Apoptosis, Senescence and Cancer (Cancer Drug Discovery and Development) Softcover reprint of hardcover 2nd ed

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This book provides insight into established practices and research into apoptosis and senescence. The volume thoroughly examines novel and emerging techniques and research in the fields of cell death pathways, senescence growth arrest, drugs and resistance, DNA damage response, and other topics that still hold mysteries for researchers. In total, this volume provides basic scientists and clinicians with a deeper and more complete understanding of the cellular responses of malignancies which may determine the effectiveness of treatment, both in the initial stages of the disease as well as in disease recurrence.

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Palliative Care in Pediatric Oncology 1st ed. 2018 Edition

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Cancer and Chemoprevention: An Overview 1st ed

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Mechanisms of Carcinogenesis (Cancer Growth and Progression) 1989th Edition

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but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non­ or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco­ bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe­ reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.

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Cases in Head and Neck Cancer: A Multidisciplinary Approach 1st Edition

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Includes video and audio files! Cases in Head and Neck Cancer: A Multidisciplinary Approach encompasses rich material and resources that demonstrate the complex interface between the diagnostic and clinical information necessary to successfully manage patients with head and neck cancer. This must-read book contains cases written by leading experts in the field that cover a wide variety of head and neck cancers (i.e., tongue base, tonsil, laryngeal, HPV related, etc.) and treatment options, including minimally invasive surgery such as robotic surgery and combined modality treatment protocols. Specifically, this text addresses comprehensive cases from initial evaluation, diagnosis, imaging, and other physiological tests to multidisciplinary treatment management (surgery, chemotherapy, and radiation therapy). Additionally, approaches for the management of toxicities or morbidities of cancer treatment are presented, as well as care plans, discharge plans, and caregiver burden and survivorship issues. Moreover, material on health literacy, humanistic care, and improving communication with assistive technology has been included.
Written by clinicians specializing in speech-language pathology, otolaryngology, medical and radiation oncology, pathology, nurse case management, radiology, dietics, among other fields, this collection of authors provides one of the most complete presentations of the inner workings of the multidisciplinary care team.
The adult cases of head and neck cancer reviewed in this text exemplify current practice issues surrounding HPV, minimally invasive robotic surgery and combined modality treatments. Each author threads introductory comments throughout the cases illustrating the critical role of the speech-language pathologist, in particular, and how all clinicians must address coping with survivorship and caregiver burden issues.
Cases in Head and Neck Cancer intends to teach future medical practitioners how to approach the complexities associated with head and neck cancer. Its vast number of images and videos included on a PluralPlus companion website allow for experiential driven classroom activities. This text will be an invaluable resource for the education of speech-language pathologists, medical students, nurse care managers, dieticians, and any person involved in a head and neck cancer team.
The book includes access to 46 videos and 5 audio clips hosted on a PluralPlus companion website.
*Note Regarding Access to Supplementary Content Online: This book comes with related materials hosted on a PluralPlus companion website. If you purchase or rent a used copy of the printed book, the code to access the website printed inside the book may have been previously redeemed/used or be incorrect and you will NOT be able to use it. To guarantee access to the supplementary materials on the website, it is recommended you purchase a new/unsused copy of this book directly from Amazon or the publisher, Plural Publishing, Inc. If you purchase from other resellers, check with the reseller regarding the validity of the access code before completing your purchase. The publisher will not replace inactive access codes to customers renting or purchasing used books from Amazon or via other resellers.

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Precision Molecular Pathology of Hodgkin Lymphoma (Molecular Pathology Library) 1st ed. 2018 Edition

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This text provides a comprehensive and up-to-date overview of Hodgkin lymphoma. The volume reviews every facet of the cancer in great detail, including pathology, pathobiology, molecular genetics, microenvironment, epidemiology, treatment, and new therapeutic advances. The specific role of the lymphoma microenvironment is addressed, and the relationship of Hodgkin lymphoma to related non-Hodgkin lymphomas is covered as well.
Written by experts in the field, Precision Molecular Pathology of Hodgkin Lymphoma is a valuable resource for oncologists, surgeons, pathologists, clinical trainees, and investigators engaged in the diagnosis, treatment, and research studies of this lymphoid neoplasm.

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Skin Tumors and Reactions to Cancer Therapy in Children 1st ed. 2018 Edition

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In today’s era of genomic testing, targeted cancer therapies, and increased cancer survivorship, recognition and management of oncologic disease in children is becoming more important to address. This book familiarizes clinicians with the range of oncologic issues that pediatric dermatologists encounter, including the diagnosis and management of various skin tumors, cutaneous reactions to cancer therapies, and both acute and long term complications of cancer therapy.

Written and edited by experts in the field, Pediatric Skin Tumors and Cutaneous Reactions to Cancer Therapy explores these important topics, beginning with the discussion of various skin tumors, and associated genetic syndromes, followed by chapters on acute cutaneous reactions to traditional and targeted cancer therapies, graft versus host disease, and opportunistic skin infections. This book concludes with the discussion of both malignant and nonmalignant late effects of the skin in childhood cancer survivors.

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Early Breast Cancer: From Screening to Multidisciplinary Management

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Early Breast Cancer presents a wide-ranging analysis of diagnosis, pathology, and multidisciplinary management of the patient presenting with early breast cancer for radiologists, pathologists, surgeons, and medical oncologists. The second edition is fully updated to include changes in perspective on such issues as screening and conservative surgery.

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HPV Infection in Head and Neck Cancer (Recent Results in Cancer Research) 1st ed

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This book is exceptional in presenting an interdisciplinary approach to the subject of human papillomavirus (HPV) infection in the context of head and neck cancer. Leading experts in the field discuss the epidemiology and molecular biology of HPV-positive head and neck squamous cell carcinoma, HPV testing, the nonsurgical and surgical treatment of HPV-positive tumors, predictive factors for outcome and quality of life, and ongoing trials on the effectiveness of vaccination in disease prevention. It also provides recommendations for testing, diagnosis treatment and vaccination. Otolaryngologists, head and neck surgeons, medical oncologists, radiation oncologists, molecular biologists and pathologists will find this book a valuable resource.

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Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity (Current Topics in Microbiology and Immunology) 1st ed. 2017 Edition

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This volume reviews the current state of research on immune checkpoints and offers novel concepts. It discusses the two most important immune checkpoints: T lymphocyte-associated antigen-4 (CTLA-4) and programmed cell death-1 (PD-1). It shows that antagonistic antibodies against these two molecules are highly effective in the treatment of various cancers and that PD-1 and CTLA-4 have been linked to the suppression of T-cell receptor signaling and co-stimulatory molecules. Further, the volume examines other agents, a number of cells, receptors and signaling molecules, that are also involved in the regulation of T-cell activation and extends the concept of immune checkpoints to “molecules and cells that negatively regulate T-cell activation”. Playing essential roles in immune homeostasis, they could offer new targets for cancer immunotherapy, and for the therapy of autoimmune diseases.

Written by internationally respected scientists, this book will appeal to basic scientists, clinicians, drug development researchers, and advanced students alike.

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