Category: Clinical Skills

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The revised, updated Fifth Edition of this pocket book is a handy reference to consult when making bedside interpretations of clinical data. Remarkably complete for its small size, the book lists nearly 200 symptoms, physical signs, laboratory test results, and radiologic findings and their differential diagnoses.

This edition has a new, more user-friendly two-color design, tabs indicating sections, and shortened lists of the most common diagnoses. An expanded section on HIV infection covers new manifestations, including immune reconstitution syndrome. The infectious disease chapter has been revised to reflect its increasing importance in clinical medicine, the emergence of multi-drug resistant bacteria, and the threat of bioterrorism.

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Hutchison’s Clinical Methods, first published over a century ago, is the classic textbook on clinical skills. It provides an outstanding source of learning and reference for undergraduate medical students and postgraduate doctors. It seeks to teach an integrated approach to clinical practice, so that new methods and investigations are grafted onto established patterns of clinical practice, rather than added on as something extra. The text is organised so that both system-related and problem-oriented chapters are included. Particular emphasis is placed on the importance of the doctor-patient relationship, the essential skills needed for clinical examination, and for planning the appropriate choice of investigations in diagnosis and management.

• Provides a comprehensive account of the traditional methods of patient history-taking and examination but updated with a full account of the role of modern investigative techniques.
• A book for students of all ages and all degrees of experience.
• The most comprehensive account of clinical methods on the market.

• This long established textbook of clinical method has been thoroughly revised, with fewer chapters, so as to concentrate on the basic principles of history and examination in all the various clinical settings which medical students need to master.
• A new chapter concentrates on the assessment of patients presenting as emergencies.
• A new editorial team on this 23^rd Edition maintains the highest standards of content and presentation.
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This book provides students, teachers, researchers and clinicians with a strong and established source of information on advanced optical technologies that show real promise of being translated to clinical use.

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Serous (peritoneal, pleural and pericardial) effusions are a frequently encountered clinical finding in everyday medical practice and one of the most common specimen types submitted for cytological evaluation. The correct diagnosis of effusions is critical for patient management, as well as for prognostication and yet many clinicians find diagnosis and treatment of cancer cells in effusions very challenging.

Featuring multiple microscopic illustrations of all diagnostic entities and ancillary techniques (immunhistochemistry and molecular methods), this book provides a comprehensive, authoritative guide to all aspects of serous effusions, including etiology, morphology and ancillary diagnostic methods, as well as data related to therapeutic approaches and prognostication. Section one covers diagnosis for benign and malignant effusions including the etiological reasons for the accumulation of effusions that provides the reader with the full spectrum of differential diagnoses at this anatomic site. Section Two discusses biology, therapy and prognosis highlighting clinical approaches that may be of value to patients and the movement towards personalized medicine and targeted therapy.

Written by experts in the field internationally, Serous Effusions will provide an indispensible guide to all aspects of current practice for cytopathologists, cytotechnicians, pathologists, clinicians and researchers in training and practice.

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From newborns switched in the nursery to medication mix-ups and hospital-acquired infections, we are all familiar with the horror stories about hospital safety, and unfortunately, the statistics say we aren’t exaggerating. The safety issue in U.S. hospitals has become so profound and embedded, that we cannot hope to fix it without a paradigm shift in our approach. After defining and demonstrating the true depth of this dangerous concern, Safer Hospital Care: Strategies for Continuous Innovation elaborates on the steps required to make that paradigm shift a reality.

A respected and sought out expert on hospital safety, author Dev Raheja draws on his 25 years of experience as a risk management and quality assurance consultant to provide hospital stakeholders with a systematic way to learn the science of safe care. Supported by case studies as well as input from such paradigm pioneers as Johns Hopkins and Seattle Children’s, he explains how to:

• Adapt evidence-based safety theories and tools taken from the aerospace, nuclear, and chemical industries
• Identify the combination of root causes that result in an adverse event
• Apply analytical tools that can effectively measure hospital efficiency
• Establish evidence between Lean strategies and patient satisfaction
• Make use of various types of innovation including accidental, incremental, strategic, and radical, and establish a culture conducive to innovation

This practical guide shows how to find solutions that are simple and comprehensive, and can produce a high ROI. To reform hospitals, we must recognize that they are highly dynamic systems that must be fixed systemically. Instead of thinking in terms of continuous improvement, we need to think in terms of continuous innovation. Safe hospital care is not just about doing things right; it is also about breaking old habits, finding new tools and doing the right things.

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Clinical Trials, Second Edition, offers those engaged in clinical trial design a valuable and practical guide. This book takes an integrated approach to incorporate biomedical science, laboratory data of human study, endpoint specification, legal and regulatory aspects and much more with the fundamentals of clinical trial design. It provides an overview of the design options along with the specific details of trial design and offers guidance on how to make appropriate choices. Full of numerous examples and now containing actual decisions from FDA reviewers to better inform trial design, the 2nd edition of Clinical Trials is a must-have resource for early and mid-career researchers and clinicians who design and conduct clinical trials.

• Contains new and fully revised material on key topics such as biostatistics, biomarkers, orphan drugs, biosimilars, drug regulations in Europe, drug safety, regulatory approval and more
• Extensively covers the “study schema” and related features of study design
• Incorporates laboratory data from studies on human patients to provide a concrete tool for understanding the concepts in the design and conduct of clinical trials
• Includes decisions made by FDA reviewers when granting approval of a drug as real world learning examples for readers

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