Category: Oncology

Head and Neck Oncology: A Concise Guide

Head and Neck Oncology: A Concise Guide

Head and Neck Oncology: A Concise Guide

This concise handbook has a unique approach and covers all important aspects of head and neck cancers from basic topics like carcinogenesis to advanced treatment options like Immunotherapy, Electrochemotherapy and robotic surgery in a succinct way. As every treatment centre manages its patients with different modality as per their institutional protocol, this book endeavors to standardize the processes by discussing the management of cancers of all anatomic areas in view of the National Comprehensive Cancer Network (NCCN) guidelines, which is the committee that prepares protocols for management of cancers and every head and neck oncosurgeon must adhere to these for their clinical practice.

Key Features

Explains the topics through flowcharts and diagrammatic representation which are helpful for exam preparation.

This book aims to serve as a valuable resource for post graduate residents of Maxillofacial surgery, ENT and otolaryngology, general surgery, plastic surgery and junior specialists.

Serves as a comprehensive, evidence based quick reference for the clinician on the go.

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Cancer Immunotherapy Principles and Practice, Second Edition

Cancer Immunotherapy Principles and Practice, Second Edition

Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer.

The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, Second Edition is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field.

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Soft Tissue and Bone Tumours: WHO Classification of Tumours 5th Edition

Soft Tissue and Bone Tumours: WHO Classification of Tumours 5th Edition

Soft Tissue and Bone Tumours is the third volume in the 5th edition ofthe WHO series on the classification of human tumours. This series (also knownas the WHO Blue Books) is regarded as the gold standard for the diagnosis oftumours and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise referencebooks provide indispensable international standards for anyone involved in thecare of patients with cancer or in cancer research, underpinning individualpatient treatment as well as research into all aspects of cancer causation,prevention, therapy, and education.

This volume will be of particular interest to pathologists, oncologists,surgeons, and epidemiologists who manage or research soft tissue and bonetumours. Sections are included on all recognized neoplasms of the soft tissueand bone, as well as on genetic tumour syndromes affecting these sites. Sincethe previous edition, there have been changes based on recent molecular andgenetic information, with impact on clinical practice.

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Skin Lymphoma: The Illustrated Guide 5th Edition

Skin Lymphoma: The Illustrated Guide 5th Edition

Skin Lymphoma: The Illustrated Guide 5th Edition

Easily misdiagnosed as benign skin diseases, malignant cutaneous lymphomas can present a variety of challenges to trainees and practicing specialists alike. Skin Lymphoma: The Illustrated Guide has been designed to alleviate some of these difficulties, providing all those working in the dermatological field with a complete and easily consulted text on this potentially fatal cancer. Authored by renowned dermatopathologist Professor Lorenzo Cerroni, its exhaustive contents cover the clinical presentations and pathological correlates of cutaneous lymphomas in their various forms, alongside their prognoses and strategies for treatment.

This expanded fifth edition features a wealth of enhancements and additions, including new chapters, updated content, and more than 1,300 full-color illustrations. Revised to reflect the most recent World Health Organization (WHO) and European Organization for Research and Treatment of Cancer (EORTC) classifications, its cutting-edge approach to its subject incorporates the latest molecular data, alongside more familiar histopathological and clinical features. The book’s considerable scope has been broadened into new and groundbreaking areas, the details of which are explored in chapters discussing primary cutaneous acral CD8+ T-cell lymphoma, composite lymphomas, and non-neoplastic cutaneous signs of systemic lymphomas, as well as in new sections on previously unexamined entities such as implant–associated anaplastic large cell lymphoma.

  • Fully updated with new genetic data and most recent WHO classifications
  • Contains four newly written chapters
  • Features unconventional presentation sections with commentary on diagnosis
  • Includes more than 1,300 color illustrations

Skin Lymphoma: The Illustrated Guide is an indispensable resource forclinical dermatologists, dermatopathologists, and any other medical practitioners and trainees involved in the diagnosis and treatment of skin lymphomas.

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Oncology (Mount Sinai Expert Guides)

Oncology (Mount Sinai Expert Guides)

Oncology (Mount Sinai Expert Guides)

The Mount Sinai Expert Guides provide quick access to point-of-care specialist clinical information for physicians across a range of therapeutic areas.

For each specialty area, the guides emphasize:

in order to summarize the very latest in diagnosis and management of diseases and related symptoms. Edited by renowned specialists from the Icahn School of Medicine at Mount Sinai, key faculty members provide the content for all chapters. To ensure consistency within each book and the series as a whole, chapters follow a unified structure throughout.

Bonus features such as online case studies with related questions for self-assessment, key patient advice, and ICD codes are provided via the series companion website.

Each guide also has its own mobile app available for purchase, allowing you rapid access to the key features wherever you may be.

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Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies

Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies

Drug Resistance in Colorectal Cancer

Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug resistance occurs during chemotherapy. In addition, users will find the current therapeutic strategies used by clinicians in their practice in treating colorectal cancer. The combination of conventional anticancer drugs with chemotherapy-sensitizing agents plays a pivotal role in improving the outcome of colorectal cancer patients, in particular those with drug-resistant cancer cells.

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From a clinical point-of-view, the content of this book provides clinicians with updated therapeutic strategies for a better choice of drugs for drug-resistant colorectal cancer patients. It will be a valuable source for cancer researchers, oncologists and several members of biomedical field who are dedicated to better treat patients with colorectal cancer.

  • Presents a systemic summary of molecular mechanisms for a quick and in-depth understanding
  • Updates current trends in the field with pioneering information on drug resistance
  • Encompasses both basic and clinical approaches for a better understanding of unsolved problems from a holistic point-of-view

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Physicians’ Cancer Chemotherapy Drug Manual 21st Edition

Physicians’ Cancer Chemotherapy Drug Manual 21st Edition

Physicians’ Cancer Chemotherapy Drug Manual 21st Edition

Completely revised and updated for 2021, the Physicians’ Cancer Chemotherapy Drug Manual is an up-to-date guide to the latest information on standard therapy and recent advances in the field. Written by world-class experts in clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens―both on- and off-label―for the treatment of all the major cancers.

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Key Features: • Addition of 16 new agents and several new supplemental indications that have all been approved by the FDA within the past year • Updated new indications for previously approved agents • Indications, drug doses and schedules, toxicities, and special considerations for each agent expanded and revised • A specific chapter focused on antiemetic treatment regimens for both acute and delayed nausea/vomiting • Diagrams of drug structures and pathways for many of the agents • A comprehensive discussion of clinical pharmacology, special considerations, indications, and dosages • Covers toxicity and drug–drug interactions • A section on chemotherapy regimens for all major cancers • Provides an overview of the basic principles of cancer drug therapy

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Locoregional Radionuclide Cancer Therapy

Locoregional Radionuclide Cancer Therapy: Clinical and Scientific Aspects 

Locoregional Radionuclide Cancer Therapy

This book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy includes a diversity of choices of well characterized biochemical and physiologic target molecules. The delivery and retention of radionuclides may be monitored by advanced imaging for exact tissue localization and for real-time dosimetry to enable personalized precision medicine. Radiopharmaceuticals in human cancer therapies are typically delivered in systemic routes but can also be designed for locoregional routes to harness pharmacokinetic advantages of higher payload and lower systemic toxicities. This book explores the latest advancements and clinical considerations of the locoregional approach.

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Throughout the chapters, the clinical and scientific bases of cancer treatment and the locoregional use of radionculides are explored. Mathematical models of radiation dosimetry of locoregional radionculdies on tissues are studied using common models for multiple commercially available radionuclides. Rodent and canine tumor models of LRCT are compared for selected radionuclides and radiopharmaceuticals. The practical aspects of radiopharmaceuticals production, marketing, transport, as well as radiation protection are reviewed. Finally, the combination of LRCT with immunotherapy and other cancer therapies and prospective future use of LRCT are discussed.

This is a guide for practicing nuclear physicians, interventional radiologists, radiation oncologists, radiation scientists, veterinarians and oncologists to expand their knowledge base and to prepare for designing locoregional radionuclide cancer therapies in animals and in humans.

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Applications of FDG PET in Oncology

Applications of FDG PET in Oncology: Best Clinical Practice

Applications of FDG PET in Oncology

This book provides up-to-date guidance on the use of FDG PET to assess the biological activity and treatment response of a wide range of malignancies, including, for example, lung cancer, breast cancer, head and neck cancer, gastrointestinal cancer, and malignant lymphoma. In the era of precision medicine, numerous new anticancer agents, such as molecular targeted agents and immune checkpoint inhibitors, have been developed to improve outcomes in cancer patients. FDG PET plays a key role in evaluating the effects of these novel treatments because it can detect changes in the metabolic activity of tumors before any reduction in their size is visible on other imaging modalities. Accordingly, FDG PET is of prognostic as well as diagnostic value, and allows prompt changes in patient management.

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The book is written by expert clinicians from Japan, where the universal public health insurance system ensures that FDG PET is widely used in routine oncological practice and cancer screening. It represents an unrivaled and comprehensive resource that will be of value for all healthcare professionals in the field of clinical oncology.

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