Category: Clinical Skills

Antisense Therapeutics (Methods in Molecular Medicine) 1st Edition

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Leading researchers offer an authoritative survey and analysis of the latest findings on the rapid development of antisense oligonucleotides therapeutic and their application in various in vivo model systems. The book’s high-profile contributors provide timely accounts of their state-of-the-art strategies, discussing such topics as the synthesis and purification of oligonucleotides, their selection for a particular gene target, different methods of administration, and the use of various cell lines and cell culture systems. They also examine questions of cellular uptake, in vitro biological activity, in vivo biological activity, the pharmacology and pharmacokinetics of oligonucleotides, and the application of oligonucleotides to the central nervous system.

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Herpes Simplex Virus Protocols (Methods in Molecular Medicine) 1998th Edition

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Herpes Simplex Virus Protocols comprises a wide range of experimental protocols that should be especially useful to new workers in herpes virology. Hopefully, it will also provide information for those with experience in the field, as well as those embarking on techniques that are new to them. Obviously the range of topics covered cannot be comprehensive, but we have tried to provide protocols dealing with those procedures that are most widely used; and we have selected expert authors accordingly. We have also tried to cover the range from the more biological in vivo maneuvers to purely molecular procedures, taking into account the topical interest in the potential use of HSV as a therapeutic tool. In this way there should be sufficient inf- mation for most procedures the average herpes virologist is likely to require– at least at this moment in time! Since the herpesviruses are a large family, we have largely based the protocols on the virus we know best–herpes simplex virus. With this as the prototype, it should be relatively easy to extrapolate and make the necessary modifications required for application to some of the other herpesviruses, especially members of the alpha group, such as PRV and EHV. It would have been an impossible task to include chapters covering the unique aspects of each known herpesvirus.

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Hypoxia: Translation in Progress (Advances in Experimental Medicine and Biology) 1st ed

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The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before ‘translational medicine’ was a catchphrase, the founders of the International Hypoxia Symposia brought together basic scientists, clinicians and physiologists to live, eat, ski, innovate and collaborate in the Canadian Rockies.

This collection of reviews and abstracts is divided into six sections, each covering new and important work relevant to a broad range of researchers interested in how humans adjust to hypoxia, whether on the top of Mt. Everest or in the pulmonary or cardiology clinic at low altitude. The sections include:

  • Epigenetic Variations in Hypoxia
    High Altitude Adaptation
  • Hypoxia and Sleep
  • Hypoxia and the Brain
  • Molecular Oxygen Sensing
  • Physiological Responses to Hypoxia

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Comprehensive Clinical Plasma Medicine: Cold Physical Plasma for Medical Application 1st ed. 2018 Edition

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This book presents the state of the art in clinical plasma medicine and outlines translational research strategies. Written by an international group of authors, it is divided into four parts. Part I is a detailed introduction and includes basic and recent research information on plasma sciences, plasma devices and mechanisms of biological plasma effects. Parts II and III provide valuable clinical insights f.e. into the treatment of superficial contaminations, ulcerations, wounds, treatment of cells in cancer, special indications like in heart surgery, dentistry, palliative treatment in head and neck cancer or the use of plasma in hygiene. Part IV offers information on how and where to qualify in plasma medicine and which companies produce and supply medical devices and is thus of particular interest to medical practitioners.

This comprehensive book offers a sciences based practical to the clinical use of plasma and includes an extended selection of scientific medical data and translational literature.

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Netter’s Clinical Anatomy, 4e (Netter Basic Science) 4th Edition

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Focus on the clinically relevant aspects of anatomy and bridge normal anatomy to common clinical conditions with Netter’s Clinical Anatomy, 4th Edition. This easy-to-read, visually stunning text features nearly 600 superb Netter-style illustrations that provide essential descriptions of anatomy, embryology, and pathology to help you understand their clinical relevance. Authored by John Hansen, PhD, an Honored Member of the American Association of Clinical Anatomists, this book is an ideal anatomy reference for students who want to make the most of their study time or need a concise review of clinical anatomy.

    • Clinical Focus boxes present hundreds of illustrated clinical correlations that bridge anatomy to pathophysiology. Every clinical correlation – more than 200 in all – is illustrated.
    • Features and Characteristics boxes explain the relation between structure and function.

 

    • Muscle/Ligament/Joint tables summarize attachment points, actions, and other key information related to each structure.
    • Both USMLE-style review questions and short answer questions online help you gauge your mastery of the material and identify areas where you may need further study.
  • Portable book size makes it easy to carry on the go.
    • More review questions, including figure- and image-based questions

 

  • More Clinical Focus boxes

 

  • eBook version included with purchase. This enhanced eBook experience includes additional multiple-choice questions, 3D models, and fully searchable text and images.

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Physical Activity Across the Lifespan: Prevention and Treatment for Health and Well-Being (Issues in Children’s and Families’ Lives)

The statistics are disturbing: steadily rising numbers of sedentary overweight children and obese teens, and a generation looking at a shorter life expectancy than their parents’. But while it may be obvious that physical fitness benefits both the mind and body, a growing research base is supplying evidence of why this is so, and how these benefits may be reproduced in greater numbers.

Physical Activity Across the Lifespan makes a clear, scientific case for exercise, sports, and an active lifestyle in preventing illness and establishing lifetime health habits at both the individual and the population levels. The book focuses on key aspects of physical/mental well-being―weight, mood, and self-regulation―and the role of physical activity in public health and school-based interventions targeting these areas. Contributors review definitional and measurement issues salient to understanding what physical activity is, to analyzing benefits of participation, and to implementing effective interventions. Also addressed are limitations of current research, steps needed to continue building the field, and emerging therapeutic possibilities for activity, such as the role of rough and tumble play in preventing ADHD.

Included in the coverage:

Physical activity, cognition, and school performance.

The influence of social and built environments on physical activity in middle-aged and older adults.

Preventing and treating obesity through physical activity.

Physical activity in preventing drug use and treating chemical dependence.

Antidepressant properties of physical activity.

Schools as a foundation for physical activity and an active lifestyle.

Physical activity as an adjunct or booster to existing interventions.

Physical Activity Across the Lifespan is an innovative text for researchers and practitioners in various disciplines including health promotion/disease prevention, child and school psychology, education, health psychology, and public health, as well as program developers and policymakers in these areas.[amazon_link asins=’1461436052′ template=’ProductAd’ store=’aishabano-20′ marketplace=’US’ link_id=’9e961d97-5551-11e8-a4c5-9528d8ce6e35′]

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Multiple Choice Questions in Pain Management 1st ed. 2018 Edition

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This book presents current clinical knowledge relating to key topics in acute and chronic pain in a multiple choice question (MCQ) format. Individual chapters are devoted to subjects such as the anatomy of pain pathways, pain processing, evaluation of pain, different pain syndromes and pain involving different regions of the body, pharmacologic and physical pain management, neural blockade, and special procedures. Each of the MCQs has four or five answer options in true/false format, and the answers are discussed in detail with provision of suitable references whenever appropriate. Multiple Choice Questions in Pain Management will be especially valuable for those who are sitting anesthesia board exams anywhere in the world. It will, for example, meet the needs of candidates for the FRCA examination (in which 20–25% of MCQs relate to pain management) or the FFPMRCA examination (Fellowship of the Faculty of Pain Medicine of the Royal College of Anaesthetists). In addition, the book will be useful for pain fellows and for all clinicians who are seeking to improve their knowledge of pain management.

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Feeling Pain and Being in Pain (MIT Press) second edition Edition

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An examination of the two most radical dissociation syndromes of the human pain experience―pain without painfulness and painfulness without pain―and what they reveal about the complex nature of pain and its sensory, cognitive, and behavioral components.

In Feeling Pain and Being in Pain, Nikola Grahek examines two of the most radical dissociation syndromes to be found in human pain experience: pain without painfulness and painfulness without pain. Grahek shows that these two syndromes―the complete dissociation of the sensory dimension of pain from its affective, cognitive, and behavioral components, and its opposite, the dissociation of pain’s affective components from its sensory-discriminative components (inconceivable to most of us but documented by ample clinical evidence)―have much to teach us about the true nature and structure of human pain experience.

Grahek explains the crucial distinction between feeling pain and being in pain, defending it on both conceptual and empirical grounds. He argues that the two dissociative syndromes reveal the complexity of the human pain experience: its major components, the role they play in overall pain experience, the way they work together, and the basic neural structures and mechanisms that subserve them.

Feeling Pain and Being in Pain does not offer another philosophical theory of pain that conclusively supports or definitively refutes either subjectivist or objectivist assumptions in the philosophy of mind. Instead, Grahek calls for a less doctrinaire and more balanced approach to the study of mind–brain phenomena.

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Metal Allergy: From Dermatitis to Implant and Device Failure 1st ed. 2018 Edition

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This volume has been compiled in response to the ongoing revolution in our understanding of metal contact allergy, and the ensuing challenge this has created for clinicians and others to synthesize large amounts of sometimes contradictory data. It opens by providing a comprehensive overview of the use and regulation of metals in our society, metal properties, and available testing methodologies. Common and uncommon metal allergens and sources of exposure are then reviewed in depth, and detailed sections are devoted to hypersensitivity to metal implants (which may be associated with device failure and/or dermatitis), metal allergy in select patient populations, and less frequently encountered manifestations of metal allergy.

The prevalence of metal allergy in the general population is high: up to 17% of people are allergic to nickel, and 1–3% to cobalt and chromium. Environmental sources of metal exposure include jewelry, clothing, electronic devices, coins, leather, diet, and occupational exposure. As metals are ubiquitous, this book will be an indispensable reference text for a wide range of clinicians and investigators, meeting the needs of all who are interested in metal allergy and its diagnosis and management.

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