Category: Clinical Skills

Interpreting ECGs in Clinical Practice

This book is designed to teach healthcare professionals how to interpret electrocardiograms, presenting this information with numerous illustrations, solid practical content, questions to prompt critical thinking, case presentations, and plentiful practice ECG tracings to promote the application of skills.Interpreting ECGs in Clinical Practice is practical book rather than a “theoretical book.” Although there is plenty of detail, the coverage is to the point, telling the reader the salient points and then showing what needs to be taken away. The breadth of information ranges from simple to complex, but regardless of how advanced the material, the explanations and visuals make the concepts easy to understand, making this a critical resource for all cardiology professionals

 

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Efficacy Analysis in Clinical Trials an Update: Efficacy Analysis in an Era of Machine Learning

Machine learning and big data is hot. It is, however, virtually unused in clinical trials. This is so, because randomization is applied to even out multiple variables

Modern medical computer files often involve hundreds of variables like genes and other laboratory values, and computationally intensive methods are required

This is the first publication of clinical trials that have been systematically analyzed with machine learning. In addition, all of the machine learning analyses were tested against traditional analyses. Step by step statistics for self-assessments are included

The authors conclude, that machine learning is often more informative, and provides better sensitivities of testing than traditional analytic methods do

 

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Clinical Cases in Coronary Rotational Atherectomy: Complex Cases and Complications

This concise practical guide is designed to facilitate the clinical decision-making process in the management of rotational atherectomy procedures by reviewing a number of cases and defining the various diagnostic and management decisions open to clinicians. It will be well illustrated but concise, enabling the reader to obtain relevant information regarding both standard and unusual cases in a rapid, easy to digest format. Each case will also include a narrative description and patient management tips.

Rotational atherectomy (‘rotablator’) is used to treat heavily calcified lesions within coronary arteries at the time of percutaneous coronary intervention (PCI). Lesions that are inadequately treated may not be dilatable by balloons; and stents that are implanted in such lesions are at high risk for acute stent thrombosis and stent failure. However, rotablator therapy is high risk and present unique challenges to the interventionalists. Complications are generally uncommon. However, when they do occur, they tend to be disastrous.

In this case book, we present a series of rotablator cases: basic, complex cases, difficult cases, complications and unusual situations. Although PCI operators all have some degree of experience with this therapy, each operator is unlikely to have significant experience given the cost of the device and the risk involved. Therefore, this book will provide interventionalists with a valuable compendium of cases which can help them in the management of patients whom they plan to treat with rotational atherectomy.

 

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Clinical Investigation (Advances in Experimental Medicine and Biology Book 1047)

Clinical investigation plays an essential role in the differential diagnosis, biomarker development, and therapy and cure of diseases. The book presents a bench-to-bed approach, with broad empirical coverage by experienced practitioners. The articles include topics like cytokine receptors in lung cancer, conduciveness of oxidative stress to carcinogenesis, safety and effectiveness of surgical correction of deformed chest, diagnostic and treatment regimens in inflammation-ridden obstructive lung conditions, alterations in growth hormone secretion leading to disorders of growth and metabolism, microbiota transplantation in pediatric patients, and the promising markers of renal epithelial injury. Yet another issue concerns the restructuring of chronic pain management by establishing the community-based specialized pain clinics. The book aims to disseminate and deliberate on the latest interdisciplinary medical knowledge to enhance clinical outcomes. Being a blend of clinical investigation and practice the book is addressed to physicians, scientists, and allied health care professionals.

 

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Hypertension: from basic research to clinical practice: Volume 2

Hypertension: from basic research to clinical practice” contains a unique collection of selected chapters written by experts and enthusiasts engaged in research and treatment of hypertension, a condition that affects around a billion people in the world. The chapters describe fundamental researches at cellular and molecular levels to the science, and art of treatment of the condition in clinical practice. The topics included ranges from pathophysiology of hypertension, through monitoring of hypertension, to the treatment of hypertension in different patient categories. It contains essential background information as well as cutting edge research, and state of the art treatment alternatives in this broad field. From the beginners, and research students to the expert clinicians, and established scientists, everybody has something to learn from this book.

 

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Dementia in Clinical Practice: A Neurological Perspective: Studies in the Dementia Clinic

Dementia in Clinical Practice: A Neurological Perspective addresses neurological contributions to the diagnosis and management of dementia through a longitudinal examination of the work undertaken in dedicated neurological dementia clinics.

This concise, pragmatic handbook covers:

The use of cognitive screening instruments and their diagnostic utility.

The use of non-cognitive (functional, behavioural, neurovegetative) screening instruments and  their diagnostic utility.

The use of other diagnostic investigations: neuroimaging, neurophysiology, neuropathology.

The diagnostic mix in terms of both neuropsychological syndromes and neurological diagnoses.

The use of conventional treatments for dementia.

The impact of national directives (e.g. NICE, National Dementia Strategy) on day-to-day clinical practice.

Dementia in Clinical Practice: A Neurological Perspective is an illustrated, practical resource for medical professionals involved in the assessment and management of dementia patients. It is of particular benefit to neurologists, psychiatrists, geriatricians, primary care practitioners and those working in the fields of neuropsychology, psychology, occupational therapy, speech and language therapy and nursing.

 

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Neuroprotective Therapy for Stroke and Ischemic Disease

A critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in academia and industry, to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only about 30% of patients are “cured” by available treatments. In 5 sections, the proposed volume will explore historical and novel neuroprotection mechanisms and targets, new and combination therapies, as well as clinical trial design for some of the recent bench-side research.

 

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This book provides an understanding of the challenges that individuals with Autism Spectrum Disorder (ASD) face in receiving medical care and helps equip medical professionals to overcome these challenges to provide high quality, compassionate medical care to this population. The book is divided into two sections. The first provides a broad perspective, providing background about the health care needs of patients with ASD and potential barriers to care that they may experience, as well as an overview of general principles in the delivery of care for patients with ASD. In the second section, the text focuses on specific medical issues and specialties, taking a systems-based approach to cover every major area of medical care. Each of these chapters discusses the problems in that area of medicine that are commonly encountered in the ASD population and the best approaches to managing these issues.

 

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