Atherosclerosis: Understanding Pathogenesis and Challenge for Treatment 1st Edition
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Monoclonal Antibodies: Methods and Protocols (Methods in Molecular Biology) 2nd ed
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Monoclonal Antibodies: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed modern approaches to isolate and characterize monoclonal antibodies against carefully selected epitopes. This edition includes new chapters covering the key steps to generate high quality monoclonals via different methods, from antigen generation to epitope mapping and quality control of the purified IgG. Chapters are divided into four parts corresponding to four distinct objectives. Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Monoclonal Antibodies: Methods and Protocols, Second Edition provides crucial initial steps of monoclonal antibody generation and characterization with state-of-the art protocols.
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Invisible Illness: Coping with misunderstood conditions
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Few books on invisible illness are written by psychologists. Based on work by the Chronic Illness Research Team (CIRT) at the University of East London, this expert, accessible book encourages people actively to manage their illness using the techniques shown. Based on 20 years of research Helps those often ‘written off’ by the medical profession Pioneering text on Mal de Debarquement Syndrome (MdDS) Authors specialist in chronic illness
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MCQs & Short Answer Questions for MRCOG: An aid to revision and self-assessment (Hodder Arnold Publication) 1st Edition
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This volume of practise true/false MCQs and short answer questions is intended to be used by the trainee obstetrician and gynaecologist as a self-assessment aid throughout training and during revision for the MRCOG examination, in particular Part 2. Questions have been carefully designed to test both theoretical and practical knowledge, and are representative of the curricular elements highlighted within the RCOG trainee logbook.
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Parkinson’s Disease: Diagnosis and Clinical Management, 2nd Edition 2nd Edition
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Parkinson’s disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson’s Disease: Diagnosis and Clinical Management comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson’s disease.
The book includes 23 completely new chapters, and has updated information on:
- Genetics
- Pathology
- Biomarkers
- Pathogenesis
- Impulse control disorders in Parkinson’s disease
- Updated outcome measures
- Complementary and alternative medicine for the treatment of Parkinson’s disease
Together the chapters form a comprehensive review of the many issues facing PD physicians today. Lucid and easily readable from beginning to end, each chapter may also stand on its own as a scholarly review of the individual subject. Each one is concisely written and heavily referenced for this purpose.
The second edition of Parkinson’s Disease: Diagnosis and Clinical Management provides a state-of-the-art review of where we’ve been, where we are now, and where we are going in treating this disease.
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Frontiers in Gynecological Endocrinology: Volume 1: From Symptoms to Therapies (ISGE Series) 2014th Edition
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This volume represents an up-to-date overview on the major areas of gynecological endocrinology, providing the reader with a complete explanation of female endocrine regulation and metabolism and relevant disorders and treatment. It is published within the International Society of Gynecological Endocrinology (ISGE) Series and is based on the 2013 International School of Gynecological and Reproductive Endocrinology Summer Course. The book covers a very wide range of topics – from primary amenorrhea to menopause, from the impact of ovarian surgery on fertility to fertility cryopreservation, from metabolic syndrome and polycystic ovary to premature ovarian failure and from the clinical impact of selective progesterone receptor modulators to the use of progesterone in prevention of premature labor. It will be an important tool for obstetricians and gynecologists, endocrinologists and experts in women’s health as well as interested GPs.
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Role of Apoptosis in Infection (Current Topics in Microbiology and Immunology) 2005th Edition
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Apoptosis is a regulated, energy-dependent process by which a cell se- destructs. This mechanism of programmed cell death plays an important role in normal development and control of cell numbers in mature a- mals. Apoptosis was initially defined by morphological criteria to describe the distinctive appearance of dying cells that developed nuclear conden- tion, cell shrinkage, and cytoplasmic blebbing. Initiation of the apoptotic process can come from external or internal stimuli and is highly regulated both by molecules that facilitate and by molecules that inhibit the process. Common features of apoptosis include activation of proteases and – cleases, mitochondrial membrane permeabilization, chromatin disruption, and translocation of phosphatidylserine from the inner to the outer s- face of the plasma membrane. Apoptotic cells attract phagocytes that – gulf the apoptotic bodies and prevent tissue damage in the region. Intense investigation of the cell death process has defined many molecular features of the pathway by which regulation and execution can be exploited by pathogens.
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Pathogenesis and Treatment of Acne and Rosacea 2014th Edition
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This book, written by experts from across the world, provides comprehensive coverage of acne and rosacea, focusing in particular on pathogenesis and treatment but also considering clinical aspects, prognostic factors, and impacts on quality of life. Both standard knowledge and important, clinically relevant insights that have emerged over the past decade are presented with the goal of assisting the reader in understanding these diseases and improving treatment outcome. It is explained how high-level research has recently given rise to a variety of new concepts in etiology and treatment, and emerging trends are also discussed. The book is in a reader-friendly format that highlights core messages with a very practical and clinical focus. Pathogenesis and Treatment of Acne and Rosacea will be an indispensable reference for all physicians who care for patients with acne or rosacea and for scientists working in the field.
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Melatonin and Melatonergic Drugs in Clinical Practice 2014th Edition
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The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This book contains chapters on the recent aspects of melatonin physiology, its receptors and their role in mitochondrial function, its immunomodulatory role and importance in seasonal dependent diseases, role in human reproduction, role in sleep, circadian rhythm and sleep disorders, role in neurologic disorders such as Parkinson’s disease, Alzheimer’s disease. Additionally, melatonin’s therapeutic use in neurobehavioral disorders in children, migraine and tension headache is also covered in this book. Melatonin’s antioxidant role in Duchenne’s muscular dystrophy and in glaucoma have also been discussed in short chapters. Two major melatonin agonists, ramelteon and agomelatine are discussed extensively on their current clinical application and ongoing research. Two chapters on agomelatonin and its role in mood disorders, particularly depressive disorders, are an important feature of this book. The chapters are written by experts from the global academia recognized for their original research and published work in the field of melatonin science.
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Nuclear Medicine: A Guide for Healthcare Professionals and Patients 2014th Edition
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The book is a compilation of guidelines from various organizations such as Society of Nuclear Medicine & Molecular Imaging, European Association of Nuclear Medicine, American College of Radiology and International Atomic Energy Agency. The description of the procedures is simple, easy to understand and current.
The aim of this book is:
a) Nuclear medicine professionals can use this book as a quick reference about how a procedure is to be performed. The set of instructions given to patient before, during and after the procedure have also been included in each chapter.
b) To educate general physicians about nuclear medicine procedures. The procedures are explained briefly with common indications and precautions. Normal and abnormal nuclear medicine images have also been included for quick comparison.
c) To educate paramedical staff or healthcare professionals so that they send patients to nuclear medicine department after proper preparation.
d) To educate patients who come for nuclear medicine procedure.
e) To clarify apprehensions and doubts which arise in the mind of the patients.
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