Image-Guided Radiation Therapy (Imaging in Medical Diagnosis and Therapy) 1st Edition

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Image-Guided Radiation Therapy presents key image-guided radiation treatment (IGRT) technologies for external beam radiotherapy. The book explores the decades-long technological developments that have occurred in the realm of image-guided conformal, customized radiation treatment.

Expert authors, all of whom have actively participated in the development or implementation of IGRT, imaging, and enabling technologies, share their first-hand experiences on the science, clinical uses, and impact of these technologies. They describe kilovoltage and megavoltage imaging as well as radiological, ultrasound, and optical technologies for determining and validating target and patient positioning. The book examines how anatomical and biological imaging using CT and PET has contributed to the understanding of target volume boundaries and biological behavior. It also explores such innovations as 4D PET/CT and digital tomosynthesis.

Advancing patient care, this book focuses on a wealth of hybrid IGRT technologies and devices for coupled imaging and treatment inside the radiation treatment room. It thoroughly covers the modalities, software tools, and imaging treatment geometries that constitute IGRT.

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Neurobiology of Body Fluid Homeostasis: Transduction and Integration (Frontiers in Neuroscience) 1st Edition

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A timely symposium entitled Body-Fluid Homeostasis: Transduction and Integration was held at Araraquara, São Paulo, Brazil in 2011. This meeting was convened as an official satellite of a joint gathering of the International Society for Autonomic Neuroscience (ISAN) and the American Autonomic Society (AAS) held in Buzios, Rio de Janeiro. Broad international participation at this event generated stimulating discussion among the invited speakers, leading to the publication of Neurobiology of Body Fluid Homeostasis: Transduction and Integration.

Drawn from the proceedings and filled with rich examples of integrative neurobiology and regulatory physiology, this volume:

  • Provides updated research using human and animal models for the control of bodily fluids, thirst, and salt appetite
  • Explores neural and endocrine control of body fluid balance, arterial pressure, thermoregulation, and ingestive behavior
  • Discusses recent developments in molecular genetics, cell biology, and behavioral plasticity
  • Reviews key aspects of brain serotonin and steroid and peptide control of fluid consumption and arterial pressure

The book highlights research conducted by leading scientists on signal transduction and sensory afferent mechanisms, molecular genetics, perinatal and adult long-term influences on regulation, central neural integrative circuitry, and autonomic/neuroendocrine effector systems. The findings discussed by the learned contributors are relevant for a basic understanding of disorders such as heat injury, hypertension, and excess salt intake. A unique reference on the neurobiology of body fluid homeostasis, this volume is certain to fuel additional research and stimulate further debate on the topic.

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Medical Imaging: Technology and Applications (Devices, Circuits, and Systems) 1st Edition

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The book has two intentions. First, it assembles the latest research in the field of medical imaging technology in one place. Detailed descriptions of current state-of-the-art medical imaging systems (comprised of x-ray CT, MRI, ultrasound, and nuclear medicine) and data processing techniques are discussed. Information is provided that will give interested engineers and scientists a solid foundation from which to build with additional resources. Secondly, it exposes the reader to myriad applications that medical imaging technology has enabled.

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Role of Oxidative Stress in Chronic Diseases 1st Edition

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This book presents recent findings on the role of oxidative stress in chronic diseases. Understanding the mechanisms behind it enables readers to comprehend the rationale which underlies intervention in such conditions. The book places special emphasis on genetic polymorphism―an important issue related to this field of study. It covers the role of oxidative stress in transmissible disorders as well as non-transmissible chronic conditions with chapters on metabolic diseases, autoimmune and neurodegenerative diseases, and cancer and cachexia. Each chapter covers a different disorder and the efficacy of interventional procedures.

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Adipokines (Modern Insights Into Disease from Molecules to Man) 1st Edition

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Adipokines (also called adipocytokines) are a group of peptides secreted by adipose tissue. They have diverse roles, from functions in the individual cell to the whole body. This volume examines a wide range of specific adipokines as well as their general cellular aspects, including thermal stress and adipokine expression, central nervous system roles for adiponectin in neuroendocrine and autonomic function, and astroglial leptin receptors. It discusses related diseases and conditions such as nonalcoholic fatty liver disease, metabolic syndrome, heart and rheumatic diseases, and allergies and sleep disorders.

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Handbook of H+-ATPases 1st Edition

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This handbook on vacuolar and plasma membrane H+-ATPases is the first to focus on an essential link between vacuolar H+-ATPase and the glycolysis metabolic pathway to understand the mechanism of diabetes and the metabolism of cancer cells. It presents recent findings on the structure and function of vacuolar H+-ATPase in glucose promoting assembly and signaling. It also describes the regulatory mechanisms of vacuolar H+-ATPase in yeast cells, neural stem cells, kidney cells, cancer cells, and under diabetic conditions.

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Frontiers in Neutron Capture Therapy

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Frontiers in Neutron Capture Therapy contains current research results originally presented at the Eighth International Symposium on Neutron Capture Therapy for Cancer in La Jolla, CA. This comprehensive collection of peer-reviewed manuscripts is showcased in two volumes covering all aspects of the development of this multidisciplinary approach to cancer therapy. Volume I of this work includes clinical results and current progress in treatment planning, neutron sources and dosimetry, while Volume II presents the synthesis, pharmacology and tissue-targeting design of boron compounds, including work on preclinical dosimetry and radiobiology.
Intended for researchers and clinicians involved with or interested in new modes of cancer therapy, this volume will also serve as a useful guideline for scientists, students, and practitioners in the field.

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Breast Imaging

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This book constitutes the refereed proceedings of the 13th International Workshop on Breast Imaging, IWDM 2016, held in Malmö, Sweden, in June 2016.

The 35 revised full papers and 50 revised poster papers presented together with 6 invited talks were carefully reviewed and selected from 89 submissions. The papers are organized in topical sections on screening; CAD; mammography, tomosynthesis, and breast CT; novel technology; density assessment and tissue analysis; dose and classification; image processing, CAD, breast density, and new technology; contrast-enhanced imaging; phase contrast breast imaging; simulations and virtual clinical trials.

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Canine and Feline Skin Cytology

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This book discusses canine and feline skin cytology and the importance of this diagnostic tool in interpreting skin lesions. With more than 600 clinical and cytological color pictures, it explains the cytological patterns observed in all cutaneous inflammatory and neoplastic lesions in cats and dogs, as well as cutaneous metastasis of non-primary skin neoplasms. The first part of the book describes cell morphology and cytological patterns, providing an overview of the normal structure of the skin. In the second chapter, readers learn how to choose the best techniques for different types of lesions. Further chapters present the cytological findings in the main inflammatory and neoplastic skin diseases. By focusing on the macroscopic aspects of the lesions from which the cells are collected, it helps readers to interpret cytological specimens. The final chapter explores the cytology of cutaneous metastasis from internal organs or accessory glands. This book offers veterinary students and practitioners alike an essential diagnostic tool.

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Frontiers of Medicine

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In September 1925 the first class of medical students was admitted to the University of Rochester School of Medicine and Dentistry. On January 4, 1926 the Strong Memorial Hospital was officially opened. The first patient was admitted the next day. On January 7th Dr. John J. Morton, Jr., newly appointed Chief of Surgery, performed the first operation. Ten days later the first baby was delivered. From these small beginnings the University of Rochester Medical Center had a steady and strong growth into the internationally renowned center of teaching, research and patient care that it is today. In recognition of its semicentennial the Medical Center con­ ducted a series of events during the 1975 – 76 year in which medi­ cal faculty and staff~ alumni, community physicians and distin­ guished visitors participated. This symposium on “Frontiers of Medicine” was a climactic event of the year’s program. The twelve outstanding physicians and scientists undertook to look forward, in selected areas of biological science and medicine, to what promise there may be for developments to come which will significantly affect mankind’s health and the quality of life. Four areas were chosen for discussion to cover the span of human life and to include aspects of it which are of vital in­ terest and in which significant developments now seem to be prob­ able in the years ahead. So far as possible the presentations sought to cover the basic science, the clinical and the sociologic aspects of each subject area.

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