Biomaterials and Immune Response: Complications, Mechanisms and Immunomodulation (Devices, Circuits, and Systems) 1st Edition

The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted materials as a failure of immune system/biomaterial interactions; iv) tissue-specific effects of immune response and its consequences for tissue engineering and regenerative medicine; v) immune reaction in a clinical context (periodontology). In the field of biomaterials there are significant advances in using immunomodulation techniques to improve the success rates of implantable materials. For better understanding of such techniques it is required to have a full grasp of the biomaterial–immune system interactions. This would greatly enhance the understanding of why the human body reacts to implants in a certain way and how to improve the clinical outcomes by developing immune-instructive biomaterials.

• Provides keen insight into biomaterial–immune cell interactions

• Presents an explanation of state-of-the-art methodologies in immunomodulation

• Offers a concise and simple-to-understand treatment of biomaterial–immune cell interactions for materials scientists in a biology heavy topic

• Explores a comprehensive overview of biomaterial related complications

• Provides extensive references at the end of each chapter to enhance study for this very hot research area

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Basic Immunology: Functions and Disorders of the Immune System 6th Edition

Meticulously reviewed and updated for today’s medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases―all designed to help students master this complex topic in the most efficient, effective manner possible.

• Emphasizes clinical aspects of immunology, including disease pathogenesis, the development of novel therapies based on basic science, and an appendix of clinical cases for real-world application.
• Provides top-notch instruction from experienced teachers, course directors, and lecturers led by well-known editor and author Dr. Abul Abbas.
• Features a highly readable writing style and practical organization, now with fully revised content and updated images to reflect recent important advances in today’s understanding of the immune system.
• Provides additional online features such as answers to in-book chapter review questions, helpful animations, and up to 10 self-assessment questions per chapter.
• Presents information in a format and style that maximizes usefulness to students and teachers studying medicine, allied health fields, and biology.
• Contains numerous features designed to help students understand key immunologic concepts: high-quality illustrations, practical tables, chapter outlines, bolded key points, and focus questions in every chapter for self-assessment and review.
• Includes an Enhanced eBook version with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

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How the Immune System Works (The How it Works Series) 6th Edition

How the Immune System Works has helped thousands of students understand what’s in their hefty immunology textbooks. In this book, Dr. Sompayrac cuts through the jargon and details to reveal, in simple language, the essence of this complex subject: how the immune system fits together, how it protects us from disease and, perhaps most importantly, why it works the way it does.

Featuring Dr. Sompayrac’s hallmark lively prose and engaging analogies, How the Immune System Works has been rigorously updated for this sixth edition, including the latest information on subjects such as vaccines, immunological memory, and cancer. A highlight of this edition is a new chapter on immunotherapies – currently one of the hottest topics in immunology.

Whether you are completely new to immunology, or require a refresher, How the Immune System Works will provide you with a clear and engaging overview of this fascinating subject.

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Transplantation Immunology: Methods and Protocols (Methods in Molecular Biology, 333) 2006th Edition

Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today’s optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.

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The Immune System: A Very Short Introduction (Very Short Introductions) Illustrated Edition

The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.

In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. The immune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called “innate” immune responses, which react very fast to infection, and “adaptive” immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading to serious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the “Immune system v2.o” – how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.

ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

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Cancer Chemotherapy, Immunotherapy and Biotherapy 6th Edition

Selected as a Doody’s Core Title for 2022!

Thoroughly revised and reformatted, the sixth edition of Cancer Chemotherapy, Immunotherapy and Biotherapy reflects recent significant changes in cancer treatment. This newly streamlined edition contains full-color illustrations, more tables for quick reference, and new immunotherapy and molecular targeted therapy content that brings you fully up to date with the state of the art in all current cancer therapies.

• Provides thorough, comprehensive coverage of the scientific and clinical aspects of immunotherapy, biotherapy, and chemotherapy.
• Includes significantly expanded information on immunotherapy and molecular targeted therapy, as well as the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance.
• Features a new, full-color format, a newly streamlined presentation. and more tables and figures throughout for quick access to high-yield information.
• Explains the rationale for use of drugs in specific schedules and combinations and offers guidelines for dose adjustment in specific situations.

Enhance Your eBook Reading Experience

• Read directly on your preferred device(s), such as computer, tablet, or smartphone.
• Easily convert to audiobook, powering your content with natural language text-to-speech.

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Immunological Implications and Molecular Diagnostics of Genitourinary Cancer

Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms.

• Discusses the impact of the immune system on the initiation, progression and treatment of cancer
• Provides insights on the important role of the suppressor genes and oncogenes in genitourinary cancers
• Shows the advantages of combining clinical issues of urologic cancers with immunological techniques, like immunohistochemistry and immunofluorescence
• Demonstrates the implications genitourinary cancer has on the human innate immune system

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Oxford Handbook of Clinical Immunology and Allergy (Oxford Medical Handbooks) 4th Edition

This new edition of Clinical Immunology and Allergy is a practical and clinically based guide for clinicians and laboratory staff to aid diagnosis and management of immunological and allergic disease, and provides examples of the correct selection and interpretation of immunological tests for a wide range of conditions. Fully updated from the previous edition, with the addition of new diseases recently identified from the use of genetic testing, and novel biological therapies and autoantibody tests, this title covers the entire breadth of the field, with the information at your fingertips.

Split into two sections, the first covering individual diseases and allergies, with diagnosis and management strategies, and the second describing appropriate laboratory tests and their interpretation, the Oxford Handbook of Clinical Immunology and Allergy is an invaluable reference text, and works as a succinct revision guide for the FRCPath in Immunology. Filled with cross-references to create a cohesive overview of a complex subject, and presented in concise bullet-points for detailed direction to the key facts, this handbook provides everything you need to help you in clinical practice.

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