Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring 1st Edition

 

Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring 1st Edition

Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring.

The book is written for pathologists, toxicologists, and transplant surgeons who are involved in the management of transplant patients, offering them in-depth coverage of the management of immunosuppressant therapy in transplant patients with the goal of maximum benefit from drug therapy and minimal risk of drug toxicity.

This book also provides practical guidelines for managing immunosuppressant therapy, including the therapeutic ranges of various immunosuppressants, the pitfalls of methodologies used for determination of these immunosuppressants in whole blood or plasma, appropriate pharmacogenomics testing for organ transplant recipients, and when biomarker monitoring could be helpful.

  • Focuses on the personalized management of immunosuppression therapy in individual transplant patients
  • Presents information that applies to many areas, including gmass spectrometry, assay design, assay validation, clinical chemistry, and clinical pathology
  • Provides practical guidelines for the initial selection and subsequent modifications of immunosuppression therapy in individual transplant patients
  • Reviews the latest research in biomarker monitoring in personalizing immunosuppressant therapy, including potential new markers not currently used, but with great potential for future use
  • Explains how monitoring graft-derived, circulating, cell free DNA has shown promise in the early detection of transplant injury in liquid biopsy

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Immunotoxicology and Immunopharmacology (Target Organ Toxicology Series, 23) 3rd Edition

Immunotoxicology and Immunopharmacology (Target Organ Toxicology Series, 23) 3rd Edition

Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health. For the first time in the book’s history, an entire section covers the phylogeny and ontogeny of the immune system, spanning levels of biological complexity from earthworms to marine mammals.

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Immunopharmacology (Advances in Pharmacology, Volume 66) 1st Edition

Immunopharmacology (Advances in Pharmacology, Volume 66) 1st Edition

This new volume of Advances in Pharmacology explores the current state of Alzheimer’s disease research and therapeutics. Chapters cover such topics as the B cell targeted therapiesLymphotoxin family receptors in inflammation, and allergic inflammation and thymic stromal lymphopoietin. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

  • Explores the current state of Alzheimer’s disease research and therapeutics
  • Chapters cover a variety of topics such as the B cell targeted therapies, lymphotoxin family receptors in inflammation, and allergic inflammation and thymic stromal lymphopoietin
  • With the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike

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Comprehensive Pharmacology 1st Edition

Comprehensive Pharmacology 1st Edition

Comprehensive Pharmacology, Seven Volume Set is organized into twelve sections that explore therapeutic areas, with a total of 320 comprehensive articles and 6,800 pages of important findings. Sections contain highly detailed coverage of information that has been overseen by an editorial board made up of well-respected, field leading experts. The content in this book offers readers an in-depth and easily accessible reference work on every aspect of pharmacological research surrounding the pharmacology of all therapeutic applications of drugs, their mechanism of action and their therapeutic values.

These elements are essential as drugs are almost never tested and developed in the actual therapeutic system, but rather in test systems from which parameters must be determined to predict activity in systems of varying ambient physiology. As different technologies rapidly evolve, there is an ever-increasing level of knowledge about the pharmacology of known drugs, along with increasing capability to utilize pharmacological systems to predict new drug activity, all of which must be communicated to professionals in varying fields.

  • Contains chapters that follow a consistent and templated approach, resulting in well-structured content that enhances user experience and appeal
  • Offers a comprehensive review on a wealth of information on pharmacology and how it utilizes concepts and techniques from a broad array of sciences, ranging from chemistry to physiology to medicine
  • Includes a wider use of color and multimedia content, with interactive features, links, computational modeling and animations to illustrate the effects of toxic substances in various contexts

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Pharmacogenomics in Drug Discovery and Development (Methods in Molecular Biology, 2547) 3rd ed. 2022 Edition

Pharmacogenomics in Drug Discovery and Development (Methods in Molecular Biology, 2547) 3rd ed. 2022 Edition

This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful Methods in Molecular Biology series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care.
Authoritative and up-to-date, 
Pharmacogenomics in Drug Discovery and Development, Third Edition aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.

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A Handbook On Plant Health Medicines

A Handbook On Plant Health Medicines

Though different titles of plant protection books are available, no book is as much illustrative as the present book of Plant Health Medicines. The book ”A Handbook on Plant Health Medicines” is prepared with an objective to make available the scientific as well as working knowledge of useful and recommended plant protection and plant health medicines to the personnel associated with agriculture in different capacities and at different levels, and to the end users, i.e. farmers.

The book contains three sections viz. chemical molecules for control of plant diseases, chemical molecules to control plant physiological process and physiological disorders, and Pesticides for management of plant insect pests. These three sections are divided into 30 chapters. The respective section has got images of all the representative diseases, pests, as well as mineral deficiencies symptoms for the identification of the cause and different molecules for their control and rectification, thus making the book more practical use oriented to all personnel associated with agriculture sector. With its availability particularly, to pesticide shop dealers and farmers, the proper plant protection and plant health medicines will be applied in the agricultural ecosystem to manage the problem associated with plant health.

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Oxford Textbook of Medicine, Volume 1 – 4 6th Edition

Oxford Textbook of Medicine, Volume 1 – 4 6th Edition

The Oxford Textbook of Medicine is the foremost international textbook of medicine. Unrivalled in its coverage of the scientific aspects and clinical practice of internal medicine and its subspecialties, it is a fixture in the offices and wards of physicians around the world , as well as being a key resource for medico legal practitioners. Accessible digitally with regular updates, as well as in print, readers are provided with multiple avenues of access depending on their need and preference.

More comprehensive, more authoritative, and more international than any other textbook; 
Oxford Textbook of Medicine focuses on offering both perspective and practical guidance on clinical management and prevention of disease.

Introductory sections focus on the patient experience, medical ethics and clinical decision making, outlining a philosophy which has always characterized the 
Oxford Textbook of Medicine. It is humane, thought provoking, and aims to instill in readers an understanding of the role of medicine in society and the contribution it can make to the health of populations, and it does not shy away from discussion of controversial aspects of modern medicine.

As always, there is detailed coverage of all areas of internal medicine by the world’s very best authors. The 
Oxford Textbook of Medicine seeks to embody advances in understanding and practice that have arisen through scientific research. The integration of basic science and clinical practice is unparalleled, and throughout the book the implications of research for medical practice are explained. The core clinical medicine sections offer in depth coverage of the traditional specialty areas. The Oxford Textbook of Medicine has unsurpassed detail on infectious diseases: the most comprehensive coverage to be found in any textbook of medicine. Other sections of note include stem cells and regenerative medicine; inequalities in health; medical aspects of pollution and climate change; travel and expedition medicine; bioterrorism and forensic medicine; pain; medical disorders in pregnancy; nutrition; and psychiatry and drug related problems in general medical practice. The section on acute medicine is designed to give rapid access to information when it is needed quickly.

In response to ongoing user feedback there have been substantial changes to ensure that the 
Oxford Textbook of Medicine continues to meet the needs of its readers. Chapter essentials give accessible overviews of the content and a new design ensures that the textbook is easy to read and navigate. The evidence base and references continue to be at the forefront of research.

New to this edition is that purchasers of the print version of the 
Oxford Textbook of Medicine sixth edition will have free access on Oxford Medicine Online to all the content plus regular updates for the life of the edition.

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Practical Transfusion Medicine 6th Edition

Practical Transfusion Medicine 6th Edition

Practical Transfusion Medicine

Practical Transfusion Medicine, Sixth Edition

The pace of change in transfusion medicine is relentless, with new scientific and technological developments and continuing efforts to improve transfusion practice. This sixth edition of Practical Transfusion Medicine has been updated significantly to reflect the rapid changes in transfusion medicine since the fifth edition was published in 2017.

The primary purpose of this edition remains the same as the first: to provide a comprehensive guide to transfusion medicine. This book contains more depth of information than standard handbooks on transfusion medicine, whilst being more concise and approachable than a standard reference text.

This book covers the principles of transfusion medicine, the complications of transfusion, practice in blood centres and hospitals and clinical transfusion practice. This sixth edition includes a new section on patient blood management, cellular and tissue therapy, organ transplantation and the development of the evidence base for transfusion. It also features a new chapter on transfusion-associated circulatory overload to underline its importance as a complication of transfusion, and a reconfiguration of the section on clinical transfusion practice to allow consideration of the transfusion management of medical, surgical and haematology patients with and without bleeding.

This sixth edition of Practical Transfusion Medicine provides accessible and comprehensive coverage of the field of transfusion medicine. It is a standalone text that will be useful to clinical and scientific staff: not only for trainees who require an overview of the field, but also for established practitioners who are involved in some aspect of transfusion medicine and require a comprehensive, accessible reference book.

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Mollison’s Blood Transfusion in Clinical Medicine 12th Edition

Mollison’s Blood Transfusion in Clinical Medicine 12th Edition

Mollison’s Blood Transfusion in Clinical Medicine is an icon in the field of transfusion and the first edition was published in 1951. The book arose from the concept of the transfusionist, as both scientist and expert consultant. For many years, this text has provided the primary, and often the sole, reference for detailed information and practical experience in blood transfusion. The book is completely revised and updated throughout to include the latest advances and developments in the field.

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