Outline 5th Edition

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Immunology: An Illustrated Outline is both a review guide to the essential principles of immunology and a concise dictionary of immunological terms. It can be used as a review tool in preparation for course exams and medical licensing exams, or as a refresher when this content is encountered in related life science areas, such as microbiology and virology. The book also enables readers to look up specific terms in the index and locate the definitions, making it a powerful reference for interns, residents, and physicians in clinical practice.

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Immunology: Clinical Case Studies and Disease Pathophysiology 1st Edition

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  • 26 real-life cases illustrate the applications of basic immunology in clinical settings
  • May be utilized alone or as a companion to Immunology: A Short Course, 7th Edition by Richard Coico and Geofftry Sunshine (ISBN 9781118396919)
  • Each case study is introduced by clearly written descriptions of the major immunological disorders
  • Full colour photographs and illustrations complement complete presentation of real data
  • Includes complete set of problems and discussion questions for each chapter
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