Stiehm’s Immune Deficiencies: Inborn Errors of Immunity 2nd Edition

Stiehm’s Immune Deficiencies: Inborn Errors of Immunity 2nd Edition

Stiehm’s Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy.

  • Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians
  • Fills an increasingly deep gap in the information available to clinicians
  • Presents both clinical management and scientific advances for immune deficiencies
  • Provides a primary resource for physicians in the field of immunodeficiencies
  • Includes website access to a range of videos relevant to the topics discussed

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Vertigo and Disequilibrium: A Practical Guide to Diagnosis and Management 2nd Edition

Vertigo and Disequilibrium: A Practical Guide to Diagnosis and Management 2nd Edition

This authoritative guide provides a solid clinical foundation to help practitioners manage vertigo and balance disorders in practice

This updated edition provides a comprehensive basis for understanding, identifying, and treating the underlying multifactorial etiologies of dizziness and imbalance. Vertigo is a common malady for which patients seek treatment, yet the vestibular system and its associated disorders are often misunderstood. This book effectively demystifies this topic, with clinical pearls and knowledge from foremost experts in the field.

The first six chapters cover procuring a thorough patient history, examination techniques, computerized testing, radiological studies, surgical anatomy and physiology of the vestibular system, and laboratory testing. Subsequent chapters concisely detail the diagnosis and treatment of pathologies such as Meniere’s disease, benign paroxysmal positional vertigo, labyrithinitis, superior semicircular canal dehiscence syndrome, and unilateral peripheral vestibulopathy.

Key Features

Covers the full age continuum – from congenital and pediatric vestibular disorders – to balance conditions associated with aging
Highlights the most common pathologies such as BPPV, as well as fairly rare diseases like Mal de Debarquement syndrome and perilymph fistulas
Discusses the impact of alcohol, migraines, and allergies on the vestibular system and the intrinsic roles they play in causing dizziness
New insights on medications, rehabilitation, and the use of implantable vestibular devices
Expanded video library provides guidance on testing modalities, visual disturbances, nystagmus patterns, and specific disorders
Physicians who read this authoritative guide will gain knowledge that is essential for optimal management of patients with vertigo and disequilibrium. It is an invaluable resource for otolaryngologists, as well as neurologists, physical therapists, internists, geriatricians, family practitioners, audiologists, and even cardiologists.

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Neurological Disorders and Imaging Physics: Applications in dyslexia, epilepsy and Parkinson’s (Volume 5)

Neurological Disorders and Imaging Physics: Applications in dyslexia, epilepsy and Parkinson’s (Volume 5)

Imaging Anatomy Brain and Spine 1st Edition

Imaging Anatomy Brain and Spine 1st Edition

This richly illustrated and superbly organized text/atlas is an excellent point-of-care resource for practitioners at all levels of experience and training. Written by global leaders in the field, Imaging Anatomy: Brain and Spine provides a thorough understanding of the detailed normal anatomy that underlies contemporary imaging. This must-have reference employs a templated, highly formatted design; concise, bulleted text; and state-of- the-art images throughout that identify the clinical entities in each anatomic area.

Features more than 2,500 high-resolution images throughout, including 7T MR, fMRI, diffusion tensor MRI, and multidetector row CT images in many planes, combined with over 300 correlative full-color anatomic drawings that show human anatomy in the projections that radiologists use.
Covers only the brain and spine, presenting multiplanar normal imaging anatomy in all pertinent modalities for an unsurpassed, comprehensive point-of-care clinical reference.
Incorporates recent, stunning advances in imaging such as 7T and functional MR imaging, surface and segmented anatomy, single-photon emission computed tomography (SPECT) scans, dopamine transporter (DAT) scans, and 3D quantitative volumetric scans.
Places 7T MR images alongside 3T MR images to highlight the benefits of using 7T MR imaging as it becomes more widely available in the future.
Presents essential text in an easy-to-digest, bulleted format, enabling imaging specialists to find quick answers to anatomy questions encountered in daily practice.
Includes the Expert Consult™ version of the book, allowing you to search all the text, figures, and references on a variety of devices.

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Randomised Clinical Trials: Design, Practice and Reporting 2nd Edition

Randomised Clinical Trials: Design, Practice and Reporting 2nd Edition

Randomised Clinical Trials: Design, Practice and Reporting provides a detailed overview of the methodology for conducting clinical trials, including developing protocols, data capture, randomisation, analysis and reporting. Assuming no prior background, this user-friendly resource describes the statistical, regulatory, and practical components required for conducting randomised clinical trials. Numerous examples and case studies from industry, academia, and the research literature help readers understand each stage of the clinical trial process.

This second edition contains extensively revised material throughout, including new chapters covering designs for repeated measures, non-inferiority, cluster and stepped wedge trials. Other new chapters describe data and safety monitoring, biomarker studies, and feasibility studies. Updated and expanded sections discuss situations where multiple organs, different body locations or competing risks are involved, subgroup analysis, and multiple outcomes. Written by an author team with extensive experience in conducting clinical trials, this book:

  • Provides comprehensive coverage of randomised clinical trials, ranging from basic to advanced
  • Features several new chapters, updated case studies and examples, and references to changes in regulations
  • Explains basic randomised trials, including the parallel two-group controlled trial with a single outcome measure
  • Covers paired trial designs and trials with more than two interventions
  • Includes a chapter on miscellaneous topics such as adaptive designs, large simple trials, Bayesian methods for very small trials, alpha-spending functions and the predictive probability test

Randomised Clinical Trials is essential reading for clinicians, nurses, data managers, and medical statisticians involved in clinical trials, and for health practitioners responsible for direct patient care in a clinical trial setting.

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The Peripheral T-Cell Lymphomas 1st Edition

The Peripheral T-Cell Lymphomas 1st Edition

THE PERIPHERAL T-CELL LYMPHOMASProvides a comprehensive look at Peripheral T-Cell lymphomas, including the group’s unique geographic distribution, underlying genetics, and novel treatments

Peripheral T-Cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represent 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat.

For the first time in a single volume, The Peripheral T-Cell Lymphomas presents a comprehensive survey of this complex and rare group of blood cancers. Featuring contributions from an international team of leading authorities in the various aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource:

  • Covers the biological basis, epidemiology, classification, and treatment of PTCL
  • Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL
  • Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation
  • Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations
  • Features contributions from the Chairs The T-Cell Lymphoma Forum: the world’s largest meeting focused on PTCL

Reflecting the unique epidemiology and genetic diversity of the PTCL, The Peripheral T-Cell Lymphomas is an indispensable source of data, insight, and references for the medical community, particularly oncologists and hematologists in both training and practice.

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Bone and Joint Infections: From Microbiology to Diagnostics and Treatment 2nd Edition

Bone and Joint Infections: From Microbiology to Diagnostics and Treatment 2nd Edition

BONE AND JOINT INFECTIONS

Explore this comprehensive presentation of bone and joint infections, including non-implant and implant-associated orthopedic infections

In the newly revised Second Edition of Bone and Joint Infections: From Microbiology to Diagnostics and Treatment, accomplished researcher and author Werner Zimmerli delivers a comprehensive overview of the most recent developments in the subject of bone and joint infection. Covering much of the new information appearing over the last five years, the book includes four new chapters presenting the diagnostic approach in bone and joint infections, discussing the identification of pathogens by non-culture techniques, management of multi-resistant bacteria in bone and joint infections ­by bacteriophages, and unusual microorganisms in periprosthetic joint infections.

Many of the chapters are also updated to include new information on topics like eubacterial PCR, multiplex PCR, and the shotgun metagenomics approach. These subjects are of increased applicability and interest to increase the fraction of cases with identified pathogens. The book also helps clinicians to understand MRI-based images and rapidly interpret and plan for comprehensive therapy.

Readers will also benefit from the inclusion of:

  • A thorough introduction to the pharmacokinetics and pharmacodynamics of antibiotics in bone and preclinical models of infection in bone and joint surgery
  • An exploration of native joint arthritis in children and adults, as well as an overview of septic arthritis of axial joints
  • A practical discussion of the general aspects of periprosthetic joint infection, as well as specific aspects of periprosthetic joint infection after total hip and knee, shoulder, elbow, and ankle arthroplasty
  • A concise treatment of osteomyelitis in children and adults

Perfect for infectious disease specialists, microbiologists, orthopedic and trauma surgeons, and internists, Bone and Joint Infections: From Microbiology to Diagnostics and Treatment will also earn a place in the libraries of professionals working in the implant industry and pharmaceuticals, as well as clinical pharmacologists and rheumatologists.

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Practical Thoracic Pathology: Diseases of the Lung, Heart, and Thymus First Edition

Practical Thoracic Pathology: Diseases of the Lung, Heart, and Thymus First Edition

Extensively revised and expanded, Practical Thoracic Pathology: Diseases of the Lung, Heart, and Thymus (formerly Practical Cardiovascular Pathology ) is a superbly illustrated, one-volume reference to pathology of the thorax. More than 1,000 full-color illustrations, tables, and “practical points” boxes help you arrive at a diagnosis accurately and efficiently. Ideal for both pathology residents and practicing surgical pathologists, this in-depth resource focuses on illustrated practical diagnosis, including differential diagnosis.
Key Features:

  • New globally-recognized editors and contributors share their expertise in every area of thoracic pathology.
  • The significantly revised cardiac section has been reorganized and rewritten to reflect current treatments and terminology, while retaining its practical approach emphasizing clinical and pathologic correlation.
  • Objective coverage includes updated classifications of interstitial lung disease, vascular lung disease, transplant rejection, autoimmune diseases, and carcinomas of the lung, as well as non-epithelial tumors.
  • Up-to-date information on the genetics of lung cancer, with a focus on current guidelines for genetic testing and what likely lies ahead.
  • Superb coverage of imaging in interstitial lung disease, including explanations of radiologic findings that correlate with pathologic diagnosis.
  • Highly useful for residents, community pathologists, forensic pathologists, and academic pathologists, as well as subspecialty pathologists.

Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:

  • Complete content with enhanced navigation
  • Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web
  • Cross-linked pages, references, and more for easy navigation
  • Highlighting tool for easier reference of key content throughout the text
  • Ability to take and share notes with friends and colleagues
  • Quick reference tabbing to save your favorite content for future use

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An Introduction to Orthodontics 5th Edition

An Introduction to Orthodontics 5th Edition

Hailed as ‘superb’, ‘thorough’, and ‘contemporary’, this is the essential orthodontics text for all staff involved in orthodontic treatment, whether they are dental students, orthodontic therapists, postgraduate students at the beginning of their career, or more experienced clinicians wanting an evidence-based, concise update on the foundations of contemporary orthodontic care.

With over 700 illustrations and plenty of case studies, An Introduction to Orthodontics, Fifth Edition is a user-friendly introduction to the subject. Continuing its well-deserved reputation, it is the perfect starting point for learning key concepts and the practical aspects of orthodontics.

The new fifth edition has been completely updated to reflect contemporary practice, including a new chapter dedicated to hypodontia and orthodontics, and a new chapter on the fastest growing area in orthodontics, clear aligners.

Readers will find further reading and references at the end of each chapter, including references to appropriate Cochrane Reviews to aid revision and support clinical practice. Learning objectives, key points boxes, and instructive artwork make this an essential text for busy readers who need focused and practical learning.

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Psychiatry Board Review (Medical Specialty Board Review) 1st Edition

Psychiatry Board Review (Medical Specialty Board Review) 1st Edition

The field of psychiatry is evolving rapidly specifically in the areas of classification of many psychiatric disorders, psychopharmacology and psychotherapeutics. The new Diagnostic and Statistical Manual of Mental Disorders: DSM-5 which was introduced in 2013 forms the basis of the new classification system in psychiatry. The American Board of Psychiatry and Neurology is also in the process of phasing in DSM-5 criteria to the board examination, such that by 2017 the examination material will exclusively reflect the new manual. As psychiatric trainees and psychiatrists prepare for their certification and recertification examinations using the new classification system, a new board review textbook is imperative to address these changes in order to prepare them for the certification examinations as well as for their clinical practice. To help with this process we have compiled a list of 1000 questions and answers in psychiatry and neurology using the most current information
available in the field and using the DSM 5 classification system. This book has been specifically written for the busy professional who does not have the time to access numerous resources necessary to prepare for professional examinations.
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