Anticancer Therapeutics: From Drug Discovery to Clinical Applications 1st Edition

An integrated presentation of the basic science and clinical applications of anticancer agents

Aimed at both undergraduate and postgraduate readers, this unique text provides readers with a fully-integrated presentation of all aspects of the science of anticancer drugs, including their chemistry, pharmacology, and clinical applications.

After heart disease, cancer is the number one killer worldwide, and the tumor microenvironment is forever changing, creating an ever-greater demand for safer, more effective anticancer agents. In response to that demand, the $100 billion cancer drug market continues to grow, with our increased understanding of cancer leading to new drugs being used clinically almost every year.

Anticancer Therapeutics is divided into three sections. Section 1 is an introduction to cancer and therapeutics, and covers the etiology and cellular and molecular basis of cancer. In Section 2, the authors focus on the anticancer agents — their discovery, synthesis, mode of action, mechanisms of resistance, and adverse reactions. Section 3 focuses on specific cancers, explaining how and why the various agents discussed in Section 2 are used, both individually and in combination, to treat different cancers.

• Integrates aspects of basic science, including chemistry and pharmacology and clinical medicine in relation to cancer therapeutics

• Written by an author team comprising specialists in medicinal chemistry, pharmacology, and oncology
• Features full-color images throughout illustrating how drugs bind to cellular targets and exert their pharmacological effect
• Divided into three sections, covering the etiology and cellular and molecular basis of cancer, anticancer agents, and drug applications for different cancers.

Providing the reader with an integrated understanding of all aspects of the science of anticancer agents, this is an ideal textbook for undergraduates studying medicine, nursing, medicinal chemistry, pharmacy, pharmacology and other allied heath / life sciences. It is also a valuable bench reference for pharmacists, medics, and pharmaceutical researchers working in both academia and industry.

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Transfusion Medicine 5th Edition

Explore this concise and clinically focused approach to the field of blood banking and transfusion therapy  

The Fifth Edition of Transfusion Medicine delivers a succinct, thorough, clinically focused, practical and authoritative treatment of a full range of topics in transfusion therapy. This ranges from issues with the blood supply, recruitment of both whole blood and apheresis donors, blood collection and storage, blood testing, blood safety, and transmissible diseases. This edition has been fully updated and revised to include exciting cellular therapies for cancer, transplantation of both hematopoietic cells and solid organs, infectious diseases and regenerative medicine.       

The Fifth Edition includes new authors with highly relevant content that provides a solid grounding for readers in the field. The book:  

• Is an approachable comprehensive guide to the field of blood banking and transfusion medicine 
• Provides complete and timely perspective on  crucial topics, including the HLA system in transfusion medicine and transplantation and quality programs in blood banking and transfusion medicine 
• Is extensively referenced, making it simple for readers to conduct further research on the topics of interest to them  
• Includes new chapters on pediatric transfusion medicine and pathogen reduction  
• Has an expended chapter on patient blood management 
• Provides extensive discussions of the clinical use of blood transfusion in a wide variety of clinical situations including recent development In the management of acute traumatic blood loss   
• Provides updated information about blood groups and molecular testing making inroads into clinical practice along with discussions of laboratory detection of blood groups and provision of red cells  

Perfect for all those working in the field of blood banking, transfusion medicine and hematology or oncology and fellows in pathology, hematology, surgery and anesthesiology. Transfusion Medicine is a good introduction for technologists specializing in blood banking and non-medical personnel working in areas related to hematology and transfusion medicine. Transfusion Medicine will also earn a place in the libraries of practicing pathologists with responsibility for  blood banks. 

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Step-Up to Medicine (Step-Up Series) 5th Edition

Find what you need to know—fast This bestselling volume in the popular Step-Up series provides a high-yield review of medicine, ideal for preparing for clerkships or clinical rotations, shelf exams, and the USMLE Step 2. Clinical pearls, full-color illustrations, and “Quick Hits” provide essential information in an efficient, easy-to-remember manner to help you excel on your exams and succeed in the clinical setting. Also includes a 100-question practice exam to support preparation. 

• Updated and revised content reflects extensive research with faculty and students.
• Figures, charts, tables, graphs, and mnemonics aid visual learners and facilitate retention of essential material.
• Enhanced high-yield outline format and Quick Hits save time and help students review more efficiently.
• 100-question practice exam helps students prepare for shelf and board.
• Succinct, outline approach keeps “extra” material to a minimum, focusing on the core content students need to know.
• Clinical pearls help students “file away” clinical connections for handy retrieval at test time and aid in the transition from basic science to clinical medicine.
• Easy-to-follow algorithms demonstrate examples of effective clinical reasoning, particularly for similar complaints.
• Coverage includes every essential area of medicine, including body system diseases and disorders; fluids, electrolytes, and acid-base disorders; hematologic diseases and neoplasms; infectious diseases; diseases of the skin and hypersensitivity disorders; and ambulatory medicine.
• Helpful appendices cover radiographic and electrocardiogram interpretation, physical examination pearls, workup and management of common problems on the wards, basic statistics and evidence-based medicine, and end-of-life issues and informed consent.

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Principles and Practice of Sleep Medicine – 2 Volume Set 7th Edition

Offering today’s most authoritative, comprehensive coverage of sleep disorders, Kryger’s Principles and Practice of Sleep Medicine, 7th Edition, is a must-have resource for sleep medicine specialists, fellows, trainees, and technicians, as well as pulmonologists, neurologists, and other clinicians who see patients with sleep-related issues. It provides a solid understanding of underlying basic science as well as complete coverage of emerging advances in management and treatment for a widely diverse patient population. Evidence-based content, hundreds of full-color illustrations, and a wealth of additional resources online help you make well-informed clinical decisions and offer your patients the best possible care.

• Contains new chapters on sleep in intersex and transgender individuals; sleep telemedicine and remote PAP adherence monitoring; and sleep and the menstrual cycle, as well as increased coverage of treatment and management of pediatric patients. 
• Includes expanded sections on pharmacology, sleep in individuals with other medical disorders, and methodology. 
• Discusses updated treatments for sleep apnea and advancements in CPAP therapy. 
• Offers access to 95 video clips online, including expert interviews and sleep study footage of various sleep disorders. 
• Meets the needs of practicing clinicians as well as those preparing for the sleep medicine fellowship examination or recertification exams, with more than 950 self-assessment questions, answers, and rationales online. 
• Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

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Pharmacology: Connections to Nursing Practice 4th Edition

For courses in pharmacology.
A patient-centered approach to pharmacology in nursing practice
Pharmacology: Connections to Nursing Practicelinks pharmacology to nursing practice and patient care. Features illuminate connections between pharmacology and nursing practice, from patient scenarios and practice applications, to lifespan considerations, alternative therapies, and gender and cultural influences. The use of prototype drugs helps nurses learn a vast range of medications, while organization by body systems and diseases places drugs in the context of their therapeutic applications. The 4th edition includes more than 30 new FDA-approved drugs, more than 20 new visuals clarifying concepts, and a new feature developing the clinical decision-making skills of advanced practice nurses.

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Essentials of Pharmacology for Dentistry (Covering the latest Curriculum) 4th Edition

•The book is oriented to provide core and contemporary pharmacological knowledge, easily assimilated by dental students
•Written as per the syllabus prescribed by the Dental Council of India
•The book is divided into three sections.
•The first describes the general pharmacological principles with which all professionals involved in drug therapy must be conversant.
•The second on systemic pharmacology presents a brief account of drugs acting on various organ systems
•The third section covers antimicrobials and other drugs which the dentists usually prescribe or administer themselves.
•Leading trade names and dosage forms of drugs generally prescribed by dentists are mentioned distinctively.
•A separate chapter covers drug and aids specific for dental care is incorporated
•Another chapter on management and treatment of common medical emergencies is included
•Application of analgesics and NSAIDs in dental pain, local anaesthetics for dental anaesthesia, role of each class of antimicrobials in orodental infections, prophylaxis of postextraction wound infection and endocarditis in patients at special risk are emphasized.
•Eye catching hierarchical drug classification charts which help create pictorial memory
•Latest NACO guidelines for post-exposure prophylaxis (PEP) of HIV infection for health workers
•Thoroughly revised and updated chapters, including recently introduced drugs.

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