Bone, Biomaterials & Beyond

The introduction of osseointegrated dental implants soon 50 years ago has indeed revolutionized dentistry. The scientific evaluation of their use has shown good and increasingly successful treatment outcomes. A prerequisite though is the availability of sufficient bone volumes to ensure integration and acceptable aesthetic results.
In this book various surgical techniques, using different augmentation materials, are described and explained. The aim has been to highlight minimally invasive surgical techniques, which leads to less risk of morbidity and reduces treatment time.
Readers will enjoy a comprehensive atlas providing some practical advices for every day surgical practice based on solid scientific evidence.

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Hearing Science Fundamentals, Second Edition 2nd Edition

NOTE: This book comes with supplementary content on a PluralPlus companion website. If you purchase or rent a used copy of the printed book, the code to access the website printed inside the book may have been previously redeemed/used or be incorrect and you will not be able to use it. To guarantee access to the website, it is recommended you purchase a new copy of this book.

Hearing Science Fundamentals, Second Edition maintains the straightforward style of the previous edition, introducing the basic concepts in hearing science in an easy-to-understand format. With a wide variety of student-friendly features and instructor resources, this comprehensive textbook facilitates the absorption of technical material by both undergraduate and graduate students.

The text is divided into four clear sections to cover everything from the physics of sound to the anatomy and physiology of the auditory pathway and beyond. The textbook begins by delving into the basics of acoustics and digital signal processing (DSP). In the next section, readers will find full coverage of the basic anatomy and physiology of the auditory mechanism. The third section contains eight chapters on psychoacoustics and how sound is perceived via the auditory pathways. The book wraps up with a brand-new section devoted to pathologies of the auditory mechanisms.

New to the Second Edition

• New coauthor, Jeremy J. Donai, AuD, PhD, brings his extensive clinical and research experience to the concepts discussed

Nine new chapters, including

• Review of Speech Acoustics (Chapter 2)
• Digital Signal Processing (Chapter 3)
• Binaural Processing (Chapter 8)
• Temporal Processing (Chapter 10)
• Signal Detection Theory (Chapter 13)
• Auditory Perception and Hearing Impairment (Chapter 14)
• Separate and expanded chapters for Pathologies of the Auditory Mechanism (Chapter 9) from first edition.

  • Pathologies of the Conductive Auditory Mechanism (Chapter 15)

  • Pathologies of the Sensory Auditory Mechanism (Chapter 16)

  • Pathologies of the Central Auditory Mechanism (Chapter 17)

• Clinical Notes intended to bridge the gap from classroom to hearing clinic have been added throughout the text
• Vocabulary Checks throughout all the chapters
• Evidence-based information incorporated throughout the text
• Updated Recommended Readings list
• Ancillary materials accessible on a PluralPlus companion website: a sample syllabus, test bank, and PowerPoint lecture slides for instructors, and practice quizzes, word-building and anatomy-labelling exercises, audio examples, and overview lecture videos for students

Key Features

• Learning objectives and key terms at the beginning of each chapter prepare the student for the chapter contents
• Two-color anatomical and line illustrations aid understanding of important technical concepts
• Q & A boxes reinforce important information presented in the text
• A glossary of important terms

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Multiple Sclerosis Therapeutics 4th Edition

This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.

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How to request a test: A clinician’s guide to the interpretation and evaluation of medical tests

Medical tests consume considerable resources and yet making requests is often left to the most junior members of the team. Medical schools often under prepare junior doctors for these tasks so they tend to request large numbers of tests to make sure ‘all bases are covered’ by the time a more senior colleague attends to the patient.

Beginning with naïve questions such as ‘what is a medical test?’ and ‘why do we perform tests?’, the book also covers the evaluation of tests from a public health perspective and helps the readers to determine whether a test should be introduced into clinical care. By describing the basics of medical decision making based on probability thresholds, students will learn how to avoid unnecessary testing when results are unlikely to influence patient relevant decisions, and the pros and cons of using metrics such as sensitivity, specificity, and predictive values.

Illustrated throughout with real life examples from multiple medical and surgical specialties, it concludes with a novel checklist for doctors to consider every time they think of requesting a test.

Written by a clinician for clinicians, this book is ideal for medical students and junior doctors. It provides everything they need to know to become experts at requesting tests. It will support them in requesting the most appropriate and effective tests, and inform them on how to interpret results, improving patients’ outcomes.

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Comprehensive Textbook on Vitiligo 1st Edition

Vitiligo is a disorder having a significant impact in dark-skinned individuals. Along with the historical, cultural, and psychological aspects of the disease the multifactorial pathogenesis of this disorder is discussed in detail with special emphasis on the newer hypotheses proposed in the causation. Descriptions of the clinical aspects of the disease are supplemented with clinical photographs covering the latest therapeutic and surgical treatment options. Nonconventional treatments such as cosmetic camouflage and tattooing are also discussed. Topics of controversy such as the role of diet, patient selection for surgery, and so on, are covered in depth.

Key Features

• Discusses the recent advances in treatment

• Evidence-based approach

• Quality of life and psychological aspects covered

• Nonconventional treatment options included with practical tips on vitiligo surgery

• Controversial topics covered

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The Metaphysics of Biology (Elements in the Philosophy of Biology)

This Element is an introduction to the metaphysics of biology, a very general account of the nature of the living world. The first part of the Element addresses more traditionally philosophical questions – whether biological systems are reducible to the properties of their physical parts, causation and laws of nature, substantialist and processualist accounts of life, and the nature of biological kinds. The second half will offer an understanding of important biological entities, drawing on the earlier discussions. This division should not be taken too seriously, however: the topics in both parts are deeply interconnected. Although this does not claim to be a scientific work, it does aim to be firmly grounded in our best scientific knowledge; it is an exercise in naturalistic metaphysics. Its most distinctive feature is that argues throughout for a view of living systems as processes rather than things or, in the technical philosophical sense, substances.

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Evolution, Morality and the Fabric of Society (Elements in the Philosophy of Biology) 

Recent interest in the evolution of the social contract is extended by providing a throughly naturalistic, evolutionary account of the biological underpinnings of a social contract theory of morality. This social contract theory of morality (contractevolism) provides an evolutionary justification of the primacy of a moral principle of maximisation of the opportunities for evolutionary reproductive success (ERS), where maximising opportunities does not entail an obligation on individuals to choose to maximise their ERS. From that primary principle, the moral principles of inclusion, individual sovereignty (liberty) and equality can be derived. The implications of these principles, within contractevolism, are explored through an examination of patriarchy, individual sovereignty and copulatory choices, and overpopulation and extinction. Contractevolism is grounded in evolutionary dynamics that resulted in humans and human societies. The most important behavioural consequences of evolution to contractevolism are reciprocity, cooperation, empathy, and the most important cognitive consequences are reason and behavioural modification.

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Mechanisms in Molecular Biology (Elements in the Philosophy of Biology) 

The new mechanistic philosophy is divided into two largely disconnected projects. One deals with a metaphysical inquiry into how mechanisms relate to issues such as causation, capacities and levels of organization, while the other deals with epistemic issues related to the discovery of mechanisms and the intelligibility of mechanistic representations. Tudor Baetu explores and explains these projects, and shows how the gap between them can be bridged. His proposed account is compatible both with the assumptions and practices of experimental design in biological research, and with scientifically accepted interpretations of experimental results.

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Inheritance Systems and the Extended Evolutionary Synthesis (Elements in the Philosophy of Biology)

Current knowledge of the genetic, epigenetic, behavioural and symbolic systems of inheritance requires a revision and extension of the mid-twentieth-century, gene-based, ‘Modern Synthesis’ version of Darwinian evolutionary theory. We present the case for this by first outlining the history that led to the neo-Darwinian view of evolution. In the second section we describe and compare different types of inheritance, and in the third discuss the implications of a broad view of heredity for various aspects of evolutionary theory. We end with an examination of the philosophical and conceptual ramifications of evolutionary thinking that incorporates multiple inheritance systems.

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Lippincott Illustrated Reviews: Cell and Molecular Biology (Lippincott Illustrated Reviews Series) 2nd Edition

Selected as a Doody’s Core Title for 2022!

Efficiently master essential cell and molecular biology information!
Now in its second edition, Lippincott Illustrated Reviews: Cell and Molecular Biology continues to provide a highly visual presentation of essential cell and molecular biology, focusing on topics related to human health and disease. It offers all the most popular features of the bestselling Lippincott Illustrated Reviews series, including abundant full-color, annotated illustrations, chapter overviews, an expanded outline format, chapter summaries, and review questions that link basic science to real-life clinical situations.

• Master all the latest cell and molecular biology knowledge, thanks to revisions throughout, including updated unit overviews and chapter summaries, which set goals for understanding and re-emphasize essential concepts from each chapter.
• Understand the practical applications with clinical boxes that reinforce key concepts by direct application to real-world scenarios, now with expanded information on specific cellular processes.
• Visualize key concepts more clearly with the aid of nearly 250 full-color, annotated illustrations.
• Extend your learning online with access to new animations and an interactive question bank.

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