Category: Gastroenterology/Hepatology

Pancreatic Cancer: A Patient and His Doctor Balance Hope and Truth (A Johns Hopkins Press Health Book) 1st Edition

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Michael J. Lippe was diagnosed with pancreatic cancer in 2007. This is his story, and the story of pancreatic cancer, narrated by Lippe and Dr. Dung T. Le, the physician who is treating him.

In telling these stories, Lippe and Le alternate chapters. Lippe writes about the early signs that something was wrong; Le continues with a description of pancreatic cancer, its symptoms, and its treatments. Lippe talks about his prognosis, contemplates the prospect of death, and describes how he began to cope; Le explains the importance, for both doctor and patient, of balancing hope and truth. Lippe speaks frankly about the toll the disease takes on his marriage and family; Le offers a general picture of what most patients can expect with their illness. The book concludes with Lippe and Le’s reflections on their partnership in treating cancer, lessons they have learned, and their thoughts about the positive things that sometimes emerge from illness.

Pancreatic Cancer offers clear explanations of what the disease is, describes what people with the disease will feel physically and mentally, and discusses current treatments and future directions of research. The authors hope that their honest yet hopeful perspective will help all people with cancer and those who care about them.

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Nuclear Hepatology: A Textbook of Hepatobiliary Diseases

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Since the publication of the first edition of Nuclear Hepatology almost 10 years ago, new advances have taken place, both in our understanding of liver pathophysiology and various imaging modalities. A unique feature of imaging of physiology is that it enables quanti- cation. Since liver physiology is complex, quantification has been a challenge. Many p- lications in the past have often included quantification based on home-made software not available for others. Thus, the comparison of results from one center to another becomes difficult, if not impossible. The second edition of Nuclear Hepatology addresses these issues. Sophisticated software for liver and gallbladder function has been tested and va- dated through many of our previous publications. Now that software is FDA approved and available for others through a commercial company, it is hoped that future publications of imaging of liver and gallbladder physiology would routinely include quantification. Although the function of the hepatocyte is complex, it can be broadly divided into two main categories, substrate uptake at the basolateral border and intracellular transit prior to excretion into the canaliculi. The earliest manifestation of hepatocellular injury occurs in the form of prolongation of the intracellular transit time, which occurs long before the disruption of the basolateral border with subsequent rupture and death. The liver enzymes are released into circulation after the death of the hepatocyte.

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Signaling Pathways in Liver Diseases

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Patients suffering from HIV/AIDS often experience chronic pain due to the many diseases and infections they pick up as a result of a weakened immune system. It interferes with their quality of life and physical functioning, impacts adherence to antiretroviral therapy and HIV primary care, and is associated with significant psychological/social distress and substance use disorders.

Chronic Pain and HIV addresses all these complex issues that can influence pain care for the patient with HIV and acts both as a primer and a comprehensive review to define the field of chronic pain management. Using a clear, clinical approach, key topics include the following:

  • Musculoskeletal pain in individuals with HIV
  • Headache in individuals with HIV
  • Psychiatric comorbidities among individuals with HIV and chronic pain
  • Potential benefit and harm of prescription opioids in HIV
  • Pain at the end of life in individuals with AIDS
  • Treatment of chronic pain syndromes in the HIV–infected person.

Edited by an outstanding team with extensive experience in HIV/AIDS and pain/palliative care, every chapter is written by a world–famous expert in their field who provides a thorough review of the relevant literature, including the very latest in management guidelines from the leading international societies.

Perfect for all those in primary care, as well as infectious disease specialists managing patients with HIV/AIDS, Chronic Pain and HIV provides sensible, straightforward clinical advice to ensure the best possible patient management.

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Colorectal Surgery: Clinical Care and Management

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Using a case–based approach, Colorectal Surgery: Clinical Care and Management provides practical, clinical and expert guidance to illustrate the best care and clinical management of patients requiring colorectal surgery for colorectal disease.

Real–life cases illustrate the entire syllabus of GI/colorectal surgery, being specially selected to highlight topical or controversial aspects of colorectal care.  Cases have a consistent approach throughout and as well as outlining the actual management of each individual case, also offer an honest appraisal of the chosen management route, its successes and areas that could have been managed differently.   Pedagogic features such as learning and decision points boxes aid rapid understanding/learning, enabling the reader to improve their patient management.

In full colour and containing over 100 outstanding clinical photos and slides to support the cases, each section also covers recent developments/ landmark papers/ scoring systems and a thorough discussion of clinical management based on the major society guidelines from NICE, ASCRS and ECCO.

Reliable, well–written and perfect for consultation in the clinical setting,  Colorectal Surgery: Modern Clinical Care and Management is the perfect tool for all members of the multi–disciplinary team managing patients suffering from colorectal disease, specifically GI surgeons, gastroenterologists, oncologists and general surgeons.

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The Gastrointestinal System at a Glance 2nd Edition

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This concise introduction to the gastrointestinal system encapsulates the fundamental facts and principles of this rapidly growing and changing specialty. Written by experienced clinicians and teachers, the text covers the basic concepts of both the science surrounding the gastrointestinal system and the basics of clinical practice in an accessible, lucid format.

Now fully supported by a companion website at www.ataglanceseries.com/gastro containing interactive MCQs and downloadable digital flashcards, The Gastrointestinal System at a Glance is the ideal revision aid for medical and allied health students, and provides valuable insight for anyone seeking a comprehensive and concise guide to this subject area.

  • Fully revised and updated to include further coverage of diagnostic and therapeutic endoscopy, revised liver chapters and a new chapter on embryology
  • Now in full colour throughout
  • Supported by a companion website containing interactive self-assessment and digital flashcards – perfect for both study and revision
  • Provides an integrated approach to both the basic and clinical science of this core specialty

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Challenges in Colorectal Cancer 2nd Edition

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The latest guidance on challenging and controversial aspects of colorectal cancer

Colorectal cancer is one of the most common forms of cancer in the US and Europe. Thousands of people are diagnosed with the disease every year and nearly half of these die as a result. As colorectal cancer is curable when detected early, a significant proportion of these deaths could be prevented by earlier diagnosis.

Much has changed since the publication of the first edition of this book in 2001: introduction of screening programs, improved diagnosis and surgery for rectal cancer, and advances in adjuvant and palliative medical therapy to name but a few.

Challenges in Colorectal Cancer provides the most up-to-date information on the new and emerging treatments. The second edition looks at the total patient management of this condition and is aimed at the entire medical team caring for those with colorectal cancer. It also contains the latest guidelines on epidemiology and prevention of colorectal cancer, and the application of molecular genetics.

The expanded international editor team present advice on surgical management, including new laparoscopic and endoscopic techniques and the role of the pathologist. They also review hot topics in colorectal cancer treatment, including the role of radiotherapy, options for chemotherapy and new developments in vaccines and immunotherapy.

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Liver and Biliary Tract Surgery: Embryological Anatomy to 3D-Imaging and Transplant Innovations 2006th Edition

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This beautifully illustrated monograph provides an up-to-date and comprehensive overview about all fields of liver and biliary tract surgery and liver transplantation. It consists of four sections with 48 chapters: Section I: Anatomy, physiology, imaging and general principles, Section II: Biliary tract surgery, Section III: Liver surgery and Section IV: Liver transplantation. The book includes more than 500 figures and illustrations mostly in color. Some of the topics such as computer assisted surgery planning are treated comprehensively for the first time. The book is written in a concise and well conceived way.

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Zoom Gastroscopy: Magnifying Endoscopy in the Stomach 2014th Edition

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Since magnifying endoscopy of the stomach, or zoom gastroscopy, was first performed at the beginning of the 21st century , there have been numerous findings in the field worldwide. The author of this volume has developed a standardized magnifying endoscopy technique that enables endoscopists to constantly visualize the microanatomy (subepithelial capillaries and the epithelial structure) within the stomach. With this technology, it has become easy to obtain magnified endoscopic findings. Techniques differ, however, depending upon the endoscopist. Endoscopists around the world do not have a standardized magnifying endoscopy technique, which is mandatory for the scientific analysis of their findings. In addition, there is no logical explanation for how and which microanatomies are visualized by magnifying endoscopy with narrow-band imaging in the glandular epithelium of the stomach. This inconsistency results in considerable confusion among researchers and clinicians and a lack of terminology for the purposes of analysis. As magnifying endoscopy with narrow-band imaging (NBI) becomes more popular throughout the world, there is increased demand for a specialized reference book focused on this subject. The aims of the present volume, Zoom Gastroscopy: Magnifying Endoscopy in the Stomach, are manifold: (1) to illustrate the standard magnifying endoscopic technique that can visualize subepithelial mucosal microvessels as small as capillaries, the smallest unit of blood vessels in the human body, (2) to explain the optical phenomena and principles for NBI and its application to magnifying endoscopy, (3) to clarify which microanatomies are visualized by magnifying endoscopy with NBI and how this is achieved, and (4) to present a diagnostic system so called “VS classification system” for early gastric neoplasias. With a single author, the book consistently uses uniform anatomical terms to describe endoscopic findings, providing an essential reference for endoscopists in the world.

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The Health Professional’s HPV Handbook: Human Papillomavirus and Cervical Cancer 1st Edition

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This compact, illustrated handbook is a concise but comprehensive resource that introduces medical students, general medical practitioners and gynecologists to the significance of the human papillomaviruses in the etiology of cervical cancer. All chapters are fully referenced and written by experts in the field. The content review virus structure, the epidemiology of HPV, the latest advances in HPV vaccination, and new markers for cervical disease.

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Hereditary Colorectal Cancer: Proceedings of the Fourth International Symposium on Colorectal Cance

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Since the success in chemical induction of cancer in rabbit’s ear skin by K. Yamagiwa in 1915, oncologists of the world have come to believe that they can only solve their problems by means of animal experimen­ tation. The importance of environmental factors became moreevident in 1935 when T. Yoshida and T. Sasaki introduced azodye hepatocarcino­ genesis in rats. In the domain of the gastrointestinal tract, T. Sugimura has more recently accumulated enough evidence to indicate that locally active chemical mutagens are carcinogenic. In contrast, principal approaches to colorectal tumors have been quite different: emphasis has been placed on gene identification. Long before cancer of the large bowel was recognized, importance of the roles of adenomatosis coli and its familial occurrence attracted the attention of epidemiologists and geneticists. Morphological characteri­ zation and analysis of hereditary trends of human material have already bad a long history, and recently detailed analysis of genetic material has become feasible in the wake of rapid development in our knowledge of the oncoviruses, oncogenes, suppressor genes, chromosomal and DNA mapping, molecular mutation and so on. lt is true that in colorectal pathology, and in no other field, these areas of research have been explored more extensively and decisively. The identification of previ­ ously ill-defined lesions such as precancers and benign neoplasms have been improved because sequential changes can be observed in multiple samples spread over a wide area and followed up in due course.

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