Radiofrequency Treatments on the Spine 1st ed. 2017 Edition

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This book describes the principles and applications of radiofrequency treatments for various spinal indications, including disc herniation, discogenic and radicular pain, facet joint arthropathy, and benign and malignant lesions of the vertebral column. The aim is to provide a handy guide that will acquaint readers with all aspects of radiofrequency neurotomy at different levels of the spine, enabling them to carry out treatments effectively and safely.

Radiofrequency neurotomy, or radiofrequency ablation, is a minimally invasive procedure that is associated with a reduction in complications, side effects, and risks of anesthesia as well as with lower costs. This book, written by world-renowned authorities in the field, fills a significant gap in the literature by specifically focusing on the use of radiofrequency for spinal conditions. It will be of value to a range of specialists, including interventional neuroradiologists and radiologists, neurosurgeons, and orthopedists.

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Cellular Analysis by Atomic Force Microscopy 1st Edition

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Despite substantial evidence showing the feasibility of Atomic Force Microscopy (AFM) to identify cells with altered elastic and adhesive properties, the use of this technique as a complementary diagnostic method remains controversial. This book is designed to be a practical textbook that teaches how to assess the mechanical characteristics of living, individual cells by AFM. Following a step-by-step approach, it introduces the methodology of measurements in the case of both determination of elastic properties and quantification of adhesive properties.

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PET/CT in Melanoma (Clinicians’ Guides to Radionuclide Hybrid Imaging) 1st ed. 2017 Edition

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About the Author

PET and SPECT in Psychiatry

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PET and SPECT in Psychiatry showcases the combined expertise of renowned authors whose dedication to the investigation of psychiatric disease through nuclear medicine technology has achieved international recognition. The classical psychiatric disorders as well as other subjects – such as suicide, sleep, eating disorders, and autism – are discussed and the latest results in functional neuroimaging are detailed. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all who have an interest in the field of neuroscience, from the psychiatrist and the radiologist/nuclear medicine specialist to the interested general practitioner and cognitive psychologist. It is the first volume of a trilogy on PET and SPECT imaging in the neurosciences; other volumes will focus on PET and SPECT in neurology and PET and SPECT of neurobiological systems.

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Stereotactic Body Radiation Therapy: Principles and Practices

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This book serves as a practical guide for the use of stereotactic body radiation therapy in clinics. On the basis of more than 10 years of clinical experience with lung cancer, liver cancer and other cancers, a remarkable volume of knowledge has been accumulated. At the same time, great progress in techniques has been achieved. Various new fixing apparatuses, new respiratory regulation techniques, new dose fractionation schedules and new image-guided radiation therapy machines have been developed. This book reviews the history of those developments and reports on various types of toxicities. Review of recent clinical studies is also included. The authors were key members of the JCOG 0403 clinical trials on stereotactic body radiation therapy (SBRT) for both inoperable and operableT1N0M0 primary lung cancer. Readers will learn of the superior outcomes obtained with SBRT for lung cancer and other cancers in terms of local control and toxicities. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists and senior nurses as well as medical oncologists and surgical oncologists who are interested in radiotherapy.

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Synopsis of Pathophysiology in Nuclear Medicine

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From the Back Cover

Radiation Therapy for Extranodal Lymphomas 1st ed. 2017 Edition

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This book is devoted to sharing the knowledge and experience of expert radiation therapy (RT) for extranodal lymphomas. For that purpose, the authors provide clinical-pathological information, precise RT techniques, and treatment results, i.e., disease control and survival, of all extranodal lymphomas.

Over the past 10 years, specific techniques have been updated, from 3-dimensional conformal RT to intensity modulated RT / volumetric-modulated arc therapy. Precise targeting such as image-guided RT and active breathing control are now capable of treating lymphoma lesions that shift with respiration or peristalsis.

This book, serving as a guide, provides the necessary knowledge for radiation oncology, practice, and planning involving the RT techniques of treating extranodal lymphomas. In addition, it equips oncologists, hematologists, and medical oncologists to refer patients with extranodal lymphomas to radiation oncologists for appropriate treatment in a timely manner. Therefore this volume will greatly benefit all oncologists, including radiation and medical oncologists, as well as hematologists.

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Cancer Biology and the Nuclear Envelope: Recent Advances May Elucidate Past Paradoxes (Advances in Experimental Medicine and Biology)

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“Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE  is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer.”

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Radiation Therapy for Liver Tumors: Fundamentals and Clinical Practice 1st ed. 2017 Edition

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The management of liver tumors is a nexus of interactions among multiple medical specialties, including radiation oncology. A multitude of liver-directed therapies are available for patients, ranging from surgery and liver transplantation to intra-arterial therapies, thermal ablation procedures, systemic therapies, and radiation treatments. With the introduction of hypofractionated irradiation, particle therapy, and radioembolization, there is growing interest in the use of radiation as a treatment for liver malignancies.

This book examines basic principles of the management of liver tumors.  The evolving roles of x-ray and particle therapies as well as radioembolization in the treatment of liver tumors is the main focus.  A theme of multidisciplinary management is also emphasized, as surgical, interventional and systemic therapies are reviewed.

A unique resource that discusses the role of radiation treatment in the context of other liver-directed therapies, Radiation Therapy for Liver Tumors is of broad interest to radiation oncologists, surgeons, hepatologists, medical oncologists, and radiologists.

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Stereotactic Body Radiation Therapy: Principles and Practices

[amazon template=iframe image2&asin=4431563008]

This book serves as a practical guide for the use of stereotactic body radiation therapy in clinics. On the basis of more than 10 years of clinical experience with lung cancer, liver cancer and other cancers, a remarkable volume of knowledge has been accumulated. At the same time, great progress in techniques has been achieved. Various new fixing apparatuses, new respiratory regulation techniques, new dose fractionation schedules and new image-guided radiation therapy machines have been developed. This book reviews the history of those developments and reports on various types of toxicities. Review of recent clinical studies is also included. The authors were key members of the JCOG 0403 clinical trials on stereotactic body radiation therapy (SBRT) for both inoperable and operableT1N0M0 primary lung cancer. Readers will learn of the superior outcomes obtained with SBRT for lung cancer and other cancers in terms of local control and toxicities. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists and senior nurses as well as medical oncologists and surgical oncologists who are interested in radiotherapy.

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