Category: Neurology/Neurosurgery

The Spectrum of Neuroendocrine Neoplasia

The Spectrum of Neuroendocrine Neoplasia

The Spectrum of Neuroendocrine Neoplasia

Neuroendocrine neoplasms comprise a large family of proliferative lesions that involve almost every part of the body. Our understanding of their cells of origin as well as the pathology, pathophysiology and genetics of these neoplasms has made tremendous advances in the last few decades. While they are often discussed as separate entities in textbooks of gastroenteropancreatic pathology and pulmonary pathology, their scope is much broader.

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The book conveys the similarities and differences of these fascinating tumors that may be found from the hypothalamus and pituitary to the rectum, and in soft tissue as well as in many organs. Written by experts in the field, the authors emphasize their structural, functional, predictive and prognostic features and attempt to provide the clinical context that allows improved diagnosis and therapy while building on the genetics that clarifies patterns of inheritance and predisposition to tumor development through precursor lesions.
The Spectrum of Neuroendocrine Neoplasia provides a broad overview of neuroendocrine neoplasms using a practical approach to diagnosis, histological classification and therapy, and presents the most important and significant developments of the technologies used to diagnose, classify and treat them.

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Operative Techniques in Epilepsy Surgery 2nd Edition

Operative Techniques in Epilepsy Surgery 2nd Edition

Operative Techniques in Epilepsy Surgery 2nd Edition

Epilepsy is a common neurological disorder affecting an estimated 1% of the population, about 20 to 30% of which experience seizures inadequately controlled by medical therapy alone. Advances in anatomic and functional imaging modalities, stereotaxy, and the integration of neuronavigation during surgery have led to cutting-edge treatment options for patients with medically refractory epilepsy. Operative Techniques in Epilepsy Surgery, Second Edition by Gordon Baltuch, Arthur Cukiert, and an impressive international group of contributors has been updated and expanded, reflecting the newest treatments for pediatric and adult epilepsy.

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Seven sections with 30 chapters encompass surgical planning, invasive EEG studies, cortical resection, intraoperative mapping, disconnection, neuromodulation, and further topics. Twelve cortical resection chapters cover surgical approaches such as amygdalohippocampectomy; hippocampal transection; frontal lobe, central region, and posterior quadrant resections; and microsurgery versus endoscopy for hypothalamic hamartomas. Disconnection procedures discussed in section five include corpus callosotomy, hemispherectomy, and endoscopic-assisted approaches. Well-established procedures such as vagus nerve and deep brain stimulation are covered in the neuromodulation section, while the last section discusses radiosurgery for medically intractable cases.

Key Highlights

  • Chapters new to this edition include endoscopic callosotomy, laser-induced thermal therapy (LITT), and focused ultrasound
  • High-quality illustrations, superb operative and cadaver photographs, radiologic images, and tables enhance understanding of impacted anatomy and specific techniques
  • The addition of videos provides insightful step-by-step procedural guidance

This is an essential reference for fellows and residents interested in epilepsy and functional neurosurgery, and an ideal overview for neurosurgeons, neurologists, and neuroradiologists in early career stages who wish to pursue this subspecialty.

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Surgery of the Brainstem

Surgery of the Brainstem 

The brainstem is one of the last bastions of surgical prohibition because of its densely packed ascending and descending tracts and nuclei carrying information to and from the brain. Although 10% of all pediatric tumors and 5% of all vascular anomalies occur in the brainstem, neurosurgeons have traditionally resisted dissecting lesions in this area. Recent advances in imaging, microscopy, anesthesia, and operative techniques have expanded the treatment paradigm for this most eloquent region of the brain.

Surgery of the Brainstem, by internationally renowned neurosurgeons Robert F. Spetzler, M. Yashar S. Kalani, and Michael T. Lawton, along with an impressive cadre of global experts, is a comprehensive guide to managing disorders of the brainstem, thalamic region, and basal ganglia. Organized in seven sections with 33 chapters, the text opens with four sections covering a variety of topics. Section I presents the history of brainstem surgery; Section II examines anatomy, development, and pathology; Section III reviews patient examination, imaging, and monitoring; and Section IV provides a succinct overview of surgical approaches. Sections V-VII cover a wide range of adult and pediatric tumors, ischemia, stroke, aneurysms, arteriovenous malformations, and cerebral cavernous malformations. More than 300 high-quality clinical images and medical illustrations enhance the text.

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Key Highlights

  • A full spectrum of treatment modalities and outcomes, including open surgery, endoscopic approaches, stereotactic radiosurgery, radiotherapy, endovascular techniques, and revascularization
  • An anatomy chapter featuring stunning Rhoton-style anatomical dissections delineates critical landmarks in the brainstem, thalamus, pineal region, and cranial nerves
  • Detailed discussion of patient positioning and exposure of various brainstem domains
  • Pearls on overcoming psychological, pathological, and anatomical barriers and managing complications

Understanding the basic anatomy, pathology, and clinical complexities of the brainstem and thalamic regions is essential for safe navigation and treatment. This remarkable book will provide neurosurgeons with additional insights on performing resections and achieving the best possible outcomes for patients with pathologic conditions in this delicate region.

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Sleep Neurology: A Comprehensive Guide to Basic and Clinical Aspects

Sleep Neurology: A Comprehensive Guide to Basic and Clinical Aspects

Sleep Neurology: A Comprehensive Guide to Basic and Clinical Aspects

This practical text provides knowledge of the basic neuroscience of sleep and sleep disorders as they interrelate with various neurologic conditions.

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Chapters in the first section cover neural networks involved in normal sleep processes, including dreams and memory. Also discussed are how these neural networks interact in various sleep stages and sleep disorders, such as sleep related movement disorders. The book’s second section explores the pathophysiology of sleep disorders in the  spectrum of neurologic conditions in both adults and children.  This includes sleep changes in patients with dementia, seizures, headaches, and stroke, and other common neurologic disorders.

Sleep Neurology fills an important gap in the sleep medicine literature by providing the underpinnings of sleep disorders and will be of great value to students, residents, and clinicians.

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Incidental Findings in Neuroimaging and Their Management

Incidental Findings in Neuroimaging and Their Management

Incidental Findings in Neuroimaging and Their Management

Incidental Findings in Neuroimaging and Their Management: A Guide for Radiologists, Neurosurgeons, and Neurologists presents a streamlined, case-based approach to 50 commonly seen incidental findings in neuroimaging. Edited by Kaye Westmark, Dong Kim, and Roy Riascos, this unique book provides the necessary knowledge to manage significant unexpected findings—from identification and analysis to efficacious interventions. With collaborative contributions from neuroradiologists, neurosurgeons, neurologists, otolaryngologists, body and musculoskeletal imaging experts, endocrinologists and hematologists/oncologists, this resource encompasses a wide spectrum of incidental findings.

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Organized by six sections, the book starts with normal variants that are extremely important to recognize in order to avoid unwarranted additional testing and unnecessary stress for the patient. Subsequent sections detail abnormalities that require extensive clinical evaluation in order to determine ideal management. These include incidental findings for extracranial, extra-spinal, intracranial, and intraspinal imaging. The final section outlines CT and MR imaging artifacts that are particularly concerning because they may mimic more dangerous pathologies while degrading imaging quality and obscuring real findings.

Key Features

  • Key findings and differential diagnosis are listed for each entity
  • Diagnostic decision trees present algorithms in an easy-to-understand manner
  • Artifact analyses explain the technical reason for each artifact and what can be done to mitigate effects
  • Clinical Q&As connect the radiologic diagnosis with actual case management decisions and provide in-depth background information that is applicable to management in various scenarios

This essential guide will help trainee and practicing neuroradiologists, neurosurgeons, and neurologists interpret incidental spine and brain imaging findings and make clinically informed, complex treatment decisions.

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Textbook of Pediatric Neurosurgery

Textbook of Pediatric Neurosurgery

Textbook of Pediatric Neurosurgery

This book documents the state of the art in pediatric neurosurgery with the intention of providing a comprehensive guide to the management of the full range of pediatric neurosurgical disorders that will aid in the delivery of optimal care. Detailed practical instruction, taking into account recent advances, is provided on the neurosurgical treatment of congenital brain malformations, cerebrovascular diseases, head injuries and spinal trauma, infections, functional disorders, congenital and developmental spinal disorders, and brain and spinal tumors. Pearls and pitfalls are highlighted, and attention drawn to the most useful tips and tricks.

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Information is also included on relevant related topics, including the principles of neuroimaging, the physiological responses of newborns, infants, and children to neurosurgical trauma, preoperative evaluation, anesthesiology and intensive care, and other forms of therapy. The authors are renowned experts in the field, and the text is supported by a wealth of high-quality images. Handbook of Pediatric Neurosurgery will be of value for neurosurgeons of all levels of experience, as well as for pediatricians, neuroradiologists, neuropathologists, and neuro-oncologists.

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Video Atlas of Neuroendovascular Procedures Illustrated Edition

Video Atlas of Neuroendovascular Procedures Illustrated Edition

Video Atlas of Neuroendovascular Procedures Illustrated Edition

Unlike traditional textbooks that detail natural history, physiology, and morphology, Video Atlas of Neuroendovascular Procedures presents basic and complex neuroendovascular procedures and cases with concise text and videos. Renowned neuroendovascular surgeons Leonardo Rangel-Castilla, Adnan Siddiqui, Elad Levy, and an impressive group of contributors have compiled the quintessential neuroendovascular resource. Organized into eight major subtopic sections, this superb video atlas covers a full spectrum of endovascular approaches to diagnose and treat intra- and extracranial neurovascular disease.

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The book starts with a section on vascular access and concludes with endovascular complications and management. Forty chapters includes succinct summaries, scientific procedural evidence, the rationale for endovascular intervention, anatomy, required medications, device selection, avoiding complications, and managing potential problems that can arise during procedures. The image-rich clinical cases feature insightful firsthand knowledge and pearls.

Key Features

  • More than 1,000 relevant, high quality neuroimaging findings and artist illustrations enhance understanding of impacted anatomy and approaches
  • Specific techniques and key steps are brought to life through more than 140 outstanding videos narrated by highly experienced endovascular neurosurgeons — conveniently accessible via smart phones or tablets using QR technology
  • Essential diagnostic procedures such as cerebral and spinal angiography, cerebral venogram, and balloon test occlusion
  • Complex neuroendovascular procedures including various angioplasty and stenting approaches for extracranial vessel disease, carotid and vertebral arteries, and venus sinus; thrombectomy procedures to treat acute ischemic stroke; and coiling, flow diversion, and embolization techniques for intracranial aneurysms, brain/spinal AVMs and fistulas, and select CNS and extracranial tumors

The content-rich reference is a must-have for all resident and veteran neurosurgeons, interventional radiologists, and neurologists. Learn to safely perform a wide array of cutting-edge neuroendovascular procedures — from access to closure — and achieve improved outcomes for your patients.

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Neurosurgery Outlines (Surgical Outlines)

Neurosurgery Outlines (Surgical Outlines) 

Surgery requires a combination of knowledge and skill acquired through years of direct observation, mentorship, and practice. The learning curve can be steep, frustrating, and intimidating for many medical students and junior residents. Too often, books and texts that attempt to translate the art of surgery are far too comprehensive for this audience and counterproductive to learning important basic skills to succeed. Neurosurgery Outlines by neurosurgeon Paul E. Kaloostian is the neuro-surgical volume in the Surgical Outlines series of textbooks that offer a simplified roadmap to surgery.

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This unique resource outlines key steps for common surgeries, laying a solid foundation of basic knowledge from which trainees can easily build and expand. The text serves as a starting point for learning neurosurgical techniques, with room for adding notes, details, and pearls collected during the journey. The chapters are systematically organized and formatted by subspecialty, encompassing spine, radiosurgery, brain tumors and vascular lesions, head trauma, functional neurosurgery, epilepsy, pain, and hydrocephalus. Each chapter includes symptoms and signs, surgical pathology, diagnostic modalities, differential diagnosis, treatment options, indications for surgical intervention, step-by-step procedures, pitfalls, prognosis, and references where applicable.

Key Features

  • Provides quick procedural outlines essential for understanding procedures and assisting attending neurosurgeons during rounds
  • Spine procedures organized by cervical, thoracic, lumbar, sacral, and coccyx regions cover traumatic, elective, and tumor/vascular-related interventions
  • Cranial topics include lesion resection for brain tumors and cerebrovascular disease and TBI treatment

This is an ideal, easy-to-read resource for medical students and junior residents to utilize during the one-month neurosurgery rotations and for quick consultation during the early years of neurosurgical practice. It will also benefit operating room nurses who need a quick guide on core neurosurgical procedures.

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Neurosurgery Case Review: Questions and Answers 2nd Edition

Neurosurgery Case Review: Questions and Answers 2nd Edition

Neurosurgery Case Review: Questions and Answers 2nd Edition

Neurosurgery Case Review: Questions and Answers, 2nd Edition by Remi Nader, Abdulrahman Sabbagh, Samer Elbabaa, Hosam Al-Jehani, Jaime Gasco, and Cristian Gragnaniello provides a robust study guide for the American Board Neurological Surgery and the Royal College of Physicians and Surgeons of Canada oral board examinations. The second edition expands on the highly successful first edition, presenting 148 cases commonly encountered by neurosurgeons in clinical practice.

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The cases are broadly divided into seven sections—tumor, vascular intracranial pathology, trauma, pediatric, functional, spine, and peripheral nerves. The chapters are arranged in a manner that mirrors the oral board exam. Each case includes a brief clinical scenario followed by questions on presentation, diagnosis, imaging, management, surgical detail, complications, and outcome. The presented information is backed by the latest available evidence-based references and data.

Key Features:

  • Contributions from internationally renowned neurosurgical educators
  • Detailed answers enhance readers’ knowledge and provide guidance on how to respond to questions asked in the oral board exams
  • More than 750 high-quality images, many in full color, ensure visual understanding of key concepts
  • Suggested readings at the end of cases offer additional study resources

This is an indispensable, one-stop resource for neurosurgical residents and fellows prepping for the ABNS and Royal College oral board examinations. Neurosurgeons studying for recertification will also find this book an invaluable reference for rapid review.

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Minimally Invasive Spine Surgery: A Primer

Minimally Invasive Spine Surgery: A Primer

Minimally Invasive Spine Surgery: A Primer

Minimally Invasive Spine Surgery: A Primer by Luis Manuel Tumialán is the ideal introduction to minimally invasive spine approaches, especially for neurosurgery and orthopedic residents, fellows, and spine surgeons who want to incorporate minimally invasive approaches into their practice. The Primer offers a treasure trove of 3D illustrations and animations that virtually brings the aspiring minimally invasive spine surgeon into the operating room alongside their professor. The text starts with a discussion of open spine surgery versus minimally invasive procedures and the optimal mindset required to convert from one to the other.

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The book is divided into lumbar, cervical, and thoracic spine sections, and a fourth section dedicated to the fundamentals of fluoroscopy and radiation exposure. The text begins with an overview, history, and evolution of each procedure, followed by a discussion of the anatomical basis for using a minimally invasive approach. Each anatomical section starts with the least complicated surgeries, thereby laying the foundation for more complex procedures discussed in subsequent chapters. The third section focuses on thoracic decompression, nerve sheath tumors in the lumbar and thoracic spine, and management of metastatic disease and intradural extramedullary lesions.

Key Features

  • Single-authored text provides uniform readability and philosophy—cover to cover
  • Lumbar approaches include microdiscectomy, laminectomy, transforaminal interbody fusions, and the transpsoas approach
  • Cervical procedures encompass posterior foraminotomy, laminectomy, and anterior discectomy
  • Superb illustrations, high-fidelity anatomical animations based on computer modeling, and procedural videos enhance understanding of minimally invasive spine principles

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