Diagnosis and Endoscopic Management of Digestive Diseases: New Tools and Strategies

Diagnosis and Endoscopic Management of Digestive Diseases: New Tools and Strategies

In this book, leading international experts describe and discuss the various techniques available for the screening, diagnosis, management, and follow-up of digestive diseases, providing clinically useful, up-to-date reviews that draw upon their own experience and focus attention on the most recent advances in the field. Among the wide range of topics covered are the use of confocal laser endomicroscopy in the gastrointestinal tract, endoscopic suture systems, endoscopic submucosal dissection, per oral endoscopic myotomy, and cholangioscopy systems. The experience of a leading surgical group in the application of endoscopic radiofrequency ablation in pancreatic cancer is reported, and new surgical and endoscopic techniques for the treatment of Zenker’s diverticulum are proposed. The closing chapters examine the present and future of esophageal motility testing and the diagnostic yield of novel parameters in reflux monitoring. In addition to the discussion of techniques, advice is provided on training, endoscopy and imaging equipment, and set-up of endoscopy units during procedures.

 

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Practical Medical and Surgical Management of Chronic Rhinosinusitis

Practical Medical and Surgical Management of Chronic Rhinosinusitis

This book is a comprehensive compendium on the medical and surgical treatment of chronic rhinosinusitis (CRS), with or without polyposis. Detailed coverage is provided of a wide range of topics, including medical and surgical management of CRS and its subsets, medical therapy in the pre- and postoperative period and specific medical therapeutic classes currently employed in CRS patients. Each chapter highlights key aspects of specific therapies, including mechanism of action, indications, dosages, side-effects and available clinical efficacy data and emphasizes practical management pearls and pitfalls. Operative techniques for endoscopic sinonasal procedures for CRS are also outlined. The book will be a valuable resource for practicing general otolaryngologists, rhinologists and allergists as well as residents and fellows in training. It will also serve as a reference guide for physician assistants, nurse practitioners and nurses involved in the care of CRS patients.

 

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Pulmonary Complications of Non-Pulmonary Pediatric Disorders

Pulmonary Complications of Non-Pulmonary Pediatric Disorders

This book presents a systematic approach to the potential pulmonary complications of various systemic non-pulmonary pediatric disorders. Chapters focus on the pulmonary complications associated with: the major organ systems, types of disorders, metabolic conditions, and various modalities. Although specific diseases will be discussed, the main focus will be on describing the associated organ mechanisms and how they can negatively affect the respiratory system. Each chapter will also discuss methods of prevention, the diagnostic test(s) that may be necessary to diagnose or monitor these complications, and, if applicable, the recommended therapeutic modalities. Pulmonary Complications of Non-Pulmonary Pediatric Disorders provides pulmonologists, pediatricians, and other clinicians with a detailed, reliable explanation of seemingly unrelated signs and symptoms so they can form a more thorough differential diagnosis and prescribe the appropriate diagnostic tests and treatment.

 

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The Microbiome in Rheumatic Diseases and Infection

The Microbiome in Rheumatic Diseases and Infection

This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms in autoimmunity and the deeply related rheumatic diseases. This book comprehensively explains the emerging microbiome research through the interrelationships of biomedical sciences, including: immunology, microbiology, bioinformatics, and, with special emphasis, the clinical aspect of rheumatology. It examines the interplay between infectious organisms and major autoimmune diseases, including rheumatoid arthritis, psoriatic arthritis, juvenile arthritis, systemic lupus erythematosus, and vasculitis, and explains how to apply that knowledge to diagnostic techniques and treatment decisions. The international team of expert authors provides insight into current therapies and future interventions specifically targeting the microbiota and explores the impact of our deeper understanding on enhancing personalized medicine. The Microbiome in Rheumatic Diseases and Infection is an essential resource for rheumatologists, pediatricians, internists, microbiologists, and critical care providers caring for children and adults with rheumatic diseases.

 

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Pulmonary Manifestations of Pediatric Diseases E-Book

Pulmonary Manifestations of Pediatric Diseases E-Book

Pulmonary Manifestations of Pediatric Diseases is the first comprehensive, practical book strictly focused on diagnosing and treating the full spectrum of respiratory complications of non-pulmonary diseases. Pediatric pulmonologists and other expert specialists present their up-to-date and balanced perspectives on new approaches to therapy and recent advances on everything from HIV/AIDS and transplantation to postoperative complications. The contributors are some of the most distinguished and recognizable physicians in their fields giving you the benefit of accumulated insight and experience. You’ll have everything you need to perform a complete pulmonary consultation in one handy reference.

  • Details the key “need-to-know” facts for accurate diagnosis and therapy during pulmonary consultations.
  • Provides the latest updates on rapidly-changing topics, including HIV/AIDS, transplantation, and postoperative pulmonary complications.
  • Discusses current clinical controversies to provide perspectives on sensitive topics and offers the authors’ preferred approaches whenever relevant.
  • Features balanced coverage on each condition from a pediatric pulmonologist and other expert pediatric specialists.

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Pulmonary Manifestations of Rheumatic Disease, An Issue of Clinics in Chest Medicine

Pulmonary Manifestations of Rheumatic Disease, An Issue of Clinics in Chest Medicine

This issue brilliantly pairs a rheumatologist with a pulmonologist to explore each of the 14 article topics.  Topics include autoantibody testing, ultility of bronchoalveolar lavage in autoimmune disease, and pulmonary manifestations of such conditions as scleroderma, rheumatoid arthritis, lupus erythematosus, Sjogren’s Syndrome, Inflammatory Myopathies, and Relapsing Polychondritis.  The pulmonary vasculitities are discussed, as is antiphospholipid antibody syndrome, ankylosing spondylitis, and the impact of osteoporosis on pulmonary fuction.  Toxicity and monitoring of immunosuppressive therapy used in systemic autoimmune diseases is reviewed, as is lung transplantation in autoimmune diseases.

 

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Infections and the Rheumatic Diseases

Infections and the Rheumatic Diseases

This book provides a comprehensive and up-to-date review of the basic and clinical aspects of infections and infectious processes that trigger or aggravate a variety of autoimmune and inflammatory musculoskeletal disorders. It delivers a timely update on the interactions between infection and rheumatic diseases in order to provide clinicians with the tools they need for proper diagnosis and treatment.

The book is divided into five main sections. The first examines the basic aspects of bacterial infections with a discussion of molecular biology, the microbiome, various types of bacteria that cause infection, and recent advances in biologic therapy. The next section focuses on different forms of viral arthritis including hepatitis arthritis, arthritis associated with alpha viruses, and parvovirus-related arthritis. Subsequent chapters then discuss arthritis caused by mycobacteria, fungi, spirochete, and other miscellaneous arthritides. Following this are various analyzations on reactive arthritis and infection-related rheumatic diseases such as Whipple’s Disease, SAPHO Syndrome, rheumatic fever, and HIV-associated rheumatic manifestations. Finally, the book closes with three chapters on external impacts on infectious diseases such as climate change, vaccinations and systemic lupus erythematosus.

Infections and the Rheumatic Diseases is an essential resource for physicians and related professionals, residents, fellows, graduate students, and nurses in rheumatology, clinical immunology, and internal medicine.

 

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Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases

Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases

This book presents research outcomes, providing a big picture of rheumatic diseases as systemic conditions, and exploring the correlation between liver dysfunction and gastrointestinal lesions. Each chapter presents the association between major rheumatic diseases and hepato-gastrointestinal lesions, including liver and gastrointestinal involvement in lupus erythematosus, dermatomyositis, systemic sclerosis, Bechet’s disease, and IgG4-related disease. The chapters on PBC-CREST syndrome and immunosuppressive agents broaden readers understanding and enable them to view the diseases from a systematic perspective. Although the disease is rare, it has attracted considerable attention as an intractable disease, and despite the severity of the symptoms, little has been written on the topic. Adopting a multidisciplinary approach, this comprehensive volume thoroughly prepares readers for research in the field of systemic diseases. Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases is a valuable resource not only for hepatologists and rheumatologists, but also clinical residents and medical students.

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Rare Rheumatic Diseases of Immunologic Dysregulation

Rare Rheumatic Diseases of Immunologic Dysregulation

This book is a practical, user-friendly guide for diagnosing and treating patients with rare rheumatic diseases of immunologic dysregulation. Covering uncommon diseases such as IgG4-Related Disease, Castleman’s Disease, and Felty Syndrome, chapters aggregate information from case reports and anecdotal literature to create a single, comprehensive handbook for treating patients. Each chapter provides historical perspective and epidemiology; a literature review (including research trials, translational research, historical and current case reports, and case series); pathogenesis; clinical presentation; laboratory evaluation; imaging; histopathology; treatment; and outcomes. Rare Rheumatic Diseases of Immunologic Dysregulation is an invaluable resource for rheumatologists, rheumatology fellows, and clinical immunologists to better diagnose and treat patients with rare rheumatic diseases.

 

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Statistical Methods in Psychiatry and Related Fields

Statistical Methods in Psychiatry and Related Fields

Data collected in psychiatry and related fields are complex because outcomes are rarely directly observed, there are multiple correlated repeated measures within individuals, there is natural heterogeneity in treatment responses and in other characteristics in the populations.
Simple statistical methods do not work well with such data. More advanced statistical methods capture the data complexity better, but are difficult to apply appropriately and correctly by investigators who do not have advanced training in statistics. This book presents, at a non-technical level, several approaches for the analysis of correlated data: mixed models for continuous and categorical outcomes, nonparametric methods for repeated measures and growth mixture models for heterogeneous trajectories over time.
Separate chapters are devoted to techniques for multiple comparison correction, analysis in the presence of missing data, adjustment for covariates, assessment of mediator and moderator effects, study design and sample size considerations. The focus is on the assumptions of each method, applicability and interpretation rather than on technical details.

 

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