Category: Clinical Skills

The Plasticity of Skeletal Muscle: From Molecular Mechanism to Clinical Applications 1st ed

This book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis.

The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It also explains the roles of biological mediators such as PGC-1, transient receptor potential cation channels (TRPC), and AMPK in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome biogenesis, and redox regulation of mechanotransduction to modulate skeletal muscle mass are also covered.

It is an essential resource for physicians, researchers, post-docs as well as graduate students in the field of sports science including rehabilitation therapy, exercise physiology, exercise biochemistry, and molecular biology dealing with skeletal muscle.

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Essentials of Menopause Management: A Case-Based Approach 1st ed. 2017 Edition

Removing the shroud of complexity that  had engulfed the field of menopause research and management for more than a decade,  this unique, case-based resource discusses a range of topics relevant to the reproductive health of the aging female. The opening section includes chapters covering the symptomatology, epidemiology and impact of the menopausal burden, and reviews in depth the most current evidence on the efficacy, risks and benefits of pharmacological and alternative therapies. Utilizing vibrant case material, the second section details common symptoms of menopause and an individualized approach to management, such as sleep loss, skeletal fragility, sexual dysfunction, hirsutism and alopecia, primary ovarian insufficiency and failure, and vasomotor symptoms. Chapters reviewing therapeutic options and considerations tailored to gynecologic and breast cancer patients and survivors comprise the third and final section.

Developed as a multidisciplinary collaboration and addressing the needs of practicing reproductive medicine clinicians and researchers providing care to an aging female population, Essentials of Menopause Management provides clear, up-to-date information and recommendations on the range of current treatment strategies for menopause and its symptoms.

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Clinician’s Guide to Mycosis Fungoides 1st ed

Complete with dozens of color clinical photos to aid readers in diagnosis and treatment, this book includes TNM staging, description of the histopathology, and a step-by-step guide through the diagnosis of the disease. It is the most common form of cutaneous T-cell lymphoma, generally affecting the skin, though sometimes progressing internally over time. However, there is very little comprehensive information on this subject for dermatologists, dermatopathologists, and oncologists seeking deeper insight into this lymphoma in one all-inclusive text. Clinician’s Guide to Mycosis Fungoides meets this need, covering the history, categories of disorder, molecular analysis, etiology, epidemiology, effect on body systems, disorder symptoms, and treatment. Additionally, the various recommended treatments of mycosis fungoides are explained, using clinical research and case studies as guidance in part stemming from the author’s extensive research on the topic.

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Multiple Choice Questions in Pain Management 1st ed. 2018 Edition

This book presents current clinical knowledge relating to key topics in acute and chronic pain in a multiple choice question (MCQ) format. Individual chapters are devoted to subjects such as the anatomy of pain pathways, pain processing, evaluation of pain, different pain syndromes and pain involving different regions of the body, pharmacologic and physical pain management, neural blockade, and special procedures. Each of the MCQs has four or five answer options in true/false format, and the answers are discussed in detail with provision of suitable references whenever appropriate. Multiple Choice Questions in Pain Management will be especially valuable for those who are sitting anesthesia board exams anywhere in the world. It will, for example, meet the needs of candidates for the FRCA examination (in which 20–25% of MCQs relate to pain management) or the FFPMRCA examination (Fellowship of the Faculty of Pain Medicine of the Royal College of Anaesthetists). In addition, the book will be useful for pain fellows and for all clinicians who are seeking to improve their knowledge of pain management.

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Essentials of Interventional Techniques in Managing Chronic Pain 1st ed. 2018 Edition

This comprehensive review covers the full and latest array of interventional techniques for managing chronic pain.  Chapters are grouped by specific treatment modalities that include spinal interventional techniques, nonspinal and peripheral nerve blocks, sympathetic interventional techniques, soft tissue and joint injections, and implantables.  Practical step-by-step and evidence-based guidance is given to each approach in order to improve the clinician’s understanding.  Innovative and timely, Essentials of Interventional Techniques in Managing Chronic Pain is a critical resource for anesthesiologists, neurologists, and rehabilitation and pain physicians.

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A Treatise on Topical Corticosteroids in Dermatology: Use, Misuse and Abuse 1st ed. 2018 Edition

This treatise aims to fill up the lacuna and to contribute significantly to the dissemination of knowledge about the indication/contraindication, mechanism of action, ethical use, side-effects and various other facets related to topical corticosteroid.

Topical corticosteroids (TC) have greatly enhanced dermatologists’ ability to effectively treat several difficult dermatoses. The available range of formulations and potencies allows them to flexibly treat all groups of patients, different phases of disease, and different anatomic sites.

Improper/incomplete knowledge about topical corticosteroids’ mechanism of action, indications, classifications, and contraindications has produced a rapid rise in the incidence of improper use of these drugs, which could potentially bring disrepute to this entire group of amazing drugs.

Responsibility for disseminating proper knowledge regarding when, where, and how to use TC both to internists and patients primarily rests with dermatologists. In this regard, the benefits of rational and ethical use and the potential harm of overuse and misuse for nonmedical, especially cosmetic purposes, should be clearly conveyed before prescribing TC.

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Disease Control Priorities, Third Edition (Volume 9): Improving Health and Reducing Poverty 3rd Edition

As the culminating volume in the DCP3 series, volume 9 will provide an overview of DCP3 findings and methods, a summary of messages and substantive lessons to be taken from DCP3, and a further discussion of cross-cutting and synthesizing topics across the first eight volumes. The introductory chapters (1-3) in this volume take as their starting point the elements of the Essential Packages presented in the overview chapters of each volume. First, the chapter on intersectoral policy priorities for health includes fiscal and intersectoral policies and assembles a subset of the population policies and applies strict criteria for a low-income setting in order to propose a “highest-priority” essential package. Second, the chapter on packages of care and delivery platforms for universal health coverage (UHC) includes health sector interventions, primarily clinical and public health services, and uses the same approach to propose a highest priority package of interventions and policies that meet similar criteria, provides cost estimates, and describes a pathway to UHC.

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Fungal Allergy and Pathogenicity (Chemical Immunology and Allergy, Vol. 81)

The importance of fungal organisms as allergens and pathogens has been increasing considerably over the last decade. This is due, on the one hand, to a general increase in the incidence of allergies, but also to the growing number of immunocompromized individuals such as AIDS patients or transplant recipients. This book summarizes what is currently known about the allergens of Candida, Aspergillus, Cladosporium, Alternaria, Coprinus, and Psilocybe, among others, and describes the application of recombinant allergens for diagnosis and new forms of therapy. The virulence factors and defense mechanisms against Aspergillus and Candida infections are discussed as are the various causes of superficial skin infections with fungi and the aerobiology of fungal spores and mycelia. A comprehensive chapter on fungal toxins and their importance for human and animal health is included, followed by a summary of the present state of fungal genome sequencing. Finally, the now generally accepted new sequence-based systematics and phylogeny of allergenic and pathogenic fungi is presented. A glossary explains the highly specialized terminology of clinical and systematic mycology for the nonspecialist. Summarizing the most up-to-date molecular and clinical findings, this publication will be of interest not only to allergologists, mycologists and biologists, but to all clinicians who want to learn more about clinically important fungi as well as to lawyers concerned with lawsuits on ‘sick building syndrome’.

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A Practical Guide to Clinical Virology 2nd Edition

This Second Edition of A Practical Guide to Clinical Virology is a practical, highly illustrated, quick reference guide to clinical virology. It brings together the essentials of the subject in a entertaining and informative style, describing in turn the clinical features, the symptoms and signs of each of the viral diseases, as well as summarising the epidemiology, laboratory diagnosis and therapy in each case. This book also includes general chapters on classification, diagnosis of infection, antiviral drugs, vaccines and different clinical syndromes.

Key Features:

  • Chapter summaries for quick reference
  • Cartoon illustrations
  • Comprehensive coverage
  • Clear and concise format

Each chapter is easy to read and well organised, ensuring that this is an invaluable textbook for all medical, biomedical, microbiology and applied biology students. In addition, it provides an excellent reference for nurses, occupational health and infection control departments, public health and diagnostic laboratories.

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