Atlas of Lymph Node Pathology (Atlas of Anatomic Pathology)

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Atlas of Lymph Node Pathology reviews the histopathology of nodal diseases, illustrating the use of ancillary studies and includes concise discussions of pathogenesis, clinical settings and clinical significance of the pathologic diagnosis. The atlas features an overview of the benign reactive processes secondary to infectious, environmental or unknown insults, as well as relevant illustrations of virtually all primary and secondary neoplasms involving lymph nodes. The atlas also includes macroscopic images of some disorders, tables that help readers understand and comprehend diseases that look alike, and diagnostic algorithms for certain groups of diseases.

Authored by highly experienced pathologists, Atlas of Lymph Node Pathology is a valuable resource that illustrates the vast majority of diseases practicing pathologists, clinicians and oncologists are likely to encounter in daily practice.

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Computational Systems Pharmacology and Toxicology (Issues in Toxicology) Gld Edition

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The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental design, enable more rapid drug efficacy and safety testing and also reduce the number of animals used in experimentation. Rapid advances in availability of computing technology hold tremendous promise for advancing applied and basic science and increasing the efficiency of risk assessment.
This book provides an understanding of the basic principles of computational toxicology and the current methods of predictive toxicology using chemical structures, toxicity-related databases, in silico chemical-protein docking, and biological pathway tools. The book begins with an introduction to systems pharmacology and toxicology and computational tools followed by a section exploring modelling adverse outcomes and events. The second part of the book covers the discovery of protein targets and the characterisation of toxicant-protein interactions. Final chapters include case studies and additionally discuss interactions between phytochemicals and Western therapeutics.
This book will be useful for scientists involved in environmental research and risk assessment. It will be a valuable resource for postgraduate students and researchers wishing to learn about key methods used in studying biological targets both from a toxicity and pharmacological activity standpoint.

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Peptide-based Drug Discovery: Challenges and New Therapeutics Gld Edition

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With potentially high specificity and low toxicity, biologicals offer promising alternatives to small-molecule drugs. Peptide therapeutics have again become the focus of innovative drug development efforts backed up by a resurgence of venture funds and small biotechnology companies.

 

What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What are emerging therapeutics for peptide modalities? This book answers these questions with a holistic story from molecules to medicine, combining the themes of design, synthesis and clinical applications of peptide-based therapeutics and biomarkers. Chapters are written and edited by leaders in the field from industry and academia and they cover the pharmacokinetics of peptide therapeutics, attributes necessary for commercially successful metabolic peptides, medicinal chemistry strategies for the design of peptidase-resistant peptide analogues, disease classes for which peptide therapeutic are most relevant, and regulatory issues and guidelines.

 

The critical themes covered provide essential background information on what it takes to develop peptide-based medicine from a chemistry perspective and views on the future of peptide drugs. This book will be a valuable resource not only as a reference book for the researcher engaged in academic and pharmaceutical setting, from basic research to manufacturing and from organic chemistry to biotechnology, but also a valuable resource to graduate students to understand discovery and development process for peptide-based medicine.

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Pediatric Physical Therapy Fifth Edition

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Prepare your students for physical therapy practice with this up-to-date and accessible introduction to the major diseases and disabilities common to children who require physical therapy and the examination techniques and interventions commonly used in their rehabilitation. This fifth edition of Tecklin’s Pediatric Physical Therapy Pediatric Physical Therapy provides basic medical information regarding common clinical diagnostic categories, followed by coverage of physical therapy evaluation, treatment, and special issues within each diagnostic group. In addition, case studies accessible online at thePoint support the book’s strong focus on clinical decision-making.

Featuring new chapters on autism and obesity, new authors, the latest research, and much more, this fifth edition continues to provide just the right amount of information needed to prepare students for practice without overwhelming them with unnecessary detail. The fifth edition enables you to:

Extend your students’ learning online with robust learning resources, including:

  • A wide range of Case Studies that help students build their clinical decision-making skills
  • Anywhere, anytime access to the full book online

Save time planning and spend more time with your students with online Instructors’ Resources including:

  • PowerPoint slides
  • Image Bank

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Natural Products and Cancer Drug Discovery (Cancer Drug Discovery and Development)

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From the Back Cover

Mind Over Mood, Second Edition: Change How You Feel by Changing the Way You Think

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Discover simple yet powerful steps you can take to overcome emotional distress–and feel happier, calmer, and more confident. This life-changing book has already helped more than 1,000,000 readers use cognitive-behavioral therapy–one of today’s most effective forms of psychotherapy–to conquer depression, anxiety, panic attacks, anger, guilt, shame, low self-esteem, eating disorders, substance abuse, and relationship problems. Revised and expanded to reflect significant scientific developments of the past 20 years, the second edition contains numerous new features: expanded content on anxiety; chapters on setting personal goals and maintaining progress; happiness rating scales; gratitude journals; innovative exercises focused on mindfulness, acceptance, and forgiveness; 25 new worksheets; and much more.
Mind Over Mood will help you:
*Learn proven, powerful, practical strategies to transform your life.
*Follow step-by-step plans to overcome depression, anxiety, anger, guilt, and shame.
*Set doable personal goals and track your progress (you can photocopy the worksheets from the book or download and print additional copies).
*Practice your new skills until they become second nature.
Cited as “The Most Influential Cognitive-Behavioral Therapy Publication” by the British Association for Behavioural and Cognitive Psychotherapies and included in the UK National Health Service Bibliotherapy Program.

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Restless Legs Syndrome/Willis Ekbom Disease: Long-Term Consequences and Management 1st ed. 2017 Edition

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Due to the fact that Restless Legs Syndrome/Willis-Ekbom Disease is usually a chronic condition, this book aims to provide physicians with the necessary tools for the long-term management of patients with RLS. The first part of the book addresses the various comorbidities and long-term consequences of RLS on life quality, sleep, cognitive, psychiatric and cardiovascular systems, while the second part focuses on the management of long-term treatment and the drug-induced complications in primary RLS and in special populations. Written by experts in the field, this practical resource offers a high-quality, long-term management of RLS for neurologists, sleep clinicians, pulmonologists and other healthcare professionals.

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Endoscopic Spine Procedures 1 Har/DVD Edition

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From the Back Cover

Surface Tensions: Surgery, Bodily Boundaries, and the Social Self 1st Edition

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Surface Tensions is an expansive, yet intimate study of how people remake themselves after catastrophic bodily change―the loss of limbs, the loss of function, the loss or replacement of organs. Against a sweeping cultural backdrop of art, popular culture, and the history of science and medicine, Manderson uses narrative epistemology based on in-depth interviews with over 300 individuals to show how they re-establish the coherence of their bodies, identities, and biographies. In addition to offering important new insights into the care, rehabilitation, and rehabituation of post-trauma patients, Manderson’s work challenges conventional ideas about the nature of embodiment and is an important contribution to medical anthropology, disability studies, and cultural studies.

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Musculoskeletal Injuries and Conditions: Assessment and Management 1st Edition

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Musculoskeletal Injuries and Conditions: Assessment and Management is a practical guide to diagnosis and treatment of musculoskeletal conditions in clinical practice. More comprehensive than a handbook, yet more clinically-focused than a desk reference, this volume is a one-stop guide for clinicians who deal with musculoskeletal disorders and injuries in the practice setting.

The book is organized by anatomic region, from neck to toe, and written in outline format. Each chapter concisely presents the basic knowledge that every practitioner needs to have at the ready in the outpatient clinical context. Taking a uniform approach based on isolating symptoms and the location of the pain, the book presents a uniquely practical template for nonoperative management of a broad spectrum of musculoskeletal problems. All chapters include epidemiology, anatomy, biomechanics, physical examination, diagnostic studies, and treatment. Flowcharts for differential diagnosis and initial management are provided for chief complaints. Helpful tables, lists, and over 150 anatomic illustrations supplement the text throughout. Given the increasing importance of ultrasound in clinical decision-making at the point of care, a mini-atlas of normal and abnormal findings for common injuries is presented as part of the imaging work-up.

Designed to help busy practitioners diagnose and treat musculoskeletal disorders in the clinic or office, this book is an essential resource for physicians in rehabilitation and sports medicine, primary care, orthopedics, and other health care professionals who work in outpatient settings.

KEY FEATURES

 

    • Provides a consistent approach to managing common musculoskeletal conditions based on location of pain

 

    • Bulleted format and clear heading structure make it easy to find information
    • More than 30 flowcharts map out differential diagnosis, diagnostic approach, and initial management strategy for each complaint
    • Packed with useful tables, lists, and over 150 illustrations of surface anatomy
    • Integrates musculoskeletal ultrasound into the imaging workup, with over 40 normal and abnormal scans to aid in recognizing signature pathologies at the point of care

 

  • Purchase includes access to the fully-searchable downloadable e-book with image bank

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