Strain Variation in the Mycobacterium tuberculosis Complex: Its Role in Biology, Epidemiology and Control (Advances in Experimental Medicine and Biology) 1st ed

Strain Variation in the Mycobacterium tuberculosis Complex: Its Role in Biology, Epidemiology and Control (Advances in Experimental Medicine and Biology)

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Epidemiology and the People’s Health: Theory and Context 1st Edition

Epidemiology is often referred to as the science of public health. However, unlike other major sciences, its theoretical foundations are rarely articulated. While the idea of epidemiologic theory may seem dry and arcane, it is at its core about explaining the people’s health. It is about life and death. It is about biology and society. It is about ecology and the economy. It is about how myriad aspects of people’s lives – involving work, dignity, desire, love, play, conflict, discrimination, and injustice – become literally incorporated into our bodies and manifest in our health status, individually and collectively. And it is about essential knowledge critical for improving the people’s health and minimizing inequitable burdens of disease, disability, and death.

Woven from a vast array of schools of thought, including those in the natural, social, and biomedical sciences, epidemiologic theory is a rich tapestry whose time for analysis is long overdue. By tracing its history and contours from ancient societies on through the development of – and debates within – contemporary epidemiology worldwide, Dr. Krieger shows how epidemiologic theory has long shaped epidemiologic practice, knowledge, and the politics of public health. Outlining an ecosocial theory of disease distribution that situates both population health and epidemiologic theory in societal and ecologic context, she offers a more holistic picture of how we embody the human experience.

This concise, conceptually rich, and accessible book is a rallying cry for a return to the study and discussion of epidemiologic theory: what it is, why it matters, how it has changed over time, and its implications for improving population health and promoting health equity. It should be required reading for all epidemiologists, or anyone involved in the study of human health and well-being.

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Adult T-cell Leukemia/Lymphoma 1st ed. 2017 Edition

This book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of non-Hodgkin lymphoma. Given the small number of patients, enrollment in clinical trials has not been feasible, and establishing treatment standard has been difficult but new evidence, such as results of nationwide studies on transplantation, have shown new insights and potential treatments. Based on recent evidence, the book presents new treatment methods for ATL and infection prevention of HTLV-1, enabling clinicians, researchers and post-docs specializing in hematology and virology to gain a valuable overview of the disease.

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Cancer Epidemiology: Volume 1, Host Susceptibility Factors (Methods in Molecular Biology) (v. 1) 2009th Edition

Population studies and epidemiology facilitate the discovery of genetic and environmental determinants of cancer and the development of new approaches to cancer control and prevention, therefore they play a central role in the creation of health policies. Cancer Epidemiology compiles areas of research which cover etiological factors or determinants that contribute to the development of cancer and describe the latest technologies in cancer epidemiology. In Volume 1, Host Susceptibility Factors, leading experts provide chapters on cancer incidence, prevalence, mortality and surveillance, methods, technologies and study design in cancer epidemiology as well as host susceptibility factors in cancer epidemiology. Although a non-standard volume of the highly successful Methods in Molecular Biology™ series, this comprehensive text retains the commitment of the series to collecting the kind of detailed, up-to-date information and implementation advice that is crucial for getting optimal results.

Cutting-edge and essential, Cancer Epidemiology allows readers to get the maximum advantage of the methods involved in this exciting and important field.

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Seven Modern Plagues: and How We Are Causing Them 2nd Edition

Epidemiologists are braced for the big one: the strain of flu that rivals the pandemic of 1918-1919, which killed at least 20 million people worldwide. In recent years, we have experienced scares with a host of new influenza viruses: bird flu, swine flu, Spanish flu, Hong Kong flu, H5N1, and most recently, H5N7. While these diseases appear to emerge from thin air, in fact, human activity is driving them. And the problem is not just flu, but a series of rapidly evolving and dangerous modern plagues.
According to veterinarian and journalist Mark Walters, we are contributing to-if not overtly causing-some of the scariest epidemics of our time. Through human stories and cutting-edge science, Walters explores the origins of seven diseases: mad cow disease, HIV/AIDS, Salmonella DT104, Lyme disease, hantavirus, West Nile, and new strains of flu. He shows that they originate from manipulation of the environment, from emitting carbon and clear-cutting forests to feeding naturally herbivorous cows “recycled animal protein.”

Since Walters first drew attention to these “ecodemics” in 2003 with the publication of Six Modern Plagues, much has been learned about how they developed. In this new, fully updated edition, the author presents research that precisely pinpoints the origins of HIV, confirms the link between forest fragmentation and increased risk of Lyme disease, and expands knowledge of the ecology of West Nile virus.

He also explores developments in emerging diseases, including a new chapter on flu, examining the first influenza pandemic since the Hong Kong flu of 1968; a new tick-borne infection in the Mid-West; a second novel bird flu in China; and yet a new SARS-like virus in the Middle East.

Readers will not only learn how these diseases emerged but the conditions that make future pandemics more likely. This knowledge is critical in order to prevent the next modern plague.

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Primary Sclerosing Cholangitis: Current Understanding, Management, and Future Developments 1st ed. 2017 Edition

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This text provides a state-of-the art review of primary sclerosing cholangitis (PSC). The volume focuses on new data about risk factors for PSC, its natural history of the disease, and the epidemiology and genetics of PSC, while providing a comprehensive overview on current and future therapies for PSC, management of cholangiocarcinoma, and other hepatobiliary malignancies. It also touches upon up-to-date surgical and endoscopic management, including liver transplantation- both deceased donor and living related liver transplantation.
Written by experts in the field, Primary Sclerosing Cholangitis: Current Understanding, Management, and Future Developments is a valuable resource for clinicians, surgeons and researchers with an interest in biliary liver disease, inflammatory bowel disease, and liver transplantation.
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World Atlas of Epidemic Diseases (Arnold Publication)

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The euphoria about the defeat of epidemics which surrounded the global eradication of smallpox in the 1970s proved short-lived. The advent of AIDS in the following decade, the widening spectrum of other newly-emergent diseases (from Ebola to Hanta virus), and the resurgence of old diseases such as tuberculosis and malaria all suggest that the threat of epidemic diseases remains at an historic high. The World Atlas of Epidemic Diseases provides a timely and scholarly review of over fifty of the most important such diseases at the start of the twenty-first century.

This stunningly presented collection of maps, illustrations and commentary offers an authoritative overview of the global distribution of major epidemic diseases on a variety of spatial scales from the local to the global. The Atlas is arranged in an historical sequence, beginning with classic plagues such as the ‘Black Death’ and cholera and moving on through smallpox and measles to ‘modern’ diseases such as AIDS and Legionnaires’ disease. Over 400 figures are incorporated, including 150 specially drawn maps supported by micrographs of the causative agents, photographs of the disease vectors, historical prints and graphs of changing incidence. The text for each disease includes discussion of its nature and epidemiological features, its origin (where known) and historical impacts, and its global status at the start of the twenty-first century. The book concludes with an informed look towards the future, assessing the probable impacts of major medical advances on life expectancy and the chances of success of programmes for the global eradication of diseases such as polio and measles.

The World Atlas of Epidemic Diseases makes a major new contribution to our knowledge of the global burden of disease and is an informative and fascinating reference on the changing distributions of disease. It will be an invaluable resource for anyone interested in the spread, control and eradication of epidemic disease.

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Emerging Infectious Diseases: A Guide to Diseases, Causative Agents, and Surveillance (Public Health/Epidemiology and Biostatistics

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This important resource offers a comprehensive introduction to emerging and reemerging infectious disease, including the underlying mechanisms of microbial emergence, the technology used to detect them and the strategies available to contain them. The author describes the diseases and their causative agents that are major factors in the health of populations the world over. One of the main features of the book is its broad coverage of 25 different emerging infectious diseases, most of which are directly important to those practicing health in the U.S. The book is designed for students in epidemiology, global health, and biology.

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The Essentials of Biostatistics for Physicians, Nurses, and Clinicians Paperback – 19 Aug 2011

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Designed specifically for healthcare practitioners who need to understand basic biostatistics but do not have much time to spare, The Essentials of Biostatistics for Physicians, Nurses and Clinicians presents important statistical methods used in today′s biomedical research and provides insight on their appropriate application. Rather than provide detailed mathematics for each of these methods, the book emphasizes what healthcare practitioners need to know to interpret and incorporate the latest biomedical research into their practices.

The author draws from his own experience developing and teaching biostatistics courses for physicians and nurses, offering a presentation that is non–technical and accessible. The book begins with a basic introduction to the relationship between biostatistics and medical research, asking the question “why study statistics?,” while also exploring the significance of statisitcal methods in medical literature and clinical trials research. Subsequent chapters explore key topics, including:

  • Correlation, regression, and logistic regression
  • Diagnostics
  • Estimating means and proportions
  • Normal distribution and the central limit theorem
  • Sampling from populations
  • Contingency tables
  • Meta–analysis
  • Nonparametric methods
  • Survival analysis

Throughout the book, statistical methods that are often utilized in biomedical research are outlined, including repeated measures analysis of variance, hazard ratios, contingency tables, log rank tests, bioequivalence, cross–over designs, selection bias, and group sequential methods. Exercise sets at the end of each chapter allow readers to test their comprehension of the presented concepts and techniques.

The Essentials of Biostatistics for Physicians, Nurses, and Clinicians is an excellent reference for doctors, nurses, and other practicing clinicians in the fields of medicine, public health, pharmacy, and the life sciences who need to understand and apply statistical methods in their everyday work. It also serves as a suitable supplement for courses on biostatistics at the upper–undergraduate and graduate levels.

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Modern Epidemiology Third Edition

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The thoroughly revised and updated Third Edition of the acclaimed Modern Epidemiology reflects both the conceptual development of this evolving science and the increasingly focal role that epidemiology plays in dealing with public health and medical problems. Coauthored by three leading epidemiologists, with contributions from sixteen experts in a variety of epidemiologic sub-disciplines, this new edition is by far the most comprehensive and cohesive text on the principles and methods of epidemiologic research. The book covers a broad range of concepts and methods, including epidemiologic measures of occurrence and effect, study designs, validity, precision, statistical interference, and causal diagrams. Topics in data analysis range from Bayesian analysis, sensitivity analysis, and bias analysis, with an extensive overview of modern regression methods including logistic and survival regression, splines, hierarchical (multilevel) regression, propsensity scores and other scoring methods, and g-estimation. Special-topics chapters cover disease surveillance, ecologic studies, social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, nutritional epidemiology, environmental epidemiology, reproductive epidemiology, clinical epidemiology, and meta-analysis.

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