Prosthodontics at a Glance 1st Edition

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Prosthodontics at a Glance is a title in the popular At A Glance series and focuses on prosthodontics from diagnostics through treatment to post-operative maintenance. It is an ideal companion for all students of dentistry, clinicians and members of the dental team with an interest in prosthodontics.

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Pocket Prescriber Emergency Medicine 1st Edition

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Drug prescribing errors are a common cause of hospital admission, and adverse reactions can have devastating effects, some even fatal. Pocket Prescriber Emergency Medicine is a concise, up-to-date prescribing guide containing all the “must have” information on a vast range of drugs that staff from junior doctors to emergency nurses, nurse prescribers, paramedics and other pre-hospital providers may encounter in the emergency setting.

Key features:

• A–Z list of over 500 of the most commonly prescribed drugs with each entry containing the key prescribing information

• Safety issues, warnings, drug errors and adverse effects

• Practical guidance on drug selection, plus protocols and resuscitation guidelines

• Advice and reference information for complicated prescriptions

• Concise management summaries for common medical and surgical emergencies

• Essential advice for pain relief―from acute pain management to procedural sedation

• Clinically useful reminders of key facts from basic pharmacology to acute poisoning syndromes

Pocket Prescriber Emergency Medicine supplies all your information needs concerning commonly prescribed drugs at a glance, enabling on-the-spot decision-making to provide the highest standard of care whilst mitigating prescribing errors.

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Benefit-Risk Assessment Methods in Medical Product Development

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Benefit–Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments provides general guidance and case studies to aid practitioners in selecting specific benefit–risk (B–R) frameworks and quantitative methods. Leading experts from industry, regulatory agencies, and academia present practical examples, lessons learned, and best practices that illustrate how to conduct structured B–R assessment in clinical development and regulatory submission.

The first section of the book discusses the role of B–R assessments in medicine development and regulation, the need for both a common B–R framework and patient input into B–R decisions, and future directions. The second section focuses on legislative and regulatory policy initiatives as well as decisions made at the U.S. FDA’s Center for Devices and Radiological Health. The third section examines key elements of B–R evaluations in a product’s life cycle, such as uncertainty evaluation and quantification, quantifying patient B–R trade-off preferences, ways to identify subgroups with the best B–R profiles, and data sources used to assist B–R assessment. The fourth section equips practitioners with tools to conduct B–R evaluations, including assessment methodologies, a quantitative joint modeling and joint evaluation framework, and several visualization tools. The final section presents a rich collection of case studies.

With top specialists sharing their in-depth knowledge, thought-provoking considerations, and practical advice, this book offers comprehensive coverage of B–R evaluation methods, tools, and case studies. It gives practitioners a much-needed toolkit to develop and conduct their own B–R evaluations.

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Bayesian Designs for Phase I–II Clinical Trials (Chapman & Hall/CRC Biostatistics Series) 1st Edition

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Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources.

Bayesian Designs for Phase I–II Clinical Trials describes how phase I–II designs can serve as a bridge or protective barrier between preclinical studies and large confirmatory clinical trials. It illustrates many of the severe drawbacks with conventional methods used for early-phase clinical trials and presents numerous Bayesian designs for human clinical trials of new experimental treatment regimes.

The first two chapters minimize the technical language to make them accessible to non-statisticians. These chapters discuss the severe drawbacks of the conventional paradigm used for early-phase clinical trials and explain the phase I–II paradigm for optimizing dose, or more general treatment regimes, based on both efficacy and toxicity. The remainder of the book covers a wide variety of clinical trial methodologies, including designs to optimize the dose pair of a two-drug combination, jointly optimize dose and schedule, identify optimal personalized doses, optimize novel molecularly targeted agents, and choose doses in two treatment cycles.

Written by research leaders from the University of Texas MD Anderson Cancer Center, this book shows how Bayesian designs for early-phase clinical trials can explore, refine, and optimize new experimental treatments. It emphasizes the importance of basing decisions on both efficacy and toxicity.

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Infection Control for Advanced Practice Professionals

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Presents best practices for infection prevention and control in advanced practice Emphasizes team approach for infection control Case study provided for each chapter

——————————————————————————– This professional reference combines research on the best practices for infection control in clinical settings with essential information for advanced practice nurses and physician assistants. The book is organized by healthcare settings, and the coverage ranges from small practice offices to large hospitals and medical institutions. Each chapter is prefaced by a case study which is then incorporated into the theoretical material of the chapter as a continuing illustration. This format provides a reader-friendly instructional resource for advanced practice certifications and staff development.

From the Foreword

“At last is published a long-needed text for advanced practice nurses (APNs), providing them with the information essential to the care of essentially every patient they will encounter. Infection Control for Advanced Practice Professionals fills a void in the literature and recognizes the importance of a team approach to the prevention of infections in the variety of care settings in which APNs are practicing. The book is particularly timely and relevant because it appropriately places infection prevention solidly within the larger patient safety movement and affirms that preventing infections is everybody’s concern. In acute care settings, for example, infection control has occasionally been relegated to the infection prevention specialist (e.g., infection control nurse or hospital epidemiologist) or the infection control committee. This has shown to be ineffective in any setting. It is those who “touch” the patients and oversee their care who must assume the responsibility for preventing untoward events such as infections. While not all infections are preventable, there is indeed room for improvement. This comprehensive reference is a first and essential step in that direction!”

Elaine Larson, PhD, RN, FAAN, CIC Anna C. Maxwell Professor of Nursing Research Associate Dean for Research School of Nursing Professor of Epidemiology Joseph Mailman School of Public Health Columbia University Editor, American Journal of Infection Control

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Cultural Psychiatry (Advances in Psychosomatic Medicine, Vol. 33) 1st Edition

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Cultural Psychiatry with emphasis on its impact on etio-pathogenesis, diagnosis, clinical practice, preventive and research activities are topics discussed in this publication which give readers a general conceptual perspective of this field. Cultural aspects of psychiatric diagnosis in DSM-5 in particular and the current status of Cultural Psychiatry in European countries are discussed. Of unique importance to the field of psychosomatics are the reviews on so-called culture-bound syndromes and somatization and culture. Ethnopsychopharmacology, pharmacogenomics, current and future research perspectives in Cultural Psychiatry and bioethical dimensions of cultural psychosomatics are also reviewed. The volume closes with an epilogue and conclusions resulting from the examined topics. Psychiatrists, psychologists, social scientists and other mental health professionals involved in clinical practice and research groups as well as trainees and students will find that this publication provides a cogent perspective of current practice and research issues about a field that has enormous clinical relevance and which, until recently, has been systematically neglected.

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Clinical Atlas of ENT and Head & Neck Diseases 1 Pap/DVD Edition

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This atlas and text is a practical guide to otolaryngology for medical trainees. Divided into seven sections, each part is dedicated to a different area in the head and neck – nose, paranasal sinuses, pharynx, larynx, ear and neck, with a final section on endoscopy. Each chapter begins with the anatomy, physiology and pathology of the region, followed by detailed discussion on the investigation, diagnosis and treatment of associated diseases and disorders. The interactive DVD ROM includes four Powerpoint presentations, as well as videos of surgical procedures. 400 full colour images and illustrations enhance learning. Key points * Practical guide to ENT and head and neck diseases for trainees * Detailed discussion on each region of the head and neck, and associated diseases * Interactive DVD includes Powerpoint presentations and surgical videos * Includes 400 full colour photographs and illustrations

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Case History and Data Interpretation in Medical Practice: Case Histories, Data Interpretation, Pedigree, Spirometry

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This book has incorporated the techniques for a logical and accurate interpretation of the clinical information according to the modern examination system. The first edition of this book was published with the intention of helping students learn the basics of data interpretation and practice by themselves. Its huge popularity and wide acceptance among students has encouraged the author to upgrade the book and bring out this new edition enriched with new cases and pictures of a variety of clinical conditions. 100 new clinical cases have been added. The text contains variety in clinical setup, and the amount of data provided in each setup. Includes data on cardiac catheterization and a whole new chapter on pictorial diagnosis which contains 100 clinical pictures. Various modifications have been made in the book according to various innovative suggestions made by teachers and students. Incorporates many long and short questions with proper investigations, largely based on the real cases. Answers are given with brief short notes of the specific problems, so that the reader can get some idea without going through a big textbook. The book will help increase a doctors competence, and skill in diagnosing a particular disease, formulating specific investigations, and proper management. TABLE OF CONTENTS: I. Case History and Data Interpretation, II. Data Interpretation of Cardiac Catheter, III. Family Tree (Pedigree), IV. Spirometry, V. Pictures of Multiple Diseases.

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Conventional Nuclear Medicine in Pediatrics: A Clinical Case-Based Atlas 1st ed. 2017 Edition

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This superbly illustrated book combines the systematic approach of a textbook with the simplicity of consultation of an atlas in order to provide a comprehensive guide to the applications and benefits of scintigraphic studies in children. All of the clinical scenarios in which conventional nuclear medicine techniques frequently play a role in children are covered, with explanation of imaging diagnosis, the relevance of clinical history, problem solving, and pitfalls. The images themselves are the key focus of the book, and in each setting the added value offered by scintigraphy is carefully identified. The book also describes management of the pediatric patient and addresses general considerations, including reception, interaction with parents, radiopharmaceutical administration, image acquisition, radiation exposure, and the relationship of nuclear medicine and radiology. Since the child is not a young adult, it is insufficient simply to adapt nuclear medicine procedures performed in adults to the age and size of the child. Conventional Nuclear Medicine in Pediatrics will be a rich source of information for all who perform these procedures in the pediatric setting.

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