Male Hypogonadism: Basic, Clinical and Therapeutic Principles (Contemporary Endocrinology) 2nd ed. 2017 Edition

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Now in a revised second edition, this comprehensive text covers all aspects of male hypogonadism from the basic science to clinical management, comprehensively explaining and applying new insights to the treatment of hypogonadal men. Chapters covering neuroendocrine control of testicular function, Leydig cell function, spermatogenesis, and normal and delayed puberty open the book. The focus then turns to the pathophysiology and treatment of hypogonadism and other forms of testicular dysfunction, such as Klinefelter syndrome, cryptorchidism, and disorders of the pituitary, as well as reproductive and endocrine consequences of cancer treatment, environmental factors, obesity and aging. Next are chapters that describe the available options for androgen replacement therapy, and the outcomes when men with hypogonadism of various causes are treated with testosterone, as well as a chapter devoted to current approaches to stimulating spermatogenesis in gonadotropin-deficient men.

Highly practical and updated with the latest available data, this second edition of Male Hypogonadism: Basic, Clinical and Therapeutic Principles cogently presents a large body of scientific information on male reproductive endocrinology to provide a thorough understanding of the pathophysiology, clinical characteristics, and treatments for disorders that adversely affect testicular function.

From The New England Journal of Medicine

Male reproductive health has become an important focus of health services in many countries. Poor semen quality is a widespread problem, and both young and elderly men often seek medical advice regarding symptoms of hypogonadism, including sexual dysfunction. However, andrology — the clinical area of expertise that covers these medical problems — has not yet been given sufficient attention in the health care systems of most countries. Therefore, training of doctors in this medical discipline is often superficial and lacking in uniformity. This excellent book, edited by leading American andrologist Stephen J. Winters, covers most problems in this field. It is unavoidable that a book containing 19 chapters written by 37 contributors turned out somewhat uneven with regard to style and quality. However, the list of authors is impressive. They represent some of the best American, European, and Australian research groups in andrology. A clear benefit is the inclusion of information on topics that may be difficult to find in other books, such as the congenital cause of adult symptoms of hypogonadism and hypogonadism in congenital adrenal hyperplasia. The latter chapter should prove useful not only for endocrinologists treating patients with hypogonadism but also for urologists, since the “adrenal nests” in men with congenital adrenal hyperplasia can mimic malignant germ-cell tumors. The chapters on the effects of irradiation and chemotherapy are also important additions to the available literature. I also want to highlight the chapters on androgens, sex hormone-binding globulin, and androgen-replacement therapy. The editor himself is an internist, and perhaps his selection of information on the pediatric aspects of hypogonadism is less than comprehensive. A pediatric endocrinologist may miss information on the possibility of treatment of boys with hypogonadism with oral androgens and on the long-term outcome of the treatment of micropenis and male pseudohermaphroditism. Despite these minor criticisms, I recommend this book as a timely update for all endocrinologists and urologists who care for patients with hypogonadism, male infertility, or both. It will also be useful as an introduction to these medical specialties for doctors during their training years. Niels E. Skakkebaek, M.D.
Copyright © 2005 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS. –This text refers to an out of print or unavailable edition of this title

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Rapid Prototyping in Cardiac Disease: 3D Printing the Heart 1st ed. 2017 Edition

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This book provides an overview of the use of rapid prototyping in patients with cardiac pathology. With the exponential increase in the use of prototyping, or 3D printing technology, medical applications are becoming more widespread across specialties. Although medical centers are beginning to apply this technology for improved patient care, there is no single text to which specialists can refer for guidance about this emerging modality. The book discusses the use of rapid prototyping in medicine; model creation; image acquisition; rapid prototyping techniques; applications in congenital and structural heart disease; and development and management of a rapid prototyping service. The use of rapid prototyping for pre-procedural planning in patients with cardiac disorders such as septal defects, Tetralogy of Fallot, transcatheter aortic valve replacement, and ventricular assist devices and heart transplant significantly enhances visualization of cardiovascular anatomy. Rapid Prototyping in Cardiac Disease is a unique and valuable resource for cardiac imaging specialists, cardiothoracic surgeons, radiologists, and biomedical engineers.

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Musculoskeletal Diseases 2017-2020: Diagnostic Imaging 1st ed. 2017 Edition

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This book focuses on with musculoskeletal imaging: during the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors, internationally renowned experts in their field, have contributed chapters that are disease-oriented and cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As a result, this book offers a comprehensive review of the state of the art in musculoskeletal imaging. It is a valuable resource for general radiologists, radiology residents, rheumatologists, orthopaedic surgeons, and clinicians from other specialities wishing to update their knowledge in this discipline.

About the Author

Juerg Hodler is Professor of Radiology and chairman of the Dept. of Radiology at the University Hospital of Zurich, Switzerland. He started his career in 1990 at the University of California, San Diego where he was research fellow in Osteoradiology. Subsequently he completed a Master of Business Administration (MBA) at Heriot-Watt University, Edinburgh, Scotland. From 1992 to 2001 he has been chief of section at the Orthopedic University Hospital of Zurich, in 2001 he became chief at the Department of Radiology at the Orthopedic University Hospital of Zurich and in 2007 deputy medical director at the Orthopedic University Hospital Balgrist, Zurich. In 2010, he became a professor at the University of Zurich and was elected head of the Department of Radiology, University Hospital Zurich. He has peer-reviewed over 200 original papers (focusing on MR imaging of joints, MR-anatomical correlation, asymptomatic MR findings, clinical application of MR sequences) and written 28 book chapters and four books (including co-editing). He is course co-director of the International Diagnostic Course in Davos IDKD.

Rahel Kubik-Huch earned her medical degree and doctorate from the University of Zurich in 1991 and her titular professorship for diagnostic radiology in 2005. She completed her residency in diagnostic radiology at the University Hospital of Zürich, Switzerland, where she subsequently worked as senior physician. Since 2002 she has worked at the Kantonsspital Baden, Baden, Switzerland, where she was appointed head of the Institute of Radiology and director of the Dept. of Medical Services in 2005. In 2010, she also became a member of the executive board of the hospital. Her specialist focus is magnetic resonance tomography (especially breast, abdominal and genitourinary imaging) and breast imaging (all modalities, including breast MRI and interventions under imaging guidance). She has published numerous research articles in peer-reviewed journals, contributed to several book chapters and received a number of scientific awards, including the Swiss Society of Radiology Anniversary Award (“Jubiläumspreis”). She is a course co-director of the International Diagnostic Course Davos (IDKD), course advisor for the Breast Imaging Satellite Course, Pearl of the IDKD and a former organizer of the Advanced Breast and Pelvis Imaging Course at the ESMRMB where she has remained a member of the faculty.

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A Revised Consent Model for the Transplantation of Face and Upper Limbs: Covenant Consent

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This book supports the emerging field of vascularized composite allotransplantation (VCA) for face and upper-limb transplants by providing a revised, ethically appropriate consent model which takes into account what is actually required of facial and upper extremity transplant recipients. In place of consent as permission-giving, waiver, or autonomous authorization (the standard approaches), this book imagines consent as an ongoing mutual commitment, i.e. as covenant consent. The covenant consent model highlights the need for a durable personal relationship between the patient/subject and the care provider/researcher. Such a relationship is crucial given the recovery period of 5 years or more for VCA recipients. The case for covenant consent is made by first examining the field of vascularized composite allotransplantation, the history and present understandings of consent in health care, and the history and use of the covenant concept from its origins through its applications to health care ethics today. This book explains how standard approaches to consent are inadequate in light of the particular features of facial and upper limb transplantation. In contrast, use of the covenant concept creates a consent model that is more appropriate ethically for these very complex surgeries and long-term recoveries.

About the Author

James Benedict is a scholar who holds four advanced degrees, including two doctorates, the most recent being a Ph.D. in Health Care Ethics from Duquesne University in Pittsburgh, Pennsylvania. He co-authored a Bioethics Report on Informed Consent for Vascularized Composite Allotransplantation for the United States Department of Defense in 2013. He has also authored multiple units of health care ethics training material currently in use at health care institutions in Pennsylvania and Maryland. He has served as a clergyman in Pennsylvania, Ohio and Maryland, authored several scholarly and popular articles, adult education curriculum in theology and biblical studies, and contributed chapters to books on liturgy and church history. His current research interests include all aspects of transplantation ethics, from acquisition and allocation of organs and tissues to authorization of donation and consent to receiving tissues and organs and tissues. James is married, a father of three and a grandfather of four.

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Adult T-cell Leukemia/Lymphoma 1st ed. 2017 Edition

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This book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of non-Hodgkin lymphoma. Given the small number of patients, enrollment in clinical trials has not been feasible, and establishing treatment standard has been difficult but new evidence, such as results of nationwide studies on transplantation, have shown new insights and potential treatments. Based on recent evidence, the book presents new treatment methods for ATL and infection prevention of HTLV-1, enabling clinicians, researchers and post-docs specializing in hematology and virology to gain a valuable overview of the disease.

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USMLE Platinum Notes Step 2 Ck: The Complete Preparatory Guide 2nd ed. Edition

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USMLE Platinum Notes Step 1 and USMLE Platinum Notes Step 2 CK are the latest editions of these preparatory guides for the United States Medical Licensing Examination. Each book is entirely updated to equip students with the conceptual and clinical knowledge they need to score a 99 percentile in their exams. The first book, Step 1, is divided into seven chapters incorporating revision materials for anatomy, physiology, biochemistry, microbiology, pathology, pharmacology and biostatics. Step 2 CK incorporates clinical knowledge revision materials for medicine, paediatrics, psychiatry, dermatology, surgery, orthopaedics, ophthalmology, and obstetrics and gynaecology. These guides include USMLE type questions based on the latest exam format, clinical correlations and case scenarios, with revision questions at the end of every topic. USMLE Platinum Notes Step 1 and USMLE Platinum Notes Step 2 CK are enhanced by nearly 100 images and illustrations. Key Points – Latest edition of both USMLE Step1 and Step 2 preparatory notes – Previous editions published 2013 (9789350903414/9789350903421) – Revision questions, clinical correlations, clinical case scenarios – 96 images and illustrations

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Arbuscular Mycorrhizas and Stress Tolerance of Plants 1st ed. 2017 Edition

This book reviews the potential mechanisms in arbuscular mycorrhizas (AMs), in the hope that this can help arbuscular mycorrhizal fungi (AMF) to be more used efficiently as a biostimulant to enhance stress tolerance in the host plants. AMF, as well as plants, are often exposed to all or many of the abiotic and biotic stresses, including extreme temperatures, pH, drought, water-logging, toxic metals and soil pathogens. Studies have indicated a quick response to these stresses involving several mechanisms, such as root morphological modification, reactive oxygen species change, osmotic adjustment, direct absorption of water by extraradical hyphae, up-regulated expression of relevant stressed genes, glomalin-related soil protein release, etc. The underlying complex, multi-dimensional strategy is involved in morphological, physiological, biochemical, and molecular processes. The AMF responses are often associated with homeostatic regulation of the internal and external environment, and are therefore critical for plant health, survival and restoration in native ecosystems and good soil structure.

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Dermatology: Illustrated Study Guide and Comprehensive Board Review 2nd ed. 2017 Edition

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A fully-illustrated, note-packed volume of information, Dermatology: Illustrated Study Guide and Comprehensive Board Review fulfills a real need for a single study guide for the Dermatology Board Exam. Written by a previous Chief Resident of Dermatology at the University of Illinois at Chicago Medical Center, the text focuses on presenting comprehensive information in an easy-to-understand, easy-to-remember format.  The second edition of this incredibly popular book includes updated coverage of new medications, new entities, and over 300 additional full-color clinical and histological images. Following the layout of the successful first edition, even more tips, short lists, and tables, including mnemonics and memory tricks to mentally organize information fill every inch of this book – a must-have for any dermatologist and dermatology resident.

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Atlas of Peripheral Blood: The Primary Diagnostic Tool 1st Edition

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This book will be a full-color atlas of both benign and neoplastic proliferations in the blood. The book will illustrate the morphologic features on peripheral blood smears of the various disorders and the text will focus on diagnostic criteria, differential diagnosis and modern classification terminology. The book may be used as a stand-alone resource and should be useful to trainees and clinicians that routinely review peripheral blood smears. The book will be accompanied by an on-line image bank containing numerous additional full-color images of the various disorders.

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Holland-Frei Cancer Medicine 9th Edition

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Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients.

  • A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease
  • An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies
  • Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics
  • Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs
  • Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

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