Space Physiology and Medicine: From Evidence to Practice 4th ed. 2016 Edition

As space medicine evolved from the late 1950s onward, the need arose for a ready reference for students and practitioners on the basic concepts of this new specialty. Through three editions edited by leaders in the development of space medicine, this classic text has met the need. This fourth edition of Space Physiology and Medicine provides succinct, evidence-based summaries of the current knowledge base in space medicine and serves as a source of information on the space environment, responses, and practices. Additionally, there is extensive online material available for each chapter, featuring overviews and self-study questions.

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Corneal Topography in Clinical Practice Pentacam System: Basics and Clinical Interpretation 2nd Edition

Corneal topography is a non-invasive medical imaging technique for mapping the surface curvature of the cornea, the outer structure of the eye. This procedure may be carried out with a Pentacam, which uses a rotating camera to create a 3D image of the anterior of the eye. This second edition has been fully updated to provide the latest developments in corneal topography and tomography using the Pentacam machine. Beginning with an introduction, the following sections describe the fundamentals of corneal topography and use of the Pentacam with different ophthalmic disorders. With nearly 250 high quality, colour images and illustrations, this concise guide is especially useful to graduate and postgraduate students in learning how to read and interpret corneal topography.

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Clinical Oral Anatomy: A Comprehensive Review for Dental Practitioners and Researchers 1st ed. 2017 Edition

This superbly illustrated book presents the most current and comprehensive review of oral anatomy for clinicians and researchers alike. In 26 chapters, the reader is taken on a unique anatomical journey, starting with the oral fissure, continuing via the maxilla and mandible to the tongue and floor of the mouth, and concluding with the temporomandibular joint and masticatory muscles. Each chapter offers a detailed description of the relevant anatomical structures and their spatial relationships, provides quantitative morphological assessments, and explains the relevance of the region for clinical dentistry. All dental health care professionals require a sound knowledge of anatomy for the purposes of diagnostics, treatment planning, and therapeutic intervention. A full understanding of the relationship between anatomy and clinical practice is the ultimate objective, and this book will enable the reader to achieve such understanding as the basis for provision of the best possible treatment for each individual patient as well as recognition and comprehension of unexpected clinical findings.

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Primary Immunodeficiency Diseases: Definition, Diagnosis, and Management 2nd ed. 2017 Edition

The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.

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Orthopedic and Trauma Findings: Examination Techniques, Clinical Evaluation, Clinical Presentation 1st ed. 2017 Edition

This book is a practical, step-by-step guide to orthopedic examination and diagnosis. The author explains a systematic classification of clinical findings that has proven very useful in diagnosing orthopedic disorders in daily routine. The approach to examination begins with a checklist covering the complete patient history, including subjective descriptions of complaints. This is followed by a stepwise approach to physical examination of the patient and collection of clinical findings. Photographs and illustrations clearly depict the necessary examination techniques. The main symptoms are then determined from the patient history and clinical findings, leading to a diagnosis. An overview of all relevant orthopedic conditions for each region of the body facilitates differential diagnosis and thereby completes the examination findings. This book will be of particular value for new residents in orthopedics and trauma but will also be useful for the experienced physician as a means of refreshing knowledge or as a reference.

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Emergencies of the Orbit and Adnexa 1st ed. 2017 Edition

This handbook on orbital, lacrimal and eyelid emergencies deals with such situations in a practical manner guiding the ophthalmologists in accurate handling and making them more proficient and confident in managing vision and life-threatening emergencies. With 51 chapters and more than 350 images, this book covers all the eye emergencies that generalist and specialist ophthalmologists can expect to come across in their day to day practices.

It can be argued that the orbit can no more be called ‘Pandora’s Box’ because of the unpredictable nature of its contents. This perception has changed over the years due to the advent of improved diagnostic, in particular, imaging techniques. However, since medical residency provides very little exposure to orbital and adnexal disorders, most clinicians are inexperienced and unsure about their management. Facing an emergency situation where improper management can rapidly worsen the condition leading to blindness or even death of the patient is every ophthalmologist’s nightmare. The emergent nature of these conditions does not always provide for a leeway to refer these patients to an orbit and oculoplasty specialist, who are few and far between. By the time the patient reaches his destination, his vision maybe irrevocably lost. The legal implications of such mismanagement can be significant too.

This book is a quick and essential resource to manage and refer eye emergencies with confidence

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Clinical Assessment and Examination in Orthopedics 2nd Edition

This second edition is a concise guide to clinical assessment and examination in orthopaedics. Beginning with an introduction to history taking and clinical examination, the following chapters discusses the examination of different parts of the body. Each chapter discusses clinical diagnostic tests relevant to the specific region, as well as common conditions, symptoms and signs. With almost 250 illustrations on demonstration techniques and clinical pictures with diagnosis and examination techniques, this new edition sets out the sequence of examination in a more practical, step by step way than the previous edition.

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Emergencies in Neuro-Ophthalmology: A Case Based Approach 1st Edition

The management of emergent neuro-ophthalmic conditions can be a life-saving encounter for the general ophthalmologist. This book covers life-threatening scenarios that a general ophthalmologist might encounter, and is designed to help the ophthalmologist make emergency triage decisions for initial evaluation and treatment of potentially vision- or life-threatening conditions. This book is case based, and provides the reader with the invaluable expert views of two neuro-ophthalmologists. One, Dr Lee is an ophthalmology-based neuro-ophthalmologist and the other, Dr Brazis is a neurology-based neuro-ophthalmologist. Dr Mughal and Dr Policeni collected and collated the case vignettes during their fellowship with Dr Lee at the University of Iowa Hospitals and Clinics.

This textbook provides a concise, easy to read, and practical guide to the emergent evaluation of neuro-ophthalmic conditions. It is designed to be a quick read and not to be all-inclusive or comprehensive. The reader is directed to longer and more comprehensive neuro-ophthalmic texts for this information. It is also not the aim of the book to provide information on anatomy, pharmacology, physiology, or other basic mechanisms of disease. Instead, this text is meant to be a quick reference and resource for the clinician in the emergency room or in the clinic facing a potentially vision- or life-threatening emergency and to provide immediate guidance for potentially “high stakes” decision making. The case vignettes are based upon real clinical cases but the clinical details of each case have been modified for teaching purposes and represent composite rather than individual histories.

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Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad 1st Edition

The science and applied approaches of enzyme inhibition in drug discovery and development

Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development.

With chapters written by over fifty leading experts in their fields, Enzyme Inhibition in Drug Discovery and Development fosters a cross-fertilization of pharmacology, drug metabolism, pharmacokinetics, and toxicology by understanding the “good” inhibitions—desirable pharmacological effects—and “bad” inhibitions—drug–drug interactions and toxicity. The book discusses:

  • The drug discovery process, including drug discovery strategy, medicinal chemistry, analytical chemistry, drug metabolism, pharmacokinetics, and safety biomarker assessment
  • The manipulations of drug metabolizing enzymes and transporters as well as the negative consequences, such as drug–drug interactions
  • The inhibition of several major drug target pathways, such as the GPCR pathway, the NFkB pathway, and the ion channel pathway

Through this focused, single-source reference on the fundamentals of drug discovery and development, researchers in drug metabolism and pharmacokinetics (DMPK) will learn and appreciate target biology in drug discovery; discovery biologists and medicinal chemists will also broaden their understanding of DMPK.

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Human Body Odor: Etiology, Treatment, and Related Factors

Strong body odor is a condition for which, until now, there have been few treatment methods. The Japanese authors, encouraged by the willingness of Oriental patients to undergo radical treatment, have developed the subcutaneous tissue shaving method, which eliminates the condition in a very short period of time without ugly scarring. The book Human Body Odor not only introduces the completely new subcutaneous tissue shaving method, it also questions conventional theories on the hair cycle itself and throws a new hypothesis about the process of hair generation and regeneration into the scientific arena. This could even lead in the future to a formula for retarding hair loss! Developed over the past twenty years, the authors’ new surgical method for the radical treatment of bromidrosis represents a landmark in cosmetic surgery and dermatology!

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