Restless Legs Syndrome

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Although briefly covered in neurology texts, until now there has been no professional-level publication dedicated solely to restless legs syndrome (RLS). Most of what is available is either out-of-date or too general. Written by a panel of experts, Restless Legs Syndrome fills the void. Focusing on diagnosis and management, the authors discuss the epidemiology, pathophysiology and its clinical associations, and clinical features of RLS. They also explore how to correctly diagnose the many different types of patients who present with this disorder. The book’s discussions of the wide range of treatment options available gives clinicians the information they need to formulate appropriate pharmacological or non-pharmacological therapeutic regimens.

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Your Child in the Hospital: A Practical Guide for Parents

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Millions of parents take their child to the hospital each year for stitches, outpatient surgery, or longer stays for serious illnesses. Your Child in the Hospital: A Practical Guide for Parents is packed with sensible tips and home-grown wisdom that will make any visit to the hospital easier. It explains how cope with procedures, plan for surgery, communicate with doctors and nurses, and deal with insurance companies. Woven throughout the text are dozens of practical and encouraging stories from parents who have been through the experience of having a child in the hospital. This new edition contains a packing list, hospital journal for children, and helpful resources for parents.

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Sleep and Psychosomatic Medicine, Second Edition 2nd Edition

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Sleep and Psychosomatic Medicine presents an overview of sleep medicine and the management of common sleep disorders seen in a wide variety of practice settings.

Chapters have been written by experts in the field in order to provide physicians of a wide range of interests and abilities with a highly readable exposition of the principal results, including numerous well articulated examples and a rich discussion of applications.

The second edition has been revised to further broaden the scope with the inclusion of several new chapters such as Sleep and Dermatology, Fatigue in Chronic Medical Conditions, Occupational Sleep Medicine, Restless Legs Syndrome and Neuropsychiatric Disorders and Sleep Dysfunction after Traumatic Brain Injury, to name a few.

This second edition of Sleep and Psychosomatic Medicine is an interdisciplinary, scholarly, authoritative, evidence-based review of the field designed to meet the needs of a wide range of health care professionals, including psychiatrists, psychologists, nurses, medical students, and social workers in health care settings.

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Iron Metabolism: From Molecular Mechanisms to Clinical Consequences 4th Edition

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Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems  a natural target for  pathogenic microorganisms and parasites. Uniquely, humans  suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is  associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health.
The 4th edition of Iron Metabolism  is written in a lively style by one of the leaders in the field, presented in colour  and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.

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Affect Regulation Training: A Practitioners’ Manual 2014th Edition

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Emotion Regulation is currently one of the most popular topics in clinical psychology. Numerous studies demonstrate that deficits in emotion regulation skills are likely to help maintain various forms of psychological disorders. Thus, enhancing emotion regulation has become a major target in psychotherapeutic treatments. For this purpose, a number of therapeutic strategies have been developed and shown to be effective. However, for practitioners it is often difficult to decide which of these strategies they should use or how they can effectively combine empirically-validated strategies. Thus, the authors developed the Affect Regulation Training as a transdiagnostic intervention which systematically integrates strategies from cognitive behavior therapy, mindfulness-based interventions, emotion-focused therapy, and dialectical behavioral therapy. The effectiveness of ART has been demonstrated in several high-quality studies.

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Patient-Reported Outcomes: Measurement, Implementation and Interpretation

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Advancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for biopharmaceutical researchers and others in the health sciences community, it provides an up-to-date volume on conceptual and analytical issues of PRO measures.

The book discusses key concepts relating to the measurement, implementation, and interpretation of PRO measures. It covers both introductory and advanced psychometric and biostatistical methods for constructing and analyzing PRO measures. The authors include many relevant real-life applications based on their extensive first-hand experiences in the pharmaceutical industry. They implement a wealth of simulated datasets to illustrate concepts and heighten understanding based on practical scenarios. For readers interested in conducting statistical analyses of PRO measures and delving more deeply into the analytic details, most chapters contain SAS code and output that illustrate the methodology. Along with providing numerous references, the book highlights current regulatory guidelines.

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French’s Index of Differential Diagnosis An A-Z 16th Edition 16th Edition

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First published in 1912, French’s Index of Differential Diagnosis helps clinicians in the differential diagnosis of any condition which may be seen in hospital or general practice. Arranged alphabetically by symptom, the text helps readers identify each presentation, describes the different diagnoses that it could represent, and explains the tests used to make a diagnosis. Colour clinical photographs help with diagnoses at a glance.

The book is completely revised – many sections are largely rewritten, new ones added, diagnostic methods updated, many old illustrations replaced and others inserted. The emphasis, however, remains the same: the importance of a careful history, detailed clinical examination and the judicious use of laboratory and imaging investigations in the elucidation of the correct diagnosis. This reference is indispensable to medical students as well as trainee and established doctors in both general and hospital practice.

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Evidence-Based Clinical Reasoning in Medicine 1st Edition

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Medicine is still largely taught as an apprenticeship. Not until recently have medical students and physicians been taught to critically examine the evidence base behind many of our medical decisions, a rather astonishing fact when one stops to think about it.
While clinicians recognize that medicine is often practiced in an evidence-based void and with a touch of paternalism, the demands on a busy clinician to see patients often prevents them from taking the time to search the primary literature. This book addresses the most recent evidence behind diagnostic and management decisions of the most common inpatient diagnoses would therefore be valuable to medical students, residents, and hospitalists.
The book is perfect for students to help care for patients during their medicine subinternship rotation but may prove invaluable in preparation for their end-of-rotation NBME shelf examination.
This book it is case based, evidence based, clinically relevant, and extensively referenced.Edited by a clinically active hospitalist, which will help ensure the material remains clinically relevant and does not lean towards the esoteric.
Each chapter will also include Bottom Line and Take Home Point sections that will help the student process the points of primary importance discussed in the chapter.

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Reversibility of Chronic Degenerative Disease and Hypersensitivity, Vol. 3

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Encyclopedic in scope, Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 3: Environmental Manifestations of the Neurocardiovascular Systems draws deeply from clinical histories of thousands of patients. It focuses on clinical syndromes within the musculoskeletal, neurological, and cardiovascular systems with a special focus on vascular dysfunction and heart failure treatment.

The book explores mechanisms of chemical sensitivity and chronic degenerative disease, their manifestations, diagnosis, and approaches to reverse dysfunction. It covers a wide variety of topics including environmental sensitivity due to external pollutants, environmental control for reducing total body load, pollutant damage to vascular perfusion, altered blood volume, fluctuations of oxygen extraction, effects of endocrine on the vascular system, effects of pollutants on myocardial cells, and mechanisms in vascular damage.

The book also discusses in detail a wide variety of clinical manifestations including vasculitis, cardiac arrhythmias, cardiac metabolic syndrome, myocarditis, atherosclerosis, heart failure, urticaria, and anaphylaxis. Treatment for heart failure is also discussed. The third volume of a five-volume set, the book provides an essential resource for health care providers diagnosing and treating chemical sensitivity and chronic degenerative disease.

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