Category: Miscellaneous Medical Books

This volume presents a multidisciplinary synthesis of the literature in olfactory and gustatory cognition. Leading experts have written chapters on many facets of taste and smell, including odor memory, cortical representations, psychophysics and functional imaging studies, genetic variation in taste, and the hedonistic dimensions of odors. The approach is integrative, combining perspectives from neuroscience, psychology, anthropology, philosophy, and linguistics, and is appropriate for students and researchers in all of these areas who seek an authoritative reference on olfaction, taste, and cognition.

DOWNLOAD THIS BOOK FREE HERE

https://upsto.re/3vPFyHM

Mind-altering substances have been used by humans for thousands of years. In fact, ancient societies sometimes encouraged the consumption of drugs. Focusing on the archaeological study of how various entheogens have been used in the past, this volume examines why humans have social and psychological needs for these substances. Contributors trace the long-term use of drugs in ancient cultures and highlight the ways they evolved from being sacred to recreational in more modern times.

By analyzing evidence of these substances across a diverse range of ancient cultures, the contributors explore how and why past civilizations harvested, manufactured, and consumed drugs. Case studies examine the use of stimulants, narcotics, and depressants by hunter-gatherers who roamed Africa and Eurasia, prehistoric communities in North and South America, and Maya kings and queens.

Offering perspectives from many different fields of study, contributors illustrate the wide variety of sources and techniques that can provide information about materials that are often invisible to archaeologists. They use advanced biomolecular procedures to identify alkaloids and resins on cups, pipes, and other artifacts. They interpret paintings on vases and discuss excavations of breweries and similar sites. Uncovering signs of drugs, including ayahuasca, peyote, ephedra, cannabis, tobacco, yaupon, vilca, and maize and molle beer, they explain how psychoactive substances were integral to interpersonal relationships, religious practices, and social cohesion in antiquity.

DOWNLOAD THIS BOOK FREE HERE

https://upsto.re/3vMaqXS

The approach to drug discovery from natural sources has yielded many important new pharmaceuticals inaccessible by other routes. In many cases the isolated natural product may not be an effective drug for any of several reasons, but it nevertheless may become a drug through chemical modification or have a novel pharmacophore for future drug design. In summarizing the status of natural products as cancer chemotherapeutics, Anticancer Agents from Natural Products, Second Edition covers the:

• History of each covered drug―a discussion of its mechanism on action, medicinal chemistry, synthesis, and clinical applications
• Potential for novel drug discovery through the use of genome mining as well as future developments in anticancer drug discovery
• Important biosynthetic approaches to “unnatural” natural products

Anticancer Agents from Natural Products, Second Edition discusses how complex target-oriented synthesis―enabled by historic advances in methodology―has enormously expanded the scope of the possible. This book covers the current clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. It also reviews drug candidates currently in clinical development since many of these will be clinically used drugs in the future.

Examples include the drugs etoposide and teniposide derived from the lead compound podophyllotoxin; numerous analogs derived from taxol; topotecan, derived from camptothecin; and the synthetic clinical candidates, E7389 and HTI-286, developed from the marine leads, halichondrin B and hemiasterlin.

DOWNLOAD THIS BOOK FREE HERE

https://upsto.re/3vU96GS

“Health care is not failing but succeeding, expensively, and we don’t want to pay for it. So the administrations, public and private alike, intervene to cut costs, and herein lies the failure.”

In this sure-to-be-controversial book, leading management thinker Henry Mintzberg turns his attention to reframing the management and organization of health care.

The problem is not management per se but a form of remote-control management detached from the operations yet determined to control them. It reorganizes relentlessly, measures like mad, promotes a heroic form of leadership, favors competition where the need is for cooperation, and pretends that the calling of health care should be managed like a business.

“Management in health care should be about dedicated
and continuous care more than interventionist and episodic cures.”

This professional form of organizing is the source of health care’s great strength as well as its debilitating weakness. In its administration, as in its operations, it categorizes whatever it can to apply standardized practices whose results can be measured. When the categories fit, this works wonderfully well. The physician diagnoses appendicitis and operates; some administrator ticks the appropriate box and pays. But what happens when the fit fails—when patients fall outside the categories or across several categories or need to be treated as people beneath the categories or when the managers and professionals pass each other like ships in the night?

To cope with all this, Mintzberg says that we need to reorganize our heads instead of our institutions. He discusses how we can think differently about systems and strategies, sectors and scale, measurement and management, leadership and organization, competition and collaboration.

“Market control of health care is crass, state control is crude, professional control is closed. We need all three—in their place.”

The overall message of Mintzberg’s masterful analysis is that care, cure, control, and community have to work together, within health-care institutions and across them, to deliver quantity, quality, and equality simultaneously.

DOWNLOAD THIS BOOK FREE HERE

https://upsto.re/3vGfBvK

…one of the best scientific references available for acupuncture faculty and students….the author is able to effectively and efficiently bridge different approaches to auricular acupuncture as practiced in the western world for the past 50 years. — Doody’s Book Review (starred review)

The updated Second Edition of this outstanding reference guide and textbook provides a comprehensive review of both the French (after Nogier) and Chinese schools of acupuncture. The book offers a detailed description of the anatomy and morphology of the ear, acupoints on the ear and their localizations, as well as specific points for ear acupuncture. Dr. Rubach, with many years’ experience as a practitioner and teacher, provides valuable information in an easy-to-read, helpful format. You will learn how to use ear acupuncture safely and effectively. Large-format, graphic images are used to clearly show the location of points and the methods of auriculotherapy. The book includes answers to important everyday questions and is a treasury of practical information.

Special features of Principles of Ear Acupuncture, Second Edition:

• A critical review of different methods of stimulation
• A practical compendium of the therapeutic point combinations
• Quick reference section on acupoints and localization
• A question and answer section for instant review
• Now includes over 30 interesting indications

The book includes special sections on the use of acupuncture in pregnancy, obstetrics, gynecology, and dentistry. Filled with tips for daily practice and an excellent reference guide, this book is a must for students and ear acupuncturists.

DOWNLOAD THIS BOOK FREE HERE

https://upsto.re/3vnV9Mg

About the Author

About the Author

Through its use of real clinical examples, this book provides an explanation of the project management process tailored for nurses. It first describes, in detail, the project management process along with its relationship to the phases of the project life cycle. Coverage includes the tools available to successfully complete each phase of the project management process and advance the project life cycle. With the aid of case studies and project examples, the book then examines how to apply these principles in the day-to-day work of the nurse, whether manager, staff nurse, educator, researcher, or informatician.

DOWNLOAD THIS BOOK FREE HERE

https://upsto.re/3ER56w6

This volume focuses on the relationship between the regulation of signal transduction and disease mechanisms, and discusses how the dysregulation of intracellular signals cause diseases, cell death, carcinogenesis, and other disorders.

Growth, survival, transformation, and metabolic activities at the cellular level are regulated by various intracellular signal transduction pathways. Sources that stimulate intracellular signals include intracellular stresses and signal regulators/modulators, as well as extracellular growth factors. Recent studies on signal transduction analysis using animal and human cell lines have revealed how the intracellular signals are regulated and why their dysregulation leads to pathological states such as tumorigenesis, metabolic diseases, cell death, and so on.

This book highlights several important key molecules and intracellular signaling pathways such as microRNA, the TGF-beta signaling pathway, the Wnt signaling pathway and MET signaling pathway as topical and highly relevant issues in human cell research related to signal transduction. In addition to assessing the pathogenic role of these signaling pathways, it focuses on the molecular design of small molecule regulators/inhibitors of said pathways, one of the most important approaches in this area.

This book offers a valuable guide, helping not only research scientists but also clinicians to understand how the dysregulation of intracellular signals leads to diseases.

DOWNLOAD THIS BOOK FREE HERE

https://upsto.re/3EZAnQf