Category: General Practice

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The aim of this book is to dissect forensic anthropology and forensic pathology in its various and valuable contributions to contemporary society. It gives answers and approaches key questions to this sciences’ growing audience within different countries in the recent years. It aims to provide a practical approach to the investigation of bodies that are not fresh enough to be considered a normal forensic case. The specialists of both areas can have in a single book the useful tools and practical recommendations of these specialities (forensic anthropology and forensic pathology) that are spread among other textbooks.
It proposes original, illustrated, and updated articles on the four parameters of the biological profile; it discusses the factors of individualization; it explains the decay process of a body and the relevance of each step for forensic sciences, providing a useful approach to investigate such corpses; it reviews bone trauma; it facilitates the access to a number of international organizations and protocols related with the subject; and it compares the perspectives of expertises from different countries, namely Europe, North America, and Latin America. The majority of the authors found in this volume have quite a lot of experience with the subjects that they discuss. Finally, this book provides a bridge between forensic anthropology and forensic pathology, and brings practical advice from physical anthropology.
Forensic Anthropology and Medicine: Complementary Sciences From Recovery to Cause of Death presents both forensic anthropology and forensic pathology in their various and valuable contributions to contemporary society. Providing original, illustrated, and updated articles on the four parameters of the biological profile, this text encompasses the factors of individualization; the decay process of a body and the relevance of each step for forensic sciences; bone trauma; access to a number of international organizations; and protocols related with the subject, all with perspectives of expertise from different countries, namely Europe, North America, and Latin America.

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This concise and practical resource brings together recent advances in identifying and managing anemia of chronic disease (inflammation), genetically related anemia and anemia related to chronic end organ damage.  Chapters provide a detailed analysis of the current science of anemia, approaches to different patient populations, comorbid conditions and nutritional aspects of anemia. Novel therapies  focused on physiological pathways are introduced and discussed.  Controversies from the perspective of subspecialists focused in treating major causes of anemia within their specific disciplines are also presented.  Easy-to-reference and authored by experts in each clinical scenario, Management of Anemiais the launching point for learning more about this challenging and common condition.

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A fully updated new edition of this definitive, unrivalled, no-nonsense textbook, Central Pain Syndrome: Pathophysiology, Diagnosis and Management provides new treatment guidelines that aid the reader in effective management. • Encyclopedic coverage of all drug and surgical therapies, including the hot field of non-invasive and invasive cortical stimulation • 26 totally rewritten chapters include expanded sections on deep brain, spinal and other forms of stimulation, and a chapter on the efficacy of alternative and complementary medicine • Critical analysis of all current competing theories, including an expanded account of the leading dynamic reverberation theory which now incorporates a cortical attractor-based model • Clear-cut indications on drug usage, with black boxes for ineffective or dangerous drugs A classic textbook widely hailed on patients’ websites, this is key reading for medical specialists and trainees in pain management, neurology, neurosurgery and anesthesiology, as well as for patients

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Sepsis or septic shock is a type of condition/infection which represents one of the leading post-surgical or post-traumatic complications. Sepsis is the major cause of morbidity and mortality in intensive care units worldwide. Also, sepsis is the leading cause of death in non-coronary patients, with pulmonary sepsis accounting for most cases as it relates to lung dysfunction. This is a concise, practical softcover volume devoted to covering only the most practical information for physicians. Charts, tables, and other figures are used to illustrate easy-to-follow treatment guidelines for those professionals who regularly treat patients in the ICU.

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Published in 2014,  Protein Deimination in Human Health and Disease  was the first book on this novel post-translational modification, in which selected positively-charged arginine amino acids are converted to neutral citrulline amino acids by the peptidyl-arginine deiminase (PAD) family of enzymes. This area of research continues to expand rapidly, necessitating the need for this second edition. Chronicling the latest inflammatory, epigenetic, neurodegenerative, and carcinogenic processes,  Protein Deimination in Human Health and Disease, Second Edition, updates the latest advances in deimination research, including new information on PAD enzyme structure and activity, and how PAD knock-out animals are being used to study known and newly-discovered links to various human diseases.

The first edition outlined what was known about citrullinated proteins in normal tissues such as skin and hair, as well as in maladies such as rheumatoid arthritis (RA), multiple sclerosis (MS), Alzheimer’s disease (AD), glaucoma, peripheral nerve injury, neonatal hypoxic brain damage, and breast cancer. This second edition addresses numerous additional disorders such as diabetes, asthma, traumatic brain injury, inflammatory bowel disease, lupus, bone disease, heart failure, fronto-temporal dementia, and prostate and colon cancer. It also provides updates on the deimination research covering the three seminal diseases first linked to this process (RA, MS and AD), and details how auto-antibodies against citrullinated proteins contribute to disease. In addition, new hypotheses on the possible pathologic mechanisms of citrullinated myelin basic protein and glial fibrillary acidic protein are also proposed. This second edition also outlines the latest developments in therapeutic strategies, including the use of new PAD antagonists and innovative techniques such as micro-vescicles and stem cells as possible mechanisms to treat these conditions.

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