Clinical Trials, Second Edition: Study Design, Endpoints and Biomarkers, Drug Safety, and FDA and ICH Guidelines 2nd Edition

0128042176

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Clinical Trials, Second Edition, offers those engaged in clinical trial design a valuable and practical guide. This book takes an integrated approach to incorporate biomedical science, laboratory data of human study, endpoint specification, legal and regulatory aspects and much more with the fundamentals of clinical trial design. It provides an overview of the design options along with the specific details of trial design and offers guidance on how to make appropriate choices. Full of numerous examples and now containing actual decisions from FDA reviewers to better inform trial design, the 2nd edition of Clinical Trials is a must-have resource for early and mid-career researchers and clinicians who design and conduct clinical trials.

  • Contains new and fully revised material on key topics such as biostatistics, biomarkers, orphan drugs, biosimilars, drug regulations in Europe, drug safety, regulatory approval and more
  • Extensively covers the “study schema” and related features of study design
  • Incorporates laboratory data from studies on human patients to provide a concrete tool for understanding the concepts in the design and conduct of clinical trials
  • Includes decisions made by FDA reviewers when granting approval of a drug as real world learning examples for readers

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Drug Utilization Research: Methods and Applications 1st Edition

1118949781

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Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understanding and evaluation of the processes of prescribing, dispensing and consumption of medicines and for the testing of interventions to enhance the quality of these processes. The discipline is closely related and linked mainly to the broader field of pharmacoepidemiology, but also to health outcomes research, pharmacovigilance and health economics.

Drug Utilization Research is a unique, practical guide to the assessment and evaluation of prescribing practices and to interventions to improve the use of medicines in populations. Edited by an international expert team from the International Society for Pharmacoepidemiology (ISPE), DUR is the only title to cover both the methodology and applications of drug utilization research and covers areas such as health policy, specific populations, therapeutics and adherence.

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http://upsto.re/sXwjubs

Middleton’s Allergy Essentials, 1e 1 Har/Psc Edition

0323375790

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For decades, health care practitioners have relied on Middleton’s Allergy as their go-to reference for comprehensive information on allergic disorders. Now Middleton’s Allergy Essentials, by Drs. Robyn E. O’Hehir, Stephen T. Holgate, and Aziz Sheikh, offers a concise resource that’s both easily accessible and highly authoritative. Perfect for clinicians in primary and secondary care settings, this practical volume covers what is most useful in your daily practice, with a strong emphasis on disease diagnosis and management.

    • A practical approach to evaluation, differential diagnosis, and treatment of allergic disorders, focused specifically on what the non-specialist needs to know for everyday practice.
    • Each chapter begins with a handy summary of key concepts to help you quickly identify important information.
    • Coverage of today’s hot topics includes asthma, drug allergies, food allergies and gastrointestinal disorders, anaphylaxis, atopic dermatitis, and allergic contact dermatitis.

 

  • Concise sections on mechanisms are included where relevant, keeping you up to date with this rapidly evolving field.
  • Authored by the same internationally recognized experts that produce Middleton’s Allergy, the definitive text in the field.
  • Ideal for physicians, residents, general and family practitioners, nurse practitioners, primary care doctors, hospitalists, general internists – anyone who is called upon to make effective diagnostic and treatment decisions regarding allergic disorders.

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http://upsto.re/siUdCwX

Henry’s Clinical Diagnosis and Management by Laboratory Methods, 23e 23rd Edition

0323295681

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Recognized as the definitive reference in laboratory medicine since 1908, Henry’s Clinical Diagnosis continues to offer state-of-the-art guidance on the scientific foundation and clinical application of today’s complete range of laboratory tests. Employing a multidisciplinary approach, it presents the newest information available in the field, including new developments in technologies and the automation platforms on which measurements are performed.

  • Provides guidance on error detection, correction, and prevention, as well as cost-effective test selection.
  • Features a full-color layout, illustrations and visual aids, and an organization based on organ system.

 

  • Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.
  • Features the latest knowledge on cutting-edge technologies of molecular diagnostics and proteomics.
  • Includes a wealth of information on the exciting subject of omics; these extraordinarily complex measurements reflect important changes in the body and have the potential to predict the onset of diseases such as diabetes mellitus.
  • Coverage of today’s hottest topics includes advances in transfusion medicine and organ transplantation; molecular diagnostics in microbiology and infectious diseases; point-of-care testing; pharmacogenomics; and the microbiome.
  • Toxicology and Therapeutic Drug Monitoring chapter discusses the necessity of testing for therapeutic drugs that are more frequently being abused by users.

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Dermatological Signs of Systemic Disease, 5e 5th Edition

0323358292

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The new edition of Dermatological Signs of Systemic Disease helps you identify a full range of common and rare systemic diseases early on so they can be managed as effectively as possible. Formerly titledDermatological Signs of Internal Disease, it takes an evidence-based approach to diagnosis and treatment, offering dependable clinical recommendations that enable you to attain definitive diagnoses of internal diseases that manifest on the skin.

  • Allows you to attain definitive diagnoses of internal diseases that manifest on the skin.
  • Uses a consistent, user-friendly format for easy reference.

 

  • Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.
  • Covers hot topics such as lupus erythematosus, dermatomyositis, autoinflammatory diseases, eosinophilic and neutrophilic dermatoses, and psoriasis therapies and co-morbidities.
  • Highlights newer therapies and treatment options for most diseases.
  • Includes over 500 full-color illustrations200 new to this edition – that provide the best possible representations of diseases as they appear in the clinic.
  • Features more viewpoints from an expanded team of nationally recognized experts in their respective fields.

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The 5-Minute Clinical Consult 2017 (The 5-Minute Consult Series) Twenty-Fifth Edition

1496339967

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Make quick and accurate diagnoses and treatment decisions at the point of care with this bestselling guide! The 5-Minute Clinical Consult Standard 2017 is a practical and useful resource for primary care clinicians, as well as those in family medicine, emergency medicine, nursing, and pediatrics. Using a three-column, bulleted format, the print edition provides rapid access to diagnosis, treatment, medications, follow-up, and associated factors for more than 570 diseases and conditions, plus over 110 diagnostic and therapeutic algorithms.

The 5-Minute Clinical Consult Standard 2017, 25th Edition, includes:

  • Succinct information on more than 570 commonly encountered diseases and disorders and 110 treatment and diagnostic algorithms (20 are new!)
  • ICD-10 codes
  • Evidence-based medicine content, fully updated and easily accessible for quick reference.
  • Accurate drug dosing information carefully reviewed by a PharmD

Written by esteemed internal medicine and family medicine practitioners and published by the leading publisher in medical content, The 5-Minute Clinical Consult Standard 2017, 25th Edition includes a Free Trial to 5MinuteConsult.com

5MinuteConsult.com is a quicker, more valuable, evidence-based, online workflow tool easily integrated at the point of care. 5MinuteConsult.com provides online-exclusive content, including:

  •  Differential diagnosis support from an expanded collection of algorithms
  • Current evidence-based designations highlighted in each topic
  • 570+ commonly encountered diseases in print, with an additional 1,400 online topics, including content fromThe 5-Minute Pediatric Consult and Rosen & Barkin’s 5-Minute Emergency Medicine Consult
  • Thousands of images to help support visual diagnosis of all conditions
  • Video library of procedures, treatment, and physical therapy
  • A-to-Z Drug Database from Facts & Comparisons®
  • Laboratory test interpretation from Wallach’s Interpretation of Diagnostic Tests
  • More than 3,000 patient handouts in English and Spanish
  • ICD-10 codes, DSM-5 criteria, and SNOMED codes
  • Quick-access link to the U.S. Preventive Services Task Force calculator
  • Point-of-care CME/CE:  .5 credits while you search the site to find the best treatment for your patients. This activity has been reviewed and is acceptable for up to 20 prescribed credits by the AAFP and the ANCC

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Users’ Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice, Third Edition (Uses Guides to Medical Literature) 3rd Edition

0071794158

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The streamlined companion to the classic Users’ Guides to the Medical Literature–fully updated and revised

This compact guide condenses the most clinically relevant content of the landmark Users’ Guides to the Medical Literature to help you incorporate evidence-based medicine into your practice.

You will learn the principles of evidence-based medicine, how your practice can benefit from the constant stream of new medical literature, and how to differentiate good medical evidence from that which is inadequate or misleading.

This edition includes numerous updates, several new chapters, and a greater emphasis on the role of patient preferences and preappraised resources.

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Clinical Infectious Disease 2nd Edition

110703891x

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A fully updated version of this popular, clinically oriented, user-friendly text on infectious disease, with even more helpful graphics, tables, algorithms and images. It is packed full of information on diagnosis, differential diagnosis and therapy. In addition to the traditional organization of organ-system and pathogen-related information, this text also includes clinically helpful sections on the susceptible host (with individual chapters, for example, on the diabetic, the elderly, the injection drug user and the neonate), infections related to travel, infections related to surgery and trauma, nosocomial infection and bioterrorism. Positioned between the available encyclopedic tomes and the smaller pocket guides, this is a convenient, comprehensive and highly practical reference for all those practising in infectious diseases as well as internal or general medicine.

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http://upsto.re/sf6EbV5

1000 Questions and Answers from Kumar & Clark’s Clinical Medicine, 2e 2nd Edition

9780702044366

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• What causes hypertension in children?
• Is it common for epileptic patients to have post-ictal vomiting? If so, how often does this occur?
• Why is the incidence of parkinsonism less common in smokers?
• What is the role of urine examination in diabetic control?

Where do you turn to when you have a difficult medical question that needs answering?

The ‘Ask the Author’ online feature from the best-selling textbook Kumar & Clark’s Clinical Medicine has collected a wealth of questions and comments directly from medical students and doctors about topics that are of particular interest or difficulty to them.

Kumar and Clark have brought together over 1000 of the questions they have been asked along with their answers. It will appeal to the many fans of Kumar & Clark, from first-year students to practising doctors, and will provide a useful and interesting sounding board to help ensure best practice.

This unique book will provide you with a quick and easy way to discover the answers to your own medical questions…!

  • The writing style is appealing and conversational, designed to entertain as well as instruct.
  • Carries the ‘Kumar & Clark’ stamp of authority.
  • All questions fully indexed for ease of reference.
  • Covers topics that are easily misunderstood in medicine – good preparation for medical students, senior house officers/interns and specialists in training/residents preparing for written or oral exams.

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http://upsto.re/syqwaRP

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